Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review by Linda Tong Pao, Mohamed Tashani, Catherine King, Harunor Rashid, Ameneh Khatami

“…There appears to be an association between attendance at mass gatherings and the acquisition of some AMR phenotypes and genotypes in some significant human pathogens, including <i>E. coli</i> and <i>S. pneumoniae</i>.…”
Get full text

Physical-Chemical Characterization of Fruit Harvested at Different Maturity Stages of Grafted Yellow Pitahaya (<i>Selenicereus megalanthus</i> Haw.) by Jessica Sanmiguel, Valdemar Andrade, Yadira Vargas-Tierras, Iván Samaniego, Fernando Paredes-Arcos, Wilson Vásquez-Castillo, William Viera-Arroyo

“…The <i>S. megalanthus</i> grafting technique is a promising technology for sustainable production because it reduces pesticide use by combatting soil pathogens and not modifying fruit quality.…”
Get full text

Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model by Wei Li, Xue Wang, Keyuan Chen, Yaohong Zhu, Guiyan Yang, Yipeng Jin, Jiufeng Wang

“…Moreover, WB600/ZD pretreatment facilitated the growth of beneficial bacteria such as Lachnospiraceae, Butyricicoccus, Eubacterium_xylanophilum, and Clostridia_UCG-014 while decreasing the abundance of pathogenic bacteria such as Escherichia-Shigella and Salmonella (P < 0.05). …”
Get full text

Effects of Red Clover Isoflavones on Growth Performance, Immune Function, and Cecal Microflora of Mice by Rongrong Guo, Xuqin Song, Xiaodie Li, Cheng Zeng, Ying Chen, Chunjie Li, Jian Yang, Deyuan Ou

“…RCIs can increase the diversity of beneficial bacteria such as <i>Bacteroidaceae</i>, <i>Muribaculaceae</i>, and <i>Akkermansiaceae</i>, and reduced the pathogenic <i>Staphylococcaceae</i>. Therefore, supplementing the diet with RCIs results in improved growth performance and notable alterations in the cecal microbiota in mice, and has potential applications as a feed additive to improve livestock production.…”
Get full text

The adoption of biosecurity measures and its influencing factors in Bangladeshi layer farms by Mohammad Jahangir Alam, Ismat Ara Begum, Md. Abdullah Al Mamun, Md. Asif Iqbal, Andrew M. McKenzie

“…Abstract Developing nations like Bangladesh are particularly vulnerable to poultry diseases, notably Highly Pathogenic Avian Influenza. Adopting biosecurity approaches that assist farms in disease control and prevention can decrease the industry-wide dissemination of infectious diseases. …”
Get full text

Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins by A. Catania, G. Colombo, C. Rossi, A. Carlin, A. Sordi, C. Lonati, F. Turcatti, P. Leonardi, P. Grieco, S. Gatti

“…Several properties of α-melanocyte stimulating hormone (α-MSH) suggested that it could be a natural antimicrobial peptide. α-MSH is a primordial peptide that appeared during the Paleozoic era, long before adaptive immunity developed and, like natural antimicrobial molecules, is produced by barrier epithelia, immunocytes, and within the central nervous system. α-MSH was discovered to have antimicrobial activity against two representative pathogens, Staphylococcus aureus and Candida albicans. …”
Get full text

Overexpression of the Synthetic Chimeric Native-T-phylloplanin-GFP Genes Optimized for Monocot and Dicot Plants Renders Enhanced Resistance to Blue Mold Disease in Tobacco (N. taba... by Dipak K. Sahoo, Sumita Raha, James T. Hall, Indu B. Maiti

“…Our results demonstrate that in vivo expression of a synthetic fused native-phylloplanin-GFP gene in plants can potentially achieve natural protection against microbial plant pathogens, including P. tabacina in tobacco.…”
Get full text

HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response by Mudan Lu, Shanshan Yu, Wei Xu, Bo Gao, Sidong Xiong

“…HMGB1, which may act as a proinflammatory mediator, has been proposed to contribute to the pathogenesis of multiple chronic inflammatory and autoimmune diseases including systemic lupus erythematosus (SLE); however, the precise mechanism of HMGB1 in the pathogenic process of SLE remains obscure. Method. The expression of HMGB1 was measured by ELISA and western blot. …”
Get full text

Modeling the Distribution of Dominant Hard Ticks in Southeastern Coastal Areas of the Caspian Sea by Sedighe Nabian, Elahe Ebrahimzadeh, Abbas Farahi, Ahmad Ali Hanafi-Bojd

“… Background: Ticks are hematophagous arthropods that have direct and indirect effects on hosts, including the trans­mission of pathogens. An environmental suitability study of some vector species of hard ticks was conducted using the MaxEnt model in the south-eastern region of the Caspian Sea in Iran. …”
Get full text

Intestinal Mucosal Barrier Is Injured by BMP2/4 via Activation of NF-κB Signals after Ischemic Reperfusion by Kang Chen, Wei Xie, Binyu Luo, Weidong Xiao, Daniel H. Teitelbaum, Hua Yang, Kebin Zhang, Chaojun Zhang

“…On the basis of these data, we conclude that BMP2/4 may act as the pathogenic basis for intestinal mucosal barrier dysfunction when the intestines suffer an I/R injury. …”
Get full text

Spent Coffee Ground and Its Derivatives as Soil Amendments—Impact on Soil Health and Plant Production by Yi Hu, Juan Li, Yiping Wu, Dongdong Zhang, Zhiyong Qi, Rui Yang

“…SCG and its derivatives may be used as biocontrol agents for weeds, soil-borne pathogens, and pests. Novel bio-organic fertilizers based on SCG have also been developed. …”
Get full text

Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis by Jingyi Hou, Yi Ouyang, Haiquan Deng, Zhong Chen, Bin Song, Zhongyu Xie, Peng Wang, Jinteng Li, Weiping Li, Rui Yang

“…Our study found that differentially expressed genes in the MAPK signaling, rheumatoid arthritis, and p53 signaling pathways may help to explain the pathogenic mechanism of RA and lead to therapeutic RA SMSC applications.…”
Get full text

Physiological and Antagonistic Properties of Pichia kluyveri for Curative and Preventive Treatments Against Post-Harvest Fruit Fungi by Maxwell Mewa Ngongang, Heinrich Wilbur Du Plessis, Chidi Silas Boredi, Ucrecia Faith Hutchinson, Karabo Seteno Obed Ntwampe, Vincent Ifeanyi Okudoh, Neil Paul Jolly

“…Similarly, preventive application on grapes was also effective against the fungal pathogens studied. In general, the antagonistic responses were both fungus- and treatment- (curative and preventive) dependent. …”
Get full text

Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…Periodontitis is an inflammatory disease caused by pathogenic microorganisms and characterized by the destruction of the periodontium. …”
Get full text

Faecalibacterium prausnitzii: A Next-Generation Probiotic in Gut Disease Improvement by Xiaoya He, Shuyang Zhao, Yan Li

“…The researchers are paying more attention to the role of gut commensal bacteria in health development beyond the classical pathogens. It has been widely demonstrated that dysbiosis, which means the alternations of the gut microbial structure, is closely associated with development of intestinal chronic inflammation-related diseases such as inflammatory bowel disease (IBD), and even infectious diseases including bacterial and viral infection. …”
Get full text

Antagonistic Activity of Extremophilic Bacteria Against Phytopathogens in Agricultural Crops by Lyudmila K. Asyakina, Yuliya R. Serazetdinova, Anna S. Frolova, Natalya V. Fotina, Olga A. Neverova, Andrey N. Petrov

“…The resulting consortium can be used as a biopesticide since it is highly effective in protecting wheat from Alternaria and Fusarium pathogens.…”
Get full text

New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…The host’s immunity plays a central role in the course of the infection; therefore, it may not be clinically manifest or may produce various benign or malignant lesions. The pathogenic mechanisms are complex and incompletely elucidated. …”
Get full text

Gain-of-Function Mutations in STAT1: A Recently Defined Cause for Chronic Mucocutaneous Candidiasis Disease Mimicking Combined Immunodeficiencies by Sanem Eren Akarcan, Ezgi Ulusoy Severcan, Neslihan Edeer Karaca, Esra Isik, Guzide Aksu, Mélanie Migaud, Ferda Evin Gurkan, Elif Azarsiz, Anne Puel, Jean-Laurent Casanova, Necil Kutukculer

“…Chronic-recurrent infections with different pathogens leading to significant morbidity suggested combined immunodeficiency, CMC, or Mendelian susceptibility to mycobacterial diseases. …”
Get full text

Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…In addition, the genomic epidemiological study showed that AB073-like strains were successful pathogens widespread in various geographic locations and clinical sources. …”
Get full text

Concomitant of Pulmonary Hydatid Cyst and Aspergilloma: A Rare Coinfection by Zahra Zareshahrabadi, Bahador Sarkari, Nadereh Shamsolvaezin, Bizhan Ziaian, Alireza Tootoonchi, Reza Shahriarirad, Kamiar Zomorodian

“…Further attention is recommended to control fungal pathogens during pulmonary hydatidosis. The coexistence of aspergilloma should always be kept in mind for the better management of CE.…”
Get full text