The Antibacterial Effect of Tinospora Cordifolia (Guduchi) and Its Role in Combating Antimicrobial Resistance by Kavitha EZHILARASU, Anand KASIRANJAN, Shanmuga PRIYA, Anand KAMARAJ

“…Methods: Using the agar well diffusion method, Tinospora cordifolia extracts (aqueous, chloroform, and ethanol) were tested for their antibacterial effectiveness against 30 MDR pathogens, and the 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay was used to determine the minimal inhibitory concentration. …”
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Leclercia adecarboxylata Bacteremia in a Patient with Ulcerative Colitis by Amir Kashani, Morteza Chitsazan, Kendrick Che, Roger C. Garrison

“…The human GI tract is known to harbor this rarely pathogenic microorganism. There are only a few case reports of bacteremia with this microorganism; the majority are either polymicrobial or associated with immunocompromised patients. …”
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Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro by Emily Chen, Bruna Benso, Dalia Seleem, Luiz Eduardo Nunes Ferreira, Silvana Pasetto, Vanessa Pardi, Ramiro Mendonça Murata

“…Thus, this study evaluated the modulatory effects of curcumin on major virulence factors associated with the pathogenicity of C. albicans. The minimum inhibitory concentration (MIC) of curcumin against C. albicans (SC5314) was determined. …”
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Bioactive Characteristics of Wild Berberis vulgaris and Berberis crataegina Fruits by Arzu Yaşar Eroğlu, Özlem Çakır, Mustafa Sağdıç, Enes Dertli

“…The water extracts of the Berberis fruits were tested against important foodborne pathogenic bacteria as potential antimicrobials. The extracts inhibited the growth of Bacillus cereus, Salmonella typhimurium, Yersinia enterocolitica, and Staphylococcus aureus at significant rates. …”
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Production of Prodigiosin Using Tannery Fleshing and Evaluating Its Pharmacological Effects by C. Sumathi, D. MohanaPriya, S. Swarnalatha, M. G. Dinesh, G. Sekaran

“…Therapeutic efficacy was assessed by in vitro anticancer studies. Among the pathogenic bacteria Pseudomonas aeruginosa was most susceptible at the lowest concentration followed by Salmonella typhi. …”
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Antifungal and Antibacterial Activity of Aqueous and Ethanolic Extracts of Different <i>Rosa rugosa</i> Parts by Žaneta Maželienė, Jolita Kirvaitienė, Kamilė Kaklauskienė, Rasa Volskienė, Asta Aleksandravičienė

“…With the rising incidence of drug-resistant pathogens, focus should be placed on biologically active compounds derived from plant species used in herbal medicine, as these compounds may provide a new source of antifungal and antibacterial activities. …”
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Adipocytokines in Rheumatoid Arthritis: The Hidden Link between Inflammation and Cardiometabolic Comorbidities by Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Cipriani, Roberto Giacomelli

“…Remarkably, some well-known pathogenic proinflammatory mediators in RA, such as interleukin-1β (IL-1β) and tumor necrosis factor (TNF), may play a pivotal role in the development of CVD. …”
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Genetic Testing Distinguishes Multiple Chondroid Chordomas with Neuraxial Bone Metastases from Multicentric Tumors by Hiroshi Kobayashi, Masahiro Shin, Naohiro Makise, Aya Shinozaki-Ushiku, Masachika Ikegami, Yuki Taniguchi, Yusuke Shinoda, Shinji Kohsaka, Tetsuo Ushiku, Katsutoshi Oda, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano, Sakae Tanaka

“…Next-generation sequencing revealed that these lesions harbored a common somatic mutation in epidermal growth factor receptor (EGFR), c.3617A>C, which is not considered a pathogenic chordoma mutation, thus indicating that these lesions were not multicentric but rather multiple metastatic tumors. …”
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Idiopathic CRMO and MEFV Gene Variant Alleles: Is There Any Relationship? by Farhad Salehzadeh, Hassan Anari, Sepehr Sarkhanloo

“…Blood samples of patients, who diagnosed as childhood idiopathic CRMO by imaging and pathologic study from June 2011 until September 2018, have been screened for the 12 common pathogenic variants of MEFV gene mutations. Result. …”
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Hepatic injury and metabolic perturbations in mice exposed to perfluorodecanoic acid revealed by metabolomics and lipidomics by Lvyun Sun, Shuling He, Jiali Chen, Amei Su, Qiuyao Mao, Wenyuan Zhang, Ying Pan, Jiaqian Hu, Disheng Feng, Yang Ouyang

“…However, research on the effects of PFDA exposure on organism metabolism and related pathogenic mechanisms is severely lacking. In this study, serum and liver samples of C57BL/6 J mice exposed to different doses of PFDA were analyzed by UPLC-HRMS-based metabolomics and lipidomics techniques. …”
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A Pilot Study of Exosome Proteomic Profiling Reveals Dysregulated Metabolic Pathways in Endometrial Cancer by Feras Kharrat, Valeria Capaci, Andrea Conti, Valentina Golino, Pietro Campiglia, Nour Balasan, Michelangelo Aloisio, Danilo Licastro, Lorenzo Monasta, Federica Caponneto, Antonio Paolo Beltrami, Federico Romano, Giovanni di Lorenzo, Giuseppe Ricci, Blendi Ura

“…<b>Background/Objectives</b>: Endometrial cancer (EC) is the second most frequent gynecological malignant tumor in postmenopausal women. Pathogenic mechanisms related to the onset and development of the disease are still unknown. …”
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Study on fungal contaminants in aborted calves of cattle herds in Iran by Samaneh Eidi, Hesam A. Seifi, Soheil Sadr, Hamideh Zeinali

“…., were identified, indicating a diverse range of pathogens affecting calves. The specificity of fungal contaminants in certain organs, such as C. neoformans, Rhodotorula spp. and Trichosporon spp., highlighted the organ's microenvironment as a potential factor influencing fungal growth. …”
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Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258 by Prashantkumar Siddappa Chakra, Aishwarya Banakar, Shriram Narayan Puranik, Vishwas Kaveeshwar, C. R. Ravikumar, Devaraja Gayathri

“…Furthermore, the synthesized nanoparticles displayed significant antibacterial activity against selected human pathogens, with the biggest inhibition zone observed against Staphylococcus aureus (22 ± 0.57 mm) and the smallest inhibition zone observed against Salmonella enterica serovar typhi (3 ± 1 mm). …”
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In vitro long-term exposure to chlorhexidine or triclosan induces cross-resistance against azoles in Nakaseomyces glabratus by Kathrin Spettel, Dominik Bumberger, Richard Kriz, Sarah Frank, Madita Loy, Sonia Galazka, Miranda Suchomel, Heimo Lagler, Athanasios Makristathis, Birgit Willinger

“…Abstract Background Topical antiseptics are crucial for preventing infections and reducing transmission of pathogens. However, commonly used antiseptic agents have been reported to cause cross-resistance to other antimicrobials in bacteria, which has not yet been described in yeasts. …”
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Unique Case Report of a Meningeal Sarcoma Arising during Ongoing Treatment for Progressing Intraparenchymal Glioma by Richard A. Peterson, Bhavani Kashyap, Pamala A. Pawloski, Anna C. Forsberg, Leah R. Hanson

“…Genetic testing revealed no pathogenic mutation in the TP53 gene. Ultimately, treatment was unsuccessful and the patient succumbed to glioma and sarcoma within 2 years of initial diagnosis. …”
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Biological properties of coronaviruses of farm, domestic animals and birds: comparative characterization of pathology they induce (review) by Kh. Z. Gaffarov, A. I. Yarullin, V. G. Gumerov, I. G. Karimullina

“…Members of the family Coronaviridae are characterized by the fact that they infect a wide range of animals and birds with expressed species-limited  pathogenicity.  One more coronavirus specificity involves their ability to simultaneously affect more than one organ. …”
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The relationship between kidney disease and mitochondria: a bibliometric study by Jueyi Mao, Cuifang Li, Feifeng Wu, Yang Wang, Junquan Zhu, Chuan Wen

“…We found that research in this field has shifted from disease-level studies to mechanism-based studies, with the most prominent disease being diabetic nephropathy and the most prominent pathogenic mechanism being related to mitochondrial ROS production.Conclusion The bibliometric analysis provided a comprehensive understanding of the progress of research on the role of mitochondria in kidney disease, enriching the review literature in this field.…”
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Microbial and Inflammatory Salivary Biomarkers of Periodontal Diseases by Aram Mohammed Sha, Hayder Raad Abdulbaqi, Syed Saad Bin Qasim

“…In addition to periodontal pathogens, interest in salivary biomarkers of periodontal disease is increasing, and a number of biomarkers have the potential to be accurate indicators of disease and the effectiveness of therapy. …”
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Tinea manuum: a 5 year retrospective study of demographic data, clinical characteristics, and treatment outcomes by Panittra Suphatsathienkul, Pattriya Jirawattanadon, Lalita Matthapan, Waranyoo Prasong, Chatisa Panyawong, Akkarapong Plengpanich, Sumanas Bunyaratavej, Charussri Leeyaphan

“…Among 50 positive cultures, dermatophytes accounted for 86% and nondermatophytes for 14%, with Trichophyton rubrum (54%) and Trichophyton mentagrophytes complex (24%) being the most frequent pathogens. Systemic antifungal treatment was administered to 57% of patients, with a mycological cure rate of 56.4%. …”
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Granulomatous Lung Disease Requiring Mechanical Ventilation Induced by a Single Application of Oxaliplatin-Based Chemotherapy for Colorectal Cancer: A Case Report by Dane Wildner, Frank Boxberger, Axel Wein, Kerstin Wolff, Heinz Albrecht, Gudrun Männlein, Rolf Janka, Kerstin Amann, Jürgen Siebler, Werner Hohenberger, Markus F. Neurath, Richard Strauß

“…The histological workup revealed distinct granulomatous inflammation, but no microbial pathogens were to be found. Thereupon, a drug-induced reaction to chemotherapy was suspected and high-dose steroid treatment initiated. …”
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