He-Plasma Jet Generation and Its Application for E. coli Sterilization by Tiejian Liu, Yuxuan Zeng, Xin Xue, Yinyi Sui, Yingying Liang, Fushan Wang, Fada Feng

“…Atmospheric pressure plasma jet (APPJ) is a promising technique for the sterilization of pathogenic microorganisms in an ambient environment. …”
Get full text

Nosocomial Isolates and Their Drug Resistant Pattern in ICU Patients at National Institute of Neurological and Allied Sciences, Nepal by Pashupati Bhandari, Ganesh Thapa, Bharat Mani Pokhrel, Dwij Raj Bhatta, Upendra Devkota

“…This study was carried out from June 2011 to May 2012 at National Institute of Neurological and Allied Sciences Kathmandu, Nepal, with a view to determining drug resistant pathogens along with detection of extended spectrum β-lactamase (ESBL), AmpC β-lactamase (ABL), and metallo-β-lactamase (MBL) producing bacteria causing infection to ICU patients. …”
Get full text

Rust HUBB: DNA barcode-based identification of Pucciniales by Patricia Kaishian, Christopher R. K. Layug, Mark Anderson, Diane R. Berg, M. Catherine Aime

“…Abstract Rust fungi (Pucciniales, Basidiomycota) are a species-rich (ca. 8000 species), globally distributed order of obligate plant pathogens. Rust species are host-specific, and as a group they cause disease on many of our most economically and/or ecologically significant plants. …”
Get full text

Can Gut Microbiota Analysis Reveal <i>Clostridioides difficile</i> Infection? Evidence from an Italian Cohort at Disease Onset by Roberto Rosato, Gianluca Quaranta, Giulia Santarelli, Giovanni Fancello, Delia Mercedes Bianco, Francesca Romana Monzo, Stefano Bibbò, Giovanni Cammarota, Maurizio Sanguinetti, Luca Masucci, Flavio De Maio

“…A diverse and well-functioning gut microbiota normally serves as a protective shield against the invasion of harmful bacteria or the proliferation of opportunistic pathogens. <i>Clostridioides difficile</i> infection (CDI) is predominantly associated with the overuse of antibiotics, resulting in a significant alteration in the gut’s microbial balance. …”
Get full text

OK-432 Acts as Adjuvant to Modulate T Helper 2 Inflammatory Responses in a Murine Model of Asthma by Cheng-Jang Wu, Pin-Hsun Tseng, Cheng-Chi Chan, Sara Quon, Li-Chen Chen, Ming-Ling Kuo

“…The results obtained in this study lead us to propose a potential novel adjuvant for clinical use such as prophylactic vaccination for pathogens and immunotherapy in atopic diseases.…”
Get full text

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson’s Disease Penetrance by Alessandra Zanon, Peter P. Pramstaller, Andrew A. Hicks, Irene Pichler

“…Many mutations are clearly pathogenic in some patients while carriers of other mutations either do not develop the disease or show a delayed onset, a phenomenon known as reduced penetrance. …”
Get full text

A novel isothermal whole genome sequencing approach for Monkeypox Virus by Matthias Licheri, Manon Flore Licheri, Lukas Probst, Cora Sägesser, Pascal Bittel, Franziska Suter-Riniker, Ronald Dijkman

“…Whole genome sequencing (WGS) has been successfully used to keep track of viral evolution during outbreaks or for surveillance of multiple pathogens of public health significance. Current WGS protocols for MPXV are either based on metagenomic sequencing or tiled-PCR amplification. …”
Get full text

Phased Ions‐Release Bilayer‐Guided Bone Regeneration Membrane with Nanostructure‐Mediated Antibacterial Adhesion by Liguo Zhang, Zhao Li, Yajing Fu, Haoyang Tian, Ting Wang, Hongrui Liu, Jianhua Li, Hong Liu, Shaohua Ge, Baojin Ma

“…Furthermore, the nanoengineered HAp layer deters pathogenic colonization due to the low adhesion force, which can effectively prevent the formation of bacterial biofilms and infection after implantation. …”
Get full text

Parathyroid carcinoma and pheochromocytoma in a patient with neurofibromatosis type 1: a rare association by Jardelina Brena Rocha Leite, Nicole Ramalho De Freitas, Rafaella Nelice de Holanda Cardoso, Erik Trovão Diniz, Gabriel Rodrigues de Assis Ferreira, Fernão Henrique Costa e Alvim, Camila Ribeiro Coutinho Madruga, Ana Carolina Thé Garrido, Luciano Albuquerque, Patricia Sampaio Gadelha, Ruy Lyra, Lucio Vilar

“…Genetic analysis corroborated NF1 with a pathogenic variant in the NF1 gene. The patient’s clinical manifestations, coupled with the presence of café-au-lait spots and axillary freckles, supported the diagnosis of NF1. …”
Get full text

Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene by Haibin Chen, Haibin Chen, Yudi Zhang, Xueyao Yang, Xueyao Yang, Yongzhen Li

“…The missense mutation was determined to be both pathogenic and novel.ConclusionEarly genetic testing should be prioritized, and regular monitoring of kidney development and hearing status is essential. …”
Get full text

UV-C Radiation as a Factor Reducing Microbiological Contamination of Fish Meal by Krzysztof Skowron, Justyna Bauza-Kaszewska, Zbigniew Dobrzański, Zbigniew Paluszak, Karolina Jadwiga Skowron

“…Fish meals, added to feeds as a source of protein, may contain pathogenic bacteria. Therefore, effective methods for their sanitizing, such as UV-C radiation, are needed to minimize the epidemiological risk. …”
Get full text

<i>Bacillus velezensis</i> TCS001 Enhances the Resistance of Hickory to <i>Phytophthora cinnamomi</i> and Reshapes the Rhizosphere Microbial Community by Chenshun Xie, Yuntian Wu, Zhonghao Wu, Hao Cao, Xiaohui Huang, Feng Cui, Shuai Meng, Jie Chen

“…These findings underscore the influence of TCS001 on the hickory rhizosphere microbiome in the presence of pathogens, providing valuable data for future research and the development of effective biocontrol strategies for hickory root rot.…”
Get full text

Discovery of antimicrobial activity in chemical extracts derived from unexplored algal-bacterial culture systems and isolates by Carolyn L. Fisher, Hailey C. Loehde-Woolard, Pamela D. Lane, Catherine M. Mageeney, Todd W. Lane

“…Identifying novel antimicrobials through innovative methods that are active against human pathogens will create a new, necessary pipeline for chemical discovery and therapeutic development. …”
Get full text

Enhancing antimicrobial resistance strategies: Leveraging artificial intelligence for improved outcomes by Aeshah M. Mohammed, Mohammed Mohammed, Jawad K. Oleiwi, Azlin F. Osman, Tijjani Adam, Bashir O. Betar, Subash C.B. Gopinath, Falah H. Ihmedee

“…This review explores the burgeoning role of artificial intelligence (AI) in revolutionizing AMR strategies, offering a beacon of hope for turning the tide against resistant pathogens. By synthesizing current research and applications, the potential of AI-driven technologies—ranging from machine learning models that predict resistance patterns to algorithms enhancing antibiotic discovery—is illuminated to augment our arsenal against AMR. …”
Get full text

PPARγ Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung by Virender K. Rehan, John S. Torday

“…By exploiting such deep cell-molecular functional homologies as targets for leveraging lung homeostasis, we have discovered that we can effectively prevent and/or reverse the deleterious effects of these pathogenic agents, demonstrating the utility of evolutionary biology for the prevention and treatment of chronic lung disease. …”
Get full text

Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility by Iliana Alejandra Cortés-Ortíz, Gustavo Acosta-Altamirano, Rafael Nambo-Venegas, Jesús Alejandro Pineda-Migranas, Oscar Giovanni Ríos-Hernández, Eduardo García-Moncada, Alejandra Yareth Bonilla-Cortés, Mónica Sierra-Martínez, Juan Carlos Bravata-Alcántara

“…Objective: The aim of this study was to characterize the vaginal microbiota of 136 Mexican women diagnosed with infertility—primary (n = 58) and secondary (n = 78)—by evaluating the presence of pathogenic bacterial species and their associations with infertility conditions. …”
Get full text

Distribution and Genetic Diversity of Salmonella enterica in the Upper Suwannee River by Masoumeh Rajabi, Melissa Jones, Michael Hubbard, Gary Rodrick, Anita C. Wright

“…However, some Suwannee River isolates (12%) were clustered with these primarily clinically-associated genogroups, supporting the hypothesis that river water can serve as a disease reservoir and that pathogenic strains may persist or possibly originate from environmental sources.…”
Get full text

Ketamine-associated upper urinary tract dysfunction: What we know from current literature by Zhihuan Zheng, Zhongyi Li, Jiazhe Yuan, Feng Han, Li Huang, Zhao Wang

“…Oxidative stress, autophagy, and microvascular injury are also potential pathogenic mechanisms. The detection of these symptoms largely depends on laboratory and imaging examinations. …”
Get full text

Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge in mice by David W. Hawman, Thomas Tipih, Eddie Hodge, E. Taylor Stone, Nikole Warner, Natalie McCarthy, Brian Granger, Kimberly Meade-White, Shanna Leventhal, Kiara Hatzakis, Stephanie Park, Karen Gaffney, Kyle Rosenke, Jesse H. Erasmus, Heinz Feldmann

“…Abstract The ongoing circulation of influenza A H5N1 in the United States has raised concerns of a pandemic caused by highly pathogenic avian influenza. Although the United States has stockpiled and is prepared to produce millions of vaccine doses to address an H5N1 pandemic, currently circulating H5N1 viruses contain multiple mutations within the immunodominant head domain of hemagglutinin (HA) compared to the antigens used in stockpiled vaccines. …”
Get full text

Neurophysiology of Drosophila Models of Parkinson’s Disease by Ryan J. H. West, Rebecca Furmston, Charles A. C. Williams, Christopher J. H. Elliott

“…Secondly, models show noncell autonomous signalling within the nervous system, offering the opportunity to develop our understanding of the way pathogenic signalling propagates, resembling Braak’s scheme of spreading pathology in PD. …”
Get full text