Showing 461 - 480 results of 2,971 for search '"pathogenesis"', query time: 0.06s Refine Results
  1. 461

    A Quarter Century of Liver Transplantation: Learning from Livers by Paul C. Adams

    Published 1989-01-01
    “…Recurrence of the primary disease in the liver following transplantation has furthered understanding of the pathogenesis of hepatitis and the cell biology of hepatobiliary tumours. …”
    Get full text
    Article
  2. 462

    PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration by Weixing Xu, Rana Dhar, Danyang Zheng, Qi Peng, Yue Li, Sheng Mei, Huifang Tang

    Published 2025-02-01
    “…In the IDD rat model, PDE4 inhibitor roflumilast, ferroptosis inhibitor Fer-1, or Nrf2 activator dimethyl fumarate (DMF) delayed IDD pathogenesis. While administration of ferroptosis inducer elastin enhanced IDD pathogenesis. …”
    Get full text
    Article
  3. 463

    Application of Proteomics to Inflammatory Bowel Disease Research: Current Status and Future Perspectives by Arash Assadsangabi, Caroline A. Evans, Bernard M. Corfe, Alan Lobo

    Published 2019-01-01
    “…Despite recent advances in decoding the pathophysiology of IBD, many questions regarding disease pathogenesis remain. Genome-wide association studies (GWAS) and knockout mouse models have significantly advanced our understanding of genetic susceptibility loci and inflammatory pathways involved in IBD pathogenesis. …”
    Get full text
    Article
  4. 464

    Wpływ czynników środowiskowych na powstawanie chorób układu krążenia – wybrane problemy by Janusz Jerzemowski

    Published 2009-06-01
    “…Schetler (70) divided the factors favoring diseases of circulation system into two groups: risk factors (which have admitted participations in pathogenesis of heart and vascular diseases) and environmental factors which significance in pathogenesis of heart diseases still increases. …”
    Get full text
    Article
  5. 465

    Activation of TLR4-Mediated NF𝜅B Signaling in Hemorrhagic Brain in Rats by Weiyu Teng, Lishu Wang, Weishuang Xue, Chao Guan

    Published 2009-01-01
    “…Inflammation and immunity play a crucial role in the pathogenesis of Intracerebral hemorrhage (ICH). Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa-B (NF𝜅B) signaling plays critical roles in the activation and regulation of inflammatory responses in injured brain. …”
    Get full text
    Article
  6. 466

    Coexistence of giant cell arteritis and subacute thyroiditis: A case report and literature review by Cheng Xu, Yongmei Han

    Published 2025-02-01
    “…Giant cell arteritis and subacute thyroiditis are often regarded as clinically distinct diseases with differing pathogenesis. We report a rare case of coexisting giant cell arteritis and subacute thyroiditis that were both successfully managed using glucocorticoid therapy. …”
    Get full text
    Article
  7. 467

    Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets by Stephanie Toth-Manikowski, Mohamed G. Atta

    Published 2015-01-01
    “…Over the past two decades, there has been significant clarification of the various pathways implicated in the pathogenesis of DKD. Nonetheless, very little has changed in the way clinicians manage patients with this disorder. …”
    Get full text
    Article
  8. 468

    Cytokines in inflammatory bowel disease by P. L. Beck, J. L. Wallace

    Published 1997-01-01
    “…Over the past decade, much has been learned regarding the role of various cytokines in the pathogenesis of inflammatory bowel disease. Several cytokine ‘knockout’ models in mice have been shown to develop colitis, while alterations in the production of various cytokines has been documented in human Crohn's disease and ulcerative colitis. …”
    Get full text
    Article
  9. 469

    Avian Bornaviral Ganglioneuritis: Current Debates and Unanswered Questions by Su L. Boatright-Horowitz

    Published 2020-01-01
    “…Research regarding the pathogenesis and treatment for this disease is ongoing, with implications for understanding other emerging human and nonhuman diseases, as well as the health and ecology of wildlife. …”
    Get full text
    Article
  10. 470

    General and Specific Genetic Polymorphism of Cytokines-Related Gene in AITD by Chen Xiaoheng, Mei Yizhou, He Bei, Li Huilong, Wang Xin, Hu Rui, Li Lu, Ding Zhiguo

    Published 2017-01-01
    “…These two diseases exhibit similar pathogenesis but opposite trends in the clinical manifestations. …”
    Get full text
    Article
  11. 471

    In silico study about β-amyloid’s role in Alzheimer’s disease and glaucoma and prediction of its interactions with glaucoma related proteins by Nancy Maurya

    Published 2023-08-01
    “…This study is an attempt to evaluate the chances of β-amyloid’s role in pathogenesis of retinal neurodegenerative disorder called glaucoma, in silico. …”
    Get full text
    Article
  12. 472

    Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

    Published 2022-01-01
    “…Additionally, some genes involved in signal regulation or encoding hemicellulose- and cellulose-degrading enzymes and extracellular proteases were commonly upregulated during pathogenesis. Overall, we present some putative key genes and processes that may be crucial for S. lycopersici pathogenesis. …”
    Get full text
    Article
  13. 473

    A Relationship between Epithelial Maturation, Bronchopulmonary Dysplasia, and Chronic Obstructive Pulmonary Disease by Abraham B. Roos, Tove Berg, Magnus Nord

    Published 2012-01-01
    “…Recent evidence suggests that defective transcriptional regulation of epithelial differentiation and maturation may contribute to BPD pathogenesis as well as early onset of COPD. The transcriptional regulators CCAAT/enhancer-binding protein (C/EBP)α and C/EBPβ, SMAD family member (Smad)3, GATA binding protein (GATA)6, and NK2 homeobox (NKX)2-1 are reported to be involved in processes contributing to pathogenesis of both BPD and COPD. …”
    Get full text
    Article
  14. 474

    Intrathecal Immunoglobulin A Synthesis in Multiple Sclerosis: From Biological Aspects to Clinical Relevance by Dariia Kliushnikova, Ferdinand Otto, Georg Pilz, Peter Wipfler, Andrea Harrer

    Published 2025-01-01
    “…Intrathecal immunoglobulin A (IgA) synthesis in multiple sclerosis (MS) has long earned little attention, despite a potential significance in disease pathogenesis and prognosis. The presence of IgA-positive plasma cells in MS lesions and along damaged axons suggests a role in disease pathogenesis. …”
    Get full text
    Article
  15. 475

    Plasma MicroRNA Expression Profiles in Psoriasis by Shiju Xiao, Xin Liu, Xiaoxu Wang, Hongpeng Lv, Junbo Zhao, Xinwei Guo, Fuyang Xian, Yunrun Ji, Guangzhong Zhang

    Published 2020-01-01
    “…Network analysis revealed pivotal deregulated plasma miRNAs and their relevant target genes and pathways regulating psoriasis pathogenesis. Conclusions. This study analysed the expression of plasma miRNAs and their target pathways, elucidating the pathogenesis of psoriasis; these results may be used to design novel therapeutic strategies and to identify diagnostic biomarkers for psoriasis.…”
    Get full text
    Article
  16. 476

    Lipid-Induced Mechanisms of Metabolic Syndrome by Yulia K. Denisenko, Oxana Yu Kytikova, Tatyana P. Novgorodtseva, Marina V. Antonyuk, Tatyana A. Gvozdenko, Tatyana A. Kantur

    Published 2020-01-01
    “…Insulin resistance (IR) is the crucial cause of the MetS pathogenesis, which develops against the background of abdominal obesity. …”
    Get full text
    Article
  17. 477

    Peran Kemokin dalam Patogenesis Rinitis Alergi by Effy Huriyati, Bestari J Budiman, Ricki Octiza

    Published 2014-05-01
    “…Conclusion: Eotaxin and CCR3 are the major factor in pathogenesis of allergic rhinitis which is involve eosinophil.…”
    Get full text
    Article
  18. 478

    Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve by Ramona Schmitt, Anke Tscheuschler, Philipp Laschinski, Philipp Discher, Jana Fuchs, Fabian A. Kari

    Published 2020-01-01
    “…The pathogenesis of ascending thoracic aortic aneurysm (aTAA) is thought to differ between patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV), and one of the causes is different hemodynamics. …”
    Get full text
    Article
  19. 479
  20. 480

    Role of Neutrophils in Psoriasis by Wen-Ming Wang, Hong-Zhong Jin

    Published 2020-01-01
    “…In this review, we highlight the role of neutrophils in the pathogenesis of psoriasis.…”
    Get full text
    Article