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  1. 4141

    Pathogenesis of Chronic Urticaria: An Overview by Sanjiv Jain

    Published 2014-01-01
    “…An increasing recognition of chronic urticaria as an immune mediated inflammatory disorder related to altered cytokine-chemokine network consequent to immune dysregulation resulting from disturbed innate immunity is emerging as yet another pathogenic explanation. It is likely that these different pathomechanisms are interlinked rather than independent cascades, acting either synergistically or sequentially to produce clinical expression of chronic urticaria. …”
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  2. 4142

    DIAGNOSIS AND THERAPEUTIC MANAGEMENT OF COMPLICATED MIDDLE EAR CHOLESTEATOMA. A NARRATIVE REVIEW by Marius Cristian Mârțu, Alexandru Stingheriu, Oana Aștefanei, Iustin Iațentiuc, Ioana Mârțu, Oana Bitere-Popa

    Published 2024-12-01
    “…However, these advances have also contributed to the emergence of pathogens with heightened virulence and resistance to antibiotics, posing new therapeutic challenges. …”
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  3. 4143

    Neuropsychiatric disorders in Wilson’s disease: literature review by S. Galnaitytė, A. Musneckis

    Published 2023-10-01
    “… Wilson’s disease is a rare autosomal recessive disease due to the pathogenic mutations in the ATP7B gene that causes impaired copper excretion in the liver and its accumulation in tissues and organs. …”
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  4. 4144

    Potential of Peptides as Inhibitors and Mimotopes: Selection of Carbohydrate-Mimetic Peptides from Phage Display Libraries by Teruhiko Matsubara

    Published 2012-01-01
    “…However, it is very difficult to prepare a diverse range of sugar derivatives by chemical synthesis or by the isolation of natural products. In addition, the pathogenic capsular polysaccharides of bacteria are carbohydrate antigens, for which a safe and efficacious method of vaccination is required. …”
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  5. 4145
  6. 4146

    Skin Acute Wound Healing: A Comprehensive Review by Luis Cañedo-Dorantes, Mara Cañedo-Ayala

    Published 2019-01-01
    “…The following target of the inflammatory phase, led by the peripheral blood mononuclear cells, is to eliminate the pathogens and clean the wound. Once this is completed, the inflammatory phase is resolved and homeostasis is restored. …”
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  7. 4147

    Influenza A Virus Entry: Implications in Virulence and Future Therapeutics by Emily Rumschlag-Booms, Lijun Rong

    Published 2013-01-01
    “…This broad tropism makes highly pathogenic influenza A strains, such as H5N1, potentially dangerous to humans if they gain the ability to jump from an animal reservoir to humans. …”
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  8. 4148

    Vibrio parahaemolyticus: The protagonist of foodborne diseases by Vengadesh Letchumanan, Ke-Yan Loo, Jodi Woan-Fei Law, Sunny Hei Wong, Bey-Hing Goh, Nurul-Syakima Ab Mutalib, Learn-Han Lee

    Published 2019-07-01
    “…Of all the foodborne pathogens, Vibrio parahaemolyticus has been accounted for many outbreaks globally and still at rise even with proper management methods. …”
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  9. 4149

    Novel Phenotype in Unbalanced 7;9 Translocation with Critical Incidental Finding by Julie Fischer, Luis Rohena

    Published 2022-01-01
    “…This testing revealed an incidental pathogenic heterozygous KCNH2 deletion, which is associated with long QT-syndrome type II. …”
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  10. 4150

    Charge de travail et stress professionnel : deux facettes d’une même réalité ? by Sandrine Cazabat, Béatrice Barthe, Nadine Cascino

    Published 2008-05-01
    “…These results show evidence that the establishment of a regulatory process that is both adaptive and pathogenic. In order to handle a work overload, nurses isolated themselves in order to accomplish their duties and this isolation has an impact on their health.…”
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  11. 4151

    The Origin of Individual Differences in the Course and Severity of Diseases by Sergey N. Rumyantsev

    Published 2006-01-01
    “…In a population predilected to a relevant pathogenic agent, individuals can be conveniently divided into three categories: totally resistant organisms that contain no susceptible structures and are not affected; mildly susceptible organisms in which a few foci appear and in which the disease runs a benign course; organisms in which the number of constitutionally susceptible structures is high and the disease develops in a severe form. …”
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  12. 4152

    Mathematical Analysis of the Role of Treatment and Vaccination in the Management of the HIV/AIDS and Pneumococcal Pneumonia Co-Infection by Michael Byamukama, Martin Karuhanga, Damian Kajunguri

    Published 2025-01-01
    “…Concomitant infections by two or more pathogens are on upsurge and among these is the interplay between HIV/AIDS and pneumococcal pneumonia infections. …”
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  13. 4153

    The Use of Different Image Recognition Techniques in Food Safety: A Study by Rijwan Khan, Santosh Kumar, Niharika Dhingra, Neha Bhati

    Published 2021-01-01
    “…In order to avoid foodborne disease and ensure food security, fast and effective detection of pathogenic microorganisms is crucial for public safety biomonitoring. …”
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  14. 4154

    Effects of Mussel Peptides on Growth and Development and Microbial Community Structure of the Thick-Shelled Mussel Mytilus coruscus Plantigrades by Qian LIN, Zheng LI, Jinlong YANG, Fan MA, Xiao LIANG

    Published 2025-02-01
    “…They can promote the growth and development of aquatic organisms, enhance resistance to pathogenic bacteria, and improve the absorption and utilization rate of feed to increase the output of aquatic products. …”
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  15. 4155

    Humanistic nursing and nursing ethics of infection and infectious diseases (传染与感染性疾病人文护理及护理伦理) by TIAN Yiying (田艺莹), LI Jiayue (李佳玥), ZHANG Bei (张北), QI Shasha (齐莎莎), GAO Xiaoming (高晓明), REN Yuanyuan (任媛媛), JIANG Mingyue (姜明月)

    Published 2023-10-01
    “…Nurses should pay more attention to nursing of patients with infections and infectious diseases, and carry out effective hygiene management and infection care to minimize the infection rate of infectious disease pathogens. This article briefly analyzed the ethical issues of infection and infectious disease care, and explored specific nursing methods for infection and infectious diseases, aiming to provide assistance and reference for modern infection and infectious disease care in China. …”
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  16. 4156

    Development of lateral flow immunochromatographic assay with Anti-Pythium insidiosum antibodies for point-of-care testing of vascular pythiosis by Panwad Tongchai, Ati Burassakarn, Nattapong Langsiri, Navaporn Worasilchai, Ariya Chindamporn

    Published 2025-01-01
    “…Abstract The pathogenic oomycete Pythium insidiosum causes a fatal infectious illness known as pythiosis, impacting humans and certain animals in numerous countries in the tropics and subtropics. …”
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  17. 4157

    Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>) by Vladimir A. Marchenko, Irina N. Zhilinskaya

    Published 2024-12-01
    “…Thus, influenza A viruses, including subtypes A(H1N1)pdm09, A(H3N2), as well as highly pathogenic avian influenza viruses, can infect the vascular endothelium, leading to activation and subsequent dysfunction of these cells. …”
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  18. 4158

    Congenital Glaucoma: a Novel Ocular Manifestation of Hajdu-Cheney Syndrome by L. Swan, G. Gole, V. Sabesan, J. Cardinal, D. Coman

    Published 2018-01-01
    “…We describe a hitherto undescribed missense mutation that is predicted to be pathogenic, with functional characterization remaining to be performed. …”
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  19. 4159

    Litomosoides sigmodontis microfilariae-induced eosinophil ETosis is dependent on the canonical inflammasome pathway by Alexandra Ehrens, Benjamin Lenz, Celia Nieto-Pérez, Eicke Latz, Florian I. Schmidt, Achim Hoerauf, Marc P. Hübner

    Published 2025-01-01
    “…While bacteria-induced ETosis has been linked to the non-canonical inflammasome pathway, the role of the inflammasome activation during ETosis in response to extracellular pathogens has not been investigated. The current study demonstrates that microfilariae (MF) of the rodent filarial nematode Litomosoides sigmodontis induce eosinophil ETosis via the canonical inflammasome pathway. …”
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  20. 4160

    Generation of a human induced pluripotent stem cell lines (UKJi003-A) from a patient with Fabry disease and healthy donor (UKJi004-A) by Mohamed M. Bekhite, Sascha Hübner, Tom Kretzschmar, Claudia Backsch, Anja Weise, Elisabeth Klein, Jürgen Bogoviku, Julian Westphal, P. Christian Schulze

    Published 2025-02-01
    “…Fabry disease (FD, OMIM #301500) is a rare metabolic disorder, X-linked glycosphingolipidosis that is characterized by pathogenic mutations in the GLA (Galactosidase Alpha) gene (OMIM *300644) that result in reduced α-galactosidase A (α-GAL) activity and accumulation of globotriaosylceramide (Gb3) in tissues and organs. …”
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