Bile acids regulation of cellular stress responses in liver physiology and diseases by Tiangang Li, Mohammad Nazmul Hasan, Lijie Gu

“…However, dysregulation of these cellular pathways is often observed in chronic liver diseases, which exacerbates cellular dysfunction to contribute to disease pathogenesis. Therefore, identification of these novel links has significantly advanced our knowledge of bile acid biology and physiology, which is needed to understand the contributions of bile acid dysregulation in disease pathogenesis, establish bile acids as diagnostic markers and develop bile acid-based pharmacological interventions. …”
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Wpływ czynników środowiskowych na powstawanie chorób układu krążenia – wybrane problemy by Janusz Jerzemowski

“…Schetler (70) divided the factors favoring diseases of circulation system into two groups: risk factors (which have admitted participations in pathogenesis of heart and vascular diseases) and environmental factors which significance in pathogenesis of heart diseases still increases. …”
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Activation of TLR4-Mediated NF𝜅B Signaling in Hemorrhagic Brain in Rats by Weiyu Teng, Lishu Wang, Weishuang Xue, Chao Guan

“…Inflammation and immunity play a crucial role in the pathogenesis of Intracerebral hemorrhage (ICH). Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa-B (NF𝜅B) signaling plays critical roles in the activation and regulation of inflammatory responses in injured brain. …”
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Coexistence of giant cell arteritis and subacute thyroiditis: A case report and literature review by Cheng Xu, Yongmei Han

“…Giant cell arteritis and subacute thyroiditis are often regarded as clinically distinct diseases with differing pathogenesis. We report a rare case of coexisting giant cell arteritis and subacute thyroiditis that were both successfully managed using glucocorticoid therapy. …”
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Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets by Stephanie Toth-Manikowski, Mohamed G. Atta

“…Over the past two decades, there has been significant clarification of the various pathways implicated in the pathogenesis of DKD. Nonetheless, very little has changed in the way clinicians manage patients with this disorder. …”
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Cytokines in inflammatory bowel disease by P. L. Beck, J. L. Wallace

“…Over the past decade, much has been learned regarding the role of various cytokines in the pathogenesis of inflammatory bowel disease. Several cytokine ‘knockout’ models in mice have been shown to develop colitis, while alterations in the production of various cytokines has been documented in human Crohn's disease and ulcerative colitis. …”
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Avian Bornaviral Ganglioneuritis: Current Debates and Unanswered Questions by Su L. Boatright-Horowitz

“…Research regarding the pathogenesis and treatment for this disease is ongoing, with implications for understanding other emerging human and nonhuman diseases, as well as the health and ecology of wildlife. …”
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Comparison of Gensini score and SYNTAX score for predicting in-stent restenosis in patients with coronary artery disease and drug-eluting stent implantation by Min-Tao Gai, Shi-Qi Yan, Ming-yuan Wang, Amanguli Ruze, Ling Zhao, Qiu-Lin Li, Bang-Hao Zhao, An-Xia Deng, Su Hu, Xiao-Ming Gao

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General and Specific Genetic Polymorphism of Cytokines-Related Gene in AITD by Chen Xiaoheng, Mei Yizhou, He Bei, Li Huilong, Wang Xin, Hu Rui, Li Lu, Ding Zhiguo

“…These two diseases exhibit similar pathogenesis but opposite trends in the clinical manifestations. …”
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In silico study about β-amyloid’s role in Alzheimer’s disease and glaucoma and prediction of its interactions with glaucoma related proteins by Nancy Maurya

“…This study is an attempt to evaluate the chances of β-amyloid’s role in pathogenesis of retinal neurodegenerative disorder called glaucoma, in silico. …”
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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

“…Additionally, some genes involved in signal regulation or encoding hemicellulose- and cellulose-degrading enzymes and extracellular proteases were commonly upregulated during pathogenesis. Overall, we present some putative key genes and processes that may be crucial for S. lycopersici pathogenesis. …”
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A Relationship between Epithelial Maturation, Bronchopulmonary Dysplasia, and Chronic Obstructive Pulmonary Disease by Abraham B. Roos, Tove Berg, Magnus Nord

“…Recent evidence suggests that defective transcriptional regulation of epithelial differentiation and maturation may contribute to BPD pathogenesis as well as early onset of COPD. The transcriptional regulators CCAAT/enhancer-binding protein (C/EBP)α and C/EBPβ, SMAD family member (Smad)3, GATA binding protein (GATA)6, and NK2 homeobox (NKX)2-1 are reported to be involved in processes contributing to pathogenesis of both BPD and COPD. …”
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Intrathecal Immunoglobulin A Synthesis in Multiple Sclerosis: From Biological Aspects to Clinical Relevance by Dariia Kliushnikova, Ferdinand Otto, Georg Pilz, Peter Wipfler, Andrea Harrer

“…Intrathecal immunoglobulin A (IgA) synthesis in multiple sclerosis (MS) has long earned little attention, despite a potential significance in disease pathogenesis and prognosis. The presence of IgA-positive plasma cells in MS lesions and along damaged axons suggests a role in disease pathogenesis. …”
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Plasma MicroRNA Expression Profiles in Psoriasis by Shiju Xiao, Xin Liu, Xiaoxu Wang, Hongpeng Lv, Junbo Zhao, Xinwei Guo, Fuyang Xian, Yunrun Ji, Guangzhong Zhang

“…Network analysis revealed pivotal deregulated plasma miRNAs and their relevant target genes and pathways regulating psoriasis pathogenesis. Conclusions. This study analysed the expression of plasma miRNAs and their target pathways, elucidating the pathogenesis of psoriasis; these results may be used to design novel therapeutic strategies and to identify diagnostic biomarkers for psoriasis.…”
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Lipid-Induced Mechanisms of Metabolic Syndrome by Yulia K. Denisenko, Oxana Yu Kytikova, Tatyana P. Novgorodtseva, Marina V. Antonyuk, Tatyana A. Gvozdenko, Tatyana A. Kantur

“…Insulin resistance (IR) is the crucial cause of the MetS pathogenesis, which develops against the background of abdominal obesity. …”
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Peran Kemokin dalam Patogenesis Rinitis Alergi by Effy Huriyati, Bestari J Budiman, Ricki Octiza

“…Conclusion: Eotaxin and CCR3 are the major factor in pathogenesis of allergic rhinitis which is involve eosinophil.…”
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Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve by Ramona Schmitt, Anke Tscheuschler, Philipp Laschinski, Philipp Discher, Jana Fuchs, Fabian A. Kari

“…The pathogenesis of ascending thoracic aortic aneurysm (aTAA) is thought to differ between patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV), and one of the causes is different hemodynamics. …”
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Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice by Tianchan Peng, Jian Xiang, Yun Tian, Xiaogen Tang, Lina Wang, Lijuan Gao, Oscar Junhong Luo, Li’an Huang, Guobing Chen

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Post-translational modifications and bronchopulmonary dysplasia by Kun Yang, Ting He, Xue Sun, Wenbin Dong

“…Bronchopulmonary dysplasia is a prevalent respiratory disorder posing a significant threat to the quality of life in premature infants. Its pathogenesis is intricate, and therapeutic options are limited. …”
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Role of Neutrophils in Psoriasis by Wen-Ming Wang, Hong-Zhong Jin

“…In this review, we highlight the role of neutrophils in the pathogenesis of psoriasis.…”
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