Showing 2,581 - 2,600 results of 2,971 for search '"pathogenesis"', query time: 0.06s Refine Results
  1. 2581
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  3. 2583

    Elevated Cerebrospinal Fluid Neopterin Concentration Is Associated with Disease Severity in Acute Puumala Hantavirus Infection by Timo Hautala, Terhi Partanen, Tarja Sironen, Saara-Mari Rajaniemi, Nina Hautala, Olli Vainio, Olli Vapalahti, Heikki Kauma, Antti Vaheri

    Published 2013-01-01
    “…The infection activates immunological mechanisms that contribute to the pathogenesis and characteristics of the illness. In this study we measured cerebrospinal fluid (CSF) neopterin concentration from 23 acute-phase NE patients. …”
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  4. 2584

    Intestinal microbiota as biomarkers for different colorectal lesions based on colorectal cancer screening participants in community by Gairui Li, Gairui Li, Dan Zhao, Binfa Ouyang, Yinggang Chen, Yashuang Zhao

    Published 2025-02-01
    “…IntroductionThe dysregulation of intestinal microbiota has been implicated in the pathogenesis of colorectal cancer (CRC). However, the utilization of intestinal microbiota for identify the lesions in different procedures in CRC screening populations remains limited.MethodsA total of 529 high-risk individuals who underwent CRC screening were included, comprising 13 advanced adenomas (Aade), 5 CRC, 59 non-advanced adenomas (Nade), 129 colon polyps (Pol), 99 cases of colorectal inflammatory disease (Inf), and 224 normal controls (Nor). 16S rRNA gene sequencing was used to profile the intestinal microbiota communities. …”
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  5. 2585
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    Impact of training dairy farm personnel on milking routine compliance, udder health, and milk quality by Zelmar Rodriguez, Mario Lopez-Benavides, Marianna B. Gentilini, Pamela L. Ruegg

    Published 2025-02-01
    “…The training session was delivered using an active learning approach prioritizing group discussions, and focused on the pathogenesis, identification, and risk factors for mastitis, as well as the rationale and importance of each step in the milking routine. …”
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  7. 2587

    Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells by Gifty A. Mensah, Anastasia Williams, Pooja Khatkar, Yuriy Kim, James Erickson, Alexandra Duverger, Heather Branscome, Kajal Patil, Hafsa Chaudhry, Yuntao Wu, Olaf Kutsch, Fatah Kashanchi

    Published 2025-01-01
    “…Given the relevance of such effects for the immune response, our results implicate exosome-associated kinases as new possible key contributors to HIV-1 pathogenesis that affect bystander cells. These findings may guide new therapeutic avenues to improve the current antiretroviral treatment regimens.…”
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  8. 2588

    Elevated Plasma Level of 8-Hydroxy-2′-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma by Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan

    Published 2020-01-01
    “…The study shows that there is a significant association between elevated plasma 8-OHdG and POAG, supporting the role of systemic oxidative stress-induced DNA damage in POAG pathogenesis. However, with a high rate of false-positivity, plasma 8-OHdG may lack the ability to serve as a potential biomarker in POAG. …”
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  9. 2589

    MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway by Pei Huang, Guangli Yang, Pingping Zhang, Yin Zhu, Yaning Guan, Jian Sun, Qian Li, Yang An, Xiaoqi Shi, Juanjuan Zhao, Chaohong Liu, Zhixu He, Yan Chen, Zuochen Du

    Published 2025-01-01
    “…Abstract The involvement of B lymphocytes in the pathogenesis of rheumatoid arthritis (RA) is well-established, with their early and aberrant activation being a crucial factor. …”
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  10. 2590

    Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

    Published 2025-02-01
    “…Although improving TEX and enhancing effector function are promising strategies for strengthening immunotherapy, their role in the pathogenesis of TNBC remains unclear. This study’s objective was to develop a prognostic model for TNBC based on exhausted CD8+ T-cell (CD8+ Tex)-related differentially expressed genes (DEGs) and to investigate its clinical and immune relevance. …”
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  11. 2591

    Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization by Lu Ding, Bo Chen, Zhou Zhou, Zhaojun Mei, Kan Cao, Xinyu Lu, Wei Chen

    Published 2025-02-01
    “…ER-related signaling pathways and the regulation of DNA damage may play a critical role in the pathogenesis of both diseases.…”
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  12. 2592

    CD40 Gene Polymorphisms Associated with Susceptibility and Coronary Artery Lesions of Kawasaki Disease in the Taiwanese Population by Ho-Chang Kuo, Mei-Chyn Chao, Yu-Wen Hsu, Ying-Chi Lin, Ying-Hsien Huang, Hong-Ren Yu, Ming-Feng Hou, Chi-Di Liang, Kuender D. Yang, Wei-Chiao Chang, Chih-Lu Wang

    Published 2012-01-01
    “…Other studies from Japan suggested the role of CD40L in the pathogenesis of CAL, and this might help explain the excessive number of males affected with KD but cannot be reproduced by Taiwanese population. …”
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  13. 2593

    Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity by Hui Shi, Yingshao Wang, Rong Li, Wen Xing, Feng-Chun Yang, Jie Bai, Yuan Zhou

    Published 2018-01-01
    “…These results suggested that BMSCs may contribute to the pathogenesis of CMML by altering their cytokine secretion, which will shed light on the further investigation to develop novel therapeutic strategies for CMML patients.…”
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  14. 2594

    Regulatory role of S1P and its receptors in sepsis-induced liver injury by Bin Wang, Bin Wang, Xiaoyu Wu, Xiaoyu Wu, Jiangfeng Cheng, Jiangfeng Cheng, Junming Ye, Junming Ye, Hongquan Zhu, Hongquan Zhu, Xiaofeng Liu, Xiaofeng Liu

    Published 2025-01-01
    “…By elucidating the role of S1P and its receptor in the pathogenesis of sepsis liver injury, this review established a molecular targeting framework, providing novel insights into clinical and drug development.…”
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  15. 2595

    NF-κB Signaling in the Brain of Autistic Subjects by Mazhar Malik, Zujaja Tauqeer, Ashfaq M. Sheikh, Guang Wen, Amenah Nagori, Kun Yang, W. Ted Brown, Xiaohong Li

    Published 2011-01-01
    “…Recent studies suggest that apoptotic and inflammatory mechanisms may contribute to the pathogenesis of this disorder. Nuclear factor-κB (NF-κB) is an important gene transcriptional factor involved in the mediation of inflammation and apoptosis. …”
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  16. 2596

    Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis by Maria J. Gutierrez, Stephen V. Desiderio, Nae-Yuh Wang, Erika Darrah, Laura Cappelli, Gustavo Nino, Michelle Jones, Clifton O. Bingham

    Published 2019-01-01
    “…Further delineating the link between ASC and infection susceptibility in RA may optimize disease management and provide novel insights into disease pathogenesis that are susceptible to intervention.…”
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  17. 2597

    Integrated analysis of genetic, proteinic, and metabolomic alterations in Behcet’s disease by Yanlin Pu, Jing Liang, Yao Wang, Wanyun Zhang, Chuiren Zhou, Ju Shao, Jin Hu, Minghui Chen, Yunjie Shi, Yongdan Mao, Zhijun Chen

    Published 2025-01-01
    “…Collectively, this study showed that the hyperactivity of Th1 and Th17 responses played an essential role in the pathogenesis of BD, and the progression of this disease was associated with enhanced neutrophil chemotaxis, vascular endothelial injury, activation of haemostatic system, and oxidative stress.…”
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  18. 2598

    Pathological and Molecular Characterization of Grass Carp Co-Infected with Two <i>Aeromonas</i> Species by Wenyao Lv, Zhijie Zhou, Lingli Xie, Xinyue Wang, Yifei Zhou, Lang Gui, Xiaoyan Xu, Yubang Shen, Jiale Li, Junqiang Qiu

    Published 2025-01-01
    “…This study investigated the pathogenesis and host immune response in grass carp following concurrent infection with <i>A. hydrophila</i> and <i>A. veronii</i>. …”
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  19. 2599

    Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding by Kyriakos Psarras, Nikolaos Symeonidis, Euthymia Vlachaki, Minas Baltatzis, Georgios Papatolios, Efstathios Pavlidis, Christina Mouratidou, Ioannis Venizelos, Theodoros Pavlidis, Athanasios Sakantamis, Christina Nikolaidou

    Published 2014-01-01
    “…The association of these lesions with chronic inflammation is the most convincing theory for their pathogenesis. For lesions confined to the gallbladder, cholecystectomy is considered to be sufficient, while supplementary chemotherapy significantly improves prognosis in more advanced disease.…”
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  20. 2600

    IL-17 Genetic and Immunophenotypic Evaluation in Chronic Graft-versus-Host Disease by Renata Gonçalves Resende, Jeane de Fátima Correia-Silva, Tarcília Aparecida Silva, Ulisses Eliezer Salomão, Luciano Marques-Silva, Érica Leandro Marciano Vieira, Walderez Ornelas Dutra, Ricardo Santiago Gomez

    Published 2014-01-01
    “…Although interleukin-17 (IL-17) is a recently discovered cytokine associated with several autoimmune diseases, its role in the pathogenesis of chronic graft-versus-host disease (cGVHD) was not established yet. …”
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