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The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases
Published 2015-01-01“…Here, we review the pathogenesis of rheumatic diseases such as systemic lupus erythematous, rheumatoid arthritis, spondyloarthritis including ankylosing spondylitis, psoriasis, and Crohn’s disease and provide realistic approaches based on the logic of the danger model. …”
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Combat Diabetic Nephropathy: From Pathogenesis to Treatment
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43
Pathogenesis of Functional Biliary Pain and Pharmacology of Trimebutin
Published 2024-03-01Subjects: Get full text
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44
The Role of Macrophages in the Pathogenesis of Inflammatory Bowel Disease
Published 1993-01-01Get full text
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Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases
Published 2012-01-01“…The fundamentals of IBD pathogenesis are considered a defective innate immunity and bacterial killing with overaggressive adaptive immune response. …”
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Role of Intestinal Transit in the Pathogenesis of Gallbladder Stones
Published 1997-01-01“…Increasing evidence implicates prolonged intestinal transit (slow transit constipation) in the pathogenesis of conventional gallbladder stones (GBS), and that of gallstones induced by long term octreotide (OT) treatment. …”
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The Histone Modification Code in the Pathogenesis of Autoimmune Diseases
Published 2017-01-01“…Autoimmune diseases are chronic inflammatory disorders caused by a loss of self-tolerance, which is characterized by the appearance of autoantibodies and/or autoreactive lymphocytes and the impaired suppressive function of regulatory T cells. The pathogenesis of autoimmune diseases is extremely complex and remains largely unknown. …”
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Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis
Published 2013-01-01“…In seeking to understand the molecular and cellular processes that lead to NEC development, we have identified a critical role for the receptor for bacterial lipopolysaccharide (LPS) toll like receptor 4 (TLR4) in the pathogenesis of NEC, as its activation within the intestinal epithelium of the premature infant leads to mucosal injury and reduced epithelial repair. …”
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The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis
Published 2014-01-01“…In this review, we present the evidence for the role of host-bacterial interactions in the pathogenesis of joint inflammation with particular emphasis on ReA. …”
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Editorial: Pathogenesis and clinical treatment of diabetic nephropathy
Published 2025-02-01Get full text
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51
Oral submucous fibrosis: pathogenesis and therapeutic approaches
Published 2025-02-01“…In addition, we also discuss the role of innate and adaptive immune cells and how they contribute to the pathogenesis of OSF. Finally, we summarize strategies to interrupt key mechanisms that cause OSF, including modulation of the ECM, inhibition of inflammation, improvement of vascular disturbance. …”
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Apoptosis: Molecular Mechanisms, Regulation and Role in Pathogenesis
Published 1997-01-01“…OBJECTIVE: To review the current state of knowledge of apoptosis, with an emphasis on identifying potential and established roles for apoptosis in the pathogenesis of infectious diseases.…”
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PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma
Published 2012-01-01“…Therefore, to clarify the pathogenesis of HCC, we should examine PPAR signaling. …”
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Gut Microbiota and its Metabolites in Pathogenesis of NAFLD
Published 2023-02-01“…A more detailed understanding of the role of individual metabolites or their combinations in the NAFLD pathogenesis will allow us to determine the vector of further diagnostic and therapeutic approaches for this nosology. …”
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The Paradox of Feline Coronavirus Pathogenesis: A Review
Published 2011-01-01“…Although the precise cause of FIP pathogenesis remains unclear, some hypotheses have been suggested. …”
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Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis
Published 2022-05-01Subjects: Get full text
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58
Study on the pathogenesis of pathophysiological changes of burn systemic infection
Published 1992-01-01Get full text
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Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease
Published 2019-01-01“…The aims of this review are to discuss the roles of several important NRs, such as PPARγ, PXR, vitamin D receptor (VDR), farnesoid X receptor (FXR), and RAR-related orphan receptor gammat (RORγt), in the pathogenesis of IBD and management strategies based on targeting these receptors.…”
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Understanding the Pathogenesis of Angelman Syndrome through Animal Models
Published 2012-01-01“…A number of animal models for AS have been generated to understand the disease pathogenesis. The most widely used model is the UBE3A-maternal-deficient mouse that recapitulates most of the essential features of AS including cognitive and motor abnormalities. …”
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