Combinations of TLR Ligands: A Promising Approach in Cancer Immunotherapy by Saskia Stier, Claudia Maletzki, Ulrike Klier, Michael Linnebacher

“…Toll-like receptors (TLRs), a family of pattern recognition receptors recognizing molecules expressed by pathogens, are typically expressed by immune cells. …”
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The curated Lactobacillus acidophilus NCFM genome provides insights into strain specificity and microevolution by Meichen Pan, Sarah O’Flaherty, Ashley Hibberd, Svetlana Gerdes, Wesley Morovic, Rodolphe Barrangou

“…Besides model organisms and pathogens, some attention has been dedicated to industrial bacteria, notably members of the Lactobacillaceae family that are commonly studied and formulated as probiotic bacteria. …”
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Enhancement of the Antibacterial Efficiency of Silver Nanoparticles against Gram-Positive and Gram-Negative Bacteria Using Blue Laser Light by Anes Al-Sharqi, Kasing Apun, Micky Vincent, Devagi Kanakaraju, Lesley Maurice Bilung

“…The results suggested that Ag-NPs in the presence of visible light exhibit strong antibacterial activity which could be used to inactivate harmful and pathogenic microorganisms.…”
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Chronic Benign Tubular Albuminuria From Compound Heterozygous Variants in : A Case Report by Adam Pietrobon, Mark D. Elliott

“…Diagnosis: Genetic testing identified 3 distinct pathogenic variants in CUBN that were confirmed by segregation analysis to be a compound heterozygous mode of inheritance. …”
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Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales by Ann M. Fallon

“…Unlike <i>thyA</i>, <i>thyX</i> lacks a human counterpart and thus provides a potential target for the treatment of infections caused by pathogenic members of the Rickettsiales.…”
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Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy by Claude Mambo Muvunyi, Jean Claude Semuto Ngabonziza, Emmanuel Edwar Siddig, Ayman Ahmed

“…We recommend exploring cost-effective human and/or animal vaccination mechanisms for RVF, integrating AI-powered drones into dis-ease vectors surveillance and control, and the routine implementation of genomics-enhanced xenosurveillance to monitor changes in pathogens and vectors dynamics in order to inform poli-cymaking and guide the control interventions.…”
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Microbial Quality and Production Methods of Traditional Fermented Cheeses in Lebanon by Mabelle Chedid, Houssam Shaib, Lina Jaber, Youmna El Iskandarani, Shady Kamal Hamadeh

“…This study is aimed at evaluating the quality and safety of two traditional fermented dairy products commonly found in Lebanon (Ambarees and Kishk in its dry and wet forms) by detecting foodborne pathogens and indicator microorganisms. Additionally, it seeks to identify the strengths, weaknesses, opportunities, and threats to quality and the production level. …”
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Improvement of Hand Hygiene Practices among the Healthcare Workers in a Neonatal Intensive Care Unit by Abdullahel Amaan, Sanjoy Kumer Dey, Khainoor Zahan

“…Healthcare workers’ (HCWs) hands become progressively colonized with potential pathogens during their patient care and act as a vehicle for transmission of microorganisms to other patients. …”
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Analysis of the inheritance of the marker SCAR-R1A, linked to the <i>Rpf1</i> red stele root rot resistance gene, in strawberry hybrid progeny by A. S. Lyzhin, I. V. Luk’yanchuk

“…Background. Resistance to pathogens is an important breeding trait of a cultivar. …”
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Physicochemical parameters, microbiological quality, and antibacterial activity of honey from the Bucovina region of Romania by Liliana Luca, Daniela Pauliuc, Florin Ursachi, Mircea Oroian

“…The antibacterial activity was examined against the growth of four pathogenic bacterial strains (Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Salmonella enterica serovar Typhimurium ATCC 14028) by the diffusion test in the agar well and by determining the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). …”
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The Bacterial Profile and Antimicrobial Susceptibility Patterns of Urinary Tract Infection Patients at Pawe General Hospital, Northwest Ethiopia by Abayeneh Girma, Aleka Aemiro

“…The purpose of this study was to isolate, characterize, and determine the antimicrobial susceptibility patterns of bacterial pathogens associated with urinary tract infection at Pawe General Hospital in Northwest Ethiopia. …”
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Profiling bacterial communities of irrigation water and leafy green vegetables produced by small-scale farms and sold in informal settlements in South Africa by D. M. Kgoale, J. K. Gokul, S. Duvenage, E. M. Du Plessis, L. Korsten

“…In commercial production systems, leafy green vegetables have increasingly been reported as associated with foodborne pathogens and disease outbreaks. Little is known of the presence of these organisms on leafy green vegetables in the informal unregulated food systems. …”
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Eilat virus isolated from Culex univittatus mosquitoes from the Namibian Zambezi Region influences in vitro superinfection with alpha- and flaviviruses in a virus-species-dependent... by Heiko D Guggemos, Anne Kopp, Katrin Voigt, Matthias Fendt, Selina L Graff, John K E Mfune, Christian Borgemeister, Sandra Junglen

“…The genus Alphavirus harbors arboviruses of great concern, such as the Chikungunya virus and the equine encephalitis viruses. Transmission of pathogenic alphaviruses by mosquitoes could be influenced by insect-specific alphaviruses such as Eilat virus (EILV). …”
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Chemical Composition and Antibacterial and Antioxidant Activities of Stem Bark Essential Oil and Extracts of Solanecio gigas by Mequanint Molla Yitayeh, Amanu Monie Wassihun

“…The aim of this research is to look at the chemical makeup of Solanecio gigas (S. gigas) stem bark essential oil (EO), as well as the effectiveness of EO and extracts (chloroform, ethyl acetate, and methanol) against human pathogenic bacteria and their antioxidant activity. …”
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Molecular study of blaCTX-M profile among uropathogenic Proteus mirabilis isolates by Kadhim Jwad Jamin, Hussein O. M. Al-Dahmosi, Sura Ihsan Abed Jabuk

“…Infection occurs only when the pathogenicity of the bacteria surpasses the host’s regular defensive systems. …”
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Universal receptive system as a novel regulator of transcriptomic activity of Staphylococcus aureus by George Tetz, Kristina Kardava, Maria Vecherkovskaya, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Victor Tetz

“…The results of this study add another line of evidence that the Universal Receptive System plays an important role in cell regulation, including cell responses to the environmental factors of clinically important pathogens, and that nucleic acid-based TezRs are functionally active parts of the extrabiome.…”
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Situational analysis on porcine diseases of priority to pig industry: methods for biosecurity improvement in the Russian Federation holdings by A. S. Oganesyan, M. A. Shibayev, O. N. Petrova, N. Ye. Baskakova, A. K. Karaulov

“…Based on the discussion results, automation and digitalization of all processes in pig industry, generation of genetically modified pigs not susceptible to the most significant pathogens such as African swine fever, classical swine fever, porcine reproductive and respiratory syndrome viruses and their use for production purposes, further research and implementation of integrated technological solutions for feed sanitation have been concluded to be the evolutionarily significant ways for effective pig farming intensification in the Russian Federation.…”
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Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases by Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi

“…Despite being recognized as a water-borne pathogenic virus for a long time, the cellular tropism of norovirus has not yet been clearly explained. …”
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Blocking TNF-α Reduces <i>Leishmania major</i>-Induced Hyperalgesia and Changes the Cytokine Profile in the Paw Skin of BALB/c Mice with a Potential Positive Effect on Parasite Cle... by Muriel Tahtouh Zaatar, Sara Salman, Reem Hoblos, Rabih Roufayel, Ziad Fajloun, Jean-Marc Sabatier, Marc Karam

“…It is widely accepted that INF-γ, TNF-α, and IL-12 usually favor a protective response, while IL-4, IL-5, IL-10, and IL-13 favor a pathogenic one. These and other cytokines also play a major role in <i>Leishmania</i>-induced hyperalgesia via two possible pathways, one involving prostaglandins and the other sympathetic amines as final mediators, preceded by a cascade of cytokines, among which TNF-α seems to play a pivotal role via a still unclear mechanism of action. …”
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Diagnosis and Treatment of Irritable Bowel Syndrome: Clinical Recommendations of the Russian Gastroenterological Association and Association of Coloproctologists of Russia by V. T. Ivashkin, I. V. Maev, Yu. A. Shelygin, E. K. Baranskaya, S. S. Belous, E. A. Belousova, A. G. Beniashvili, S. V. Vasilyev, A. V. Veselov, E. G. Grigoryev, N. V. Kostenko, V. N. Kashnikov, V. F. Kulikovskiy, I. D. Loranskaya, O. S. Lyashenko, E. A. Poluektova, V. G. Rumyantsev, V. M. Timerbulatov, O. Yu. Fomenko, D. A. Khubezov, E. Yu. Chashkova, G. I. Chibisov, M. V. Shapina, A. A. Sheptulin, O. S. Shifrin, A. S. Trukhmanov, O. P. Alekseeva, S. A. Alekseenko, A. Yu. Baranovsky, O. Yu. Zolnikova, N. V. Korochanskaya, S. N. Mammayev, I. B. Khlynov, V. V. Tsukanov

“…Due to challenging differential diagnosis, IBS can be appropriately established per exclusionem, with pre-examination as follows: general and biochemical blood tests; tissue transglutaminase IgA/IgG antibody tests; thyroid hormones test; faecal occult blood test; hydrogen glucose/ lactulose breath test for bacterial overgrowth; stool test for enteric bacterial pathogens and Clostridium difficile A/B toxins; stool calprotectin test; abdominal ultrasound; OGDS, with biopsy as appropriate; colonoscopy with biopsy. …”
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