Synthesis, in silico and antimicrobial activity study of substituted aromatic imines and their corresponding amines by Hanna Abbo, Darin Edward Holman, Mohamed-Deen Hendricks, Christiana Abimbola Salubi, Marshall Keyster, Salam Titinchi

“…The assessment of antibacterial properties targeted two strains recognized as opportunistic pathogens. Notably, all Schiff base compounds possessing the −C=N moiety exhibited good antibacterial activity against P. aeruginosa and P. agglomerans. …”
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The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil by Rhayra B. Dias, João A. M. Guimarães, Marco B. Cury, Leonardo R. Rocha, Elaine S. da Costa, Liebert P. Nogueira, Camila Hochman-Mendez, Anneliese Fortuna-Costa, Anna Karoline F. Silva, Karin S. Cunha, Sergio A. L. de Souza, Maria Eugênia L. Duarte, Rafaela C. Sartore, Danielle C. Bonfim

“…All final cellular products were free from contamination with aerobic/anaerobic pathogens, mycoplasma, and bacterial endotoxins. The expanded BMSCs expressed CD73, CD90, CD105, and CD146 and were able to differentiate into osteogenic, chondrogenic, and adipogenic lineages in vitro. …”
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Parasites of the genus Nosema, Crithidia and Lotmaria in the honeybee and bumblebee populations: a case study in India by V. Y. Vavilova, I. Konopatskaia, S. L. Luzyanin, M. Woyciechowski, A. G. Blinov

“…The populations of honeybees and bumblebees have been decreasing around the world in the recent decades. A variety of pathogens and parasites, including  bacteria, fungi, protozoa, nematodes, mites and insects play signi ficant role in honeybee and bumblebee colonies loss. …”
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Anti-inflammatory effect of Angiotensin 1-7 in white adipose tissue by Nozomi Nishida, Satoru Sugimoto, Satoshi Miyagaki, Chiharu Cho, Madoka Konishi, Takeshi Goda, Mihoko Yamaguchi, Yasuhiro Kawabe, Hidechika Morimoto, Joji Kusuyama, Takuro Okamura, Masahide Hamaguchi, Jun Mori, Hisakazu Nakajima, Michiaki Fukui, Tomoko Iehara

“…Monocyte chemoattractant protein-1 (MCP-1) produced by white adipocytes and tumour necrosis factor-α (TNF-α) produced by macrophages are pro-inflammatory cytokines and interact to form a pathogenic loop to exacerbate obesity-induced inflammation. …”
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Bacterial diversity impacts as a result of combined sewer overflow in a polluted waterway by O. Calderon, H. Porter-Morgan, J. Jacob, W. Elkins

“…Species found in Newtown Creek include pelagic, marine, human and animal pathogens, hydrocarbonoclastic, and other environmental microbes.…”
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Survey of parasitic fauna data from wild animals through coproparasitological diagnosis in Southern Brazil by Julia Somavilla Lignon, Diego Moscarelli Pinto, Tamires Silva dos Santos, Giulia Ribeiro Meireles, Camila Gonçalves da Silveira, Bianca Conrad Bohm, Felipe Geraldo Pappen, Silvia Gonzalez Monteiro, Mauro Pereira Soares, Raqueli Teresinha França, Fábio Raphael Pascoti Bruhn

“…Conclusions Thus, it was observed that the majority of the animals were parasitized and, consequently, susceptible to a wide range of pathogens of medical and veterinary interest, highlighting the importance of these hosts in the spread of parasites, especially those with zoonotic potential. …”
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Vaginal microbiome distinction in women with HPV+, cervical intraepithelial neoplasia, and cervical cancer, a retrospective study by Yuanyue Li, Yuanyue Li, Xiaomei Wu, Xiaomei Wu

“…IntroductionThe vaginal microbiota is a complex and dynamic micro-ecosystem that plays a pivotal role in protecting the host from various pathogens. Previous studies have investigated the diversity of the vaginal microbiome and its association with health outcomes, particularly the development of HPV-related disorders. …”
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<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis by Marcello Candelli, Marta Sacco Fernandez, Cristina Triunfo, Andrea Piccioni, Veronica Ojetti, Francesco Franceschi, Giulia Pignataro

“…High-risk populations include individuals with underlying conditions such as chronic liver disease, diabetes, or immunosuppression, which heighten susceptibility to severe outcomes. The pathogenicity of <i>V. vulnificus</i> is mediated by an array of virulence factors, including hemolysins, proteases, and capsular polysaccharides, as well as mechanisms facilitating iron acquisition and immune system evasion. …”
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A comparative template-switching cDNA approach for HTS-based multiplex detection of three viruses and one viroid commonly found in apple trees by Francisco Mosquera-Yuqui, Daniel Ramos-Lopez, Xiaojun Hu, Yu Yang, Joshua L. Mendoza, Emmanuel Asare, Joshua Habiger, Oscar P. Hurtado-Gonzales, Andres S. Espindola

“…Abstract Exclusion is a keystone of integrated pest management to prevent the introduction of pathogens. U.S. plant quarantine programs employ PCR and high-throughput sequencing (HTS) to test imported plants for viruses and viroids of concern. …”
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Phylogenetic analysis of dermatophytes isolated from small domestic animals by A. M. Smagulova, E. V. Kukhar, T. I. Glotova, A. G. Glotov

“…The constructed phylogenetic trees reflecting the relationships of dermatophytes showed that, irrespective of the primer pairs used, the Microsporum and Trichophyton pathogens are in all cases reliably assigned to different clades. …”
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Genomic analysis and antibiotic resistance of a multidrug-resistant bacterium isolated from pharmaceutical wastewater treatment plant sludge by Ningyu Sun, Hu Gao, Xinbo Zhang, Zeyou Chen, Anping Peng

“…Additionally, the N4 genome contained 187 genes associated with human disease and 249 virulence factors, underscoring its potential pathogenicity. Overall, this study provides valuable insights into ARBs in PWWTPs and highlights the potential risks posed by multidrug-resistant strains such as N4.…”
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Clinical considerations on antimicrobial resistance potential of complex microbiological samples by Norbert Solymosi, Adrienn Gréta Tóth, Sára Ágnes Nagy, István Csabai, Csongor Feczkó, Tamás Reibling, Tibor Németh

“…This requires knowledge of the AB susceptibility of the pathogens involved in the disease. Therapeutic recommendations based on classical AB susceptibility testing (AST) are based on the analysis of only a fraction of the bacteria present in the disease process. …”
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Molecular assessment of splicing variants in a cohort of patients with inborn errors of immunity: methodological approach and interpretation remarks by Laura Miguel Berenguel, Carla Gianelli, Carla Gianelli, Carla Gianelli, Elisabet Matas Pérez, Teresa del Rosal, Ana Méndez Echevarría, Ángel Robles Marhuenda, Marta Feito Rodríguez, Maria Teresa Caballero Molina, Maria Teresa Caballero Molina, Lorena Magallares García, Brenda Sánchez Garrido, Samantha Hita Díaz, Luis Allende Martínez, Luis Allende Martínez, Pilar Nozal Aranda, Pilar Nozal Aranda, Pilar Nozal Aranda, Carmen Cámara Hijón, Carmen Cámara Hijón, Carmen Cámara Hijón, Eduardo López Granados, Eduardo López Granados, Eduardo López Granados, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, María Bravo García-Morato, María Bravo García-Morato, María Bravo García-Morato

“…Reverse transcription-polymerase chain reaction (RT-PCR) is the molecular assay employed for pathogenicity validation.ResultsWe detected 23 patients of 20 pedigrees with splicing variants in IEI genes, which constitutes the 12.3% of our cohort. …”
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Invasive mosquito species Aedes albopictus and Aedes aegypti on the Black Sea coast of the Caucasus: genetics (COI, ITS2), Wolbachia and Dirofilaria infections by E. V. Shaikevich, I. V. Patraman, A. S. Bogacheva, V. М. Rakova, O. Р. Zelya, L. A. Ganushkina

“…Endosymbiotic bacterium Wolbachia pipientis has different effects on their arthropod hosts and can influence the transmission and spread of the pathogens. The objective of the presented study was molecular-genetic identification of the Aedes mosquitoes collected in sampling sites on the Black Sea coast from 2007 to 2017; determination of genetic variability of Ae. aegypti, Ae. albopictus and their symbiotic bacteria Wolbachia; assessment of mosquitoes ability to be infected and to spread parasitic Dirofilaria. …”
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Study of Lophomonas blattarum Infection in Kidney Transplant Patients in Mashhad City, Iran by Zahra Gheisari, Fariba Berenji, Fatemeh Nazemian, Seyed Ali Akbar Shamsian, Lida Jarahi, Mahmoud Parian, Bibi Razieh Hosseini Farash, Ghodratollah Salehi Sangani

“…The results of this study suggest that L. blattarum should be considered as a pathogenic agent in kidney transplant recipients. It is necessary to examine sputum samples in posttransplant pneumonia patients, especially in those resistant to antibacterial therapy.…”
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Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection by Xinyi Shi, Shenghao Hua, Zeyuan Chen, Weiyi Cao, Mengqing Xiao, Wenlong Pei, Zhe Cao, Zhan Zhang, Haibing Yang, Haibing Yang, Xuejun Shao, Yu Xia, Yu Xia

“…Ultra performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-QTOF/MS) and 16S rRNA gene sequencing were employed to analysis the respiratory microbiome and serum metabolic characteristics of 85 patients with IAV infection and age-matched 55 controls with respiratory disease who tested negative for 13 types of respiratory pathogens. The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”
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Development and Optimization of a Nanoparticle-Based Imidacloprid Insecticide for Effective Control of Blattella germanica by Ismael Saba, Amir Amani, Mozhgan Baniardalani, Hamidreza Basseri

“…Blattella germanica threatens human health by producing asthma-inducing allergens, carrying pathogenic/antibiotic-resistant microbes, and contributing to unhealthy indoor environments. …”
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Seasonal activities, morphological characteristics, and veterinary importance of Haemaphysalis mageshimaensis in Ishigaki and Yonaguni, Okinawa, Japan by Satoko Nakao, Thillaiampalam Sivakumar, Yuko Takakuwa, Hajime Suzuki, Keiichiro Ohta, Keiko Nakamura, Osamu Tsuha, Yuzuru Ikehara, Sanae Ikehara, Syota Ohki, Mizue Inumaru, Yukiko Higa, Rika Umemiya-Shirafuji, Naoaki Yokoyama

“…Ticks are of veterinary importance as they transmit various pathogens to animals. In Yaeyama, Okinawa, Japan, Haemaphysalis longicornis became the dominant tick species after the eradication of Rhipicephalus (Boophilus) microplus in the 1990s. …”
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NTHi killing activity is reduced in COPD patients and is associated with a differential microbiome by Vancheswaran Gopalakrishnan, Ben Sparklin, Jung Hwan Kim, Jerome Bouquet, Margaret Kehl, Tara Kenny, Christopher Morehouse, Carolina Caceres, Paul Warrener, Ventzislava A. Hristova, Susan Wilson, Harini Shandilya, Arnita Barnes, Alexey Ruzin, Junmin Wang, Lisa Oberg, Bastian Angermann, Christopher McCrae, Adam Platt, Daniel Muthas, Sonja Hess, Christine Tkaczyk, Bret R. Sellman, Kristoffer Ostridge, Maria G. Belvisi, Tom M. A. Wilkinson, Karl J. Staples, Antonio DiGiandomenico, on behalf of the MICA II Study Group

“…In addition, antigen–antibody titers in sera to COPD pathogens were determined using a multiplex assay. …”
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The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy by Alia KH Mahmoud, Muhammed Ahmed Abd El Moety, Amal Khalifa Ahmed, Samer A. El-Sawy

“…Objectives: is to detect the role of TNF-α as a pathogenic factor in diabetic nephropathy. Patients and methods:: Between January 2022 and June 2022, 50 diabetic study participants sought medical care at the Sohag University Hospital's outpatient diabetes clinic. …”
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