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641
METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway
Published 2019-01-01“…This study firstly demonstrates the critical role of METTL3 in RA, which provides novel insights into recognizing the pathogenesis of RA and a promising biomarker for RA.…”
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642
Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients
Published 2017-01-01“…It is not diagnosed or managed properly in the majority of patients because its pathogenesis remains controversial. In this study, human whole genome microarrays identified 2898 and 4493 differentially expressed genes (DEGs) in DM and DPN patients, respectively. …”
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643
Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and Osteoporosis
Published 2020-01-01“…MSC functional decline accounts for the pathogenesis of many diseases and, more importantly, limits the large-scale applications of MSCs in regenerative medicine. …”
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644
Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa
Published 2016-01-01“…We explore potential mechanisms by which HGM may be involved in the pathogenesis of GAVE.…”
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645
The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis
Published 2012-01-01“…The role of the process of apoptosis is investigated in the pathogenesis of many autoimmune diseases; however at present, there is not much information about its role in dermatitis herpetiformis. …”
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646
Gut microbiota and atrial cardiomyopathy
Published 2025-02-01“…Recent research has highlighted the critical role of the gut microbiota in the pathogenesis of atrial cardiomyopathy, and this is consistent with the gut–heart axis having major implications for cardiac health. …”
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647
Adipocytokine Associations with Insulin Resistance in British South Asians
Published 2013-01-01“…Adipocytokines are implicated in the pathogenesis of type 2 diabetes and may represent identifiable precursors of metabolic disease within high-risk groups. …”
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648
Mechanism of Ferroptosis and Its Role in Type 2 Diabetes Mellitus
Published 2021-01-01“…In addition, ferroptosis also engages in the pathogenesis of diabetic complications such as myocardial ischemia and diabetic cardiomyopathy (DCM). …”
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649
The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma
Published 2020-01-01“…The aim of our manuscript is to present an updated point of view on the involvement of beta HPV types in cSCC pathogenesis.…”
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650
The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis
Published 2010-01-01“…In this study, it was hypothesized that apoptosis might play an important role in the pathogenesis of SM-induced lung injury via Fas-FasL signaling pathway. …”
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651
Lipedema: Clinical Features, Diagnosis, and Management
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652
Interleukin-17A Exacerbates Ferric Chloride-Induced Arterial Thrombosis in Rat Carotid Artery
Published 2014-01-01“…Interleukin-17A (IL-17A), the most widely studied member of the IL-17 cytokine family, is a cytokine which emerged to be critical for host defense as well as in the pathogenesis of autoimmune disorders. Moreover, IL-17A is involved in the pathogenesis of cardiovascular diseases, such as atherosclerosis and acute coronary syndrome and in the cardiovascular risk associated with systemic immunological disorders. …”
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653
Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing
Published 2025-02-01“…These datasets enhance our understanding of PMP pathogenesis and provide a valuable resource for uncovering the intricate molecular landscape of PMP, with the potential to improve clinical utility through further research.…”
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654
Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets
Published 2025-12-01“…Immune cells play a key role in the pathogenesis of AS. This study integrated bioinformatics methods with experimental validation to explore the role of natural killer (NK) cells in AS.Methods Two microarray datasets, GSE25101 and GSE73754, were selected, and the scRNA-seq data were obtained from GSE194315 and Liu’s research. …”
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655
Extracellular vesicles from fifth-stage larval Angiostrongylus cantonensis upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocy...
Published 2025-01-01“…However, the roles of A. cantonensis EVs in modulating parasite pathogenesis and host immune response remain poorly understood. …”
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656
Infiltrative Lung Diseases: Complications of Novel Antineoplastic Agents in Patients with Hematological Malignancies
Published 2008-01-01“…The present review discusses different pulmonary syndromes, pathogenesis and management of these novel agents.…”
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657
Congenital Vallecular Cyst Causing Airway Compromise in a 2-Month-Old Girl
Published 2015-01-01“…The epidemiology, pathogenesis, and clinical presentation of vallecular cysts are discussed as well as the diagnosis and management.…”
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658
Abnormal Hematological Indices in Cirrhosis
Published 2009-01-01“…The present article reviews the pathogenesis, incidence, prevalence, clinical significance and treatment of abnormal hematological indices in cirrhosis.…”
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659
Association of Human Lymphocyte Antigens with Obstructive Airways Disease after Bone Marrow Transplantation
Published 1996-01-01“…The identification of a significant human lymphocyte antigen (HLA) association with the development of OAD might offer some insight into its pathogenesis and serve as a marker to identify prospectively patients at risk for developing OAD.…”
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660
Adherence of Helicobacter pylori to the Gastric Mucosa
Published 1997-01-01“…Bacterial adhesion to the intestinal epithelium is a critical initial step in the pathogenesis of many enteric diseases. …”
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