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4161
Physicochemical, antioxidant, and antimicrobial study in Nepalese honey
Published 2025-01-01“…Additionally, samples also showed a large zone of inhibition against four pathogens. Besides, the correlation between physicochemical parameters, TFC, TPC, and antioxidant activity was established by using Pearson’s correlation and PCA. …”
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4162
Human stem cell models for Marfan syndrome: a brief overview of the rising star in disease modelling
Published 2025-01-01“…Marfan syndrome is caused by pathogenic variants in FBN1, the gene encoding for the extracellular matrix protein fibrillin-1 which ensembles into microfibrils. …”
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4163
IL-17A and Th17 Cells in Lung Inflammation: An Update on the Role of Th17 Cell Differentiation and IL-17R Signaling in Host Defense against Infection
Published 2013-01-01“…Mice deficient in IL-17 receptor (IL-17R) expression are susceptible to infection by various pathogens. In this review, we summarize the recent advances in unraveling the mechanism behind Th17 cell differentiation, IL-17A/IL-17R signaling, and also the importance of IL-17A in pulmonary infection.…”
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4164
A Novel Subspecies of Didymella acutilobae Causing Leaf Spot in East Asian Hogweed
Published 2024-11-01“…However, the morphological and cultural characteristics of the isolates exhibited somewhat distinct differences from those of D. acutilobae, suggesting that the isolates correspond to a novel subspecies. Pathogenicity tests revealed that the isolates caused leaf spot in East Asian hogweed plants. …”
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4165
Synthesis of Silver Nanoparticles from the Aqueous Extract of Leaves of Ocimum sanctum for Enhanced Antibacterial Activity
Published 2013-01-01“…Such AgNPs stabilized by Tulsi leaf extract were found to have enhanced antimicrobial activity against well-known pathogenic strains, namely Staphylococcus aureus and E. coli.…”
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4166
Efficacy of mesalazine at ulcerative colitis with nutritional failure
Published 2015-03-01“…On the other hand, overweight patients often have more severe course of UC, as it affects important pathogenic processes. This article discusses possible links between trophological status and achievement of clinical remission, as well as between nutritional failure at UC and efficacy of mesalazine monotherapy.Conclusion. …”
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4167
Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in a Child with Myelodysplastic Neoplasm with Complex Karyotype and ETV6 Variant: Challenges in Treatment
Published 2024-04-01“…At diagnosis, the patient showed a complex karyotype with chromosomal abnormalities not yet reported together in the same clone, and likely a pathogenic variant in the ETV6 gene. The patient was treated with HLA-matched sibling HSCT, but unfortunately relapsed after HSCT with clonal cytogenetic evolution. …”
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4168
The Role of Gut Microbiota Modification in Nonalcoholic Fatty Liver Disease Treatment Strategies
Published 2024-01-01“…Therefore, the study of the effect of dysbiosis on the pathogenicity of NAFLD is important. European clinical guidelines state that the best advice for people with NAFLD is to lose weight and improve their lifestyle, but only 40% of people can achieve this goal. …”
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4169
Fetal intracranial hemorrhage in second trimester: An ominous finding even after a normal array
Published 2025-01-01“…However, the whole exome sequencing (WES) identified a heterozygous missense mutation that was considered pathogenic in the COL4A1 (NM_001844.6) gene: c.3715G > A (p.Gly1239Arg). …”
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4170
Irisin regulates oxidative stress and mitochondrial dysfunction through the UCP2-AMPK pathway in prion diseases
Published 2025-02-01“…Abstract Prion diseases are a group of fatal neurodegenerative disorders characterized by the abnormal folding of cellular prion proteins into pathogenic forms. The development of these diseases is intricately linked to oxidative stress and mitochondrial dysfunction. …”
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4171
Clostridium difficile-derived membrane vesicles promote fetal growth restriction via inhibiting trophoblast motility through PPARγ/RXRα/ANGPTL4 axis
Published 2024-12-01“…Clostridium difficile (C. difficile) is associated with fetal birth weight, and its membrane vesicles (MVs) are pathogenic vectors. However, the role of C. difficile and its MVs in FGR remains unclear. …”
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4172
Electrochemical Biosensors 3D Printed by Fused Deposition Modeling: Actualities, Trends, and Challenges
Published 2025-01-01“…This review explores the integration of FDM in fabricating biosensing platforms tailored for clinical diagnostics, emphasizing its role in detecting various biomarkers and viral pathogens. Advances in 3D printing materials, especially the emergence of bespoke conductive filaments, have allowed the production of highly customizable and efficient biosensors. …”
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4173
Natural products in the treatment of diabetic foot infection
Published 2025-01-01“…The growing prevalence of antibiotic-resistant pathogens has reduced the efficacy of conventional treatments, highlighting the need for alternative therapeutic strategies. …”
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4174
The Occurrence of Sequences Identical with Epitopes from the Allergen Pen a 1.0102 Among Food and Non-Food Proteins
Published 2015-03-01“…The rare pentapeptide with the DEERM sequence occurs in proteins not sharing homology with tropomyosins. Pathogenic microorganisms are the most abundant category of organisms synthesizing such proteins.…”
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4175
Biological Effects of Weak Electromagnetic Field on Healthy and Infected Lime (Citrus aurantifolia) Trees with Phytoplasma
Published 2012-01-01“…Phytoplasmas, also known as mycoplasma-like organisms, are wall-less prokaryotes that are pathogens of many plant species throughout the world. …”
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4176
The modification of conventional liposomes for targeted antimicrobial delivery to treat infectious diseases
Published 2025-01-01“…An appraisal of immunological, stimuli-responsive, biomimetic and functionalized liposomes and other novel modifications to conventional liposomes is assimilated in sync with mutations of resistant pathogens.…”
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4177
Antimicrobial Stewardship in Daily Practice: Managing an Important Resource
Published 2014-01-01“…Antimicrobial stewardship is a recent concept that embodies the practical, judicious use of antimicrobials to decrease adverse outcomes from antimicrobials while optimizing the treatment of bacterial infections to reduce the emergence of resistant pathogens. The objectives of the present statement are to illustrate the principles of antimicrobial stewardship and to offer practical examples of how to make antimicrobial stewardship part of everyday hospital and outpatient practice. …”
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4178
Cerebrovascular Complications in Bacterial Meningitis
Published 2025-01-01“…Streptococcus pneumoniae and Staphylococcus aureus are the primary causative pathogens leading to these complications. The pathophysiological mechanisms have not completely been elucidated but involve vasculitis, endothelial dysfunction, hypercoagulability, aggregation, and complement activation. …”
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4179
Grimontia hollisae Sepsis in a 9‐Month‐Old Female Infant: A Case Report
Published 2025-01-01“…Prompt diagnosis through blood culture and targeted antibiotic therapy ensured recovery, emphasizing the need for increased awareness, enhanced diagnostic tools, and active monitoring of emerging pathogens in tropical and resource‐limited regions. …”
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4180
Geographic variation in abundance and diversity of Acinetobacter baumannii Vieuvirus bacteriophages
Published 2025-01-01“…IntroductionProphages play a crucial role in the genomic diversity of Acinetobacter baumannii, contributing to its pathogenicity and adaptation.MethodsIn this study, we induced and sequenced seven prophages from five isolates of A. baumannii. …”
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