Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children by Christophe Faure

“…Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation. …”
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Conventional Medicinal Uses, Phytoconstituents, and Biological Activities of Euphorbia officinarum L.: A Systematic Review by Imane Chamkhi, Mohamed Hnini, Jamal Aurag

“…It is also used against human pathogens (intestinal parasites). E. officinarum latex is the major part of the plant used for conventional medicine and synthesizing new bioactive compounds. …”
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Skin Immune Landscape: Inside and Outside the Organism by Florence Abdallah, Lily Mijouin, Chantal Pichon

“…The skin is an essential organ to the human body protecting it from external aggressions and pathogens. Over the years, the skin was proven to have a crucial immunological role, not only being a passive protective barrier but a network of effector cells and molecular mediators that constitute a highly sophisticated compound known as the “skin immune system” (SIS). …”
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The Potential of Secondary Metabolites in Medicinal Plants as Anti–Quorum Sensing in Biofilms: A Comprehensive Review by Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia

“…This review summarizes the study of quorum sensing systems acting on Gram-positive and Gram-negative bacteria, the role of quorum sensing on biofilm formation by pathogenic bacteria, and the potential use of medicinal plants as natural anti–quorum sensing agents reviewed in vitro and in silico. …”
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Pests and Fungal Organisms Identified on Olives (Olea europaea) in Florida by Jennifer L. Gillett-Kaufman, Sandra A. Allan, Jonael H. Bosques-Mendez, Lyle J. Buss

“…Fortunately, olives are a relatively pest-free species, but some occasional invaders can be a nuisance or cause lasting harm. A few plant pathogens that may infect olives also can lead to a decline in overall plant health, fruit yield, or the visual appearance of plants. …”
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Particulate Matter-Induced Acute Coronary Syndrome: MicroRNAs as Microregulators for Inflammatory Factors by Nur Izah Ab Razak, Nor Eliani Ezani, Norzian Ismail

“…Exposure to particulate matter (PM) from air pollution has been shown to impair both. Various plausible pathogenic mechanisms have been identified, including microRNAs (miRNAs), an epigenetic regulator for gene expression. …”
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Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment by L. Yu. Il’chenko, V. I. Reshetn’yak

“…Combined treatment of UDCA and budesonide is proposed.Conclusion. UDCA is pathogenicly proved treatment of PBC.…”
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Microbiological Study of Cast Posts before Cementation by Maricela Vallejo-Labrada, Juan Carlos Ojeda-Garces

“…The disinfection process worked out in a high percentage and demonstrated that the sterilization by autoclaving eliminated completely the pathogenic microbiota without affecting the cast post shape and integrity that could compromise their final fitting.…”
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Updates on the development of vaccines and therapeutic options against rabies by Roshan Arjun Ananda, Hooi-Leng Ser, Vengadesh Letchumanan

“…Further studies on the pathogenic mechanism of RABV and therapeutic approaches are still required to prevent the deathly infection following clinical manifestation. …”
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An updated overview on the bacterial PhoP/PhoQ two-component signal transduction system by Meiqin Mao, Li He, Qingpi Yan

“…Finally, we investigate the coordinated role of the PhoP/PhoQ system in acquiring pathogenic virulence.…”
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Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles by Subhankar Kundu, Kaushik Pal, Arghajit Pyne, Xuefeng Wang

“…Abstract Many micro-particles including pathogens strongly adhere to hosts. It remains elusive how macrophages detach these surface-bound particles during phagocytosis. …”
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Learning predictive signatures of HLA type from T-cell repertoires. by María Ruiz Ortega, Mikhail V Pogorelyy, Anastasia A Minervina, Paul G Thomas, Thierry Mora, Aleksandra M Walczak

“…T cells recognize a wide range of pathogens using surface receptors that interact directly with peptides presented on major histocompatibility complexes (MHC) encoded by the HLA loci in humans. …”
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Genome Architecture and Its Roles in Human Copy Number Variation by Lu Chen, Weichen Zhou, Ling Zhang, Feng Zhang

“…Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. Recent experimental findings have shed light on the links between different genome architectures and CNV mutagenesis. …”
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Using In Silico Methods to Identify Protein Tyrosine Kinase A (PtkA) Homolog in Non-Tuberculous Mycobacteria (NTM) by Swati Jaiswal, Sanjay Kumar

“…Unlike <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>), the causative agent of tuberculosis, NTM species exhibit different pathogenic characteristics and drug resistance mechanisms, making them increasingly relevant in clinical settings. …”
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Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies by Diana-Maria Bunu, Cristian-Eugen Timofte, Manuela Ciocoiu, Mariana Floria, Claudia-Cristina Tarniceriu, Oana-Bogdana Barboi, Daniela-Maria Tanase

“…The aim of this article is to review the available literature about the possible pathogenic mechanisms and determine preventive measures capable of reducing the incidence and severity of the cardiovascular manifestations. …”
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Bridging gaps and leveraging opportunities for One Health: Feedback from the 8th World One Health Congress by Alexandre Caron, Michel de Garine-Wichatitsky, Muriel Figuié, Julie Meunier, Prisca Mugabe, Jakob Zinsstag

“…The One Health approach still needs to go beyond diseases and to embrace a truly holistic definition of health in both its pathogenic and salutogenic components. This broader definition of health should be applied to all human groups with more equity and inclusivity, to non-human animals, as sentient beings, and to ecosystems and the environment in a more integrated way. …”
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Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids by Xiuling Cao, Xiang Wu, Lei Zhao, Ju Zheng, Xuejiao Jin, Xinxin Hao, Joris Winderickx, Shenkui Liu, Lihua Chen, Beidong Liu

“…Our findings identify a conserved cellular component essential for IB maturation and suggest a mechanism by which cells may detoxify the pathogenic protein aggregates through forming mitochondrion-associated IBs.…”
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Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques by Chang Li, Zhenwei Shen, Xiao Li, Jieying Bai, Lin Zeng, Mingyao Tian, Ying Jin Song, Ming Ye, Shouwen Du, Dayong Ren, Cunxia Liu, Na Zhu, Dandan Sun, Yi Li, Ningyi Jin

“…The animals were challenged intramuscularly with pathogenic molecularly cloned SHIV-KB9. Immunogenicity and protective efficacy of vaccines were investigated by measuring IFN-γ levels, monitoring HIV-specific binding antibodies, examining viral load, and analyzing CD4/CD8 ratio. …”
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Cardiovascular Risk Factors in the Antiphospholipid Syndrome by Felipe Freire da Silva, Roger Abramino Levy, Jozélio Freire de Carvalho

“…A major cause of morbidity and mortality in the context of the antiphospholipid syndrome (APS) is the occurrence of thrombotic events. Besides the pathogenic roles of antiphospholipid antibodies (aPL), other risk factors and medical conditions, which are conditions for traditional risk of an individual without the APS, can coexist in this patient, raising their risk of developing thrombosis. …”
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Identification of Contaminated Cells with Viruses, Bacteria, or Fungi by Fourier Transform Infrared Microspectroscopy by V. Erukhimovitch, M. Huleihil, M. Huleihel

“…These results support the potential of developing FTIR microspectroscopy as a simple, reagent free method for identification and discrimination between different tissue infection or contamination with various pathogens.…”
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