ER Stress and Lipid Metabolism in Adipocytes by Beth S. Zha, Huiping Zhou

“…The role of endoplasmic reticulum (ER) stress is a rapidly emerging field of interest in the pathogenesis of metabolic diseases. Recent studies have shown that chronic activation of ER stress is closely linked to dysregulation of lipid metabolism in several metabolically important cells including hepatocytes, macrophages, β-cells, and adipocytes. …”
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Autoimmune and iodine deficiency diseases of the thyroid gland as the "tip of the iceberg" of multiple organ pathology by Ekaterina A. Troshina

“…The article presents modern data on the etiology, pathogenesis, diagnosis and treatment of autoimmune and iodine deficiency diseases in the context of possible associations with other autoimmune and non-autoimmune somatic pathologies. …”
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Role of serotonin in physiology and diseases of gastro-intestinal tract by E. F. Barinov, O. N. Sulayeva

“…It determines its involvement in pathogenesis of the diseases related to disorders of motility, microcirculation, inflammation and disregeneration. …”
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Differential Expression Profiles of mRNA and Noncoding RNA and Analysis of Competitive Endogenous RNA Regulatory Networks in Nonalcoholic Steatohepatitis by Mengjia Gao, Jingxin Xin, Xiaoling Li, Ling Gao, Shanshan Shao, Meng Zhao

“…The present study reveals novel circRNA biomarkers of NASH and reports a potential competing endogenous RNA (ceRNA) regulatory network that might provide insights for further investigation into the underlying pathogenesis of NASH.…”
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Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases by Gunnar K. Gouras

“…It will be important to better understand the molecular and cellular mechanisms governing the role of these aggregating proteins in neural function, especially at synapses, how their propagation occurs and how pathogenesis is promoted by aging.…”
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Risk factor assessment of prediabetes and diabetes based on epidemic characteristics in new urban areas: a retrospective and a machine learning study by Li Xu, Xiangcheng Sun, Ning Wang, Yiyi Wang, Yan Li, Chuan Zhang

“…Abstract To explore in depth the characteristics of the risk factors for diabetes and prediabetes pathogenesis and progression in special regions. We investigated medical data from 160 thousand cases in the newly developing urban area of a large modern city from 2015 to 2021. …”
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Glutathione S-Transferase Omega-2 and Transforming Growth Factor-β1 Polymorphisms in Iranian Glaucoma Patients by Shahram Bamdad, Fatemeh Sanie-Jahromi, Marzieh Alamolhoda, Nasrin Masihpour, Mohammad-Hossein Karimi

“…In contrast, the CT genotype of TGF-β1 is suggested to be a protective genetic factor against the pathogenesis of glaucoma.…”
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The Role of Digital Fluorescence in Acne Vulgaris: Correlation of Ultraviolet Red Fluorescence with the Severity of Acne Vulgaris by Imam Budi Putra, Nelva K. Jusuf, Nani Kumala Dewi

“…Digital fluorescence has been found useful in pathogenesis investigation and treatment evaluation. …”
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The complexity of mucosal damage in gastroesophageal airway reflux disease: A molecular perspective by Sheng Chen, Min Wang, Shuai Zhang, Xin Huang, Xinke Sui, Dou Li, Changqing Zhong, Wei Wu

“…Over the years, major progress has been made in the understanding of the molecular pathogenesis of reflux associated mucosal inflammation, suggesting a complex and multifactorial pathogenesis and immune-mediated effects. …”
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Changes in the Microbiome During Chronic Rhinosinusitis by Mateusz de Mezer, Nina Chalama, Cheyanna Bratt, Melanie Kiebalo, Natalia Dolata, Jan Rogaliński, Małgorzata Leszczyńska

“…This review aims to explore the interrelation of microbial residents in the pathogenesis and chronicity of the diseased sinonasal environment.…”
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Genetic Polymorphisms: A Novel Perspective on Acute Pancreatitis by Yong Chen, Chao Lian Xie, Ran Hu, Cheng Yi Shen, Mei Zeng, Chang Qiang Wu, Tian Wu Chen, Chen Chen, Meng Yue Tang, Hua Dan Xue, Zheng Yu Jin, Xiao Ming Zhang

“…For many decades, it has compelled researchers to explore the exact pathogenesis and the understanding of the pathogenesis of AP has progressed dramatically. …”
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Expression of H2S in Gestational Diabetes Mellitus and Correlation Analysis with Inflammatory Markers IL-6 and TNF-α by Yucui Teng, Shuxia Xuan, Ming Jiang, Li Tian, Jinjing Tian, Qian Chang

“…The current study expands the knowledge base regarding H2S and provides new avenues for exploring further the pathogenesis of GDM.…”
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Metabolism-Related Adipokines and Metabolic Diseases: Their Role in Osteoarthritis by Zhang Q, Zhao YX, Li LF, Fan QQ, Huang BB, Du HZ, Li C, Li W

“…However, OA is more than just a wear and tear disease; its aetiology is complex, and its pathogenesis is poorly understood. Metabolic syndrome (MetS) has emerged as a critical driver of OA development. …”
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Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity by Jiaqi Ma, Cory M. Ayres, Chad A. Brambley, Smita S. Chandran, Tatiana J. Rosales, W. W. J. Gihan Perera, Bassant Eldaly, William T. Murray, Steven A. Corcelli, Evgenii L. Kovrigin, Christopher A. Klebanoff, Brian M. Baker

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The Application of Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography in Macular Diseases by Jing Wang, Lian-Rong Yin

“…The choroid plays an essential role in the pathogenesis of various posterior segment diseases. However, traditional imaging methods still have limited cross-sectional observation of choroid. …”
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Vibrio parahaemolyticus: spread, detection and identification techniques by G. S. Skitovich, N. B. Shadrova, O. V. Pruntova

“…The paper presents V. parahaemolyticus biological properties, pathogenesis peculiarities, their spread and detection techniques.…”
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Update on Myopia Risk Factors and Microenvironmental Changes by Valeria Coviltir, Miruna Burcel, Alina Popa Cherecheanu, Catalina Ionescu, Dana Dascalescu, Vasile Potop, Marian Burcea

“…The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. …”
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Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy by Motoko Sasaki, Yasuni Nakanuma

“…The autoimmune-mediated pathogenesis of bile duct lesions, including the significance of AMAs, triggers of the autoimmune process, and so on remain unclear. …”
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Overview of Mink Immunity and Resistance to Pseudomonas aeruginosa by Jiangsong Bai, Xiao Wang, Zihui Zhang, Pengjing Lian, Jian Qiao

“…Many previous mink studies have investigated the pathology, pathogenesis, serology, antimicrobial resistance, virulence gene, vaccination, and related diseases of P. aeruginosa. …”
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The Function of Necroptosis and Its Treatment Target in IBD by Francis Atim Akanyibah, Yi Zhu, Tao Jin, Dickson Kofi Wiredu Ocansey, Fei Mao, Wei Qiu

“…Necroptosis is associated with IBD pathogenesis, leading to intestinal barrier abnormalities and uncontrolled inflammation. …”
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