cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

“…The cGAS/STING signaling pathway, a pivotal mechanism in innate immunity, detects cytosolic DNA from pathogens or cellular damage, triggering immune responses via type I interferons and inflammatory cytokines. …”
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mGBP2 engages Galectin-9 for immunity against Toxoplasma gondii. by Elisabeth Kravets, Gereon Poschmann, Sebastian Hänsch, Veronica Raba, Stefanie Weidtkamp-Peters, Daniel Degrandi, Kai Stühler, Klaus Pfeffer

“…Murine GBPs (mGBPs) recognize T. gondii PVs and assemble into supramolecular mGBP homo- and heterocomplexes that are required for the disruption of the membrane of PVs eventually resulting in the cell-autonomous immune control of vacuole-resident pathogens. We have previously shown that mGBP2 plays an important role in T. gondii immune control. …”
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Prevalence of Brucellosis among Women Presenting with Abortion/Stillbirth in Huye, Rwanda by Nadine Rujeni, Léonidas Mbanzamihigo

“…More mechanistic studies will also demonstrate the pathogenicity of Brucella in human placentas.…”
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A review on the microbiology of Ethiopian traditional fermented beverage products by Guesh Mulaw, Trhas Gebregziabher, Teklemichael Tesfay

“…It also helps to reduce the amount of toxins and pathogens in food. Similarly, fermented foods contain probiotics, which are beneficial bacteria that help the body to digest food and absorb nutrients. …”
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Theoretical Construction and Clinical Application of "Flaccidity Caused by Deficiency and Congestion" of Osteoporosis by YAO Xinmiao

“…Based on the basic theories such as "kidney governing bone" and "kidney deficiency", professor YAO Xinmiao of The Third Affiliated Hospital of Zhejiang Chinese Medical University creatively put forward the pathogenic theory of "flaccidity caused by deficiency and congestion" of OP, which holds that the pathogenesis of OP is the combination of deficiency and blood stasis, mixed with impotence. …”
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The growing challenge of autism spectrum disorder: a comprehensive review of etiology, diagnosis, and therapy in children by Chunyuan Wang, Hong Wang

“…Finally, this paper summarizes the current status of autism research, looks forward to future research directions, and calls for more research to explore the pathogenic mechanisms, diagnostic basis, and therapeutic methods of autism.…”
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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

“…Iron plays a key role in many of the key pathogenic steps concurring in the development and progression of MFLS, notably including genetics, intestinal dysbiosis, adipositis, insulin resistance, metaflammation, oxidative stress and ferroptosis, endoplasmic reticulum stress, and hepatic fibrosis. …”
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Preparation of Copper Nanoparticles/Diatomite Nanocomposite for Improvement in Water Quality of Fishponds by Truong Thi Hanh, Nguyen Thuy Lan Chi, Nguyen Ngoc Duy

“…Antibacterial activity of CuNPs/DA nanocomposite against pathogenous bacteria for catfish such as Aeromonas hydrophila and Edwardsiella ictaluri was estimated.…”
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Necrotizing Epididymo-Orchitis: A Rare Manifestation of COVID-19 by Ali Tavoosian, Sana Ahmadi, Seyed Mohammad Kazem Aghamir

“…It is caused by sexually transmitted microorganisms and nonsexual transmitted pathogens. Viruses such as mumps and cytomegalovirus can also cause epididymo-orchitis. …”
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Portrait global de l’exposition aux contraintes psychosociales au travail des paramédics québécois by Sandrine Hegg-Deloye, Patrice Brassard, Jérôme Prairie, Dominique Larouche, Nathalie Jauvin, Angelo Tremblay, Philippe Corbeil

“…Psychosocial constraints at work are a major concern, since they can have a pathogenic effect on the mental and physical health of workers. …”
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Light and electron microscopic studies on the cellular and humoral defensive systems of the mammary glands of normal and mastitic cows by İlhami Çelik, Reşat N. Aştı

“…<p> Since the infectious agents generally reach at the parenchymal tissues through the streak canal, Furstenberg's rosette area which is highly populated with the defensive cells may play an important role in preventing the mammary tissues from invading mammary pathogens.…”
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Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus by Termpanit Chalermpalanupap, David Weinshenker, Jacki M. Rorabaugh

“…In this review, we combine the literature on how pathogenic tau affects forebrain neurons with the known properties and degeneration patterns of LC neurons to synthesize hypotheses on hyperphosphorylated tau-induced dysfunction of LC neurons and the prion-like spread of pretangle tau from the LC to the forebrain. …”
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Electroacupuncture Stimulation Suppresses Postoperative Inflammatory Response and Hippocampal Neuronal Injury by Xiang-feng Wang, Qin Lin, Guan-hui Wang, Gen-ming Zhan, Wei Liu, Zhi-wei Lin

“…These findings indicated the POCD was the synergistic outcome of anaesthesia and surgical stimulation but with different pathogenic mechanism. The surgery with mental tri-needles (surgery+MTN) group outperformed the surgery group in terms of cognitive function performance. …”
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Microevolution during Chronic Infection May Lead T. asahii to Coexist with the Host by Gen Ba, Xuelian Lv, Xin Yang, Wenling Wang, Junhong Ao, Rongya Yang

“…Compared with the primary T. asahii strain, the microevolved strain induced much lower expression of TNF-α by mice bone marrow-derived DC and had a much superior survival rate, a total of 2212 significantly differentially expressed genes were identified in the microevolved strain, and functional analysis showed significance in the downregulated transcription and metabolic process, especially the valine, leucine, and isoleucine degradation pathways, which were associated with pathogenicity and virulence; hence, the results were highly consistent with the decreased immunogenicity and virulence of the microevolved strain. …”
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Cyst Nematode (Heterodera glycines) Problems in Soybean (Glycine max L.) Crops and Its Management by Gebissa Yigezu Wendimu

“…Hence, the reason behind the writing of this chapter is to explore the different published scientific papers related to soybean cyst nematode’s economic importance, distribution, symptoms, biology, life cycle, interaction with other pathogens, different management approaches, and its prospects. …”
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Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue by Sofia Dias, Sílvia Paredes, Laura Ribeiro

“…Obesity and dyslipidemia are main features of metabolic syndrome, and both can present with adipose tissue dysfunction, involved in the pathogenic mechanisms underlying this syndrome. We revised the effects, and underlying mechanisms, of the current approved drugs for dyslipidemia and obesity (fibrates, statins, niacin, resins, ezetimibe, and orlistat; sibutramine; and diethylpropion, phentermine/topiramate, bupropion and naltrexone, and liraglutide) on adipose tissue. …”
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Green-Synthesized Sm3+-Doped ZnO Nanoparticles for Multifunctional Applications by Lavanya R., Ramakrishnappa T., Girish K. M., Suresh Kumar K., Basavaraju N., Shilpa B. M.

“…The antibacterial activity was performed against two pathogenic strains, i.e., Escherichia coli and Streptococcus aureus. …”
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What Veterinarians Need to Know About the Newly-Emerging Field of Insects-as-Food-and-Feed by Kimberly L. Boykin, Mark A. Mitchell

“…Veterinarians interested in working with these species will need to become knowledgeable regarding the diseases afflicting the feeder insect industry and how best to diagnose and treat pathogens of concern. Using the edible cricket industry as an example, this review will highlight health and production issues while drawing similarities to other traditional livestock operations. …”
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A systematic review to identify research gaps in studies modeling MenB vaccinations against Neisseria infections. by Soeren Metelmann, Alexander Thompson, Anna Donten, Segun Oke, Suzy Sun, Ray Borrow, Feng Xu, Roberto Vivancos, Valerie Decraene, Lorenzo Pellis, Ian Hall

“…The genus Neisseria includes two major human pathogens: N. meningitidis causing bacterial meningitis/septicemia and N. gonorrhoeae causing gonorrhoea. …”
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Chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition) by Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention, Wei Zhao

“…This edition of the Guidelines covers 14 sections: epidemiology, pathogenic characteristics, laboratory tests, pathogenesis, clinical presentation and staging, diagnostic criteria, common opportunistic infections, antiretroviral therapy, immune reconstitution inflammatory syndrome, incomplete immune reconstitution, AIDS-related neoplasms, prevention of mother-to-child transmission and conception in serodiscordant couples, pre- and post-exposure prophylaxis, and whole-course management of HIV infection. …”
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