Cognitive dysfunction in diabetes – the ‘forgotten’ diabetes complication: a narrative review by Åke Sjöholm, Louise Bennet, Peter M. Nilsson

“…Recent years have seen research that has clarified cerebral insulin resistance and defective insulin signaling as examples of pathogenic factors behind this cognitive impairment in diabetes.Method We provide a narrative review of select and contemporary publications with relevance for the interface between diabetes/prediabetes and cognitive function.Results Recently published studies show that physical activity can reverse insulin resistance in the brain as well as cognitive impairment and pathological appetite regulation. …”
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Assessing food safety and hygiene practices in old age homes in Mangaung and Lejweleputswa regions, free state by Tshegofatso Nhabe, Ntsoaki J. Malebo

“…IntroductionPoor food handling, improper cooking, and inadequate storage practices contribute to the spread of harmful pathogens, particularly in vulnerable environments such as old age homes. …”
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Monoclonal Antibodies in Prevention and Early Treatment of COVID-19 in Lung Transplant Recipients: A Systematic Review and Perspective on the Role of Monoclonal Antibodies in the F... by David A. Van Eijndhoven, Robin Vos, Robin Vos, Saskia Bos, Saskia Bos

“…Moreover, mAb therapy appeared safe and could be a viable option against other pathogens, a route that warrants further investigation.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?…”
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Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage by Ying Zheng, Xi Luo, Zailong Qin, Zhiguang Zhou

“…A series of inflammatory cytokines are produced and released to eliminate pathogens. CpG DNA is an immune stimulator recognized by TLR9, subsequently inducing inflammatory responses in macrophages. …”
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Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway by Yue Wang, Tianwei Lan, Qiongyan Zhang, Chi Zhou, Peng Liu

“…Our study offers novel insights into the pathogenic mechanism of osteolytic lesions and implies that targeting CXCL7 may present a new therapeutic avenue for MM.…”
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Kingdom Come by Ballard: The Stricken City by Nicole Terrien

“…Tel un microscope, le roman donne à voir l’espace de la banlieue comme un gigantesque "incubateur" de nouveaux pathogènes, observés à dessein par les pouvoirs politiques qui se croient à l’abri de la contagion. …”
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Study of Component Composition and Antimicrobial Activity of the Ophthalmic Emulsion Based on the Safflower Flowers (Carthamus tinctorius L.) by Zhanar Abuova, Aknur Turgumbayeva, Ardak Jumagaziyeva, Kairolla Rakhimov, Aigul Jussupkaliyeva

“…The tested ophthalmic emulsion drops show the presumed biological activity against conditionally pathogenic bacteria. The results of chromatographic analysis and antimicrobial activity of the tested samples indicate the prospects for their further study for use as anti-infectious (anti-inflammatory) agents in medicine.…”
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Plant expression systems for production of recombinant pharmaceutically important proteins by E. V. Deineko, A. A. Zagorskaya

“…They are free from unwanted components, such as bacterial endotoxins, hyperglycosylated proteins produced by yeast, animal and human pathogens in cell cultures of transgenic animals. In addition, plants are higher eukaryotes, and therefore fullvalue folding and the formation of multimeric protein complexes occur in their cells, as well as a significant portion of post­translational modifications similar to those in mammalian cells. …”
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OVERVIEW OF THE EPIDEMIC SITUATION ON CERTAIN INFECTIOUS ANIMAL DISEASES IN THE RUSSIAN FEDERATION IN 2018 by N. S. Bardina, A. V. Varkentin, A. K. Karaulov

“…The paper presents the results of analysis of epidemic situation on infectious animal diseases subject to compulsory OIE notification: FMD, African swine fever, classical swine fever, lumpy skin disease, sheep and goat pox, and highly pathogenic avian influenza. The paper presents data on the specified diseases situation in the Russian Federation, broken down by Subjects, and also provides a comparative description of the data for 2017 and 2018. …”
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Source attribution of human campylobacteriosis at the point of exposure by combining comparative exposure assessment and subtype comparison based on comparative genomic fingerprint... by André Ravel, Matt Hurst, Nicoleta Petrica, Julie David, Steven K Mutschall, Katarina Pintar, Eduardo N Taboada, Frank Pollari

“…It used isolates from clinical cases and from eight potential exposure sources (chicken, cattle and pig manure, retail chicken, beef, pork and turkey meat, and surface water) collected within a single sentinel site of an integrated surveillance system for enteric pathogens in Canada. Overall, 1518 non-human isolates and 250 isolates from domestically-acquired human cases were subtyped and their subtype profiles analyzed for source attribution using two attribution models modified to include exposure. …”
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Unveiling the intricate interplay: Exploring biological bridges between renal ischemia-reperfusion injury and T cell-mediated immune rejection in kidney transplantation. by Xinyi Xia, Xinrui Fan, Shan Jiang, Yuhan Liao, Yang Sun

“…<h4>Conclusions</h4>The study demonstrates that renal IRI has a potential role in renal TCMR and the pathogenic pathways are potentially inflammation-related.…”
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Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system. by James Angus Chandler, Jenna Morgan Lang, Srijak Bhatnagar, Jonathan A Eisen, Artyom Kopp

“…Drosophila melanogaster is emerging as an important model of non-pathogenic host-microbe interactions. The genetic and experimental tractability of Drosophila has led to significant gains in our understanding of animal-microbial symbiosis. …”
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Major heavy metals and human gut microbiota composition: a systematic review with nutritional approach by Mahsa Rezazadegan, Bita Forootani, Yeganeh Hoveyda, Niloufar Rezazadegan, Reza Amani

“…Abstract Background The human gut microbiota has a critical role in several aspects of host homeostasis, such as immune development, metabolism, nutrition, and defense against pathogens during life. It can be sensitive to xenobiotics including drugs, diet, or even environmental pollutants, especially heavy metals (HMs). …”
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Assessment of avocado grafting practices and propagules quality against minimum certification standards in Tanzania by Nugwa F. Bugudole, Emmanuely Z. Nungula, Newton Kilasi, Yasinta Nzogela

“…In contrast, the grafting point heights in all three regions conformed to the established standards. For pathogenic fungal 37.8% and 33.3% of potting soil samples tested positive for Phytophthora cinnamomi and Fusarium oxysporum, respectively. …”
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Inferring the energy cost of resistance to parasitic infection and its link to a trade-off by Frédéric Douhard, Carole Moreno-Romieux, Andrea B. Doeschl-Wilson

“…Here we investigate immune energy cost induced by infection, and their potential link to a trade-off between host resistance and fat storage that we previously exposed in sheep divergently selected for resistance to a pathogenic helminth. Results To this purpose, we developed a mathematical model of host-parasite interaction featuring individual changes in energy allocation over the course of infection. …”
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Ecological monitoring of landscape technogenic neoplasms by Daria A. Dostovalova, Alexander Z. Glukhov, Nikolay S. Podgorodetsky, Sergey P. Zhukov

“…A visual assessment of the following diagnostic signs of OCD was carried out: crown density, the presence of dead branches on the trunk and the degree of damage to the leaves by toxicants, pathogens and insects (the average area of necrosis, chlorosis and overeating).…”
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Infusion therapy for chronic liver diseases by I. A. Kurkina, M. V. Mayevskaya, I. N. Tikhonov, V. N. Zozulya, V. I. Leschenko

“…To present modern options of comprehensive infusion therapy at various liver diseases, indications and contraindications for application of basic blood substitute groups, and pathogenically justified approaches for their use. Summary. …”
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Embolic risk management in infective endocarditis: predicting the ‘embolic roulette’ by Adela Mihaela Șerban, Diana Pepine, Andreea Inceu, Alexandra Dadarlat, Alexandru Achim

“…Early identification and characterisation of embolic risk factors, including vegetation size, mobility and echogenicity assessed through transthoracic and transoesophageal echocardiography, but also certain pathogens and biomarkers are important for guiding clinical decisions. …”
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Storage life for seeds of perennial grasses for breeding nurseries by N. A. Feoktistova

“…Variations in seed germination rates among the seeds obtained in different years and those harvested within the same year changed with an increase of the storage period duration (V = 3.6–29.8 %), which attested to a greater heterogeneity of the material under study and could be caused by the presence and development of pathogenic microflora on seeds. Promising seed samples for breeding or for storage, with laboratory germination rates from 79 to 50 %, can be sown with an increased seeding rate on certain plots; meanwhile, the estimated maximum practical use for the seeds of awnless bromegrass is up to 3.5 years; for red clover up to 5.5 years; and for changeable alfalfa up to 8.5 years.…”
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Application and Clinical Effectiveness of Antibiotic-Loaded Bone Cement to Promote Soft Tissue Granulation in the Treatment of Neuropathic Diabetic Foot Ulcers Complicated by Osteo... by Regis Ernest Mendame Ehya, Hao Zhang, Baiwen Qi, Aixi Yu

“…Results show that compared with the control group, patients in the study group had significant difference in the number of patients for baseline pathogens eradication, short NRS pain score, hospital length of stay and cost, wound surface reduction, healing time, low rate of complications, and infection recurrence. …”
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