Gcn2 rescues reprogramming in the absence of Hog1/p38 signaling in C. neoformans during thermal stress by David Goich, Amanda L. M. Bloom, Sean R. Duffy, Maritza N. Ventura, John C. Panepinto

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Advances in the study of apathy related to cerebral small vessel disease by Shuo-han Bu, Shuo-han Bu, Xin-zhu Hu, Zhe Su, Li-tao Li, Li-tao Li

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Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis by D. V. Garbuzenko

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The Role of Motility Impairment in the Pathogenesis of Functional Disorders of the Gastrointestinal Tract and Modern Possibilities for Their Treatment (Resolution of an Expert Council and Literature Review) by I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, S. R. Abdulhakov, N. A. Agafonova, V. A. Akhmedov, T. A. Ilchishina, M. G. Ipatova, O. V. Krapivnaya, Yu. A. Kucheryavyi, M. F. Osipenko, O. A. Storonova, G. N. Tarasova, G. Ya. Khismatullina, S. V. Cheryomushkin

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Dysfunction in mitochondrial electron transport chain drives the pathogenesis of pulmonary arterial hypertension: insights from a multi-omics investigation by Xin Zhang, Jieling Li, Minyi Fu, Xijie Geng, Junjie Hu, Ke-Jing Tang, Pan Chen, Jianyong Zou, Xiaoman Liu, Bo Zeng

“…Conclusions Down-regulation of electron transport from cytochrome c to oxygen in mitochondrial ETC and disruption of the citric acid cycle homeostasis may contribute to PAH pathogenesis. 3-phenyllactic acid emerges as a potential novel diagnostic biomarker for PAH. …”
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Genetic Analysis of Cytokine Promoters in Nonhuman Primates: Implications for Th1/Th2 Profile Characteristics and SIV Disease Pathogenesis by Pavel Bostik, Melanie Watkins, Francois Villinger, Aftab A. Ansari

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A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis by Bani Mukhopadhyay, Cheryl Marietta, Pei-Hong Shen, Abdul Oiseni, Faridoddin Mirshahi, Maria Mazzu, Colin Hodgkinson, Eli Winkler, Qiaoping Yuan, Daniel Miranda, George Kunos, Arun J. Sanyal, David Goldman

“…While differences in metabolism, inflammation, signaling, microbiome signatures and genetic variations have been tied to the pathogenesis of AC, the key underlying mechanisms for this interindividual variability, remain to be fully elucidated. …”
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Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery by Cynthia Koziol-White, Eric Gebski, Gaoyaun Cao, Reynold A. Panettieri

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Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion by V. V. Tsukanov, M. F. Osipenko, E. V. Beloborodova, M. A. Livzan, I. B. Khlynov, S. A. Alekseenko, Yu. P. Sivolap, J. L. Tonkikh, A. V. Vasyutin

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Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies by Elisa Ferretti, Vito Pistoia, Anna Corcione

“…The CX3CL1/CX3CR1 axis is involved in the pathogenesis of several inflammatory cancer including various B cell malignancies. …”
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Systematic expression analysis of cysteine‐rich secretory proteins, antigen 5, and pathogenesis‐related 1 protein (CAP) superfamily in Arabidopsis by Megumi Matsuzawa, Takumi Nakayama, Masa H. Sato, Tomoko Hirano

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KLF9-GRK5-HDAC6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis by Xiaonan Zhou, Peng Jiang, Huangqi Tan, Yanfang Wang, Lunhao Bai

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Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease by Edwin A Homan, Ankit Gilani, Alfonso Rubio-Navarro, Maya A Johnson, Odin M Schaepkens, Eric Cortada, Renan Pereira de Lima, Lisa Stoll, James C Lo

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Response to ‘Commentary on the published position statement regarding the pathogenesis of fetal basal ganglia- thalamic hypoxic-ischaemic injury’ (Anthony et al.) by I Bhorat, E Buchmann, K Frank, P Soma-Pillay, E Nicolaou, L Pistorius, I Smuts

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Neovascular age-related macular degeneration: disease pathogenesis and current state of molecular biomarkers predicting treatment response—a scoping review by Nikolaos Dervenis, Eleftherios Agorogiannis, Panagiotis Dervenis

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Retraction: PrPST, a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease. by PLOS ONE Editors

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Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation by Jinru Cui, Heli Li, Cong Hu, Feiyan Zhang, Yunjie Li, Ying Weng, Liping Yang, Yingying Li, Minglan Yao, Hao Li, Xiaoping Luo, Yan Hao

“…Conclusions: HIF1A-related genes CDKN1A, ETS2, LYN, and SLC16A3 are strong diagnostic markers for ASD and the activation of IL-6/JUN/HIF1A pathway in microglia contributes to the pathogenesis of ASD.…”
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A conserved fungal Knr4/Smi1 protein is crucial for maintaining cell wall stress tolerance and host plant pathogenesis. by Erika Kroll, Carlos Bayon, Jason Rudd, Victoria J Armer, Anjana Magaji-Umashankar, Ryan Ames, Martin Urban, Neil A Brown, Kim Hammond-Kosack

“…Overall, this study demonstrates the utility of an integrated network-level analytical approach to pinpoint genes of high interest to pathogenesis and disease control.…”
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Characteristic TARC/CCL17 expression in the salivary gland of IgG4-related disease: potential diagnostic utility and insights into pathogenesis by Nanako Kikuchi, Sae Hatanaka, Terufumi Kubo, Ryuta Kamekura, Masatoshi Kanda, Takuya Kakuki, Takashi Sasaya, Kengo Mita, Hiroki Kobayashi, Hajime Ikai, Kenta Sasaki, Naoki Shijubou, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Tadashi Hasegawa, Akihiro Miyazaki, Hiroki Takahashi, Ken-ichi Takano, Toshihiko Torigoe

“…Immunological abnormalities are suspected to play a role in its pathogenesis, and there is an epidemiological link to allergic conditions and type 2 inflammation. …”
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Correction: Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery by Cynthia Koziol-White, Eric Gebski, Gaoyaun Cao, Reynold A. Panettieri Jr.

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