Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses by Lyubomir A. Dourmishev, Dimitrina V. Guleva, Ljubka G. Miteva

“…For decades, IVIGs have been administered for treatment of infectious diseases and immune deficiencies, since they contain natural antibodies that represent a first-line defense against pathogens. Today their indication has expanded, including the off-label therapy for a variety of autoimmune and inflammatory diseases. …”
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The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke by Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha

“…Many studies highlighted that AGEs serum levels are correlated with the incidence, pathogenicity, and severity of AIS. However, the relationship between AGEs and AIS is not elucidated completely. …”
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Dendritic Cells and Their Multiple Roles during Malaria Infection by Kelly N. S. Amorim, Daniele C. G. Chagas, Fernando B. Sulczewski, Silvia B. Boscardin

“…In this way, DCs sense the presence of a myriad of pathogens, including Plasmodium spp., the causative agent of malaria. …”
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Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association by V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, T. L. Lapina, A. S. Trukhmanov, I. M. Kartavenko, V. A. Kiprianis, O. Z. Okhlobystina

“…It’s etiology includes genetic predisposition, bad habits, previous intestinal infections, psychosocial factors. The basic pathogenic factors may include HCl hypersecretion, stomach and duodenal dysmotility and visceral hypersensitivity. …”
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Vaccination ARN messager (ARNm), modèle de transition de la biologie fondamentale à la médecine by Sansonetti, Philippe J.

“…Years of “translational” research and development have culminated in the success of anti-Covid-19 mRNA vaccines and the promise of more to come against emerging pathogens. A new paradigm in vaccinology, enabling pandemics to be tackled as they emerge. …”
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Dual role of pyroptosis in liver diseases: mechanisms, implications, and therapeutic perspectives by Siyuan Yang, Yunyi Zou, Chunhua Zhong, Zuoqiong Zhou, Xiyang Peng, Changfa Tang

“…It facilitates the clearance of damaged hepatocytes, preventing secondary injury, and triggers immune responses to eliminate pathogens and damaged cells. Conversely, excessive pyroptosis intensifies inflammatory responses, exacerbates hepatocyte damage and promotes the activation and proliferation of hepatic stellate cells, accelerating liver fibrosis. …”
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Regulation of Dendritic Cell Function in Inflammation by André Said, Günther Weindl

“…During steady state immune surveillance in skin, DC act as sentinels against commensals and invading pathogens. Under pathological skin conditions, inflammatory cytokines, secreted by surrounding keratinocytes, dermal fibroblasts, and immune cells, influence the activation and maturation of different DC populations including Langerhans cells (LC) and dermal DC. …”
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Two Pediatric Cases of Primary Ciliary Dyskinesia Caused by Loss-of-Function Variants in Oral-Facial-Digital Syndrome Gene, OFD1 by Yifei Xu, Yuki Tsurinaga, Tsubasa Matsumoto, Ryuji Muta, Taichi Yano, Hiroshi Sakaida, Sawako Masuda, Koki Ueda, Guofei Feng, Shimpei Gotoh, Satoru Ogawa, Makoto Ikejiri, Kaname Nakatani, Mizuho Nagao, Masaki Tanabe, Kazuhiko Takeuchi

“…We report two male pediatric cases of PCD caused by hemizygous pathogenic variants in the OFD1 centriole and centriolar satellite protein (OFD1) gene. …”
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Generation and heterozygous repair of human iPSC lines from two individuals with the neurodevelopmental disorder, TRAPPC4 deficiency by Riley Hall, Tim Sikora, Annabelle Suter, Jia Yi Kuah, John Christodoulou, Nicole J Van Bergen

“…We have generated stem cells from fibroblasts of two individuals with the same homozygous TRAPPC4 c.454 + 3A > G pathogenic variant and used CRISPR/Cas9 editing to generate heterozygous gene-corrected isogenic controls. …”
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Prebiotic products based on kepok banana starch (Musa paradisiaca Formatypica) and moringa (Moringa oleifera) as functional food for female wistar rats by Luthfiyah Fifi, Ikayanti Retno, Dwipajati

“…Results showed significant differences in gut microbiota with MBS consumption, with higher concentrations of beneficial bacteria and reduced levels of pathogenic bacteria observed in the group receiving the highest MBS dose. …”
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Comprehensive Iranian guidelines for the diagnosis and management of maple syrup urine disease: an evidence- and consensus- based approach by Noushin Rostampour, Setila Dalili, Hossein Moravej, Zhila Afshar, Negar Yazdani, Seyedeh Tahereh Mousavi, Parastoo Rostami, Daniel Zamanfar, Maryam Yahay, Abdolhossein Nikravesh, Zahra Beyzaei, Mohamad Ahangar Davoodi, Atefeh Sedaghat, Tahora Hakemzadeh, Ali Talea

“…Abstract Maple Syrup Urine Disease (MSUD) disease is a defect in the function of the Branched-chain 2-ketoacid dehydrogenase complex (BCKDH). It is caused by pathogenic biallelic variants in BCKDHA, BCKA decarboxylase, or dihydrolipoamide dehydrogenase. …”
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Sous Vide Cookery: Foodservice Application for Larger, Less Tender Cuts by Chad Carr, Derek Griffing, Kaylie Madore, Dwain Johnson, Jason Scheffler, João Neto

“… Meat with an abundance of connective tissue presents a certain challenge to cooks who want to make it more tender while still properly eliminating pathogens that cause foodborne illness. Sous vide cookery provides precise temperature control and tenderness improvement with minimal supervision throughout cooking as well as consistent, almost perfect reproducibility. …”
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The Diversity of Airborne Bacteria Over the Tibet Plateau Decreased by Taklimakan Dust by Fanli Xue, Zhongwei Huang, Xuefei Huo, Qingqing Dong, Zhengpeng Li, Qianqing Gu

“…Moreover, the potential pathogens and bacterial ice nuclei (IN) in the Plateau increased by 16.4% and 73.8%, respectively. …”
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2019–2020 Florida Citrus Production Guide: Nematodes by Larry W. Duncan, Joe W. Noling, Renato N. Inserra

“… Integrated pest management (IPM) for nematodes requires (1) determining whether pathogenic nematodes are present within the grove; (2) determining whether population densities of some nematodes are high enough to cause economic loss; and (3) selecting a profitable management option. …”
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Synthesis and In Vitro Antimicrobial and Anthelminthic Evaluation of Naphtholic and Phenolic Azo Dyes by Joseph Kwasi Adu, Cedric Dzidzor Kodjo Amengor, Nurudeen Mohammed Ibrahim, Cynthia Amaning-Danquah, Charles Owusu Ansah, Dorcas Dzifa Gbadago, Joseph Sarpong-Agyapong

“…As part of the systematic investigation for biological activity, all the azo compounds exhibited good antimicrobial activity against the seven human pathogenic microorganisms. All the compounds exhibited anthelminthic activity against adult Ghanaian earthworms, Hyperiodrilus spp.…”
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Molecular mimicry in the pathogenesis of autoimmune rheumatic diseases by Michaela Fehringer, Thomas Vogl

“…Both commensal microbes in the human microbiome and pathogens can trigger molecular mimicry, thereby potentially contributing to the onset of ARDs.In this review, we focus on the role of molecular mimicry in the onset of rheumatoid arthritis and systemic lupus erythematosus. …”
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Genes Involved in the Biosynthesis and Transport of Acinetobactin in by Tarik Hasan, Chul Hee Choi, Man Hwan Oh

“…Pathogenic bacteria survive in iron-limited host environments by using several iron acquisition mechanisms. …”
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Role of probiotics to control gut-related diseases in animals by U. Laila, T. Varkey, M. Akram, M. Iftikhar, R. Zainab, T. Khalil, S. Adonis, G. Sołowski, F. Ahmet Ozdemir, M. Altable, C. Zeitler, Z. Merhavy

“…For the development of livestock breeding, different procedures are used, and the expectation of breeders is that probiotics show promising effects, including enhancing the growth rate of livestock, showing protective effects against various pathogens, and increasing production. Their application helps to achieve beneficial effects that are comparable to those of antibiotic-based growth stimulators banned on January 1st, 2006. …”
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The Occurrence and Diversity of Viruses Identified in Monocotyledonous Weeds by Evans Duah Agyemang, Rita Ofosu, Francesco Desiderio, Zsuzsanna Nagyne Galbacs, András Péter Takács, Éva Várallyay

“…In crop fields, weeds are perfect hosts for plant pathogenic viruses. The effects of these viruses can range from latent infection to plant death, affecting crop quality and yield and leading to economic loss in the world. …”
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Successful Diagnosis of Sengers Syndrome Using a Comprehensive Genomic Analysis by Kohta Nakamura, Yukiko Yatsuka, Sachie Naito, Akira Hasegawa, Takeya Kasukawa, Atsushi Kondo, Yoshihito Kishita, Yohei Sugiyama, Takanori Onuki, Tomohiro Ebihara, Tomoko Tsuruoka, Takuya Fushimi, Akira Ohtake, Kei Murayama, Atsuko Imai‐Okazaki, Yasushi Okazaki

“…Results Our analysis successfully diagnosed Sengers syndrome in a patient by detecting a known pathogenic variant and a previously unreported large deletion involving the AGK gene in a segmental duplication. …”
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