LPS from P. gingivalis and Hypoxia Increases Oxidative Stress in Periodontal Ligament Fibroblasts and Contributes to Periodontitis by L. Gölz, S. Memmert, B. Rath-Deschner, A. Jäger, T. Appel, G. Baumgarten, W. Götz, S. Frede

“…Human primary PDL fibroblasts were stimulated with lipopolysaccharide from Porphyromonas gingivalis (LPS-PG), a periodontal pathogen bacterium under normoxic and hypoxic conditions. …”
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Inovirus-Encoded Peptides Induce Specific Toxicity in <i>Pseudomonas aeruginosa</i> by Juehua Weng, Yunxue Guo, Jiayu Gu, Ran Chen, Xiaoxue Wang

“…<i>Pseudomonas aeruginosa</i> is a common opportunistic pathogen associated with nosocomial infections. The primary treatment for infections typically involves antibiotics, which can lead to the emergence of multidrug-resistant strains. …”
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Computational approaches offer a viable alternative for designing antigenic, stable, and safe vaccines to control infections caused by this pathogen. In this study, we employed an immunoinformatic strategy to design a set of candidate multi-epitope subunit vaccines by combining the most potent B and T cell epitopes from three targeted antigenic proteins (BabA, CagA, and VacA). …”
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Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis by Victor E. Reviglio, Ruben H. Sambuelli, Alejandra Olmedo, Micaela Falco, Jose Echenique, Terrence P. O'Brien, Irene C. Kuo

“…By immunohistochemical assays, SLPI was absent in the BSS and control eyes. The causative pathogen was identified in all samples from the endophthalmitis group by traditional culture methods. …”
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Neonatal Sepsis in a Resource-Limited Setting: Causative Microorganisms and Antimicrobial Susceptibility Profile by Edna Nai Acheampong, Joseph Adjei Tsiase, Daniel Kwame Afriyie, Seth Kwabena Amponsah

“…Empiric treatment of suspected neonatal sepsis must be based on data on setting-specific causative pathogens and their respective susceptibilities to antimicrobials, as well as universal treatment guidelines. …”
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In Vitro Control of Phytophthora infestans and Alternaria solani Using Crude Extracts and Essential Oils from Selected Plants by Lydia G. Mugao, Phyllis W. Muturi, Bernard M. Gichimu, Ezekiel K. Njoroge

“…The extracts and essential oils were used to amend the growth media of the test pathogens before introducing the precultured pathogens. …”
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Matrine relieved DHAV-1-induced hepatocyte excessive interferon and pyroptosis by activating mitophagy by Weiran Wang, Xiang Fu, Bolin Gu, Mengxin Hu, Jiaguo Liu

“…Duck hepatitis A virus type 1 (DHAV-1) is a significant pathogen affecting ducklings, capable of causing rapid mortality and adversely impacting the development of the duck industry. …”
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Temperate phage-antibiotic synergy is widespread—extending to Pseudomonas—but varies by phage, host strain, and antibiotic pairing by Rabia Fatima, Alexander P. Hynes

“…Supported by this interaction, here we explore the potential use of combined temperate phage and antibiotic against the multi-drug-resistant pathogen, Pseudomonas aeruginosa. In all, thirty-nine temperate phages were isolated from clinical strains, and a subset was screened for synergy with six antibiotics (ciprofloxacin, levofloxacin, meropenem, piperacillin, tobramycin, and polymyxin B), using checkerboard assays. …”
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Antibiogram Profile of Patients Having Urinary Tract Infection Treated with Most Commonly Used Antibiotics by Bilal Ahmad, Faleesha Gul, Said Hassan, Haseeba Arif, Amber Javaid, Shawkat Ali

“…This study aimed to identify the bacterial pathogens causing UTIs and assess their antimicrobial sensitivity and resistance to commonly used antibiotics. …”
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Survey of Traveler’s Diarrhea: Epidemiology and Testing Reveal the Source by Zhenguo Gao, Muti Mahe, Shabiremu Tuohetamu, Fang Li, Jian Zhang, Yidan Xia, Xiaona Sun, Abuzhalihan Naerkezi, Ruifang Huang, Hongbin Liu, Daxin Ni, Rong Zhang

“…Real-time fluorescent quantitative PCR, bacterial culture, and serological identification methods were used for pathogen detection and identification. Result. There were 7 cases of illness, and the attack rate was 46.67%. …”
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Effects of reproductive technologies and SPF status on some physiological and behavioral characteristics in rats with arterial hypertension (ISIAH strain) by D. S. Ragaeva, T. O. Abramova, I. N. Rozhkova, E. Yu. Brusentsev, E. V. Kalinichenko, T. N. Igonina, S. Ya. Amstislavsky

“…Modern standards of Laboratory Animal Science include working with laboratory animals of high quality, in particular, with specific pathogen free (SPF) mice and rats. On the other hand, assisted reproductive technologies (ART) are widely used in modern medicine for human infertility treatment as well as for genome resource banking. …”
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A case of stroke as a unique sign of subclinical infective endocarditis by Abiotrophia defectiva: a case report by Silvia Puxeddu, Valeria Virdis, Daniele Sacco, Mario Depau, Alessandro M. Atzei, Lorella Pisano, Marcello Di Rosa, Stefania Vacquer, Giorgio Accardi, Emiliano M. Cirio, Aldo Manzin, Cristiana Marinelli, Fabrizio Angius

“…Abstract Purpose Here we describe a patient admitted for a stroke that was unexpectedly correlated with subclinical infective endocarditis attributable to a rarely opportunistic pathogen, Abiotrophia defectiva. Case report A 75-year-old man presented with a stroke. …”
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Molecular Epidemiology of Salmonella enterica in Poultry in South Africa Using the Farm-to-Fork Approach by Melissa A. Ramtahal, Anou M. Somboro, Daniel G. Amoako, Akebe L. K. Abia, Keith Perrett, Linda A. Bester, Sabiha Y. Essack

“…The presence of the zoonotic pathogen Salmonella in the food supply chain poses a serious public health threat. …”
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Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis by Yuling Lin, Jingyu Wang, Fan Bu, Ruyi Zhang, Junhui Wang, Yubing Wang, Mei Huang, Yiyi Huang, Lei Zheng, Qian Wang, Xiumei Hu

“…In this review, we summarize current knowledge on BEVs, with a specific focus on how pathogen-derived BEVs contribute to the promotion of atherosclerosis, as well as how BEVs from gut symbionts and probiotics may mitigate its progression. …”
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Anticancer, Antioxidant, Antimicrobial Activities, and HPLC Analysis of Alcoholic Extracts of Parthenocissus quinquefolia L. Plant Collected from Çanakkale by Sevil Kalın, Ersin Karabacak, Pınar Ilgın, Alper Önder, Özlem Maraba, Ferah Cömert Önder

“…The antifungal activity was determined against Candida albicans as fungal pathogen. The cell apoptosis with methanol extract was obtained between 20 µg/mL and 70 µg/mL for 48 h and 72 h treatments by Hoechst 33258 staining of nuclei under a fluorescence microscopy. …”
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The use of wild-growing Prunus L. species in breeding adaptive dwarf rootstocks of peach by V. G. Eremin

“…Technical efficiency and resistance to pathogens are also important. The work on the creation of such clonal rootstocks of peach is carried out at the Krymsk Experiment Breeding Station (EBS), a branch of VIR, on the basis of the stone fruit crop genetic diversity accumulated at the Station, primarily using the wild species which can serve as donors and sources of important breeding traits. …”
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Exploring the impact of grazing on fecal and soil microbiome dynamics in small ruminants in organic crop-livestock integration systems. by Sejin Cheong, Kimberly Aguirre-Siliezar, Sequoia R Williams, Amélie C M Gaudin, Paulo Pagliari, Michele T Jay-Russell, Roselle Busch, Elizabeth A Maga, Alda F A Pires

“…In integrated crop-livestock systems, livestock graze on cover crops and deposit raw manure onto fields to improve soil health and fertility. However, enteric pathogens shed by grazing animals may be associated with foodborne pathogen contamination of produce influenced by fecal-soil microbial interactions. …”
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Field apple scab susceptibility of a diverse Malus germplasm collection identifies potential sources of resistance for apple breeding by David Papp, Liqiang Gao, Ranjita Thapa, Dan Olmstead, Awais Khan

“…We also screened a differential host set for 2 years to monitor for changes in the effectiveness of ten known scab resistance genes, which allowed us to confirm the presence of virulent pathogen races in the orchard. Results We found that ~ 37% of the wild Malus accessions and domesticated cultivars were resistant to apple scab in the field. …”
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Exploring the feasibility of near-infrared spectroscopy in analyzing and predicting the chemical and biochemical changes of chitin-amended soils by Ken Abamba Omwange, Ana Chen, Renfu Lu, Carly Daiek, Julie Celini, Yan Liu

“… Chitin, a natural polymer, has been added to soil to enhance plant resistance to pathogens, yet its impact on soil’s chemical and biochemical properties remains unclear. …”
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Resistance of barley cultivars approved for use in Russia to harmful organisms and toxic aluminum ions by R. A. Abdullaev, B. A. Batasheva, N. V. Alpatieva, M. A. Chumakov, E. E. Radchenko, O. N. Kovaleva, O. V. Yakovleva

“…The specificity of the host– pathogen interactions necessitates a constant search for new donors of resistance for breeding, and phytosanitary monitoring of cultivars.Materials and methods. …”
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