Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis by Hua Guo, Jinyang Gao, Liping Gong, Yanqing Wang

“…Colocalization analysis highlighted APOF as a key protein in psoriasis pathogenesis. Validation using skin tissue, EBV-transformed lymphocytes data and inflammation-related protein panels confirmed the associations of RP11-977G19.11 and APOF with psoriasis. …”
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Cardiac achalasia: modern concepts on etiology, pathogenesis, clinical presentation and diagnostics by Yu. V. Yevsyutina, O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…To present up-to-date data on etiology, pathogenesis, clinical presentation and diagnostics of cardiac achalasia.Key points. …”
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Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic by Ziwei Cui, Peng Wang, Weiyue Gao

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Degenerative Cervical Spondylosis: Natural History, Pathogenesis, and Current Management Strategies by Joseph S. Butler, F. Cumhur Öner, Ashley R. Poynton, John M. O'Byrne

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New Insights into Diabetic Kidney Disease: The Potential Pathogenesis and Therapeutic Targets by Wei Jing Liu, Jochen Reiser, Tae Sun Park, Zhangsuo Liu, Shuta Ishibe

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Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Kakali Ghoshal, Maitree Bhattacharyya

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Comprehensive review of Plasmodiophora brassicae: pathogenesis, pathotype diversity, and integrated control methods by Xueliang Xu, Caiyun Wu, Fan Zhang, Jian Yao, Linjuan Fan, Zirong Liu, Yingjuan Yao

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Unraveling the pathogenesis of bone marrow hematopoietic injury and the therapeutic potential of natural products by Jing Long, Hengzhou Lai, Yuqing Huang, Fengming You, Yifang Jiang, Qixuan Kuang

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Can malaria parasite pathogenesis be prevented by treatment with tumor necrosis factor-alpha? by Avner Friedman, Edward M. Lungu

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Autoantibodies and Resident Renal Cells in the Pathogenesis of Lupus Nephritis: Getting to Know the Unknown by Susan Yung, Tak Mao Chan

“…This paper describes the mechanisms through which autoantibodies interact with resident renal cells and how this interaction plays a part in disease pathogenesis that ultimately leads to structural and functional alterations in lupus nephritis.…”
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Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction by Xin Zhang, Yiren Yao, Ying Ding, Wenting Yan, Yang Gu, Xiwen Zhang, Xiaojin Xu

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Aberrant Hepatic Methionine Metabolism and Gene Methylation in the Pathogenesis and Treatment of Alcoholic Steatohepatitis by Charles H. Halsted, Valentina Medici

“…The present paper describes the effects of ethanol on the hepatic methionine cycle, followed by evidence for the central role of reduced SAM in the pathogenesis of ASH according to clinical data and experiments in ethanol-fed animals and in cell models. …”
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Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis by Joshua Kotlyar, Richard D. Granstein

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DNA methylation and its influence on the pathogenesis of osteoarthritis: a systematic literature review by Thomas Nau, Samira Cutts, Nerissa Naidoo

“…Purpose: Evolving evidence demonstrates the role of epigenetics in the pathogenesis of osteoarthritis (OA), whereas in terms of mechanism, DNA methylation has received the highest attention thus far. …”
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Possible Roles of IL-33 in the Innate-Adaptive Immune Crosstalk of Psoriasis Pathogenesis by Serafinella Patrizia Cannavò, Lucrezia Bertino, Eleonora Di Salvo, Valeria Papaianni, Elvira Ventura-Spagnolo, Sebastiano Gangemi

“…IL-33 belongs to the IL-1 family, playing a role in several biologic processes as well as in the pathogenesis of different diseases, including skin pathologies. …”
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The Role of T Cells and Macrophages in Asthma Pathogenesis: A New Perspective on Mutual Crosstalk by Xueyi Zhu, Jie Cui, La Yi, Jingjing Qin, Wuniqiemu Tulake, Fangzhou Teng, Weifeng Tang, Ying Wei, Jingcheng Dong

“…Here, we discuss the role of T cells, macrophages, and their interactions in asthma pathogenesis.…”
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Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy by Sarala Raj Murthi, Andreas Petry, Bachuki Shashikadze, Jan B. Stöckl, Manuel Schmid, Gianluca Santamaria, Karin Klingel, Damir Kračun, Xinpei Chen, Sabine Bauer, Joachim P. Schmitt, Florian Flenkenthaler, Josh Gorham, Christopher N. Toepfer, David Potěšil, Pavel Hruška, Zbyněk Zdráhal, Zsuzsanna Mayer, Mathieu Klop, Luisa Lehmann, Yishi Qin, Laura Papanakli, Nadine Spielmann, Alessandra Moretti, Thomas Fröhlich, Peter Ewert, Stefan Holdenrieder, Jonathan G. Seidman, Christine E. Seidman, Agnes Görlach, Cordula M. Wolf

“…These results demonstrate that HIF signaling is involved in mouse and human HCM pathogenesis. Cardiomyocyte-specific knockout of Hif-1a attenuates disease phenotype in the mouse model. …”
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Functional Dyspepsia and Gastroesophageal Reflux Disease: From Pathogenesis to Current Treatment Strategies by A. S. Trukhmanov, D. E. Rumyantseva

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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…We aimed to investigate the potential role of ChREBP in the pathogenesis of diabetic retinopathy (DR). We used diabetic human and mouse retinal cryosections analyzed by immunohistochemistry. qRT-PCR was performed to quantify gene expression. …”
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A Mechanistic, Stochastic Model Helps Understand Multiple Sclerosis Course and Pathogenesis by Isabella Bordi, Renato Umeton, Vito A. G. Ricigliano, Viviana Annibali, Rosella Mechelli, Giovanni Ristori, Francesca Grassi, Marco Salvetti, Alfonso Sutera

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