Suggested Topics within your search.
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- Microbiology 2
- Biology 1
- Clinical 1
- Human Microbial 1
- Infections 1
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4281
Analysis of Fenton iron sludge and application in wastewater treatment
Published 2024-12-01“…Fenton iron sludge contains a significant amount of iron, alongside hard-to-degrade organic pollutants, sediments, pathogens, and heavy metals. If not managed properly, these constituents can cause secondary pollution and waste resources. …”
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4282
Case report: a rare concurrence of dense deposit disease in an adolescent patient with IgA nephropathy
Published 2025-01-01“…The presence of both in a single patient may result in more intricate pathogenic pathways. Conclusions This specific case elucidates the pathological characteristics of both diseases while investigating the intricate connections and lesion correlations that may occur between them, offering novel insights into their pathogenesis.…”
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4283
SLE and Non-Hodgkin’s Lymphoma: A Case Series and Review of the Literature
Published 2017-01-01“…The cause and effect relationships of lymphoma in SLE have been subject to extensive scrutiny with several studies reporting on clinic-pathologic characteristics and risk factors predicting lymphoma development in SLE. However, the pathogenic role of immunosuppressives in SLE-related lymphoma still remains unclear, and indices to help guide diagnosis, prognostication, therapy, and posttreatment monitoring are yet to be established. …”
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4284
Nucleotide-Binding Oligomerization Domain-1 and -2 Play No Role in Controlling Brucella abortus Infection in Mice
Published 2012-01-01“…Further, several in vivo studies have demonstrated a role for Nod1 and Nod2 in host defense against bacterial pathogens. Here, we demonstrated that macrophages from NOD1-, NOD2-, and Rip2-deficient mice produced lower levels of TNF-α following infection with live Brucella abortus compared to wild-type mice. …”
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4285
Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways
Published 2025-03-01“…The exact underlying pathogenic mechanism(s) remain elusive. This is particularly the case for sporadic ALS (sALS), representing 90 % of cases, as modelling a sporadic disease is extremely difficult. …”
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4286
Biofabrication of brain-like living tissue: structure to intelligence
Published 2025-01-01“…Brain diseases are among the leading threats to human life, yet our understanding of their pathogenic mechanisms and drug development remains limited, largely due to the lack of accurate brain-like tissue models that replicate its complex structure and functions. …”
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4287
A multiplex method for rapidly identifying viral protease inhibitors
Published 2025-01-01“…Abstract With current treatments addressing only a fraction of pathogens and new viral threats constantly evolving, there is a critical need to expand our existing therapeutic arsenal. …”
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4288
Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections
Published 2012-01-01“…Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) are amongst the most common human infectious viral pathogens capable of causing serious clinical diseases at every stage of life, from fatal disseminated disease in newborns to cold sores genital ulcerations and blinding eye disease. …”
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4289
Recent advances in the science of human milk oligosaccharides
Published 2025-01-01“…Approximately 200 varieties of HMOs have been characterized.Although HMOs are not utilized as an energy source by infants, they have important protective functions, including pathogenic bacteria and viral infection inhibitors and immune modulators, among other functions, and HMOs stimulate brain-nerve development. …”
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4290
Leishmaniasis and Climate Change—Case Study: Argentina
Published 2012-01-01“…From the biological point of view interaction of different variables has different and even conflicting effects on the survival of vectors and the probability transmission of pathogens. The results on ecoepidemiology of leishmaniasis in Argentina related to climate variables at different scales of space and time are presented. …”
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4291
Research progress in prevention and nursing of shoulder-hand syndrome in stroke patients (中风患者肩手综合征的预防与护理进展)
Published 2024-07-01“…This article describes the clinical manifestations and pathogenic factors of shoulder-hand syndrome, and summarizes its preventive measures and clinical nursing measures in order to provide new ideas for clinical nursing. …”
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4292
PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma
Published 2025-01-01“…Abstract Besides the important pathogenic mechanisms of melanoma, including BRAF-driven and immunosuppressive microenvironment, genomic instability and abnormal DNA double-strand breaks (DSB) repair are significant driving forces for its occurrence and development. …”
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4293
A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion
Published 2025-03-01“…Hepatitis B virus (HBV) represents one of the major pathogenic factor that leads to chronic liver diseases and the development of hepatocellular carcinoma (HCC). …”
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4294
Organic disinfectant using coconut shell liquid smoke in the chicken slaughterhouse wastewater treatment plant
Published 2025-01-01“…Wastewater treatment in Chicken Slaughterhouse is absolutely necessary because it has a very positive impact on environmental preservation and helps remove pathogenic organisms in wastewater before being discharged into the environment. …”
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4295
Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics
Published 2025-02-01“…While they help capture and eliminate pathogens, NETs’ excessive or dysregulated formation can lead to tissue damage and disease progression. …”
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4296
Homeostatic antiviral protection of the neonatal gut epithelium by interferon lambda
Published 2025-02-01“…Summary: Cell-intrinsic antiviral gene expression by intestinal epithelial cells (IECs) limits infection by enteric viral pathogens. Here, we find that neonatal IECs express antiviral genes at homeostasis that depend on interferon lambda (IFN-λ) and are required for early control of mouse rotavirus (mRV) infection. …”
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4297
The Regulatory Effects of mTOR Complexes in the Differentiation and Function of CD4+ T Cell Subsets
Published 2020-01-01“…T cells are an important part of the adaptive immune system and play critical roles in the elimination of various pathogens. T cells could differentiate into distinct cellular subsets under different extracellular signals and then play different roles in maintaining host homeostasis and defense. …”
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4298
Epigenetic Control of Interferon-Gamma Expression in CD8 T Cells
Published 2015-01-01“…Interferon- (IFN-) γ is an essential cytokine for immunity against intracellular pathogens and cancer. IFN-γ expression by CD4 T lymphocytes is observed only after T helper (Th) 1 differentiation and there are several studies about the molecular mechanisms that control Ifng expression in these cells. …”
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4299
The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests
Published 2011-01-01“…Bovine tuberculosis (bTB) is diagnosed in naturally infected populations exposed to a wide variety of other pathogens. This study describes the cell-mediated immune responses of cattle exposed to Mycobacterium avium subspecies paratuberculosis (Map) and Mycobacterium avium subspecies avium with particular reference to routine antefmortem Mycobacterium bovis diagnostic tests. …”
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4300
Antibiotic, Pesticide, and Microbial Contaminants of Honey: Human Health Hazards
Published 2012-01-01“…Pesticide residues cause genetic mutations and cellular degradation and presence of antibiotics might increase resistant human or animal's pathogens. Many cases of infant botulisms have been attributed to contaminated honey. …”
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