Chemical Characterization and Antimicrobial Activity of Essential Oils and Nanoemulsions of <i>Eugenia uniflora</i> and <i>Psidium guajava</i> by Rebeca Dias dos Santos, Breno Noronha Matos, Daniel Oliveira Freire, Franklyn Santos da Silva, Bruno Alcântara do Prado, Karolina Oliveira Gomes, Marta Oliveira de Araújo, Carla Azevedo Bilac, Letícia Fernandes Silva Rodrigues, Izabel Cristina Rodrigues da Silva, Lívia Cristina Lira de Sá Barreto, Claudio Augusto Gomes da Camara, Marcilio Martins de Moraes, Guilherme Martins Gelfuso, Daniela Castilho Orsi

“…The time–growth inhibition assay also suggests the effectiveness of the NE against the tested pathogens <i>S. aureus</i> and <i>E. coli</i>, highlighting its potential as a novel alternative therapeutic agent.…”
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Hearing Phenotypes of Patients with Hearing Loss Homozygous for the GJB2 c.235delc Mutation by Chang Guo, Sha-Sha Huang, Yong-Yi Yuan, Ying Zhou, Ning Wang, Dong-Yang Kang, Su-Yan Yang, Xin Zhang, Xue Gao, Pu Dai

“…Patients with the same pathogenic mutations may exhibit various hearing loss phenotypes. …”
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Detection of genetic determinants of potentially oncogenic representatives of the intestinal microbiota as biomarkers of colorectal cancer by Viktoriya N. Shumilova, Artemij E. Goncharov, Daniil V. Azarov, Stanislav I. Sitkin, Elgudzha L. Latariya, Batyrbek I. Aslanov, Mikhail A. Bobrakov, Rustem E. Topuzov

“…An association was found between CRC and the presence of the Bacteroides fragilis fragilisin gene (OR 7.00; 95% CI: 2.55–22.50; p 0.001), species-specific genes of the periodontal pathogenic microorganisms Fusobacterium nucleatum (OR 5.61; 95% CI: 2.87–11.30; p 0.001) and Porphyromonas gingivalis (OR 16.3; 95% CI: 4.33–106.00; p 0.001), the clbB gene of pks pathogenicity island of the Enterobacteria (OR 3.44; 95% CI: 1.39–8.51; p = 0.010). …”
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Niobium Uptake and Release by Bacterial Ferric Ion Binding Protein by Yanbo Shi, Ian Harvey, Dominic Campopiano, Peter J. Sadler

“…The possibility of designing niobium-based antibiotics which block iron uptake by pathogenic bacteria is discussed.…”
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Genome rearrangements in neurodevelopmental disorders of the central nervous system: origins, genomic mechanisms, functional and clinical consequences. Review article by V. Kučinskas, E. Preikšaitienė, L. Ambrozaitytė, L. Cimbalistienė, A. Utkus

“…In our research, the detection of chromosomal aberrations by molecular karyotyping and whole exome sequencing capable of uncovering pathogenic variants in any of the human genes were the main technologies used to identify the molecular causes of intellectual disability. …”
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Recent Advances in Our Understanding of HLA-G Biology: Lessons from a Wide Spectrum of Human Diseases by Fabio Morandi, Roberta Rizzo, Enrico Fainardi, Nathalie Rouas-Freiss, Vito Pistoia

“…However, HLA-G can be expressed de novo at high levels in several pathological conditions, including solid and hematological tumors and during microbial or viral infections, leading to the impairment of the immune response against tumor cells or pathogens, respectively. On the other hand, the loss of HLA-G mediated control of the immune responses may lead to the onset of autoimmune/inflammatory diseases, caused by an uncontrolled activation of the immune effector cells. …”
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Examination of Molecular Effects of MYLK Deletion in a Patient with Extensive Aortic, Carotid, and Abdominal Dissections That Underlie the Genetic Dysfunction by Sarah K. Macklin, Katelyn A. Bruno, Charitha Vadlamudi, Haytham Helmi, Ayesha Samreen, Ahmed N. Mohammad, Stephanie Hines, Paldeep S. Atwal, Thomas R. Caulfield

“…Through a combined multiomic approach of clinical, functional, and protein informatics, we arrive at a data fusion for determination of pathogenicity embedded within the genetic code for this particular genetic variant, which, as a platform, continues to broaden its scope across the field of variants of uncertain significance classification.…”
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Septic Systems and Springs Water Quality: An Overview for Florida by Mary Lusk, Andrea Albertin, Whitney Elmore, William Lester, James Moll

“… Wastewater carries pathogens, nutrients (nitrogen and phosphorus), and trace organic chemicals that may be harmful to human health and ecosystem functioning. …”
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Nanoparticles: a promising tool against environmental stress in plants by Xu Zhou, Ahmed H. El-Sappah, Ahmed H. El-Sappah, Amani Khaskhoussi, Qiulan Huang, Amr M. Atif, Mohamed A. Abd Elhamid, Muhammad Ihtisham, Mohamed F. Abo El-Maati, Salma A. Soaud, Walid Tahri

“…NPs may feed nutrients to plants, prevent plant diseases and pathogens, and detect and monitor trace components in soil by absorbing their signals. …”
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Risk factors of pan-vascular diseases and their interactions by Wei Shulin, Zhou Yongwen, Xu Suowen, Weng Jianping

“…By elucidating the independent or shared pathogenic mechanisms of multiple risk factors, this review summarizes the important evidence for early intervention, comprehensive management, muti-targeted therapies, and ultimately the reduction or delay of the occurrence and pregression of pan-vascular disease.…”
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Empyema Necessitans Complicating Pleural Effusion Associated with Proteus Species Infection: A Diagnostic Dilemma by M. S. Yauba, H. Ahmed, I. A. Imoudu, M. O. Yusuf, H. U. Makarfi

“…Empyema necessitatis is a rare condition that can be caused by Gram negative bacterial pathogens like Proteus species.…”
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IgG4-Related Disease Presenting as Isolated Scleritis by Eran Berkowitz, Ella Arnon, Alona Yaakobi, Yuval Cohen, Beatrice Tiosano

“…This case highlights the significance of IgG4-RD in the differential diagnosis of scleritis and raises the question as to whether various organs affected by IgG4-RD may have different underlying pathophysiological mechanisms in which pathogenic T cells play a role.…”
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Importance of Lipopolysaccharide and Cyclic β-1,2-Glucans in Brucella-Mammalian Infections by Andreas F. Haag, Kamila K. Myka, Markus F. F. Arnold, Paola Caro-Hernández, Gail P. Ferguson

“…Brucella species persist as intracellular pathogens that manage to effectively evade recognition by the host's immune system. …”
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Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications by Shinji Uemoto, Kazue Ozawa, Hiroto Egawa, Yasutsugu Takada, Hiroshi Sato, Satoshi Teramukai, Mureo Kasahara, Kohei Ogawa, Masako Ono, Kenji Takai, Masanori Fukushima, Kayo Inaba, Koichi Tanaka

“…In Groups I and II, both approaches showed a strong upward deviation from pretransplant status upon posttransplant infection, indicating an enhanced clearance of pathogens. In Group III, in contrast, both approaches showed a clear downward deviation from preoperative status, indicating deficient cytotoxicity. …”
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Coleopteran Antimicrobial Peptides: Prospects for Clinical Applications by Monde Ntwasa, Akira Goto, Shoichiro Kurata

“…AMPs act directly against pathogens and have both wound healing and antitumor activities. …”
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The Effects of TLR Activation on T-Cell Development and Differentiation by Bo Jin, Tao Sun, Xiao-Hong Yu, Ying-Xiang Yang, Anthony E. T. Yeo

“…Invading pathogens have unique molecular signatures that are recognized by Toll-like receptors (TLRs) resulting in either activation of antigen-presenting cells (APCs) and/or costimulation of T cells inducing both innate and adaptive immunity. …”
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Gut microbiome diversity as adjuvant marker for immune function by Mahdaleny, Febriana Catur Iswanti

“…Mucin, bacterial polysaccharides, and protein combine to form a unique mucosal biofilm that serves as a home for a variety of commensal and pathogenic organisms in the host. Maintaining proper mucosal barrier function is vital for both GI and systemic health. …”
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Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body? by Pierre Olivier Lang, Dimitrios Samaras

“…Evidence that VitD affects clearance of selected pathogens is supported by epidemiological and clinical data, while its coadministration with influenza vaccine in mice enhanced both mucosal and systemic antibody responses. …”
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Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection by Bryan E. Hart, Richard I. Tapping

“…Toll-like receptors (TLRs) have emerged as an essential family of innate immune pattern recognition receptors which play a pivotal role in host defense against microbes, including pathogenic strains of mycobacteria. This paper will highlight studies which have uncovered the association of specific TLR gene polymorphisms with leprosy or tuberculosis: two important diseases resulting from mycobacterial infection. …”
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Advancing veterinary vaccines design through trained immunity insights by Xin Wang, Xin Wang, Xin Wang, Xin Wang, Guohua Yu, Guohua Yu, Guohua Yu

“…While implementation challenges exist, including individual response variations and safety considerations, trained immunity-based vaccines show potential for providing broader protection against emerging pathogens. This approach could revolutionize veterinary vaccinology by offering enhanced efficacy and cross-protection against heterologous infections, particularly valuable for zoonotic disease control.…”
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