Advanced sensing strategies for detecting zinc levels and zinc-related biomarkers in cancer pathogenesis by Daniela Vieira, Graziele Cruzado, Edward Harvey, Geraldine Merle

Get full text

Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris by Rodolfo Pessato Timoteo, Marcos Vinicius da Silva, Camila Botelho Miguel, Djalma Alexandre Alves Silva, Jonatas Da Silva Catarino, Virmondes Rodrigues Junior, Helioswilton Sales-Campos, Carlo Jose Freire Oliveira

Get full text

Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases by Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu

“…Simultaneously, PLD, which also plays an essential role in the pathogenesis of neurodegenerative and neuroimmune diseases. …”
Get full text

From pathogenesis to new developments in treatment of primary progressive multiple sclerosis. Literature review by A. Juknelytė, Ž. Vaičekauskytė, D. Mickevičienė, R. Balnytė

Subjects: Get full text

Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy by Xu Qian, Ji-Qiang Ding, Xin Zhao, Xin-Wen Sheng, Zhao-Rui Wang, Qi-xing Yang, Jing-Jun Zheng, Jia-Gui Zhong, Teng-Yue Zhang, Shu-Qiao He, Wei-Dong Ji, Wei Li, Mei Zhang

“…Temporal lobe epilepsy (TLE) is a chronic neurological disorder that is often resistant to antiepileptic drugs. The pathogenesis of TLE is extremely complicated and remains elusive. …”
Get full text

Adipose tissue may not be a major player in the inflammatory pathogenesis of Autism Spectrum Disorder by Baojiang Wang, Yueyuan Qin, Yong Chen, Xiujie Zheng, Yanjuan Chen, Juan Zhao, Feng Zhang, Shan Duan

“…Conclusions: Our findings suggest that inflammation in ASD likely originates from non-adipocyte sources, implying that adipose tissue may not play a major role in inflammatory pathogenesis of ASD. Consequently, targeting adipose-related inflammation may not be an effective treatment approach, providing new directions for the development of targeted interventions.…”
Get full text

Role of lysosomal enzymes released by alveolar macrophages in the pathogenesis of the acute phase of hypersensitivity pneumonitis by J. L. Pérez-Arellano, M. N. Barrios, T. Martín, M. L. Sánchez, J. M. González Buitrago, A. Jiménez

Get full text

Development and Validation of Chlamydia muridarum Mouse Models for Studying Genital Tract Infection Pathogenesis by Yihui Wang, Zixuan Han, Luying Wang, Xin Sun, Qi Tian, Tianyuan Zhang

Get full text

Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis by D. V. Cherdantsev, O. V. Ovchinnikova, Yu. G. Trofimovich, I. G. Noskov, O. V. Pervova, A. A. Kovalenko

“…Aim: to present literature data on the importance of intra-abdominal hypertension in the pathogenesis of peritonitis.   Key points. Secondary purulent peritonitis is a severe and fairly common form of abdominal infection with high mortality. …”
Get full text

From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis by Sara Ahmadi Badi, Samira Tarashi, Abolfazl Fateh, Pejman Rohani, Andrea Masotti, Seyed Davar Siadat

Get full text

Role of Myokines in Myositis Pathogenesis and Their Potential to be New Therapeutic Targets in Idiopathic Inflammatory Myopathies by Vlad Mageriu, Emilia Manole, Alexandra E. Bastian, Florica Staniceanu

“…Therefore, other signaling pathways that could contribute to the pathogenesis of myositis have been investigated, such as the expression of myokines in skeletal muscle in response to the inflammatory process. …”
Get full text

Is There a Role of 25-Hydroxy Vitamin D in the Pathogenesis of Mild and Moderate-to-Severe Endometriosis? by Nevin Tuten, Serdar Acikgoz, Zahid Mammadov, Eduard Malik, Abdullah Tuten, Onur Guralp

Get full text

Intrahepatic Cholestasis in Non-Alcoholic Fatty Liver Disease: Pathogenesis and Role of Ademetionine in Treatment by Ye. N. Shirokova

“…Aim: to evaluate features of intrahepatic cholestasis (IHC) pathogenesis in non-alcoholic fatty liver disease (NAFLD), as well as role of ademetionine in treatment of this condition.Key statements. …”
Get full text

Microbiome interplays in the gut-liver axis: implications for liver cancer pathogenesis and therapeutic insights by Xuran Wang, Bin Zhang, Runqiu Jiang

Get full text

Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management by Xiaolan Shi, Zijiao Chen, Yi Yang, Su Yan

“…Primarily, making the pathogenesis of BRG clear contributes to a correct and general understanding of this disease for physicians. …”
Get full text

Microbial-Derived Uremic Toxins: Role in the Pathogenesis of Comorbidities in Patients with Chronic Kidney Disease by M. O. Pyatchenkov, A. A. Vlasov, E. V. Sherbakov, S. P. Salikova

“…Аim: to analyze the significance of microbial-derived uremic toxins (MDUT) in the pathogenesis of comorbidities in patients with chronic kidney disease (CKD).Key findings. …”
Get full text

Mitochondrial- and Endoplasmic Reticulum-Associated Oxidative Stress in Alzheimer's Disease: From Pathogenesis to Biomarkers by E. Ferreiro, I. Baldeiras, I. L. Ferreira, R. O. Costa, A. C. Rego, C. F. Pereira, C. R. Oliveira

Get full text

Human-genome single nucleotide polymorphisms affecting transcription factor binding and their role in pathogenesis by E. V. Antontseva, A. O. Degtyareva, E. E. Korbolina, I. S. Damarov, T. I. Merkulova

Get full text

Involvement of Cytokines in the Pathogenesis of Hypersensitivity Pneumonitis: Evaluation of Immunotherapeutic Measures in a Mouse Model by Michel Denis, Marie Bédard, Jacques Gagnon, Yvon Cormier, Michel Laviolette

Get full text

Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same Coin by Michela Guglielmotto, Elena Tamagno, Oliviero Danni

Get full text