Recombinant Factor C as an In Vitro Assay for the Residual Pathogenicity Evaluation of Veterinary Autogenous Vaccines by Antonella Di Paolo, Rosario Liberti, Lucia Anzalone, Claudia Colabella, Andrea Felici, Giulio Severi, Monica Cagiola

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Characterization and Pathogenicity Evaluation of Ceratocystis sp. Isolated from Various Hosts on Acacia crassicarpa Seedlings by Eva Lutfiana, Sri Rahayu, Eko Bhakti Hardiyanto, Sapto Indrioko, Abdul Gafur

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Characterization and pathogenic evaluation of a novel S-INDEL PEDV CH/JSHA2024 isolated in China by Guangli Hu, Qixiang Kang, Zehuan Luo, Rui Geng, Zhiqing Zhao, Ouyang Peng, Chuangchao Zou, Shouhua Feng, Yongchang Cao, Hanqin Shen, Hao Zhang

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Evaluación de patógenos en clones de lulo (Solanum quitoense Lam.) Pathogenity evaluation on Solanum quitoense Lam. Clones by Consuelo Montes Rojas, Luis Armando Muñoz, Víctor Felipe Terán G, Fabio A Prado C, Magally Andrea Quiñónez

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Isolation, Identification, and In Vitro Fungicide Screening of the Pathogen Associated with Pear Dry Blight by Xin Wang, Cai He, Peng Zhang, Lianxin Zhao, Wei Liu, Na Jin, Yanlan Guo

“…This study aimed to identify the causal pathogen, evaluate its pathogenicity, and assess the efficacy of commonly used fungicides. …”
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Antibacterial activity and physicochemical characterization of bioplastic films based on cassava (Manihot esculenta Crantz) starch and rosemary (Salvia rosmarinus) essential oil by Diana Paola Navia Porras, Luis Gabriel Poveda Perdomo, Cuervo Mulet, Jessica Esparza Estrada, Joaquin Hernández Umaña

“…Antibacterial activity was evidenced against the pathogens evaluated except for B. cereus. The films showed average values of Wvt 3.6988 (10-14 g/Pa s m), tensile strength 8.90 MPa, young modulus 1679.72 MPa, and elongation at break 4.33%. …”
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Isolation and identification of Mycoplasma hyorhinis and virulence evaluation of its field isolates by Fan Yang, Fan Yang, Lijun Yang, Lijun Yang, Xuecheng Duan, Xuecheng Duan, Yulin Qian, Yulin Qian, Huifang Ma, Huifang Ma, Xue Jia, Xue Jia, Xinyu Huo, Xinyu Huo, Wenqi Dong, Wenqi Dong, Huanchun Chen, Huanchun Chen, Huanchun Chen, Chen Tan, Chen Tan, Chen Tan

“…It is also linked to the porcine respiratory disease complex (PRDC).MethodsM. hyorhinis prevalence in 2022 Chinese lung samples was assessed by species-specific PCR, followed by isolation and purification of field strains, followed by genetic characterization via multilocus sequence typing (MLST). Pathogenicity evaluation of three isolates (ZZ-1, GD-1 and AH-1) was evaluated using controlled piglet infection trials.ResultsMhr detection in clinical lung samples showed 31.77% prevalence. …”
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Telomerase activity in T-cells as a functional test for pathogenicity assessment of novel genetic variants in telomere biology disorders by Olivia Carlund, Anna Norberg, Pia Osterman, Ida Andersson, Alva Eriksson, Sofie Degerman, Magnus Hultdin

“…In summary, functional analysis of TA in patient-derived cells could support pathogenic evaluation in clinical diagnostics and reduce the number of reported VUS for TBD patients.…”
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Isolation and pathogenicity of the novel porcine reproductive and respiratory syndrome virus 1 strain ZJ01 in South China by Bohua Ren, Ruying Liu, Feibao Huang, Yu Wu, Yu Wu, Xiaopeng Gao, Haishen Zhao, Limiao Lin, Qunhui Li, Qunhui Li, Xiangbin Zhang

“…DiscussionCollectively, this study provides a detailed characterization and pathogenic evaluation of the novel PRRSV-1 strain ZJ01, contributing essential information for the development of effective prevention and control strategies in swine farms.…”
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Susceptibility of periodontal pathogens to a novel target-specific drug delivery system containing self-nanoemulsifying curcumin: An in vitro study by Veena HR, Riya Achamma Daniel, Ashwin Prabhu, Shilpa P, Suman Basavaraju

“…The antibacterial activity of pure nano-curcumin, SNEC, and SNEC in HPMC against the four periodontal pathogens evaluated in terms of MIC was recorded in the range of 0.2‒0.4, 0.4‒0.8, and 0.2‒0.8 µg/mL, respectively. …”
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Identification of novel variants in carbamoyl phosphate synthetase 1 gene and comparative pathogenicity assessments of CPS1 missense variants following ACMG/AMP-ClinGen recommendat... by Fei Li, Qin Cai, Wei Ji, Miao Xu, Guoli Tian, Fanyi Zeng

“…The application of computational tools under the ACMG/AMP-ClinGen criteria revealed an increased sensitivity for pathogenicity evaluation, from variants of uncertain significance (VUS) to likely pathogenic (LP) in previously reported cases; while for variants without clinic information in the ClinVar database, the pathogenicity assessment of VUS remained, and shows a more optimistic and reliable clinical application in molecular diagnosis.…”
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Botryosphaeriaceae Infections on Prunus Germplasm: Evaluation of Pathogenicity, Resistance Loci, and Detached Assays of Southeastern United States Isolates by Daniel Mancero-Castillo, Lisbeth Espinoza, Philip F. Harmon, José X. Chaparro

“…A significant implication of this research is the potential resistance in Prunus germplasm, which was genotyped for the resistance locus Botd8 and evaluated for relative susceptibility to one isolate each from B. dothidea, L. theobromae, and D. seriata. Pathogenicity evaluations of peach, almond, and interspecific hybrids used detached stem and leaf assays for susceptibility to PFG based on lesion lengths and gumming scores. …”
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Novel Loss of Function Variant in SOST From Chinese Family Results in Sclerosteosis 1 by Yufan Guo, Xintao Wu, Yuting Jin, Yu Gu, Yuting Lou, Pu Miao, Ye Wang, Bijun Zhang, Xueting Lin, Chudi Zhang, Jianhua Feng

“…Trio‐whole exome sequencing (Trio‐WES) was performed, and the rare variants (allele frequency < 0.01) in the exon and splicing regions were selected for further pathogenic evaluation. Candidate pathogenic variants were validated through Sanger sequencing. …”
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