Synergistic Enzybiotic Effect of a Bacteriophage Endolysin and an Engineered Glucose Oxidase Against <i>Listeria</i> by David Talens-Perales, José-Antonio Daròs, Julio Polaina, Julia Marín-Navarro

“…Two enzyme-based antimicrobials (enzybiotics) have been combined in a novel treatment against this pathogenic bacterium, resulting in a powerful synergistic effect. …”
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Modeling BK Virus Infection in Renal Transplant Recipients by Nicholas Myers, Dana Droz, Bruce W. Rogers, Hien Tran, Kevin B. Flores, Cliburn Chan, Stuart J. Knechtle, Annette M. Jackson, Xunrong Luo, Eileen T. Chambers, Janice M. McCarthy

“…However, these same medications leave them susceptible to opportunistic infections. One pathogen of particular concern is human polyomavirus 1, also known as BK virus (BKPyV). …”
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The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent by Sebastiaan ter Horst, Aleksandra Siekierska, Ann-Sofie De Meulemeester, Arno Cuvry, Laura Cools, Johan Neyts, Peter de Witte, Joana Rocha-Pereira

“…The Rift Valley fever virus (RVFV) causes haemorrhagic fever, encephalitis, and permanent blindness and has been listed by the WHO as a priority pathogen. To study RVFV pathogenesis and identify small-molecule antivirals, we established a novel In Vivo model using zebrafish larvae. …”
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Maintien du potentiel adaptatif chez les plantes domestiquées à propagation clonale by Doyle McKey, Marianne Elias, Benoît Pujol, Anne Duputié, Marc Delêtre, Delphine Renard

“…However, practiced to the exclusion of sexual reproduction, clonal propagation can lead to erosion of genetic diversity of crop populations, and thus to the loss of the plant’s potential to adapt to stresses such as droughts or the advent of a new pathogen. We have shown that Amerindian cultivators regularly incorporate “volunteer” plants issued from spontaneously produced seedlings into their stocks of clones. …”
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Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis by Lea-Jessica Albrecht, Simone C. Tauber, Julika Merres, Eugenia Kress, Matthias B. Stope, Sandra Jansen, Thomas Pufe, Lars-Ove Brandenburg

“…The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus pneumoniae. …”
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Chromosome-level genome assembly of the sweet potato rot nematode Ditylenchus destructor by Yiwei Yang, Ruirui Feng, Bo Hong, Yuchuan Fang, Chen Liu, Kui Wang, Deliang Peng, Yingmei Li, Huan Peng, Qing Chang

“…Abstract Ditylenchus destructor, commonly known as the potato rot nematode, is a significant plant-parasitic pathogen affecting over 120 plant species globally. …”
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Comparative Genomics of the First and Complete Genome of “Actinobacillus porcitonsillarum” Supports the Novel Species Hypothesis by Valentina Donà, Vincent Perreten

“…“Actinobacillus porcitonsillarum” is considered a nonpathogenic member of the Pasteurellaceae family, which phenotypically resembles the pathogen Actinobacillus pleuropneumoniae. Previous studies suggested that “A. porcitonsillarum” may represent a new species closely related to Actinobacillus minor, yet no full genome has been sequenced so far. …”
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Epidemiology of tularemia in the countries of the WHO Eastern Mediterranean Region (EMRO): A systematic review and meta-analysis. by Mohammad Sholeh, Safoura Moradkasani, Saber Esmaeili

“…<h4>Background</h4>Francisella tularensis, the bacterium that causes tularemia, has been a persistent and widespread pathogen in various regions of the world for centuries. …”
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Alternative disease management strategies for organic apple production in the United Kingdom by Lucas Alexander Shuttleworth

“…However, a warming planet and more unpredictable weather patterns may favour range expansion of pathogens, while increasing plant stress and susceptibility. …”
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Isthmin 1 is Expressed by Progenitor-Like Cells in the Lung: Phenotypical Analysis of Isthmin 1+ Hematopoietic Stem-Like Cells in Homeostasis and during Infection by Guadalupe Rivera-Torruco, Carolina A. Martínez-Mendiola, Tania Angeles-Floriano, Gustavo Alberto Jaimes-Ortega, José Luis Maravillas-Montero, Rodolfo García-Contreras, Yolanda González, Esmeralda Juárez, Porfirio Nava, Vianney Ortiz-Navarrete, Oscar Medina-Contreras, Paula Licona-Limón, Ricardo Valle-Rios

“…The process by which blood cells are generated has been widely studied in homeostasis and during pathogen-triggered inflammatory response. Recently, murine lungs have been shown to be a significant source of hematopoietic progenitors in a process known as extramedullary hematopoiesis. …”
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Long-term storage of C-141 reference strain of melioidosis agent (<i>Burkholderia pseudomallei</i>) by E. A. Artemeva, L. A. Melnikova, A. P. Rodionov

“…Potential possibility of the agent introduction to the Russian Federation as well as the risk of malevolent use of this agent as a tool of bioterrorism dictates the need for storage of this pathogen in the microorganism collections to study its properties, develop and test diagnostic, detection and identification means. …”
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Leptospira and Inflammation by C. F. Gonçalves-de-Albuquerque, P. Burth, A. R. Silva, M. Younes-Ibrahim, H. C. Castro-Faria-Neto, M. V. Castro-Faria

“…This paper will discuss both the role of immunogenic and pathogenic molecules during leptospirosis infection and possible new targets for immunotherapy against leptospira components. …”
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Whole-Genome Sequencing of Mexican Strains of Anaplasma marginale: An Approach to the Causal Agent of Bovine Anaplasmosis by Fernando Martínez-Ocampo, Rosa Estela Quiroz-Castañeda, Itzel Amaro-Estrada, Edgar Dantán-González, Jesús Francisco Preciado de la Torre, Sergio Rodríguez-Camarillo

“…The genomic information contained in the four draft genomes of A. marginale from Mexico will contribute to understanding the molecular landscape of this pathogen.…”
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Leaf spot resistance in sweet and sour cherries by M. S. Lenivtseva, A. P. Kuznetsova, E. E. Radchenko

“…The increasing genetic homogeneity of plant forms used in breeding promotes the acceleration of the pathogen’s adaptive microevolution and the overcoming of previously effective resistance genes. …”
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Positive real-time PCR in pneumococcal meningitis 12 hours after initiation of antibiotic therapy – case report by Cem Thunstedt, Carla Palleis, Johannes Wischmann, Suzette Heck, Konstantinos Dimitriadis, Matthias Klein

“…However, PCR cannot replace cultures when it comes to adapting therapy based on the antibiotic sensitivity of the causative pathogen. Awareness of Austrian syndrome’s diverse manifestations is crucial for timely recognition and appropriate management.…”
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Biofilm in Genital Ecosystem: A Potential Risk Factor for Chlamydia trachomatis Infection by Simone Filardo, Marisa Di Pietro, Giulia Tranquilli, Rosa Sessa

“…Our findings proved, for the first time, that C. trachomatis, an intracellular obligate pathogen, survived, for up to 72 hours after exposure, inside the biofilm produced by C. albicans or G. vaginalis, retaining its infectious properties, as evidenced by the typical chlamydial inclusions observed in the cell monolayer (chlamydial inclusion-forming units at 72 h: 9255 ± 1139 and 9873 ± 1015, respectively). …”
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Clinical diagnosis of Q fever by targeted next-generation sequencing for identification of Coxiella burnetii by Shaohua Zhan, Haoyuan Jin, Hanbing Ji, Xin Hou, Jing Li, Ye Zhang, Jiajia Zheng, Liyan Cui

“…To date, the identification of C. burnetii as the causative pathogen of Q fever using targeted next-generation sequencing (tNGS) has not been previously documented. …”
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Case report: The value of early application of mNGS technology in the diagnosis and treatment of severe Legionnaires’ disease: reports of two cases with different outcomes by Jianqing Fang, Zhe Wang, Yu Shen, Xuenong Wu, Hao Fang, Xiaokui Sun, Ting Yu, Qingqing Zhang

“…The elderly immunocompromised patient died due to a delay in diagnosis.ConclusionThis study highlights the importance of the early recognition and diagnosis of severe Legionnaires’ disease and the advantages of mNGS in identifying the pathogen.…”
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Dataset for comparative analysis of precision metagenomics and traditional methods in urinary tract infection diagnosticsNCBI by Rob E. Carpenter, Sadia Almas, Vaibhav K. Tamrakar, Rahul Sharma

“…By offering insights into both polymicrobial infections and rare pathogens, this dataset supports the advancement of diagnostic strategies for complex and chronic UTIs.…”
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Adaptation and Molecular Characterization of Two Malaysian Very Virulent Infectious Bursal Disease Virus Isolates Adapted in BGM-70 Cell Line by Nafi’u Lawal, Mohd Hair-Bejo, Siti Suri Arshad, Abdul Rahman Omar, Aini Ideris

“…Two Malaysian very virulent infectious bursal disease virus (vvIBDV) strains UPM0081 and UPM190 (also known as UPMB00/81 and UPM04/190, respectively) isolated from local IBD outbreaks were serially passaged 12 times (EP12) in specific pathogen free (SPF) chicken embryonated eggs (CEE) by chorioallantoic membrane (CAM) route. …”
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