A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers by Ersen Kameri, Ersen Kameri, Ersen Kameri, Vera Helena Jepsen, Pawel Stachura, Pawel Stachura, Nadine Rüchel, Rigveda Bhave, Leticia Benitez, Fatima Crispi, Eduard Gratacos, Nico Dragano, Stefan Janssen, Arndt Borkhardt, Arndt Borkhardt, Aleksandra Pandyra, Aleksandra Pandyra, Aleksandra Pandyra, Gesine Kögler, Gesine Kögler, Ute Fischer, Ute Fischer, Ute Fischer

“…Commensal gut microbiota provide a first line of defense against different pathogens and gut microbiome immaturity has been implicated in ALL pathogenesis. …”
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Green guardians: The biocontrol potential of Pseudomonas-derived metabolites for sustainable agriculture by Ruihuan Yang, Xiangning Du, Moein Khojasteh, Syed Mashab Ali Shah, Yongzheng Peng, Zhangfei Zhu, Zhengyin Xu, Gongyou Chen

“…It discusses the chemical diversity of these metabolites, their broad-spectrum bioactivities against pathogenic bacteria and fungi, oomycetes, nematodes, and their modes of action. …”
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Novel Implications in Molecular Diagnosis of Lynch Syndrome by Raffaella Liccardo, Marina De Rosa, Paola Izzo, Francesca Duraturo

“…Very often, the molecular analysis reveals the presence of variants of unknown significance (VUSs) whose interpretation is not easy and requires the combination of different analytical strategies to get a proper assessment of their pathogenicity. In some cases, these VUSs may make a more substantial overall contribution to cancer risk than the well-assessed severe Mendelian variants. …”
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Dialectics and Implications of Natural Neurotropic Autoantibodies in Neurological Disease and Rehabilitation by A. B. Poletaev, A. A. Abrosimova, M. A. Sokolov, A. B. Gekht, V. V. Alferova, E. I. Gusev, T. Ya. Nikolaeva, C. Selmi

“…Our observations suggest that changes in the production of natural neurotropic Abs may engender a positive homeostatic, beside a possible pathogenic effect, in specific neurological disorders.…”
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Preliminary study on antimicrobial activities of skin mucus from by-catch of Elasmobranch species by Aydoğdu Elif Özlem Arslan, Kesiktaş Mert, Sanli Nazmiye Ozlem, Güngör Nihal Doğruöz, Sancar Serap, Yildiz Taner, Yemişken Emre

“…The assays indicated that both the isolates and the skin mucus have potential antimicrobial activity against opportunistic pathogens.…”
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Zoonotic Ectoparasite Burden in House Rats (Rattus spp.) in Selected Urban and Rural Areas of NCR and CALABARZON by Helenar Chan, Mary Jane Flores, Eligio Santiago Maghirang, Bridget Arellano, Jan Michael Chan

“…Aside from endoparasites, ectoparasites such as lice, mites, ticks, and fleas, can also serve as vectors of various pathogens inducing diseases and contaminating the environment. …”
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Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant by Zhiqin Du, Xiao Ma, Xiao Ma, Xiao Ma, Jianhua Li, Fang Yang, Yangfan Guo, Yangfan Guo

“…The co-occurrence of a bicuspid aortic valve (BAV) with TSC is exceedingly rare.Case summaryWe report the case of a 26-year-old woman with genetically confirmed TSC, harboring a novel pathogenic variant in the TSC2 gene. Cardiovascular characteristics included a history of heart valve disease, a bicuspid aortic valve, and severe aortic regurgitation. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone. …”
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Micromechanical behavior of the apple fruit cuticle investigated by Brillouin light scattering microscopy by Timm Landes, Bishnu P. Khanal, Hans Lukas Bethge, Tina Lehrich, Maximilian Seydi Kilic, Franz Renz, Miroslav Zabic, Moritz Knoche, Dag Heinemann

“…It regulates water loss and defends against environmental stressors and pathogens. Despite its significance, understanding of the micro-mechanical properties of the cuticle (cuticular membrane; CM) remains limited. …”
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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

“…Recessive dystrophic epidermolysis bullosa (RDEB) is a severe blistering disease caused by COL7A1 pathogenic variants. Although underscored by animal studies, the endotypes of human RDEB are poorly understood. …”
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Multiorgan Failure and Refractory Lactic Acidosis due to Pasteurella multocida Septicemia in a Patient with No Animal Exposure by Damaris Pena, Yaneidy Santana, Jose Perez Lara, Efrain Gonzalez, Misbahuddin Khaja

“…Pasteurella multocida is a gram-negative coccobacillus pathogenic to animals. It can cause infection in humans by a bite, scratch, or lick from a cat or dog. …”
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Monkeypox: a re-emergent virus with global health implications – a comprehensive review by Nourhan G. Naga, Enas A. Nawar, A’laa A. Mobarak, Aya G. Faramawy, Hend M. H. Al-Kordy

“…The epidemic is divided into two clades: Clade I and Clade II, which have distinct pathogenic characteristics. Diagnostic approaches have developed with advances in molecular techniques, yet problems persist in resource-constrained situations. …”
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COVID-19 vaccination: challenges in the pediatric population by Alice Nicoleta Azoicai, Ingrith Miron, Ancuta Lupu, Monica Mihaela Alexoae, Iuliana Magdalena Starcea, Mirabela Alecsa, Vasile Valeriu Lupu, Ciprian Danielescu, Alin Horatiu Nedelcu, Delia Lidia Salaru, Felicia Dragan, Ileana Ioniuc

“…Vaccination is considered to be one of the most effective means of protecting individuals and populations from the risks associated with exposure to various pathogens. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected people of all ages worldwide. …”
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Development of a differentiating of infected from vaccinated animal (DIVA) ELISA to detect antibodies against Senecavirus A in pigs using two expression systems of non-structural p... by Parin Watcharavongtip, Patumporn Jermsutjarit, Angkana Tantituvanont, Dachrit Nilubol

“…Both ELISAs strongly correlated with the reference method and showed no cross-reactivity with other pig pathogens. The E. coli system also provided a higher yield of expressed protein than the baculovirus system. …”
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Large Right Atrial Thrombus Associated with Central Venous Catheter Requiring Open Heart Surgery by Nasir Hussain, Paul Eric Shattuck, Mourad Hussein Senussi, Erwin Velasquez Kho, Mubeenkhan Mohammedabdul, Devang K. Sanghavi, Usman Mustafa, Arvind Balavenkataraman, Dragic M. Obradovic

“…Incidences of CVC-related right atrial thrombosis (CRAT) are variable, but, when right atrial thrombus is present, it carries a mortality risk of 18% in hemodialysis patients and greater than 40% risk in nonhemodialysis patients. Different pathogenic mechanisms have been postulated for the development of CRAT, which includes mechanical irritation of the myocardial wall, propagation of intraluminal clot, hypercoagulability, and hemodynamics of right atria. …”
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The Effects of Microplastic Pollution on Marine Organisms and its Impact on Human Health: A Review by Aran Akbari, Jalil Jaafari

“…MPs in marine environments provide a highly selective and flexible support platform for a variety of microbial communities, especially resistant pathogens. The accumulation of MPs in marine organisms consumed as human food has dangerous consequences for human health, leading to physical and chemical toxic effects. …”
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Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution by Stéphane Rodriguez, Stéphane Rodriguez, Laura Couloume, Juliette Ferrant, Juliette Ferrant, Nicolas Vince, Marion Mandon, Marion Mandon, Rachel Jean, Rachel Jean, Celine Monvoisin, Simon Leonard, Simon Le Gallou, Simon Le Gallou, Nayane S. B. Silva, Nayane S. B. Silva, Sonia Bourguiba-Hachemi, David Laplaud, David Laplaud, Alexandra Garcia, Romain Casey, Romain Casey, Romain Casey, Romain Casey, Helene Zephir, Anne Kerbrat, Gilles Edan, Emmanuelle Lepage, Eric Thouvenot, Eric Thouvenot, Aurelie Ruet, Aurelie Ruet, Guillaume Mathey, Guillaume Mathey, Pierre-Antoine Gourraud, Pierre-Antoine Gourraud, Karin Tarte, Karin Tarte, Celine Delaloy, Patricia Amé, Patricia Amé, Mikael Roussel, Mikael Roussel, Laure Michel, Laure Michel, Laure Michel

“…Furthermore, pathways analysis predicted that these cells had antigen presentation capabilities coupled with pro-inflammatory phenotype.DiscussionAltogether, these results point toward the amplification of a specific and pathogenic myeloid cell subset in MS patients with genetic susceptibilities.…”
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Mixed Ligand Complexes of N-Methyl-N-phenyl Dithiocarbamate: Synthesis, Characterisation, Antifungal Activity, and Solvent Extraction Studies of the Ligand by Anthony C. Ekennia, Damian C. Onwudiwe, Cyril Ume, Eno E. Ebenso

“…The compounds were screened for three human pathogenic fungi: Aspergillus flavus, Aspergillus niger, and Candida albicans. …”
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Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins by Sajad Chamani, Vanessa Bianconi, Aida Tasbandi, Matteo Pirro, George E. Barreto, Tannaz Jamialahmadi, Amirhossein Sahebkar

“…In recent years, compelling evidence has shown that impairment of resolution of inflammation is a crucial pathogenic hallmark in different neurodegenerative disorders, including Alzheimer’s disease and Parkinson’s disease. …”
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Chronic Lymphocytic Leukemia and Myelofibrosis by Fares Darawshy, Arieh Ben-Yehuda, Karine Atlan, Deborah Rund

“…This case reported here constitutes an unusual situation of CLL characterized by the development of PMF. Etiologic and pathogenic associations—the role of t (1; 6) and JAK-2 V617F mutation—are discussed.…”
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Transcriptional regulation of suberin and its response to the environment by ZHOU Yue, AN Yongping, MA Rong, WANG Pei

“…Acting as a barrier between the plants and their environment, suberin controls the transport of water and solutes, protecting plants from environmental stresses and pathogenic invasion. This article reviews the key enzymes and transcription factors involved in suberin biosynthesis, and discusses the impact of environmental factors on suberin synthesis and deposition. …”
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