Non-Thermal Plasma-Activated Water Enhances Nursery Production of Vegetables: A Species-Specific Study by Silvia Locatelli, Stefano Triolone, Marina De Bonis, Giampaolo Zanin, Carlo Nicoletto

“…This technology has shown potential benefits in boosting seed germination, promoting plant growth, as an effective defense against plant pathogens, and increasing systemic plant resistance. …”
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Kidney and liver histopathology of sea bass Lates calcarifer infected with black body syndrome-associated bacteria by Sri Nuryati, Mauliza Yanti, Rahman, Sutiastuti Wahyuwardani

“…Microscopic anatomical pathology of each bacterium needs to be done to determine its pathogenicity. This study aims to compare the degree of damage to sea bass juveniles' liver and kidney organs through histopathological observations due to bacterial infections that cause BBS. …”
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Source attribution of human Campylobacter infection: a multi-country model in the European Union by Cecilie Thystrup, Maja Lykke Brinch, Clementine Henri, Lapo Mughini-Gras, Lapo Mughini-Gras, Eelco Franz, Kinga Wieczorek, Montserrat Gutierrez, Deirdre M. Prendergast, Geraldine Duffy, Catherine M. Burgess, Declan Bolton, Julio Alvarez, Julio Alvarez, Vicente Lopez-Chavarrias, Thomas Rosendal, Lurdes Clemente, Ana Amaro, Aldert L. Zomer, Katrine Grimstrup Joensen, Eva Møller Nielsen, Gaia Scavia, Magdalena Skarżyńska, Miguel Pinto, Mónica Oleastro, Wonhee Cha, Amandine Thépault, Katell Rivoal, Martine Denis, Marianne Chemaly, Tine Hald

“…National action plans have included source attribution studies as a way to quantify the contribution of specific sources and understand the dynamic of transmission of foodborne pathogens like Salmonella and Campylobacter. Such information is crucial for implementing targeted intervention. …”
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IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

“…IRG1 and its metabolites play important roles in infection, immune-related diseases and tumor progression by exerting resistance of pathogens, attenuating inflammation and producing antioxidant substances through various pathways and mechanisms. …”
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Occurrence of Fungi on Duck Egg Shells and Drug Resistance Analysis of <i>Aspergillus</i> spp. Isolates by Andrzej Gaweł, Magdalena Siedlecka, Magdalena Karwańska, Milena Skrok, Iwona Przychodniak, Piotr Knap, Aleksandra Chmielina, Violetta Truszko, Maciej Kuczkowski, Karolina Bierowiec, Anna Woźniak-Biel, Barbara Szczepankiewicz, Kamila Bobrek

“…Fungi are a typical part of the microbiome of poultry houses, but some of the genera can be pathogenic for poultry and humans. An investigation was conducted on 200 duck eggs from 10 flocks to determine total fungal contamination on the eggshells. …”
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Effect of colchicine on physiological and biochemical properties of <i>Rhodococcus qingshengii</i> by Yu. A. Markova, L. A. Belovezhets, V. N. Nurminsky, I. S. Kapustina, N. V. Ozolina, V. V. Gurina, A. L. Rakevich, A. V. Sidorov

“…Due to their relatively high growth rate and ability to form biof ilms, Rhodococcus are a convenient model for studying the effect of biologically active compounds on pathogenic Mycolata. Colchicine was previously found to reduce biof ilm formation by P. carotovorum VKM B-1247 and R. qingshengii VKM Ac-2784D. …”
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Cyclophilin–CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8 by Gabor Tajti, Laura Gebetsberger, Gregor Pamlitschka, Katharina Aigner-Radakovics, Judith Leitner, Peter Steinberger, Hannes Stockinger, Anna Ohradanova-Repic

“…Monocytes and macrophages, as important constituents of the innate immune system, are equipped with multiple Toll-like-receptors (TLRs) to recognize invading pathogens, such as SARS-CoV-2, and mount an antiviral response. …”
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Case report: Novel ACTN4 variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation by Ignacio Alarcón, Carolina Peralta, Francisco Cammarata-Scalisi, Maykol Araya Castillo, Francisco Cano, Francisco Cano, Angélica Rojo, María Luisa Ceballos, María Luisa Ceballos, Paola Krall, Paola Krall

“…He requested to be considered for kidney transplantation and the VUS in ACTN4 was re-analyzed to assess potential risks, resulting in a reclassification as likely pathogenic (PM1+PM2+PM4 criteria). At 14 years old, he received a deceased donor kidney allograft without recurrence during the subsequent 5 months.ConclusionsIdentifying VUS is a recurring challenge in routine clinical genetics, particularly for patients with rare diseases or atypical phenotypes in underrepresented populations. …”
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Study on the multidrug resistance and transmission factors of Staphylococcus aureus at the ‘animal–environment–human’ interface in the broiler feeding cycle by Fangyuan Hu, Fangyuan Hu, Yaopeng Liu, Yaopeng Liu, Lin Wang, Juan Wang, Na Liu, Yan Li, Xiaoxiao Duan, Junwei Wang, Mingzhe Lu, Junhui Liu, Zhina Qu, Keguang Han

“…It highlighted the importance of the “One Health” approach and biosecurity measures and provided recommendations for the prevention of the spread of pathogens and resistance.…”
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Unveiling the Microbial Symphony of Amasi: A Targeted Metagenomic 16S rRNA, ITS, and Metabolites Insights Using Bovine and Caprine Milk by Betty Olusola Ajibade, Titilayo Adenike Ajayeoba, Saheed Sabiu, Konstantin V. Moiseenko, Sizwe Vincent Mbona, Errol D. Cason, Tatyana V. Fedorova, Oluwatosin Ademola Ijabadeniyi

“…., and <i>Penicillium</i> spp. were the probable pathogenic bacteria and fungi genera found, respectively. …”
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S100A13-driven interaction between pancreatic adenocarcinoma cells and cancer-associated fibroblasts promotes tumor progression through calcium signaling by Liuyuan Xia, Xin Guo, Dong Lu, Yixin Jiang, Xiaohui Liang, Yiwen Shen, Jiayi Lin, Lijun Zhang, Hongzhuan Chen, Jinmei Jin, Xin Luan, Weidong Zhang

“…Methods Bioinformatic analysis was employed to predict the pathogenic potential of CAFs and S100A13. Stable S100A13 knockdown CAFs were generated using a short hairpin RNA system. …”
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Cultivating crayfish (Procambarus clarkii) significantly enhances the quantity and diversity of soil microorganisms: evidence from the comparison of rice-wheat and rice-crayfish ro... by Hui Xu, Hui Xu, Dan Wang, Dan Wang, Dan Wang, Xuguang Li, Xuguang Li, Jiajia Li, Jiajia Li, Yu Xu, Yu Xu, Zhiqiang Xu, Zhiqiang Xu

“…In contrast, the bacterial functions in the rice-crayfish rotation model were more diverse, primarily including methylotrophy, human pathogens all and methanotrophy. The results of co-occurrence network analysis showed that crayfish farming enhanced the modularity of the soil microbial community, and revealed that the microbial network in rice-wheat soil had fewer nodes and more edges, which implying more internal connections. …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

“…It has been demonstrated that symbiont nontoxigenic Bf strains have a more effective “weapon” effect on pathogenic Bf, which is realized through the activity of effector-immune (E-I) protein pairs. …”
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Establishment and application of a one-step multiplex real-time PCR assay for detection of A, B, and C subtypes of avian metapneumovirus by Mingjun Su, Jiongze Cheng, Xiangwen Xu, Yijia Liu, Yulin Zhao, Yutao Wang, Xiaoxu Du, Jiale Ying, Junfang Yan, Huihua Zheng, Changyong Cheng, Jing Sun

“…This method demonstrates remarkable specificity, selectively amplifying aMPV-A, aMPV-B, and aMPV-C without cross-reactivity with other common avian pathogens. Furthermore, this method exhibits high sensitivity, with a detection threshold of 8.5 × 102 copies/μL for aMPV-A, aMPV-B, and aMPV-C. …”
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Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer by Olusola Olalekan Elekofehinti, Hannah Oluwaseun Popoola, Adedotun Olayemi Oluwatuyi, Opeyemi Iwaloye, Moses Orimoloye Akinjiyan, Oluwamodupe Cecilia, Frank Abimbola Ogundolie, Olalekan Isaac Olatunde, Oussama Abchir, Samir Chtita, Joao Batista Texeira Rocha

“…The clinical implication of apoptosis-signaling kinase 1 in the pathogenicity of colorectal cancer makes it an important drug target in the treatment of colorectal cancer. …”
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A study of the influence of the T2DL.2DS-2SS translocation and the 5S(5D) substitution from <i>Aegilops speltoides</i> on breeding-valuable traits of common wheat by R. O. Davoyan, I. V. Bebykina, E. R. Davoyan, A. N. Zinchenko, Y. S. Zubanova, D. M. Boldakov, V. I. Basov, E. D. Badaeva, I. G. Adonina, E. A. Salina

“…The assessment of the varieties’ resistance to rust diseases showed that Krasnodarskaya 99, Nika Kubani and the Aurora variety, which is a carrier of the T1BL.1RS translocation, are highly susceptible to diseases, while the presence of the T2DL.2DS-2SS translocation and the 5S(5D) substitution, both together and separately, provides resistance to fungal pathogens. The analysis of the lines using markers designed for known resistance genes of Ae. speltoides did not reveal the presence of the Lr28, Lr35 and Lr51 genes in the lines. …”
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Fecal microbiome change in patients with ulcerative colitis after fecal microbiota transplantation by A. Y. Tikunov, V. V. Morozov, A. N. Shvalov, A. V. Bardasheva, E. V. Shrayner, O. A. Maksimova, I. O. Voloshina, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…In some samples collected before FT, sequences of pathogenic Firmicutes and Proteobacteria were detected, including Acinetobacter spp., Enterococcusspp., Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus, Stenotrophomonas maltophylia, Streptococcusspp. …”
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Autosomal Recessive Bestrophinopathy: Clinical and Genetic Characteristics of Twenty-Four Cases by Hassan Khojasteh, Mohsen Azarmina, Nazanin Ebrahimiadib, Narsis Daftarian, Hamid Riazi-Esfahani, Houra Naraghi, Hamideh Sabbaghi, Alireza Khodabande, Hooshang Faghihi, Afrooz Moghaddasi, Fatemeh Bazvand, Masoud Reza Manaviat, Hamid Ahmadieh, Narges Hassanpoor, Fatemeh Suri

“…Our study also expands the pathogenic mutation spectrum of the BEST1 gene associated with ARB.…”
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Dietary supplementation with Epimedium contributes to the improvement of hormone levels, gut microbiota, and serum metabolite composition in the Chinese forest musk deer (Moschus b... by Shan Xie, Shan Xie, Qinlin Yang, Zaixiang Ying, Zaixiang Ying, Mingcheng Cai, Wenqiao Fan, Hanyu Gao, Hanyu Gao, Xiaolan Feng, Yongjiang Wu

“…The results indicated that the inclusion of Epimedium in the diet increased dry matter intake (DMI) and improved the ratio of feed to gain (F/G), with an increase in fecal testosterone levels (p &lt; 0.05). 16S rDNA sequencing analysis revealed that Epimedium enhanced the richness and diversity of the gut microbiota in the Chinese forest musk deer, increasing the relative abundance of beneficial bacteria such as Firmicutes, while reducing the relative abundance of the potentially pathogenic Proteobacteria (p &lt; 0.05). A widely targeted metabolomics analysis identified 25 differential metabolites between the two groups. …”
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Genetic divergence of hot pepper lines (Capsicum spp.) in hybrid combinations by Šević Biljana, Cvikić Dejan, Slađana Savić, Tupajić Ivan, Ugirnović Milan, Bajagić Marija, Luković Kristina, Stojiljković Jelena

“…Hybrids offer numerous advantages over varieties, including higher yields, fruit uniformity, resistance to plant pathogens, and the manifestation of heterosis. These are the primary reasons for initiating research on hybrid combinations of hot peppers. …”
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