Amyloid-β and heart failure in Alzheimer’s disease: the new vistas by Hayder M. Al-Kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Sohaib G. Mohammed, Ali I. Al-Gareeb, Ali K. Albuhadily, Retaj A. Dawood, Amer Al Ali, Mohammed H. Abu-Alghayth

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Response to ‘Commentary on the published position statement regarding the pathogenesis of fetal basal ganglia- thalamic hypoxic-ischaemic injury’ (Anthony et al.) by I Bhorat, E Buchmann, K Frank, P Soma-Pillay, E Nicolaou, L Pistorius, I Smuts

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Neovascular age-related macular degeneration: disease pathogenesis and current state of molecular biomarkers predicting treatment response—a scoping review by Nikolaos Dervenis, Eleftherios Agorogiannis, Panagiotis Dervenis

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Characteristic TARC/CCL17 expression in the salivary gland of IgG4-related disease: potential diagnostic utility and insights into pathogenesis by Nanako Kikuchi, Sae Hatanaka, Terufumi Kubo, Ryuta Kamekura, Masatoshi Kanda, Takuya Kakuki, Takashi Sasaya, Kengo Mita, Hiroki Kobayashi, Hajime Ikai, Kenta Sasaki, Naoki Shijubou, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Tadashi Hasegawa, Akihiro Miyazaki, Hiroki Takahashi, Ken-ichi Takano, Toshihiko Torigoe

“…Immunological abnormalities are suspected to play a role in its pathogenesis, and there is an epidemiological link to allergic conditions and type 2 inflammation. …”
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Correction: Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery by Cynthia Koziol-White, Eric Gebski, Gaoyaun Cao, Reynold A. Panettieri Jr.

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Effects of Somatic Mutations Are Associated with SNP in the Progression of Individual Acute Myeloid Leukemia Patient: The Two-Hit Theory Explains Inherited Predisposition to Pathogenesis by Soyoung Park, Youngil Koh, Sung-Soo Yoon

“…This study evaluated the effects of somatic mutations and single nucleotide polymorphisms (SNPs) on disease progression and tried to verify the two-hit theory in cancer pathogenesis. To address this issue, SNP analysis was performed using the UCSC hg19 program in 10 acute myeloid leukemia patients (samples, G1 to G10), and somatic mutations were identified in the same tumor sample using SomaticSniper and VarScan2. …”
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Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Placenta by Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Suzan M. M. Moursi, Najah M. Al-Baqami, Fawziah A. Al-Salmi, Mai S. Attia

“…This study demonstrated the protective effects of apelin administration on the pathogenesis of PE.…”
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In silico comparative genomic analysis unravels a new candidate protein arsenal specifically associated with Fusarium oxysporum f. sp. albedinis pathogenesis by Hafida Ayada, Boutayna Dhioui, Hamid Mazouz, Abdelhay El harrak, Fatima Jaiti, Bouchra Ouhmidou, Mohammed Diouri, Mohieddine Moumni

“…To unravel the genetic characteristics associated with its pathogenesis, the two available genomes of Foa 133 and Foa 9 were compared with 49 genomes of 29 other pathogenic formae speciales belonging to Fusarium oxysporum species complex (FOSC). …”
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Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics by Simin Luo, Yuhong Zhu, Zhanli Guo, Chuan Zheng, Xi Fu, Fengming You, Xueke Li

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Role of the TGF-β cytokine and its gene polymorphisms in asthma etiopathogenesis by Jacek Plichta, Michał Panek

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Level of adaptative stress of the organism and cellular reactivity of patients with acute festering-inflammatory diseases of the kidneys and paranephral tissues by V. Stepan, R. Sydorchuk, A. Iftodiy, N. Stepan, L. Sydorchuk

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The Pathogenic Role of Expanded CD8⁺CD28^null Angiogenic T Cells in ANCA-Associated Vasculitis by Haomiao Shen, Jinlin Miao, Haoyang Sun, Kui Zhang, Renli Liu, Zichao Li, Leyang Zhang, Peiyan Zhang, Jiawei Wang, Bei Zhang, Longyu Chen, Zhaohui Zheng, Ping Zhu

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Gastroesophageal reflux disease (<i>Proceedings of the Seventeenth Russian Gastroenterological Week, October 10–12 2011, Moscow</i>) by I. V. Mayev, G. L. Yurenev, G. A. Busarova

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Deciphering the role of epigenetics in plant pathogen resistance: Strategies for sustainable sugarcane management by Faisal Mehdi, Yuanli Wu, Shuzhen Zhang, Yimei Gan, Zhengying Cao, Shuting Jiang, Limei Zan, Benpeng Yang

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Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options by Ye. A. Poluektova, S. Yu. Kuchumova, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin

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PRV-1b and PRV-3a infection is associated with the same clinical disease in coho salmon (Oncorhynchus kisutch) farmed in Chile: unraveling the pathogenesis of the orthoreoviral cardiomyopathy and hemolytic jaundice (OCHJ) by Marco Rozas-Serri, Ricardo Ildefonso, Andrea Peña, Victoria Jaramillo, Rodolfo Correa, Soraya Barrientos, Ariel Muñoz, Lucerina Maldonado, Estefanía Peñaloza

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Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma. by Anton W Roodnat, Chelsey Doyle, Breedge Callaghan, Karen Lester, Megan Henry, Carl Sheridan, Declan J McKenna, Colin E Willoughby, Sarah D Atkinson

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Normal Human Gingival Epithelial Cells Sense C. parapsilosis by Toll-Like Receptors and Module Its Pathogenesis through Antimicrobial Peptides and Proinflammatory Cytokines by Raouf Bahri, Sèverine Curt, Dalila Saidane-Mosbahi, Mahmoud Rouabhia

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miR-210 in Exosomes Derived from Macrophages under High Glucose Promotes Mouse Diabetic Obesity Pathogenesis by Suppressing NDUFA4 Expression by Feng Tian, Ping Tang, Zhilian Sun, Ruifen Zhang, Danhua Zhu, Junying He, Jixing Liao, Qinghua Wan, Jie Shen

“…A large number of miRNAs were identified in exosomes derived from adipose tissue macrophages associated with T2DM pathogenesis, but its pathogenic roles remain unknown. …”
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Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

“…This study employs single-cell RNA sequencing (scRNA-seq) and machine learning to explore the the pathogenesis of T2D, with a particular focus on immune cell infiltration.MethodsWe analyzed scRNA-seq data from islet cells of T2D and nondiabetic (ND) patients, identifying differentially expressed genes (DEGs), especially those related to metal ion transport (RMITRGs). …”
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