Antibody-Mediated Rejection: Pathogenesis, Prevention, Treatment, and Outcomes by Olivia R. Blume, Sarah E. Yost, Bruce Kaplan

“…It is important to have an understanding of human-leukocyte antigen (HLA) typing including well-designed studies to determine anti-MHC-class-I-related chain A (MICA) and antibody rejection pathogenesis. This can allow for more specific diagnosis and treatment which may improve long-term graft function. …”
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New Insights into Pathogenesis, Diagnosis, and Treatment of Pancreatic Disorders by Grazyna Rydzewska, Jean Morisset, Davor Stimac

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Esophageal Motility Disorders: Current Concepts of Pathogenesis and Treatment by Peter J Kahrilas

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Corrigendum: Klebsiella pneumoniae biofilms and their role in disease pathogenesis by Maria Eduarda Souza Guerra, Giulia Destro, Brenda Vieira, Alice S. Lima, Lucio Fabio Caldas Ferraz, Anders P. Hakansson, Michelle Darrieux, Thiago Rojas Converso

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Editorial: Viral infection pathogenesis and pathology in nervous system by A. Alwin Prem Anand

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The Role of HMGB1 in the Pathogenesis of Type 2 Diabetes by Yanan Wang, Jixin Zhong, Xiangzhi Zhang, Ziwei Liu, Yuan Yang, Quan Gong, Boxu Ren

“…Given the similarities of inflammatory response in the development of T2D, we will discuss the potential implication of HMGB1 in the pathogenesis of T2D. Importantly, we will summarize and renovate the role of HMGB1 and HMGB1-mediated inflammatory pathways in adipose tissue inflammation, insulin resistance, and islet dysfunction. …”
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The interplay of ferroptosis and oxidative stress in the pathogenesis of aortic dissection by Zhaoshan Zhang, Zhaoshan Zhang, Zhaoshan Zhang, Haichao Wang, Haichao Wang, Haichao Wang, Xi Kan, Xi Kan, Xi Kan, Xiaozhao Zhang, Xiaozhao Zhang, Xiaozhao Zhang, Senping Xu, Senping Xu, Senping Xu, Jie Cai, Jie Cai, Jie Cai, Jiawei Guo, Jiawei Guo, Jiawei Guo

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Role of Farnesoid X Receptor in the Pathogenesis of Respiratory Diseases by Jin-nan Wu, Jian-rong Chen, Jin-liang Chen

“…In recent years, several studies have shown that FXR is widely involved in the pathogenesis of various respiratory diseases, such as chronic obstructive pulmonary disease, bronchial asthma, and idiopathic pulmonary fibrosis. …”
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Role of Subcutaneous Adipose Tissue in the Pathogenesis of Insulin Resistance by Pavankumar Patel, Nicola Abate

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Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment by A. Mišeikaitė, P. Vaitkienė

“…Since the content of the exosomes depends on the cell that secretes them and can change during the progression of the disease, exosome studies can help to understand the pathogenesis and control the course of the disease. There is growing evidence of the importance of exosomes for cell-to-cell communication, mediating the exchange of biological information and substances, and the ability to cross the blood-brain barrier. …”
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HDAC10 and its implications in Sézary syndrome pathogenesis by Monika Pieniawska, Karolina Rassek, Bogumiła Skwara, Magdalena Żurawek, Iwona Ziółkowska-Suchanek, Lydia Visser, Monique Lodewijk, Małgorzata Sokołowska-Wojdyło, Małgorzata Sokołowska-Wojdyło, Berenika Olszewska, Roman J. Nowicki, Roman J. Nowicki, Tomasz Stein, Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Marta Szymoniak-Lipska, Natalia Rozwadowska, Katarzyna Iżykowska

“…Recent genomic studies underscore the role of epigenetic modifiers in CTCL pathogenesis, prompting an investigation into HDAC10, a member of class IIb HDACs, in SS. …”
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Roles for Exosomes in the Pathogenesis, Drug Delivery and Therapy of Psoriasis by Yuchao Chen, Huazhen Liu, Yuming He, Bin Yang, Weihui Lu, Zhenhua Dai

“…In this review, we have summarized recent advances in the biogenesis of exosomes and their potential roles in the pathogenesis and treatment of psoriasis and further discussed their challenges and future directions in psoriasis treatment. …”
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Protease-activated receptor 1 in the pathogenesis of cystic fibrosis by Sarath Ranganathan, Philip Sutton, Sophie Day, Poshmaal Dhar, Kristy Azzopardi, Muhammad A Saeed, Sohinee Sarkar, Jia-Xi Han

“…While PAR1 is known to play an important role in regulating inflammation, nothing is known about any potential role of this receptor in CF pathogenesis.Methods PAR1 (PAR1-/-) and intestinal-corrected CFTR (Cftr-/-) deficient mice were crossed to generate double knock-out (DKO) mutants lacking both PAR1 and CFTR, as well as matching sibling single mutant and wildtype (WT) littermate controls. …”
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Autoimmune hepatitis: new in diagnostics, a pathogenesis and treatment by Ye. N. Shirokova, K. V. Ivashkin, V. T. Ivashkin

“…To generalize new data on diagnostics, pathogenesis and treatment of autoimmune hepatitis (AIH).Original positions. …”
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The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome by Filiz Yarsilikal Guleroglu, Ali Cetin, Goknil Pelin Coskun, Meltem Caliskan, Fulya Karaduman, Can Bilginer, Resat Misirlioglu, Sinem Tekin, Merve Nur Al, Tugce Caklili, Yusuf Tutar

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The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches by Pankita H. Pandya, Mary E. Murray, Karen E. Pollok, Jamie L. Renbarger

“…Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. …”
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The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis by Piotr Wojdasiewicz, Łukasz A. Poniatowski, Dariusz Szukiewicz

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Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis by Yuliya V Yevsyutina, V. T. Ivashkin, E. Z. Abgadzhava

“…To present data on the role of mitochondrial and lysosomal dysfunction in pathogenesis of acute pancreatitis (AP). Summary. Hyperamilasemia, premature intralobular activation of digestive enzymes, accumulation of large vacuoles in acinar cells, activation of proinflammatory mediators, apoptosis and necrosis of acinar cells are the basic pathomorphological signs of AP. …”
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Cellular and Molecular Mediators of Neuroinflammation in the Pathogenesis of Parkinson’s Disease by Sandeep Vasant More, Hemant Kumar, In Su Kim, Soo-Yeol Song, Dong-Kug Choi

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Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers by Yu. O. Shulpekova

“…To demonstrate value of disorders of cholinergic innervation in pathogenesis of irritable bowel syndrome (IBS).Original positions. …”
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