The Natural History of Uterine Leiomyomas: Morphometric Concordance with Concepts of Interstitial Ischemia and Inanosis by Gordon P. Flake, Alicia B. Moore, Norris Flagler, Benita Wicker, Natasha Clayton, Grace E. Kissling, Stanley J. Robboy, Darlene Dixon

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Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression by Daphne Wijnbergen, Mridul Johari, Ozan Ozisik, Peter A.C. ‘t Hoen, Friederike Ehrhart, Anaïs Baudot, Chris T. Evelo, Bjarne Udd, Marco Roos, Eleni Mina

“…Abstract Background Inclusion Body Myositis is an acquired muscle disease. Its pathogenesis is unclear due to the co-existence of inflammation, muscle degeneration and mitochondrial dysfunction. …”
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Evaluation of IL-29 in Euthyroid Patients with Graves’ Orbitopathy: A Preliminary Study by Bogusz Falkowski, Ewelina Szczepanek-Parulska, Nadia Sawicka-Gutaj, Aleksandra Krygier, Marek Ruchala

“…Orbitopathy is the most prevalent and recognizable extrathyroidal manifestation of Graves’ disease with unrevealed pathogenesis. Interleukin 29 (IL-29) is a relatively newly discovered inflammatory cytokine. …”
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Expansion of Circulating T Follicular Helper Cells in Children with Acute Henoch-Schönlein Purpura by Jue Xie, Yan Liu, Lei Wang, Guoxiang Ruan, Huiming Yuan, Hong Fang, Jianyong Wu, Dawei Cui

“…Taken together, these findings suggest that TFH cells and associated molecules might play critical roles in the pathogenesis of HSP, which are possible therapeutic targets in HSP children.…”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

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Urinary phthalate metabolites associated with increased prevalence of gallstone disease in U.S. adults: data from the NHANES study by Feng Jia, Yu Chang, Yuguang Li, Fangqi Li, Xinqiao Chen, Xiangliang Liu, Wei Li, Jiuwei Cui

“…These novel findings suggest phthalate exposure may contribute to lithogenic pathogenesis. Future prospective and mechanistic research is warranted.…”
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Morphological Features and In Vitro Cytopathic Effect of Acanthamoeba griffini Trophozoites Isolated from a Clinical Case by Arturo González-Robles, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, Maria Reyes-Batlle, Carmen M. Martín-Navarro, Jacob Lorenzo-Morales

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Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn’s disease by bioinformatics analysis and machine learning by Wei Chen, Zeyan Xu, Haitao Sun, Wen Feng, Zhenhua Huang

“…Ubiquitination plays a significant role in the pathogenesis of CD. This study aimed to explore the functional roles of ubiquitination-related genes in CD. …”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA.…”
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Assessing the inflammation in pediatric MOGAD: Significance of CSF HMGB1 and related biomarkers by Xin Wang, Ruibin Zhao, Jiayu Fan, Chong Liu, Li Zhang, Huafang Yang, Weiyi Wang

“…Evaluation and monitoring of biomarkers associated with its pathogenesis would provide vital information on disease progression and therapeutic assessment.MethodsWe assessed NLRP3, HMGB1, IL-6, and IL-33 levels in the cerebrospinal fluid (CSF) of pediatric patients with MOGAD at different time points and their association with the risk of disease. …”
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Profiling Proteins in the Hypothalamus and Hippocampus of a Rat Model of Premenstrual Syndrome Irritability by Mingqi Qiao, Peng Sun, Yang Wang, Sheng Wei, Xia Wei, Chunhong Song, Fushun Wang, Jibiao Wu

“…Our findings contribute to understanding the pathogenesis of PMS irritability and could provide a reference point for further studies.…”
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Cytokines in Liver Cirrhosis (Their Importance in Assessing Activity and Decompensation) by G. K. Mirodzhov, S. D. Pulatova

“…Aim: studying the role of pro-inflammatory and anti-inflammatory cytokines in the pathogenesis of liver cirrhosis progression.Materials and methods. …”
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The Clinical Values of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Blood and Thyroid Nodules by Ayfer Altas, Fatih Kuzu, Dilek Arpaci, Mustafa Unal, Murat Can, Figen Barut, Furuzan Kokturk, Sevil Uygun Ilikhan, Taner Bayraktaroglu

“…IGF-1 plays a role in the pathogenesis of various tumors with its mutagenic and antiapoptotic properties. …”
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Virulence is not directly related to strain success in planta in Clavibacter nebraskensis by Molly Veregge, Cory D. Hirsch, Matthew J. Moscou, Liana Burghardt, Peter Tiffin, Devanshi Khokhani

“…To understand the ecology and pathogenesis of the pathogen population, it is essential to study strain dynamics in the context of the host. …”
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INTERRELATION OF PRIONS WITH NON-CODING RNAS by R. N. Mustafin, E. K. Khusnutdinova

“…Some of the activated non-coding RNAs can catalyze the formation of new prions from normal protein, playing their role in the pathogenesis of prion diseases. Confirmation of this assumption is the presence of the association of alleles of microRNA with the development of the disease, which indicates the role of the specific sequences of noncoding RNAs in the catalysis of prion formation. …”
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Molecular-genetic mechanisms of the interaction between processes of cell response to mechanical stress and neuronal apoptosis in primary open-angle glaucoma by O. V. Saik, N. A. Konovalova, P. S. Demenkov, N. V. Ivanisenko, T. V. Ivanisenko, D. E. Ivanoshchuk, O. S. Konovalova, O. A. Podkolodnaya, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…Currently, there is a large number of scientific publications describing proteins and genes involved in the pathogenesis of POAG, including neuronal apoptosis and the cell response to mechanical stress. …”
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Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis by Meng Wang, Licheng Wang, Shusheng Wu, Dongsheng Zhou, Xianming Wang

“…These DEGs were enriched with functional processes and pathways related to HCC pathogenesis. From the PPI network, 5 hub genes were identified. …”
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Iron overload impact on peripheral blood cells, lymphocytes and karyotypes in newly diagnosed myelodysplastic syndromes (MDS) patients: a single-center retrospective analysis by Lixiang Duan, Wenjun Yu, Xiaolin Jiao, Ying Sun, Yao Fang Ma, Le Li, Zeqiang Nie, Dan Zhao

“…Additionally, IOL may contribute to the pathogenesis of MDS by affecting karyotypes.…”
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Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells by David Schnittker, Karen Kwofie, Ali Ashkar, Bernardo Trigatti, Carl D. Richards

“…Accumulating evidence suggests that adventitial fibroblasts play a significant role in contributing to inflammation of the arterial wall and pathogenesis of atherosclerosis. The effects of gp130 cytokines on these cells (including oncostatin M-[OSM] and IL-6), some of which have been implicated in atherosclerosis, are currently unknown. …”
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Hormonal contraception in women with polycystic ovary syndrome: Contraceptive and non-contraceptive effects. A clinical lecture by Olga A. Pustotina

“…The article deals in detail with the PCOS diagnosis algorithm and pathogenesis, as well as the adverse impact of PCOS on the reproductive and overall health of women. …”
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