Corneal endothelial dysfunction: etiology, pathogenesis, and current treatment approaches by S.V. Trufanov, E.P. Salovarova

“…Keratoplasty is an effective, pathogenically-based treatment for these disorders. Previously, penetrating keratoplasty has been the gold standard surgical procedure for corneal endothelial failure. …”
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Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes by Arthur Monjot, Jérémy Rousseau, Lucie Bittner, Cécile Lepère

“…We notably provide several protein families that could serve as keys to understanding host-parasite interactions representing pathogenicity factors (e.g., involved in hijacking host resources, or associated with immune evasion mechanisms). …”
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Assessment of Antimicrobial Use for Companion Animals in South Korea: Developing Defined Daily Doses and Investigating Veterinarians’ Perception of AMR by Sun-Min Kim, Heyong-Seok Kim, Jong-Won Kim, Kyung-Duk Min

“…There are global concerns regarding the transmission of antimicrobial-resistant pathogens from animals to humans. Especially, companion animals are increasingly recognized as a potential source due to their close interactions with people, despite a limited number of reported cases. …”
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Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest. by Luiz F F Guimarães, Bárbara A Rodrigues, Michelle H F Dias, Matheus G Barcelos, Maria F A Nascimento, Sâmick L Moreira-Nascimento, Sofia L Afonso, Barbara G S Abreu, Jaap M Middeldorp, Francis B Ntumngia, John H Adams, Camila Fabbri, Stefanie Lopes, Cor J F Fernandes, Flora S Kano, Luzia H Carvalho

“…<h4>Background</h4>To develop an effective vaccine against Plasmodium vivax, the most widely dispersed human malaria parasite, it is critical to understand how coinfections with other pathogens could impact malaria-specific immune response. …”
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Human health risk from groundwater consumption: A case study in the Apaaso-Tafo Community in the Bono East Region of Ghana by Emmanuel Okyere, Ethel Bentil, Nana Adwoa Kusi-Addai, Lawson Mensah

“…For rural communities where centralised water treatment plants are lacking, groundwater (GW) is often the resource of choice due to its relatively low pathogenic loading and turbidity. However, GW is highly susceptible to contamination from anthropogenic activities. …”
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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

“…In addition, periodic vaccination is necessary for representatives of some professions (scientists studying pathogenic orthopoxviruses, medical personnel, etc.). …”
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Severe subcutaneous infection with Clostridium septicum in a herd of native Icelandic horses by Charlotta Oddsdóttir, Ólöf G. Sigurðardóttir, Vala Friðriksdóttir, Vilhjálmur Svansson, Birkir Þór Bragason, Sigríður Björnsdóttir

“…However, clostridia are well-known pathogens in Icelandic sheep, which have traditionally shared grazing land with horses. …”
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Morphofunctional characteristics of leaves and fruits in Maloideae (Rosaceae): a. Microstructure of surface tissues by T. Kh. Kumachova, A. S. Voronkov, A. V. Babosha, A. S. Ryabchenko

“…The epidermis, which emerged as a device for protecting deeper underlying tissues from drying, subsequently acquired additional functions (participation in gas exchange and transpiration, absorption and isolation of certain substances as well as protection from the penetration of pathogens) and became a multifunctional tissue consisting of several types of cells (basic, stomatal, and trichomes). …”
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Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked to Solanum mauritianum scope: Discovery of antibacterial and anticancer properties by Abraham Goodness Ogofure, Ezekiel Green

“…This study aimed to investigate the diversity, distribution, and bioactivity of crude extracts derived from endophytic bacteria, focusing on their effects against bacterial pathogens of public health relevance and two cancer cell lines. …”
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Assessment of the Impact of Floods to the Local Community in Nyarusiza Sub-County Kisoro District. by Murengezi, Innocent

“…Floods also lead to vector-borne diseases, transmitted through parasites and pathogens such as mosquitoes. As a result, the health of flood, victims deteriorates as this accounted for 25(17%). …”
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Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa by Keneth Iceland, Kasozi, Zirintunda, Gerald, Ssempijja, Fred, Buyinza, Bridget, Alzahrani, Khalid J., Matama, Kevin, Nakimbugwe, Helen N., Alkazmi, Luay, Onanyang, David, Bogere, Paul, Ochieng, Juma John, Islam, Saher, Matovu, Wycliff, Nalumenya, David Paul, Batiha, Gaber El-Saber, Osuwat, Lawrence Obado, Abdelhamid, Mahmoud, Shen, Tianren, Omadang, Leonard, Welburn, Susan Christina

“…Major Trypanosoma spp. include Trypanosoma brucei rhodesiense Trypanosoma brucei gambiense, and Trypanosoma cruzi, pathogenic for humans, and Trypanosoma vivax, Trypanosoma congolense, Trypanosoma evansi, Trypanosoma brucei brucei, Trypanosoma dionisii, Trypanosoma thomasbancrofti, Trypanosma elephantis, Trypanosoma vegrandis, Trypanosoma copemani, Trypanosoma irwini, Trypanosoma copemani, Trypanosoma gilletti, Trypanosoma theileri, Trypanosoma godfreyi, Trypansoma simiae, and Trypanosoma (Megatrypanum) pestanai. …”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…The antibacterial effects of all synthesized nanomaterials were done according to CLSI against four infamous pathogens. Also, the cytotoxic effects of the synthesized compounds on the human liver cancer cell line (Hep-G2) were assessed by MTT assay. …”
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Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…It partially reversed stroke-induced intestinal barrier disruption and leakage, inflammation, dyslipidemia and oxidative stress, as well as the stroke-induced increase in pathogenic gut microbiota (e.g., Escherichia-Shigella, Enterococcus, Clostridium_innocuum_group) and decrease in beneficial microbiota (e.g., Lachnospiraceae, unclassified__f__Lachnospiracea and Ruminococcus_torques_group). …”
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Investigating the effect of 1,25 dihydroxycholecalciferol-glycosides and phytogenic antioxidants against bacterial chondronecrosis induced by aerosol transmission model by Khawla Alharbi, Andi Asnayanti, Amer Hasan, Wesley J. Vaught, Kathrin Buehler, Jan Dirk Van der Klis, Javier Gonzalez, Michael T. Kidd, Adnan Alrubaye

“…BCO lameness is caused by a bacterial infection in leg bones. Pathogens enter the bloodstream via respiratory and intestinal epithelial translocation and infect the tibia and femoral heads of the birds. …”
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High Frequency of AIFM1 Variants and Phenotype Progression of Auditory Neuropathy in a Chinese Population by Hongyang Wang, Dan Bing, Jin Li, Linyi Xie, Fen Xiong, Lan Lan, Dayong Wang, Jing Guan, Qiuju Wang

“…To decipher the genotype-phenotype correlation of auditory neuropathy (AN) caused by AIFM1 variations, as well as the phenotype progression of these patients, exploring the potential molecular pathogenic mechanism of AN. A total of 36 families of individuals with AN (50 cases) with AIFM1 variations were recruited and identified by Sanger sequencing or next-generation sequencing; the participants included 30 patients from 16 reported families and 20 new cases. …”
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Catheter‐Related Bloodstream Infections Among Hemodialysis Patients in Northern Tanzania: Insights From a Single‐Centre Retrospective Study by Andrea R. Costantine, Sarah J. Urasa, Abid M. Sadiq, Elichilia R. Shao, Furaha S. Lyamuya, Elieishiupendo M. Niccodem, Eugénie M. Kamabu, Venance P. Maro, Elifuraha W. Mkwizu, Nyasatu G. Chamba, Francis F. Furia, Tumaini E. Mirai, Eliada B. Nziku, Doreen T. Eliah, Ibrahim Ali Ibrahim Muhina, Faryal M. Raza, Modesta P. Mitao, Kajiru G. Kilonzo

“…This study aimed to evaluate the determinants of hemodialysis CRBSI and the appropriate antibiogram for the isolated bacterial pathogens among patients attending the KCMC hemodialysis unit. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

“…Autophagy, a cytosolic structure degradation pathway is involved in the maintenance of cellular homeostasis, degradation of intracellular pathogens and generation of energy for immune responses. …”
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Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota by Delower Hossain, Filippo Biscarini, Valentina Monistero, Paola Cremonesi, Bianca Castiglioni, Anoar Jamai Masroure, Alessandro Marinoni, Sara Fusar Poli, Matteo Mezzetti, Maria Filippa Addis, Valerio Bronzo, Erminio Trevisi, Paolo Moroni

“…Differential abundance analyses identified non-pathogenic genera, such as Acinetobacter, Bacteroides, and Paracoccus, that varied between groups at different timepoints. …”
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LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress by Ying Yi, Min-Yu Wu, Kai-Tian Chen, An-Hai Chen, Lin-Qiu Li, Qin Xiong, Xian-Ren Wang, Wen-Bin Lei, Guan-Xia Xiong, Shu-Bin Fang

“…Oxidative stress-mediated damage to the stria vascularis (SV) is one of the pathogenic mechanisms of NIHL. Recent studies indicate that glycolysis plays a critical role in endothelial cells (ECs)-related diseases. …”
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Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma by A. Y. Tikunov, A. N. Shvalov, V. V. Morozov, I. V. Babkin, G. V. Seledtsova, I. O. Voloshina, I. P. Ivanova, A. V. Bardasheva, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…The third most common in all samples were sequences of the Proteobacteria type, which contains pathogenic and opportunistic bacteria. Sequences of the Actinobacteria type were, on average, the fourth most common. …”
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