Advanced approach to primary microsurgical debridement of extensive scleral lacerations involving simultaneous vitrectomy and chorioretinal wound closure by S.S. Shamkin, S.N. Subbotina, A.B. Stepanyants, D.V. Salov

“…A high rate of poor treatment outcomes requires novel approaches to surgical debridement of lacerations given anatomical and pathogenic specifics. </p> <p> <b>Aim</b>: to assess the treatment results of extensive zone 3 scleral laceration surgery by simultaneous vitrectomy and chorioretinal wound debridement. …”
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Antibacterial and Antifungal Activities of Linear and Cyclic Peptides Containing Arginine, Tryptophan, and Diphenylalanine by David Salehi, Eman H. M. Mohammed, Naiera M. Helmy, Keykavous Parang

“…</b> Herein, we report antibacterial and antifungal activities of five linear peptides, namely ((DipR)₄(WR)), ((DipR)₃(WR)₂), ((DipR)₂(WR)₃), ((DipR)(WR)₄), and (DipR)₄R, and five cyclic peptides [(DipR)₄(WR)], [(DipR)₃(WR)₂], [(DipR)₂(WR)₃], [(DipR)(WR)₄], and [DipR]₅, containing alternate positively charged R and hydrophobic W and Dip residues against fungal, Gram-positive, and Gram-negative bacterial pathogens. The minimum inhibitory concentrations (MICs) of all peptides were determined by the micro-broth dilution method against <i>Methicillin-Resistant Staphylococcus aureus</i>, <i>Klebsiella pneumoniae</i>, <i>Pseudomonas aeruginosa</i>, <i>Escherichia coli</i>, <i>Staphylococcus aureus</i>, <i>Enterococcus faecium</i>, <i>Enterococcus faecalis</i>, <i>Streptococcus pneumoniae</i>, and <i>Bacillus subtilis</i>. …”
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Effect of molases addition on survival and growth of tiger shrimp Penaeus monodon Fab. larva treated with SKT-b Vibrio probiotic bacteria by , Widanarni, Wira H Saputra, Dinamella Wahjuningrum

“…   ABSTRACT Probiotic bacteria SKT-b Vibrio that belong to heterotrophic bacteria have been tested can suppress the growth of pathogenic Vibrio harveyi in tiger shrimp larvae. One of the most important energy sources of heterotrophic bacteria is organic carbon such as sucrose and glucose found in molasses. …”
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Adopting Positive Selection Technology and Improving Seed Quality in Smallholder Potato Farmers in South-Western Uganda. by Kajura, Tibanyendera Deo

“…Despite the importance of the crop there has been considerable reduction in yield to the current yield of 4.2 tons ha-1 by smallholder farmers which is far short of its potential on-station yields of over 25 t ha-1, mostly due to inadequate supplies of high quality seed that compels farmers to continuously use their own recycled seed with latent infections by bacterial wilt (Ralstonia solanacearum), viruses and other tuber-borne pathogens. To address this, technologies and innovations such as Positive Selection technology have been developed and promoted among smallholders to enable them generate their own clean seed on-farm for increased productivity. …”
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Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis by U. Gomez-Pinedo, J.A. Matías-Guiu, L. Torre-Fuentes, P. Montero-Escribano, L. Hernández-Lorenzo, V. Pytel, P. Maietta, S. Alvarez, I. Sanclemente-Alamán, L. Moreno-Jimenez, D. Ojeda-Hernandez, N. Villar-Gómez, M.S. Benito-Martin, B. Selma-Calvo, L. Vidorreta-Ballesteros, R. Madrid, J. Matías-Guiu

“…We also conducted a functional study to analyze the pathogenic mechanism of variant rs4149584 (-g.6442643C > G, NM_001065.4:c.362 G > A, R92Q) by plasmid transfection into human oligodendroglioma (HOG) cells, which behave like oligodendrocyte lineage cells; protein labeling was used to locate the protein within cells. …”
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Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis by U. Gomez-Pinedo, J.A. Matías-Guiu, L. Torre-Fuentes, P. Montero-Escribano, L. Hernández-Lorenzo, V. Pytel, P. Maietta, S. Alvarez, I. Sanclemente-Alamán, L. Moreno-Jimenez, D. Ojeda-Hernandez, N. Villar-Gómez, M.S. Benito-Martin, B. Selma-Calvo, L. Vidorreta-Ballesteros, R. Madrid, J. Matías-Guiu

“…We also conducted a functional study to analyze the pathogenic mechanism of variant rs4149584 (-g.6442643C > G, NM_001065.4:c.362 G > A, R92Q) by plasmid transfection into human oligodendroglioma (HOG) cells, which behave like oligodendrocyte lineage cells; protein labeling was used to locate the protein within cells. …”
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Hepatitis B Virus in Polish Blood Donors in the Period 2005–2019—Significant Changes in Epidemiology and Demographic Characteristics of Infected Donors by Aneta Kopacz, Dorota Kubicka-Russel, Grzegorz Liszewski, Ewa Sulkowska, Anna Chrzanowska, Paulina Zwolińska, Ewa Noceń, Anna Potępa, Magdalena Łętowska, Piotr Grabarczyk, the Group of Polish Blood Transfusion Centers for Blood Borne Pathogens

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Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report by Mercedes Aguilar-Soto, Julia M. Zuarth-Vázquez, Laura Leyva-Figueroa, Karla Zarco-Ávila, Armando Gamboa-Domínguez, Aldo Eguiluz-Melendez, Laura C. Hernández-Ramírez

“…He had a personal and family history of NF1 and carried the germline pathogenic variant NF1 (NM_001042492.3): c.147C&gt;A, p.Y49*. …”
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Genomic detection of Panton-Valentine Leucocidins encoding genes, virulence factors and distribution of antiseptic resistance determinants among Methicillin-resistant S. aureus iso... by Masoud A. Juma, Tolbert Sonda, Boaz Wadugu, Davis Kuchaka, Mariana Shayo, Petro Paulo, Patrick Kimu, Livin E. Kanje, Melkiory Beti, Marco Van Zwetselaar, Blandina Mmbaga, Happiness Kumburu

“…The fact that some of these virulent strains harbor the LukS-PV and LukF-PV, the pvl encoding genes, highlight the importance of developing effective interventions to combat the spreading of these pathogenic bacterial strains. Certainly, strengthening antimicrobial resistance surveillance and stewardship will ultimately reduce the selection pressure, improve the patient’s treatment outcome and public health in Tanzania.…”
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Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection by Zeyu Liu, Xue Li, Xiaohong Li, Xingyu Yan, Yuan Tian, Yue Zhao, Kexin Liu, Pei Hao, Shuye Zhang, Chao Zhang

“…Residue K2140 not only facilitates receptor recognition, cell attachment, and infection of CVA10 but also contributes to CVA10 pathogenicity in vivo. Notably, residue K2140 is completely conserved in all strains of the KRM1-dependent enteroviruses. …”
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Prevalence and antibiotic resistance patterns of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from chicken droppings on poultry farms in Gondar city, Northwe... by Mitkie Tigabie, Muluneh Assefa, Yalewayker Gashaw, Azanaw Amare, Aklilu Ambachew, Sirak Biset, Feleke Moges

“…Background: Pseudomonas aeruginosa and Acinetobacter baumannii are common nosocomial pathogens in hospital settings. Recently, they have also been found in non-hospital environments, such as poultry farms. …”
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Seaweed extract of Gracilaria verrucosa as an antibacterial and treatment against Vibrio harveyi infection of Litopenaeus vannamei by Mad Rudi, Sukenda Sukenda, Dinamella Wahjuningrum, Wesly Pasaribu, Dendi Hidayatullah

“…ABSTRACT The objectives of this study were to investigate the antibacterial activity of G. verrucosa extract in test inhibitory zone with different concentrations (500, 1000, 1500, and 2000 mg/L) and  to examine G. verrucosa extract with different dosage (0.5, 1.0, 1.5, 2.0 g/kg) in feed on immune responses (total hemocytes count, phagocytic activity, phenoloxidase activity, respiratory burst) and survival rate in the Litopenaeus vannamei against the pathogenic Vibrio harveyi. Pacific white shrimp with an initial body weight of 5.25±0.55 g was reared in the aquarium (60×30×30 cm3) with a density of 10 shrimp/aquarium. …”
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Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19: a systematic review and meta-analysis by Monireh Golpour, Hossein Jalali, Reza Alizadeh-Navaei, Masoumeh Rezaei Talarposhti, Tahoora Mousavi, Ali Asghar Nadi Ghara

“…Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) is a public health problem and may result in co-infection with other pathogens such as influenza virus. This review investigates the co-infection of SARS-CoV-2 and influenza A/B among patients with COVID-19. …”
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Development of a new data management system for the study of the gut microbiome of children who are small for their gestational age by Felix Manske, Magdalena Durda-Masny, Norbert Grundmann, Jan Mazela, Monika Englert-Golon, Marta Szymankiewicz-Bręborowicz, Joanna Ciomborowska-Basheer, Izabela Makałowska, Anita Szwed, Wojciech Makałowski

“…Links to external resources facilitated literature search with regard to the SGA condition and assessments of the potential pathogenicity of taxa. Since different users will have different demands regarding features, data security, and web environments, we provide our implementation of the web interface as a visual example. …”
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Development and Application of Quadruple Luminex xTAG Method for Simultaneous Detection of Japanese Encephalitis Virus, West Nile Virus, Yellow Fever Virus and Zika Virus by Junying SUN, Qiwen WU, Jichu LI, Chunhong LI, Pengju GUO, Yi HUANG, Feifei YIN

“…Then, PCR products were hybridized with magnetic beads with complementary TAG sequences and streptavidin-phycoerythrin, and the fluorescence signals of magnetic beads and phycoerythrin were detected by Luminex 200 instrument to indicate the classification and quantification of the pathogens of the arbovirus samples.【Result】The Luminex xTAG method applied to detect JEV, WNV, YFV and ZIKV was established, and the optimal primer working concentration was 0.5, 0.5, 0.75, 0.5 µmol/L; the established hybridization system and reaction conditions were: 20 μL of magnetic bead working solution, 5 μL of PCR amplification product, and 75 μL of SAPE working buffer solution; the hybridization temperature, hybridization time and pH value were 37 ℃, 30 min, and 8.0, respectively. …”
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Antimicrobial resistance profile of Pseudomonas aeruginosa clinical isolates from healthcare-associated infections in Ethiopia: A systematic review and meta-analysis. by Zelalem Asmare, Melese Abate Reta, Yalewayker Gashaw, Ermias Getachew, Assefa Sisay, Muluken Gashaw, Ephrem Tamrat, Atitegeb Abera Kidie, Wagaw Abebe, Tadesse Misganaw, Agenagnew Ashagre, Zelalem Dejazmach, Getinet Kumie, Marye Nigatie, Sisay Ayana, Abdu Jemal, Solomon Gedfie, Woldeteklehaymanot Kassahun, Mulat Awoke Kassa, Selamyhun Tadesse, Biruk Beletew Abate

“…A comprehensive understanding of the magnitude of AMR, particularly highly public health important pathogens such as P. aeruginosa, is necessary for the management of infections based on local information.…”
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Clinical significance of Helicobacter pylori infection in iron-deficiency anemia: features of comprehensive treatment approach by I. V. Mayev, S. A. Kochetov

“…Aim of investigation. To study pathogenic and clinical role of Helicobacter pylori infection at irondeficiency anemia (IDA). …”
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The potential of Trichoderma sp. as antibacterial and immunostimulant on white shrimp (Litopenaeus vannamei) by Catur A. Pebrianto, . Sukenda, . Widanarni

“…First experiment was conducted to evaluate inhibitory effect of Trichoderma sp. againts Vibrio harveyi, a pathogenic bacteria causing vibriosis disease on shrimp.  …”
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Dietary supplementation with compound microecological preparations: effects on the production performance and gut microbiota of lactating female rabbits and their litters by Chengcheng Zhao, Youhao Li, Hui Wang, Ahamba Ifeanyi Solomon, Shuhui Wang, Xianggui Dong, Bing Song, Zhanjun Ren

“…Although antibiotics can reduce pathogenic bacteria, they also harm beneficial microorganisms and disrupt the normal intestinal microbiota balance. …”
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Conjunctival microbiota variations in a subset of middle-aged and elderly individuals from Beijing, China by Tian-Yao Zhao, Yu-Chen Wang, Ying-Juan Sun, Jun-Yue Wang, Xiao-Dan Jiang, Xue-Min Li, Ai-Hua Deng

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