Functional genomic insights into Floricoccus penangensis ML061-4 isolated from leaf surface of Assam tea by Patthanasak Rungsirivanich, Elvina Parlindungan, Jennifer Mahony, Witsanu Supandee, Narumol Thongwai, Douwe van Sinderen

“…The ML061-4 genome was evaluated for genes associated with complex carbohydrate metabolism, bacterial adhesion, virulence factors, pathogenicity, bacteriophages, antiviral defence systems as well as toxin- and antibiotic-resistance associated genes, and genes involved in toxin production, secondary metabolite biosynthesis and xenobiotics biodegradation. …”
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Microcephalic osteodysplastic primordial dwarfism type II in four Indian children with PCNT variants by Amit Singh, Mahak Garg, Mohammed Shariq, Preeti Khetarpal, Inusha Panigrahi

“…Conclusion All four patients had significant microcephaly and growth retardation and the new variants were found to be likely pathogenic by in silico analysis. Early detection of the syndrome is essential for early interventions, proper genetic counseling and prenatal diagnosis.…”
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Molecular Characterization of Methicillin Resistant and Extended Spectrum ?-Lactamase Staphylococcus aureus Isolated from Burn Patients by Shawnm Ahmed Aziz

“…Staphylococcus aureus the most notorious pathogens causes morbidity and mortality especially in burn patients. …”
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Assessment of the Antimicrobial Efficacy and Mechanical Properties of Glass Ionomer Cement (GIC) Incorporating Silver Nanoparticles In Varying Concentrations for Pediatric Dental A... by Md. Imran, Rashmirekha Mallick, Rohit Vadlamani, Antarik Dhar

“…Materials and Methods: This study investigated the effects of integrating varying concentrations of AgNPs into GIC on its antimicrobial efficacy against common oral pathogens and its mechanical properties. Three concentrations of AgNPs (0.5%, 1%, and 1.5% by weight) were evaluated. …”
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Exploring Advances in Natural Plant Molecules for Allergic Rhinitis Immunomodulation in Vivo and in Vitro by Li B, Dong B, Xie L, Li Y

“…Bingquan Li,1,* Boyang Dong,1,* Liangzhen Xie,2 Yan Li2 1Graduate School, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2Ear-Nose-Throat Department, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Liangzhen Xie; Yan Li, Email xieliangzhen888111@163.com; liyan888111@163.comAbstract: Allergic rhinitis (AR) is a prevalent allergic disease that imposes significant economic burdens and life pressures on individuals, families, and society, particularly in the context of accelerating globalization and increasing pathogenic factors. Current clinical therapies for AR include antihistamines, glucocorticoids administered via various routes, leukotriene receptor antagonists, immunotherapy, and several decongestants. …”
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A novel two-component system contributing the catabolism of c-di-GMP influences virulence in Aeromonas veronii by Chaolun Liu, Jia Shao, Xiang Ma, Yanqiong Tang, Juanjuan Li, Hong Li, Xue Chi, Zhu Liu

“…In a murine model, ΔarrS exhibited increased pathogenicity, leading to elevated TNF-α and IFN-γ levels in serum, and severer toxicity to spleen and kidney. …”
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Insights into the roles of exogenous phenylalanine and tyrosine in improving rapamycin production of Streptomyces rapamycinicus with transcriptome analysis by Dongmei Xu, Yaoyao Wang, Hongzhen Li, Bing Wang, Libin Chai, Li Feng, Fengzhi Ren, Xuejin Zhao, Xuexia Zhang

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Evaluation of serum leptin and adiponectin and their associations with obesity-related renal injury among Egyptian adolescents by Azza A El-Shaheed, Reham F. Fahmy, Nermine N. Mahfouz, Salwa R El-Zayat, Hiba Sibaii, Rehab S.I. Moustafa

“…Conclusion Leptin and adiponectin are the main pathogenic factors for renal injury in obese adolescents.…”
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Synbiotics in caries prevention: A scoping review. by Mohammed Nadeem Bijle, Manikandan Ekambaram, Edward C M Lo, Cynthia Kar Yung Yiu

“…Future studies are needed to examine the combination of amino acids (esp. arginine) with probiotics as a potential synbiotic against cariogenic pathogens.…”
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Candiduria in Pediatric Patients: Two Case Reports and a Review of Management Strategies. by Aferdita Ademi, Ferizat Dika Haxhirexha, Agron Dogjani, Kastriot Haxhirexha

“… Introduction: Urinary infections, while common in intensive care and surgical units, present a unique challenge when fungal pathogens are involved. These fungal urinary infections, known as fungiuria, require a more intricate and prolonged treatment plan involving antifungal medications. …”
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Investigating some biological activities of ethanolic extract from Chloranthus japonicus Sieb. leaves by Nguyễn Minh Cần, Nguyễn Thị Mỹ Trinh

“…However, at these concentrations, the extract did not show any inhibitory effect on the growth of some opportunistic pathogens, including S. aureus, P. aerugionsa, E. faecalis, and E. coli; and in vitro immunomodulatory effect on LPS-stimulated Raw 264.7 model. …”
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Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Keratitis by Xin-Yu Pan, Meng Wang, Yi-Dan Xu, Lin-Nong Wang

“…A total of 287 patients with IK admitted to the Department of Ophthalmology of Nanjing First Hospital between August 2018 and December 2022 were analyzed retrospectively, and the pathogenic causes, etiological characteristics, detection, treatment methods, and efficacy were summarized. …”
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MOLECULAR TYPING OF METHICILLIN-SUSCEPTIBLE STAPHYLOCOCCUS AUREUS (MSSA), ISOLATED FROM MONKEYS, BASED ON COAGULASE GENE POLYMORPHISM by V. A. Kalashnikova

“…The lack of information on the genotyping of these pathogens detected in monkeys living in captivity served as a stimulus to conduct a similar research, since staphylococcal infections in the primates are widespread. …”
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Seroprevalence to herpesviruses in patients with primary brain gliomas by T. A. Zykova, O. I. Kit, E. E. Rostorguev, E. A. Shevyakova, N. S. Kuznetsova

“…The absence of statistically significant differences in seropositivity between groups of patients and their presence between pathogens is most likely a reflection of general trends in the population, and the question of the involvement of various representatives of the Herpesviridae family in neuro-oncogenesis of primary glial brain tumors still remains open.…”
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SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject by R. Wumba, M. Mandina, Y. Nlandu, J. R. Makulo, A. Tshimpi, P. Mbala, A. Mbangama, P. Kabututu, J. M. Kayembe

“…Background. The pathogenic mechanisms and immune response of COVID-19 are far from clear. …”
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Application of Genomic Selection in Beef Cattle Disease Prevention by Ramanathan Kasimanickam, Joao Carlos Pinheiro Ferreira, John Kastelic, Vanmathy Kasimanickam

“…By incorporating genomic technologies such as whole-genome sequencing, genotyping, and transcriptomics, researchers can identify specific genetic variants associated with resistance to pathogens like bovine respiratory disease and Johne’s disease. …”
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Dual Control of Host Actin Polymerization by a Legionella Effector Pair by M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

“…Host actin cytoskeleton is often targeted by pathogenic bacteria through the secretion of effectors. …”
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Selective cultivation of bacterial strains with lipolytic and hydrocarbon-oxidizing activity from bottom sediments of the Ob River, Western Siberia by A. I. Gerasimchuk, D. A. Ivasenko, A. A. Kasymova, Yu. A. Frank

“…The phylogenetic and metabolic diversity of the cultivated non-pathogenic bacterial strains with lipolytic and oil-oxidizing activity revealed in the study indicates the biotechnological potential of the isolates. …”
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Notch Signaling Mediates TNF-α-Induced IL-6 Production in Cultured Fibroblast-Like Synoviocytes from Rheumatoid Arthritis by Zhijun Jiao, Wenhong Wang, Jie Ma, Shengjun Wang, Zhaoliang Su, Huaxi Xu

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Ln-MOF in production of durable antimicrobial and UV-Protective fluorescent cotton fabric for potential application in military textiles by Hossam E. Emam, Reda M. Abdelhameed, Osama M. Darwesh, Hanan B. Ahmed

“…Against three different pathogens (Escherichia coli, staphylococcus Aureus and Candida albicans), Ln-MOF@fabrics exhibited good microbial reduction of 68–79% and 81–91% in case of cotton and Q-cotton, respectively. …”
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