The Association Between Periodontitis, Gingivitis, Tooth Loss and Stroke: An Umbrella Study with Meta-Analysis by Jad El Masri, Ahmad Al Malak, Diala El Masri, Maya Ghazi, Silva Al Boussi, Yasmina El Masri, Mohammad Hassoun, Maryam Tlayss, Pascale Salameh, Hassan Hosseini

“…The relation reached favors the suggested role of some inflammatory changes in the pathogenic pathway leading to atherosclerotic changes.…”
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Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion by Xinpeng Liu, Lan Huang, Yang Ye, Haiyi Wang, Min Tang, Fuqiang He, Zijing Xia, Shi Deng, Peng Zhang, Ruiwu Dai, Shufang Liang

“…It is essential to explore key pathogenicity-driven genes/proteins in bacterial infection and antibiotics resistance, which contributes to develop novel therapeutic strategies against S. aureus infections. …”
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Enhanced biocidal efficacy of alcohol based disinfectants with salt additives by Euna Oh, Hyerin Shin, Sumin Han, Soo Jee Do, Younseo Shin, Ji Hee Pi, Youngjin Kim, Dae-Hong Ko, Kyu Hyoung Lee, Hyo-Jick Choi

“…Abstract Surfaces contaminated with pathogens pose a significant risk of disease transmission and infection. …”
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Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells by K. S. Young, G. R. Hancock, E. C. Fink, A. Zigrossi, B. Flowers, D. A. Cooper, V. T. Nguyen, M. C. Martinez, K. S. Mon, M. Bosland, D. R. Zak, A. P. Runde, M. N. Sharifi, I. Kastrati, D. D. L. Minh, S. Kregel, Sean W. Fanning

“…A tyrosine to serine point mutation at position 537 in the ERα ligand binding domain (LBD) is among the most common and most pathogenic alteration in this setting. It enables endocrine therapy resistance by superceding intrinsic structural-energetic gatekeepers of ER hormone-dependence, it enhances metastatic burden by enabling neomorphic ER-dependent transcriptional programs, and it resists SERM and SERD inhibiton by reducing their binding affinities and abilities to antagonize transcriptional coregulator binding. …”
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Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets by Yuanyuan Zhao, Jing Wang, Hao Wang, Yonggang Huang, Ming Qi, Simeng Liao, Peng Bin, Yulong Yin

“…Pathogenic enterotoxigenic Escherichia coli (ETEC) has been considered a major cause of diarrhea which is a serious public health problem in humans and animals. …”
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Bronchoalveolar Lavage Fluid IFN-γ+ Th17 Cells and Regulatory T Cells in Pulmonary Sarcoidosis by Anders Tøndell, Torolf Moen, Magne Børset, Øyvind Salvesen, Anne Dorthea Rø, Malcolm Sue-Chu

“…IFN-γ+ Th17 cells may represent a pathogenic subset of Th17 cells, yet their expression of IFN-γ could be a consequence of a Th1-polarized cytokine milieu. …”
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First Detection of <i>Wolbachia</i> in Namibian Bird Ectoparasites (Acariformes: Syringophilidae) with a Description of New Quill Mite Species by Eliza Glowska-Patyniak, Katarzyna Kaszewska-Gilas, Izabella Laniecka, Julia Olechnowicz, Kamila Ostrowska, Wiktoria Dmuchowska, Brian K. Schmidt, Jan Hubert, Artur Trzebny

“…Quill mites (Acariformes: Syringophilidae) are a group of bird parasites that have recently attracted increasing interest due to the detection of unique phylogenetic lineages of endosymbiotic bacteria and potentially pathogenic taxa. Our study used an unbiased 16S rRNA gene amplicon sequencing approach to examine several populations of Namibian quill mites for the presence of bacteria that could affect their biology. …”
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Response of Pedunculate Oak (<i>Quercus robur</i> L.) to Adverse Environmental Conditions in Genetic and Dendrochronological Studies by Konstantin V. Krutovsky, Anna A. Popova, Igor A. Yakovlev, Yulai A. Yanbaev, Sergey M. Matveev

“…Investigating its responses to stressors such as drought, extreme temperatures, pests, and pathogens provides valuable insights into its capacity to adapt to climate change. …”
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The effects of Fraxini cortex and Andrographis herba on Escherichia coli-induced diarrhea in chicken by Yunying Wang, Zhenwei Sheng, Huicong Li, Xuewen Tan, Yingqiu Liu, Weimin Zhang, Wuren Ma, Lin Ma, Yunpeng Fan

“…Escherichia coli (E. coli) is a type of pathogenic bacteria that often causes diarrhea in poultry. …”
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Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus by A. A. Chesnokova, E. V. Ivanova, V. V. Pronin, O. A. Chupina, V. Yu. Fomenko, M. S. Volkov, V. N. Irza

“…Pathomorphological studies carried out post experimental infection indicate that duck hepatitis virus induces pathogenic effect not only in birds’ digestive organs (the liver, in particular) but also causes degenerative changes in central and peripheral immune organs: in cloacal bursa, thymus and third eyelid gland, that may be manifested as deficiency of B- and T-cell immunity and requires further studies. …”
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Cross-sectional study of personal protective equipment use, training and biosafety preparedness among healthcare workers during the first months of the SARS-CoV-2 pandemic in Brazi... by Kerstin Muner, Julia Kilgour, Tatiana Ometto, Ana Pérola Drulla Brandão, Andrea Pires dos Santos, Ana Marcia Sá Guimarães

“…This chronic unpreparedness to deal with airborne pathogens may have contributed to one of the highest global rates of tuberculosis and COVID-19 among HCWs.…”
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Spray-Induced Gene Silencing (SIGS): Nanocarrier-Mediated dsRNA Delivery Improves RNAi Efficiency in the Management of Lettuce Gray Mold Caused by <i>Botrytis cinerea</i> by Maria Spada, Claudio Pugliesi, Marco Fambrini, Diego Palpacelli, Andrea Caneo, Susanna Pecchia

“…The plant pathogenic fungus <i>Botrytis cinerea</i> causes significant losses in agricultural production and it is rather difficult to control due to its broad host range and environmental persistence. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…The specific regions of FH targeted by FHAAs correlate with the pathogenic mechanism of the associated disease. In aHUS, FHAAs target the C-terminus, thereby impacting FH ability to recognize cell surfaces. …”
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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

“…Since D11 reduces the acquisition of pathogenic features induced by CD36 ligands, it could support the generation of therapeutic proteins targeting CD36.…”
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Immune status improvement in piglets through the use of interferon-containing products during specific prevention of porcine pleuropneumonia by A. G. Shakhov, L. Yu. Sashnina, V. A. Prokulevich, Yu. Yu. Vladimirova, M. I. Adodina

“…It was found that the use of biferon-S and prostimul together with the vaccine administration is accompanied by immune status improvement in the animals, which is manifested as an increase, in comparison with vaccinated animals that received no interferon-containing products (base case), in serum levels of γ-globulins – by 34.6 and 53.7% (in case of prostimul and β-globulins – by 10.1%), total immunoglobulins – by 32.8 and 37.8%, large circulating immune complexes – by 37.5 and 52.6%, a less significant increase in the levels of small complexes and, as a result, pathogenicity coefficient reduction by 5.4 and 12.4%, respectively. …”
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A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Dia... by Hidetoshi Akimoto, Emi Fukuda-Kawaguchi, Omar Duramad, Yasuyuki Ishii, Kazunari Tanabe

“…These data indicate that the migration of insulin B-peptide-specific Tregs to islet of NOD mice that are involved in the suppression of pathogenic T cells related to diabetes onset and progression could be enhanced by the administration of liposomes containing α-GalCer and insulin B peptide.…”
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Regional patterns and climatic predictors of viruses in honey bee (Apis mellifera) colonies over time by Alison McAfee, Niloofar Alavi-Shoushtari, Renata Labuschagne, Lan Tran, Julia Common, Heather Higo, Stephen F. Pernal, Pierre Giovenazzo, Shelley E. Hoover, Ernesto Guzman-Novoa, Robert W. Currie, Patricia Wolf Veiga, Sarah K. French, Ida M. Conflitti, Mateus Pepinelli, Daniel Borges, Elizabeth M. Walsh, Christine A. Bishop, Amro Zayed, Jason Duffe, M. Marta Guarna, Leonard J. Foster

“…Abstract Honey bee viruses are serious pathogens that can cause poor colony health and productivity. …”
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Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…Additionally, autophagy plays a significant role in combating invasive pathogens, serving as a defensive mechanism against bacteria and viruses. …”
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Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing by Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang

“…Species-level shotgun metagenomic sequencing facilitates the exploration of potentially pathogenic or protective microbes and shed the light of probiotic development in lower respiratory tract.…”
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Can “LITE” Procedure Combined With a Short Course Antibiotic Treatment Be Effective in Treating the Chronic PJI?—A Prospective Randomized Controlled Trial by Yang Chen, Haiqi Ding, Qijin Wang, Zida Huang, Chaofan Zhang, Wenbo Li, Yansheng Lin, Yufeng Guo, Xinyu Fang, Wenming Zhang

“…Patients were randomly assigned to receive either a long course (12 weeks) or short course (2 weeks) of postoperative antibiotics. The pathogens, antibiotics, inflammatory markers, antibiotic‐related complications, cases of reinfection, or re‐operation were recorded. …”
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