Dilated cardiomyopathy signature metabolic marker screening: Machine learning and multi-omics analysis by Xiao-Lei Li, Aibibanmu Aizezi, Yan-Peng Li, Yan-Hong Li, Fen Liu, Qian Zhao, Xiang Ma, Dilare Adi, Yi-Tong Ma

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The Complex Role of STAT3 in Viral Infections by Suresh V. Kuchipudi

“…This review summarized the currently known functions of STAT3 in the regulation of viral replication and pathogenesis of viral infections. Some of the key unanswered questions and the gap in our current understanding of the role of STAT3 in viral pathogenesis are discussed.…”
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Unraveling the relationship between obstructive sleep apnea and osteoarthritis: A multivariate mendelian randomization highlighting the role of BMI as a confounding factor by Xin Xu, Hui Yu, Mingyi Yang, Jiale Xie, Ke Xu, Erliang Li, Xianjie Wan, Jiachen Wang, Guoqiang Wang, Ying Pan, Peng Xu, Junfei Guo

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Within-host evolution of a transcriptional regulator contributes to the establishment of chronic Pseudomonas aeruginosa infection by Ning Zhou, Jingchen Yu, Xujiao Liu, Chengxi Li, Huang Tang, Lin Lyu, Chengwei Wu, Yana Chen, Jian Zhang, Jinjing Ni, Danni Wang, Jing Tao, Wenjuan Wu, Yu Zhang, Yun Feng, Yanjie Chao, Jie Lu, Ping He, Yu-Feng Yao

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PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia by Sarawin Harnchoowong, Poonkiat Suchonwanit

“…In this review article, we discuss the pathogenesis of PCA with a focus on PPAR-γ involvement in pathogenesis of lichen planopilaris (LPP), the most common lymphocytic form of PCA. …”
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Pituitary adenoma: a literature review by A. Sidaraitė, B. Glebauskienė, R. Liutkevičienė

“…Nevertheless, its pathogenesis remains unclear – familial cases and syndromes are known better than sporadic cases. …”
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Current Prospects of Herbal STW 5 Agent in Treatment of Functional Gastrointestinal Diseases by A. A. Sheptulin

“…A limited remediation in most common functional GI diseases, functional dyspepsia (FD) and irritable bowel syndrome (IBS), is conditioned by their multifactorial pathogenesis. Meanwhile, most specific medicines only target selected pathogenesis components, thus warranting a multitarget agent development. …”
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eEF-2K Deficiency Boosts the Virus-Specific Effector CD8⁺ T Cell Responses During Viral Infection by Liqing Wang, Benny Shone Song, Rayansh Poojary, Xiaofang Xiong, Xingcong Ren, Jin-Ming Yang, Jianxun Song

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MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…This study presents evidence indicating that miR-155 plays a key role in the pathogenesis of IBD for the different genders. MiR-155 was upregulated and showed proinflammatory activity, whereas GPER1 showed an anti-inflammatory response during the pathogenesis of IBD. …”
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Nasopharyngeal Carcinoma Signaling Pathway: An Update on Molecular Biomarkers by Warut Tulalamba, Tavan Janvilisri

“…Furthermore, understanding in molecular pathogenesis is still lacking, pondering the identification of effective prognostic and diagnostic biomarkers. …”
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Genetic causality between insomnia and specific orthopedic conditions: Insights from a two-sample Mendelian randomization study by Mingyi Yang, Jiale Xie, Yani Su, Ke Xu, Pengfei Wen, Xianjie Wan, Hui Yu, Zhi Yang, Lin Liu, Peng Xu

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Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study by Talaiti Tuergan, Talaiti Tuergan, Aimitaji Abulaiti, Alimu Tulahong, Alimu Tulahong, Ruiqing Zhang, Ruiqing Zhang, Zhongdian Yuan, Zhongdian Yuan, Yanze Lin, Yanze Lin, Yingmei Shao, Yingmei Shao, Yingmei Shao, Tuerganaili Aji, Tuerganaili Aji

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Shifting paradigms in primary aldosteronism: reconsideration of screening strategy via integrating pathophysiological insights by Takumi Kitamoto, Yutaro Ruike, Hisashi Koide, Kosuke Inoue, Yoshiro Maezawa, Masao Omura, Kazuki Nakai, Yuya Tsurutani, Jun Saito, Katsuhiko Kuwa, Koutaro Yokote, Tetsuo Nishikawa

“…The frequency is influenced by the screening strategy and should be based on understanding the pathogenesis of PA. Progress has been made to promote our understanding of the pathogenesis of PA by the findings of aldosterone driver mutations, which have been found in normotensives and hypertensives. …”
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Autophagy in Inflammatory Diseases by Alexander J. S. Choi, Stefan W. Ryter

“…Mutations in autophagy-related genes, leading to loss of autophagic function, have been implicated in the pathogenesis of Crohn's disease. Furthermore, autophagy-dependent mechanisms have been proposed in the pathogenesis of several pulmonary diseases that involve inflammation, including cystic fibrosis and pulmonary hypertension. …”
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Inflammation in Heart Failure: Mechanisms and Therapeutic Strategies by Jiang Yu, Guoxiang Zhou, Yongzheng Guo, Yang Long

“…Despite recent advancements in understanding of HF pathogenesis and treatment, the prognosis of patients with HF remains poor. …”
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Early peripheral blood gene expression (Cyp4A11 and Cyp2E1) in cases of brain ischemia in addict cases admitted to Benha university hospital by Nashwa E. Ahmed, Amina M. Nagah, Omima R. Mohamed, Ghada Mohamed Mahmoud, Sania K. Elwia

“…Understanding the molecular mechanisms underlying stroke pathogenesis in drug users can improve diagnosis and treatment. …”
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Molecular and Serological Investigation of Equine Herpesvirus Type 1 (EHV-1) and Type 4 (EHV-4) in Horses In Ibagué, Tolima by Julieth Michel Petano-Duque, Edwin Urueña-Martinez, Laura Liliana Cabezas-Callejas, Jorge Perilla-Amaya, Valentina Rueda-García, Iang Schroniltgen Rondón-Barragán, Ricaurte Lopera-Vásquez

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16S rRNA sequencing-based evaluation of the protective effects of key gut microbiota on inhaled allergen-induced allergic rhinitis by Yi Tang, Yongchuan She, Danping Chen, Yibo Zhou, Dan Xie, Zhai Liu

“…IntroductionAllergic rhinitis (AR) is a common respiratory disorder influenced by various factors in its pathogenesis. Recent studies have begun to emphasize the significant role of gut microbiota in immune modulation and its potential association with the development of AR. …”
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Macular Amyloidosis and Epstein-Barr Virus by Yalda Nahidi, Naser Tayyebi Meibodi, Zahra Meshkat, Narges Nazeri

“…Macular amyloidosis is limited to the skin, and several factors have been proposed for its pathogenesis. Detection of Epstein-Barr virus (EBV) DNA in this lesion suggests that this virus can play a role in pathogenesis of this disease. …”
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Molecular genetics of idiopathic pulmonary fibrosis by R. N. Mustafin

“…Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic instability, mitochondrial dysfunction, loss of proteostasis) are involved in the pathogenesis of IPF. The pathogenesis of IPF consists of TGF-β activation, epithelial-mesenchymal transition, and SIRT7 expression decrease. …”
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