Stage-specific function of sphingolipid synthases in African trypanosomes by Norton Heise, Carolina M. Koeller, Mohamed Sharif, James D. Bangs

“…These findings raise interesting questions about the roles of individual phosphosphingolipids in in vivo infection of the mammalian and tsetse hosts.IMPORTANCEAfrican trypanosomes are eukaryotic pathogens that cause human and veterinary African trypanosomaisis. …”
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Genotypic and Phenotypic Characterizations of Methicillin-Resistant Staphylococcus aureus (MRSA) on Frequently Touched Sites from Public Hospitals in South Africa by Siyethaba Mkhize, Daniel G. Amoako, Christiana O. Shobo, Oliver T. Zishiri, Linda A. Bester

“…The hospital environment acts as a reservoir in the transmission of pathogens, such as MRSA, which may cause hospital-acquired infections. …”
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Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs by Shuaiqi Liu, Shiheng Li, Shuqi Cheng, Manyu Liu, Jing Li, Senyang Li, Xiaoying Li, Longxian Zhang, Fuchun Jian

“…Abstract Background Coccidia are among the primary pathogens causing diarrhea and even fatalities in lambs. …”
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Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis by Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

“…Thus, our sRNA-based approach has broad potential as a conditional knockdown method for studying the function of C. trachomatis genes, including essential genes and genes in an operon.IMPORTANCEWe describe a new method to reduce protein levels of a selected gene in the pathogenic bacterium Chlamydia trachomatis. This approach utilizes an engineered small RNA (sRNA) to inhibit translation of the mRNA for a target gene and produced inducible and reversible protein knockdown. …”
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Isolasi dan Karakterisasi Bakteri Endofit dari Tanaman Binahong dan Katepeng China by Desriani ., Ukhradia Maharaniq Safira P, Maria Bintang, Akhmad Rivai, Puspita Lisdiyanti

“…Methods: The objective of this study was to isolate and to characterize endophytic bacteria from both plants through antibacterial activity test against to three kinds of human pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus cereus). …”
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Role of outer membrane vesicles of hypervirulent Klebsiella pneumoniae isolated from bovine uterine discharge in pro-inflammatory dysregulation by A. F. Daham, A. H. Jaber, A. Neamah, H. Al-Karagoly

“…This ability of hvKP OMVs to evade the immune system and modulate host responses contributes significantly to the bacterium’s pathogenicity.…”

Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown by Frank T. Aboagye, Lawrence Annison, Henry Kwadwo Hackman, Maame E. Acquah, Yvonne Ashong, Isaac Owusu-Frimpong, Bill C. Egyam, Sharon Annison, George Osei-Adjei, Samuel Antwi-Baffour

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A Multidisciplinary-Based and Bundle Intervention for Controlling Carbapenem-Resistant Organisms in Neurosurgery by Zhu W, Liang Y, Xu J, Weng C

“…The surveillance analysis and event analysis were used to identify the key links and targeted pathogens of the intervention. PDCA cycle management tool was used to strengthen the bundle management of multidisciplinary collaboration. …”
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Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients by Mohamed Abdel-Raoof Fouda, Mohamed Abdel-Wahhab, Ahmed Esmail Abdelkader, Mohsen El-Sayd Ibrahim, Taher Abozeid Elsheikh, Hisham Mohammad Aldeweik, Nora Elfeky

“…A change in gut microbiota composition was noted, characterized by a rise in potentially pathogenic bacteria such as Enterococci and Enterobacteriaceae (including Escherichia coli and Klebsiella) and a reduction in beneficial bacteria such as Bacteroidetes and Firmicutes. …”
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Isolation and Identification of Staphylococcus aureus from Milk and Milk Products, Associated Factors for Contamination, and Their Antibiogram in Holeta, Central Ethiopia by Endrias Zewdu Gebremedhin, Addisu Bedashu Ararso, Bizunesh Mideksa Borana, Kebede Abdisa Kelbesa, Nega Desalegn Tadese, Lencho Megersa Marami, Edilu Jorga Sarba

“…Staphylococcus aureus is a pathogenic bacterium-contaminating milk and milk products causing food poisoning primarily due to its enterotoxins. …”
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The enriched gut commensal Faeciroseburia intestinalis contributes to the anti-metabolic disorders effects of the Ganoderma meroterpene derivative by Shanshan Qiao, Kai Wang, Chang Liu, Nan Zhou, Li Bao, Jun Wang, Shuangjiang Liu, Hongwei Liu

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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…Abstract Introduction Blood-brain barrier (BBB) integrity is fundamental to brain homeostasis, enabling control of substance exchange and safeguarding neurons against harmful toxins, pathogens, and immune cells that lead to dysregulation and inflammation involved in ageing and neurodegenerative diseases (NDD). …”
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Morphological and Molecular Characterization of Trichoderma Isolates from Vegetable Crop Rhizospheres in Nepal [version 2; peer review: 1 approved, 2 approved with reservations] by Arvind Kumar Keshari, Suraj Baidya, Aashaq Hussain Bhat, Ram B. Khadka, Puja Jaiswal

“…Background Trichoderma spp. hold significant potential as biocontrol agents in agriculture due to their antagonistic properties against plant pathogens. The study aimed to characterize and identify Trichoderma isolates from rhizospheric regions of vegetable crops. …”
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Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review by Michele Lanza, Giuditta Benincasa, Dario Costa, Claudio Napoli

“…Hypermethylation of H3K4 and hypomethylation of H3K27 at the TGFBIp locus are putative pathogenic mechanisms involved in corneal dystrophies. …”
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How, why, where and when people feed birds?—Spatio‐temporal changes in bird‐feeding in Finland by Purabi Deshpande, Anna Haukka, Katja Rönkä, Tuomas Aivelo, Andrea Santangeli, Rose Thorogood, Aleksi Lehikoinen

“…While bird‐feeding can increase connections between people and nature, there are increasing calls from researchers and the general public to limit this activity due to emerging knowledge of potential negative ecological impacts (e.g. biased competition and spread of pathogens). However, what motivates changes in bird‐feeding habits remains largely unknown, despite the ‘provisioners’ perspective’ being critical for designing and implementing policy that benefits both animals and people. …”
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<i>Toxoplasma gondii</i> and Rabies—The Parasite, the Virus, or Both? by Ragan Wilson, Shannon Caseltine, Edith Will, Jeremiah Saliki, Ruth C. Scimeca

“…Due to the overlapping clinical signs of these two pathogens, the objective of this study was to evaluate the prevalence of <i>T. gondii</i> DNA in cerebellum tissue collected for rabies testing; cerebellum tissue from diverse animals is often submitted for this purpose. …”
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Proteomic profiling of Labeo rohita intestine infected with Edwardsiella tarda: Unveiling the mucosal defense mechanisms, cell adhesion, and cytoskeletal pathways by Nevil Pinto, Mehar Un Nissa, Gowhar Iqbal, Yashwanth BS, Darshan P, Sanjeeva S, Mukunda Goswami

“…Introduction: The pathogenicity mechanism of the intestine induced by the enteric bacteria Edwardsiella tarda is essential for global aquaculture. …”
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TERT de novo mutation-associated dyskeratosis congenita and porto-sinusoidal vascular disease: a case report by Ge Yu, Guijie Xin, Xu Liu, Wanyu Li, Chen Shao, Runping Gao

“…A TERT c.2286 + 1G/A mutation in a splicing consensus site was identified in a patient with pulmonary fibrosis. Recently, a pathogenic de novo TERT c.280A > T variant was associated with diffuse lung disease in an infant. …”
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Regional insights on the prevalence and antimicrobial susceptibility pattern of carbapenem and colistin-resistant gram-negative bacteria: an observational cross-sectional study fro... by Nazia Khursheed, Fareeha Adnan, Moiz Ahmed Khan, Ramlla Hatif

“…Our study aimed to understand the prevalence of colistin resistance in carbapenem-resistant gram-negative bacteria, associated pathogens and their antimicrobial susceptibility pattern at our institute, to help limit further development of resistance. …”
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Comparative Outcomes of Meropenem–Vaborbactam vs. Ceftazidime–Avibactam Among Adults Hospitalized with an Infectious Syndrome in the US, 2019–2021 by Marya D. Zilberberg, Brian H. Nathanson, Mark A. Redell, Kate Sulham, Andrew F. Shorr

“…<b>Background/Objectives</b>: Meropenem–vaborbactam (MEV) and ceftazidime–avibactam (CZA) are active against “urgent threat” pathogens like carbapenem-resistant Enterobacterales (CRE). …”
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