Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes by Anne-Marie L. Wegeberg, Tina Okdahl, Tina Fløyel, Christina Brock, Niels Ejskjaer, Sam Riahi, Flemming Pociot, Joachim Størling, Birgitte Brock

“…Our findings emphasize the importance of the neuroimmune regulatory system in the pathogenesis of neuropathy in type 1 diabetes.…”
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Adolescent mice exposed to TBI developed PD-like pathology in middle age by Rong Sha, Mingzhe Wu, Pengfei Wang, Ziyuan Chen, Wei Lei, Shimiao Wang, Shun Gong, Guobiao Liang, Rui Zhao, Yingqun Tao

“…However, the precise mechanism by which chronic TBI initiates PD pathogenesis is not yet fully understood. In our present study, we assessed the chronic progression and pathogenesis of PD-like behavior at different intervals in TBI mice. …”
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Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic SteatosisSummary by Xiao-lin Wang, Jia-hao He, Ping Xie, Yuan Wu, Ling-yue Dong, Wei An

“…However, the connection between dysregulated ALR crotonylation and MASLD pathogenesis remains largely unknown. Methods: Steatotic liver samples from human and Western diet (WD)-fed mice were employed for detecting Kcr levels. …”
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Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disea... by Yasaman Nazari Hagh, Mohamadreza Ahmadifard, Sedigheh Esmaelzadeh, Soheila Abbaszadeh, Naser Shokrzadeh

“…Some genetic markers play a crucial role in pathogenesis and infertility. Objective: This study investigates the role of miR-200a and miR-223-3p in embryo implantation and their association with EM-related infertility. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…The need for advanced analytical tools to better understand the pathogenesis of cardiovascular disease (CVD) is critical due to its significant impact on public health. …”
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The assessment of the facial skin microbiota in patients with seborrheic dermatitis and metabolic syndrome by Kristina Yu. Molodykh, Elena R. Araviiskaia, Evgeny V. Sokolovskiy, Lyudmila A. Kraeva

“…Currently, the attention of dermatologists is often directed to the study of changes in bacterial colonization of the skin, as one of the important links in the pathogenesis of skin diseases, including psoriasis, atopic dermatitis, acne, and seborrheic dermatitis. …”
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Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae by Tien-Huang Lin, Chen-Yu Wang, Chien-Chen Wu, Ching-Ting Lin

“…However, the role of the Pta-AckA pathway, which regulates AcP levels, in K. pneumoniae pathogenesis remains unclear. Methods: Deletion mutants lacking the pta and ackA, involved in AcP production and hydrolysis, were generated in K. pneumoniae CG43S3. …”
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Dysregulated T Cell Activation and Aberrant Cytokine Expression Profile in Systemic Lupus Erythematosus by Haiyan Zhou, Bojiang Li, Jing Li, Tongqian Wu, Xiaoqian Jin, Rui Yuan, Ping Shi, Yan Zhou, Long Li, Fang Yu

“…Accumulating evidence indicates a critical role for T cells and relevant cytokines in the pathogenesis of systemic lupus erythematosus (SLE). However, the specific contribution of T cells together with the related circulating cytokines in disease pathogenesis and organ involvement is still not clear. …”
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Identification of prognostic biomarkers of sepsis and construction of ceRNA regulatory networks by Guihong Chen, Wen Zhang, Chenglin Wang, Muhu Chen, Yingchun Hu, Zheng Wang

“…Abstract Sepsis is a life-threatening severe organ dysfunction, and the pathogenesis remains uncertain. Increasing evidence suggests that circRNAs, mRNAs, and microRNAs can interact to jointly regulate the development of sepsis. …”
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Distinct Functions of Specialized Dendritic Cell Subsets in Atherosclerosis and the Road Ahead by Alma Zernecke

“…This review focuses on important findings gathered in these studies and dissects the multifaceted contribution of CCL17-expressing DCs and pDCs to the pathogenesis of atherosclerosis. Furthermore, an outlook on future challenges faced when studying DCs in this detrimental disease are provided, and hurdles that will need to be overcome in order to enable a better understanding of the contribution of DCs to atherogenesis are discussed, a prerequisite for their therapeutic targeting in atherosclerosis.…”
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Premenstrual Exacerbation of Life-Threatening Asthma: Effect of Gonadotrophin Releasing Hormone Analogue Therapy by Alun L Edwards, M Sarah Rose, Lois E Donovan, Gordon T Ford

“…The addition of estrogens and progestins at the same time as treatment with GnRH analogue may be of value in determining the role of these hormones in the pathogenesis of menstrually related exacerbations of asthma.…”
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Mycobacterial Infections in AIDS by A Ross Hill

“…Understanding of the pathogenesis and management of mycobacterial diseases should increase rapidly given the renewed research spurred on by the advent of HIV.…”
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An “Engram-Centric” Approach to Transient Global Amnesia (TGA) and Other Acute-Onset Amnesias by Andrew J. Larner

“…Although the clinical phenomenology of TGA is well described, its pathogenesis is not currently understood, thus preventing the development of evidence-based therapeutic recommendations. …”
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Vitiligo treatment: a literature review by Monika J. Leżanko, Adrianna P. Pyrek, Waldemar Placek, Agnieszka Owczarczyk-Saczonek

“…This disease affects from 0.5% to even 4% of the general population and the first symptoms appear before the patient reaches the age of 30 in majority of cases. The pathogenesis involves genetic and immunological factors, adhesion of melanocytes to the epithelium, as well as metabolic factors related to cellular oxidative stress. …”
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Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with Disseminated Mycobacterium avium-intracellulare Infection by Yuria Ablanedo-Terrazas, Christopher E. Ormsby, Gustavo Reyes-Terán

“…We present the first reported case of palatal actinomycosis co-infection with disseminated MAC, in an HIV-infected subject with Kaposi sarcoma and diabetes. We discuss the pathogenesis of the complex condition of this subject.…”
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Primary Biliary Cirrhosis and Type II Autoimmune Polyglandular Syndrome by Mark Ram Borgaonkar, David Geoffrey Morgan

“…The association of PBC with other organ-specific autoimmune diseases supports an immune-mediated pathogenesis and may have implications in further studies of PBC.…”
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Parry–Romberg Syndrome with Uhthoff’s Phenomena: A Spectrum of Autoimmune Disease? by Samuel Asanad

“…Parry–Romberg syndrome (PRS) is a rare disorder characterized by unilateral facial atrophy. Currently, the pathogenesis of PRS is poorly understood and no definitive treatment is available. …”
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Modulation of gut microbiota by dietary macronutrients in type 2 diabetes: a review by Hong Jing Wang, Oumaima Battousse, Amutha Ramadas

“…Potential crucial research concepts could help develop macronutrient-specific diets to modulate gut microbiota beneficial to T2DM management and pathogenesis. …”
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Chronic Pain in Inflammatory Arthritis: Mechanisms, Metrology, and Emerging Targets—A Focus on the JAK-STAT Pathway by Fausto Salaffi, Giovanni Giacobazzi, Marco Di Carlo

“…This paper provides a summary on pain in inflammatory arthritis, from pathogenesis to clinimetric instruments and treatment, with a focus on the JAK-STAT pathway.…”
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Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma by Joao N. Duarte

“…The exact mechanism of retinal ganglion cell loss in the pathogenesis of glaucoma is yet to be understood. Mitochondrial damage-associated molecular patterns (DAMPs) resulting from mitochondrial dysfunction have been linked to Leber’s hereditary optic neuropathy and autosomal dominant optic atrophy, as well as to brain neurodegenerative diseases. …”
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