Endophytic strategies decoded by genome and transcriptome analysis of Fusarium nematophilum strain NQ8GII4 by Siyuan Yan, Qingchen Zhang, Shuxin Jia, Miaomiao Guo, Qiangqiang Zhang, Peiwen Gu, Peiwen Gu

“…However, the molecular mechanisms underlying the symbiotic relationship between NQ8GII4 and alfalfa roots remain poorly understood.MethodsIn this study, we conducted (1) a comparative genomic analysis of selected saprophytic, pathogenic, and endophytic fungi, including molecular phylogeny analysis, whole-genome alignment, and divergence date estimation positioning, and (2) transcriptomic profiling of alfalfa roots infected with NQ8GII4.ResultsOur findings reveal that NQ8GII4 is genetically closely related to F. solani, suggesting it diverged from Fusarium phytopathogens. …”
Get full text

The combined manifestations of dramatically sore throat, congested and edematous mucosa, no-swelling tonsil are specific in acute Omicron pharyngitis by Lei Zhou, Lineng Zhang, Feng Xu

“…Results A total of 39 sore throat patients were included in the study, including 15 confirmed cases of Omicron pharyngitis through nuclear acid or Sars-Cov-2 virus antigen testing, and 24 cases of common pharyngitis caused by other pathogens. Mucosal congestion and edema were identified as the most significant symptoms and consolidated into a single working group. …”
Get full text

Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China by Chen L, Liu R, Ye H, Qian J, Lou D

“…Our findings highlight the emergence of NDM-5-producing K. quasipneumoniae of clinical origin and reinforce the need for vigilant surveillance and infection control measures to curb the proliferation of these highly resistant pathogens.Keywords: blaNDM-5, Klebsiella spp., carbapenem-resistant, whole-genome sequencing…”
Get full text

CHARACTERISTICS OF ANOPHELES BREEDING PLACES IN DAHIAN TAMBUK VILLAGE, GUNUNG MAS DISTRICT, CENTRAL KALIMANTAN by Mouldy Tasya Zahrawana, Dian Mutiasari, Arini Ratnasari, Arif Rahman Jabal, Nopta Triawan, M. Yusuf Ilham Kurniawan, Marchelia Djajanto, Mila Karmila

Get full text

Analysis of risk factors for surgical site infection in spinal surgery patients and study of direct economic losses by Qiuxia Zuo, Kexin Zhao, Baoji Dong, Yuan Zhou, Xiao Wang, Adila Maimaiti, Ping Tian

“…The aim of the study was to explore the types and quantities of pathogenic bacteria involved, the incidence of SSI, and to identify the independent risk factors and direct economic impact on patients with postoperative SSI in spine surgery. …”
Get full text

Ecological analysis of the fish trematode fauna of the Lower Kura by Y.V. Shakaraliyeva

“…Among all the noted trematodes, 7 species are pathogens of fish diseases and 1 species is dangerous to human.…”
Get full text

New methods of local medical treatment of purulent wounds by A. Yu. Grigoryan, A. I. Bezhin, T. A. Pankrusheva, L. V. Zhilyaeva

“…Research methods: in an in vitro experiment, growth retardation zones were determined for the most common pathogens of wound infection using the standard disc method. …”
Get full text

Case report: Trauma-induced Klebsiella pneumoniae invasive syndrome presenting with liver abscess, lung abscess, endophthalmitis, and purulent meningitis by Hong-qiao Chen, Zhen-hua Mo, Wu-xiao Wei

“…Trauma may facilitate invasive infections by disrupting immune barriers and compromising local tissue integrity, creating entry points for pathogens.Case presentationThis study reports a case of a 72-year-old male who developed multiple infections, including liver abscess, lung abscess, left endophthalmitis, and purulent meningitis, following a traumatic fall. …”
Get full text

Avian influenza overview September–December 2024 by European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Leonidas Alexakis, Hubert Buczkowski, Mariette Ducatez, Alice Fusaro, Jose L. Gonzales, Thijs Kuiken, Karl Ståhl, Christoph Staubach, Olov Svartström, Calogero Terregino, Katriina Willgert, Miguel Melo, Lisa Kohnle

“…Abstract Between 21 September and 6 December 2024, 657 highly pathogenic avian influenza (HPAI) A(H5N1) and A(H5N5) virus detections were reported in domestic (341) and wild (316) birds across 27 countries in Europe. …”
Get full text

Patterns of Antibiotic Resistance in Enterobacteriaceae Isolates from Broiler Chicken in the West Region of Cameroon: A Cross-Sectional Study by Jude Fonbah Leinyuy, Innocent Mbulli Ali, Ousenu Karimo, Christopher B. Tume

“…The emergence of multidrug-resistant food-borne pathogens of animal origin including Enterobacteriaceae is a growing concern. …”
Get full text

Antimicrobial and Antibiofilm Activity of Monolaurin against Methicillin-Resistant Staphylococcus aureus Isolated from Wound Infections by Shimaa Salah Hassan Abd El-Ghany, Ahmed Farag Azmy, Ahmed Osama EL-Gendy, Rehab Mahmoud Abd El-Baky, Ahmad Mustafa, Mohammed A. S. Abourehab, Mohamed E. El‐Beeh, Reham Ali Ibrahem

“…Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major pathogens associated with life-threatening infections, showing resistance to various antibiotics. …”
Get full text

Stability and microbial community analysis during rotary drum composting of vegetable waste by V. Sudharsan Varma, Ajay S. Kalamdhad

“…Elevated temperatures favored higher degradation of organic matter, thereby stabilizing the compost within proposed time of composting and also destructing the indicator pathogens.…”
Get full text

Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles by Yuqi Song, Fengrui Liang, Weikun Tian, Erin Rayhill, Liping Ye, Xinghan Tian

“…However, MSCs present risks such as immunogenic responses, malignant transformation, and the potential to transmit infectious pathogens due to their intrinsic proliferative and differentiative abilities. …”
Get full text

Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3. by Chrissy H Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M Harding-Esch, Sarah E Burr, David C W Mabey, Robin L Bailey, Matthew J Burton, Martin J Holland

“…Certain genetic constellations of KIR and HLA class I polymorphisms are associated with a number of diseases in which modulation of the innate responses to viral and intracellular bacterial pathogens is central.<h4>Methodology</h4>A sample of 134 Gambian pedigrees selected to contain at least one individual with conjunctival scarring in the F1 generation was used. …”
Get full text

Phenolic Compounds from Ocimum basilicum Revealed as Antibacterial by Experimental and Computational Screening-Based Studies against Oral Infections by Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia

“…This study is aimed to isolate phenolic compounds from O. basilicum leaves with antibacterial activity against oral pathogens by experimental and computational screening studies. …”
Get full text

Molecular Detection and Multidrug Resistance of Shigella spp. Isolated from Wild Waterfowl and Migratory Birds in Bangladesh by Jarna Karmoker, Md. Saiful Islam, Md. Liton Rana, Md. Ashek Ullah, Fahim Haque Neloy, Nahian Muniath Oishy, Pritom Kumar Pramanik, Mahbubul Pratik Siddique, Sukumar Saha, Md. Tanvir Rahman

“…Birds, especially wild waterfowl and migratory birds have the potential to carry antibiotic-resistant bacteria, but their role in the dissemination of these resistant pathogens is still neglected in Bangladesh. To the best of our knowledge, this study was carried out for the first time in Bangladesh to isolate and determine the occurrence of multidrug-resistant (MDR) Shigella spp. from fecal materials of wild waterfowl and migratory birds. …”
Get full text

Assessing Mitigation Strategies to Reduce Potential Exposures to Indoor Particle Release Events by Katie Van Valkinburgh, Ali Mohammadi Nafchi, Ehsan Mousavi, Vincent Blouin, Nigel Kaye, Andrew R. Metcalf

“…Abstract Airborne transmission is a major concern for many infectious pathogens, including the novel coronavirus. Ventilation is the principal engineering method used to control airborne health hazards in buildings. …”
Get full text

Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Alisha Karki Chhetry, Subhila Dhakal, Lalita Chaudhary, Khimdhoj Karki, Ram Bahadur Khadka, Gautam Prasad Chaudhary, Tonking Bastola, Amrit Poudel, Pramod Aryal, Jitendra Pandey

“…Overall, our study showed that the root bark, pericarp, and leaves extract of D. butyracea evinced prominent antibacterial properties against various pathogenic bacterial strains.…”
Get full text

CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. by John T Loffredo, Thomas C Friedrich, Enrique J León, Jason J Stephany, Denise S Rodrigues, Sean P Spencer, Alex T Bean, Dominic R Beal, Benjamin J Burwitz, Richard A Rudersdorf, Lyle T Wallace, Shari M Piaskowski, Gemma E May, John Sidney, Emma Gostick, Nancy A Wilson, David A Price, Esper G Kallas, Helen Piontkivska, Austin L Hughes, Alessandro Sette, David I Watkins

“…<h4>Conclusions</h4>Together, our data suggest that Mamu-B*08-restricted CD8+ T cell responses effectively control replication of pathogenic SIV(mac)239. All seven regions encoding Mamu-B*08-restricted CD8+ T cell epitopes also exhibit amino acid replacements typically seen only in the presence of Mamu-B*08, suggesting that the variation we observe is indeed selected by CD8+ T cell responses. …”
Get full text

A multi-strain human skin microbiome model provides a testbed for disease modeling by Angela L. Maloney, Tyler Crawford, Jordan Hurlbut, Monica Martinez, Thomas J. Mulhern, Elizabeth L. Wiellette, Else M. Vedula, Vidhya Vijayakumar

“…The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. …”
Get full text