Showing 41 - 60 results of 2,971 for search '"pathogenesis"', query time: 0.06s Refine Results
  1. 41

    The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases by César Pacheco-Tena, Susana Aideé González-Chávez

    Published 2015-01-01
    “…Here, we review the pathogenesis of rheumatic diseases such as systemic lupus erythematous, rheumatoid arthritis, spondyloarthritis including ankylosing spondylitis, psoriasis, and Crohn’s disease and provide realistic approaches based on the logic of the danger model. …”
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    Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases by Donatella Comito, Claudio Romano

    Published 2012-01-01
    “…The fundamentals of IBD pathogenesis are considered a defective innate immunity and bacterial killing with overaggressive adaptive immune response. …”
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  6. 46

    Role of Intestinal Transit in the Pathogenesis of Gallbladder Stones by R Hermon Dowling, Martin J Veysey, Stephen P Pereira, S Hyder Hussaini, Linzi A Thomas, John AH Wass, Gerard M Murphy

    Published 1997-01-01
    “…Increasing evidence implicates prolonged intestinal transit (slow transit constipation) in the pathogenesis of conventional gallbladder stones (GBS), and that of gallstones induced by long term octreotide (OT) treatment. …”
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  7. 47

    The Histone Modification Code in the Pathogenesis of Autoimmune Diseases by Yasuto Araki, Toshihide Mimura

    Published 2017-01-01
    “…Autoimmune diseases are chronic inflammatory disorders caused by a loss of self-tolerance, which is characterized by the appearance of autoantibodies and/or autoreactive lymphocytes and the impaired suppressive function of regulatory T cells. The pathogenesis of autoimmune diseases is extremely complex and remains largely unknown. …”
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  8. 48

    Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis by David J. Hackam, Amin Afrazi, Misty Good, Chhinder P. Sodhi

    Published 2013-01-01
    “…In seeking to understand the molecular and cellular processes that lead to NEC development, we have identified a critical role for the receptor for bacterial lipopolysaccharide (LPS) toll like receptor 4 (TLR4) in the pathogenesis of NEC, as its activation within the intestinal epithelium of the premature infant leads to mucosal injury and reduced epithelial repair. …”
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  9. 49

    The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis by Animesh Singh, Sarah Karrar

    Published 2014-01-01
    “…In this review, we present the evidence for the role of host-bacterial interactions in the pathogenesis of joint inflammation with particular emphasis on ReA. …”
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    Oral submucous fibrosis: pathogenesis and therapeutic approaches by Jianfei Tang, Junjie Liu, Zekun Zhou, Xinyan Cui, Hua Tu, Jia Jia, Baike Chen, Xiaohan Dai, Ousheng Liu

    Published 2025-02-01
    “…In addition, we also discuss the role of innate and adaptive immune cells and how they contribute to the pathogenesis of OSF. Finally, we summarize strategies to interrupt key mechanisms that cause OSF, including modulation of the ECM, inhibition of inflammation, improvement of vascular disturbance. …”
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  12. 52

    Apoptosis: Molecular Mechanisms, Regulation and Role in Pathogenesis by Ryan Wei Yan Hung, Anthony W Chow

    Published 1997-01-01
    “…OBJECTIVE: To review the current state of knowledge of apoptosis, with an emphasis on identifying potential and established roles for apoptosis in the pathogenesis of infectious diseases.…”
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  13. 53

    PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma by Osamu Kimura, Yasuteru Kondo, Tooru Shimosegawa

    Published 2012-01-01
    “…Therefore, to clarify the pathogenesis of HCC, we should examine PPAR signaling. …”
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  14. 54

    Gut Microbiota and its Metabolites in Pathogenesis of NAFLD by M. S. Reshetova, O. Yu. Zolnikova, V. T. Ivashkin, K. V. Ivashkin, S. A. Appolonova, T. L. Lapina

    Published 2023-02-01
    “…A more detailed understanding of the role of individual metabolites or their combinations in the NAFLD pathogenesis will allow us to determine the vector of further diagnostic and therapeutic approaches for this nosology. …”
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    Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease by Longgui Ning, Xinhe Lou, Fenming Zhang, Guoqiang Xu

    Published 2019-01-01
    “…The aims of this review are to discuss the roles of several important NRs, such as PPARγ, PXR, vitamin D receptor (VDR), farnesoid X receptor (FXR), and RAR-related orphan receptor gammat (RORγt), in the pathogenesis of IBD and management strategies based on targeting these receptors.…”
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  20. 60

    Understanding the Pathogenesis of Angelman Syndrome through Animal Models by Nihar Ranjan Jana

    Published 2012-01-01
    “…A number of animal models for AS have been generated to understand the disease pathogenesis. The most widely used model is the UBE3A-maternal-deficient mouse that recapitulates most of the essential features of AS including cognitive and motor abnormalities. …”
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