Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis by Aijaz Ahmad, Ravineel B. Singh, Kara L. Nickolich, Matthew J. Pilewski, Caden Ngeow, Kwame Frempong-Manso, Keven M. Robinson

“…Interleukin-17 (IL-17) and the Type 17 immune signaling pathway cytokine family are recognized for their pivotal role in fostering protective immunity against various pathogens. In this study, we investigate the role of IL-17 and Type 17 immune signaling components during IAPA.MethodsWild-type mice were challenged with influenza A H1N1 (flu) and then exposed to Aspergillus fumigatus ATCC42202 resting conidia on day 6 post-influenza infection, followed by the quantification of cytokines and chemokines at 48 h post-fungal infection.Results and discussionThe gene and protein expression levels revealed that IL-17 and Type 17 immune cytokines and antimicrobial peptides are downregulated during IAPA compared to mice singularly infected solely with A. fumigatus. …”
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Severe Necrotizing Adenovirus Tubulointerstitial Nephritis in a Kidney Transplant Recipient by Ravi Parasuraman, Ping L. Zhang, Dilip Samarapungavan, Leslie Rocher, Alan Koffron

“…Adenoviruses (AdV) are emerging pathogens with a prevalence of 11% viruria and 6.5% viremia in kidney transplant recipients. …”
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The Role of IL-33 in Gut Mucosal Inflammation by Luca Pastorelli, Carlo De Salvo, Maurizio Vecchi, Theresa T. Pizarro

“…Animal models of IBD were subsequently utilized in order to mechanistically determine the precise role of IL-33 in chronic intestinal inflammation, without, however, reaching conclusive evidence demonstrating whether IL-33 is pathogenic or protective. Indeed, data generated from these studies suggest that IL-33 may possess dichotomous functions, enhancing inflammatory responses on one hand and promoting epithelial integrity on the other. …”
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Association of PIK3CA somatic mutations with clinicopathological parameters in breast cancer by Gizem Teoman, Zeynep Turkmen Usta, Zeynep Sagnak Yilmaz, Sevdegul Aydin Mungan, Ismail Saygin

“…Of the 45 individuals with tumors carrying the PIK3CA mutation, 41 (91.2%) had only one mutation, while 4 (8.8%) had two. Pathogenic PIK3CA mutations were significantly correlated with tumor size ( p = 0.015) and tumor location ( p = 0.017). …”
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POTENTIAL RISKS ASSOCIATED WITH MISMANAGEMENT OF HOSPITAL WASTEWATER IN TANZANIA by Shadrack Mwita Sabai

“…The results show that effluents discharged into water bodies has high concentrations of organic matters and pathogenic bacteria (0.5 – 23 x 106 cfu/100 ml.). These results reveal that hospitals discharge is highly polluted and hence puts aquatic organisms and downstream water users into risks. …”
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Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient by Sudheer Nambiar, Asha Karippot, Joe Devasahayam, Tony Oliver

“…Tissue infections in cat bite wounds are commonly caused by pathogenic bacterium known as Pasteurella multocida. …”
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Test for Bacterial Content in Soy Sauce and Tomato Sauce at Masomba Market, Palu City by Hasrina

“…For further researchers, it is hoped that they will be able to examine other pathogenic bacteria and check the content of other food additives contained in soy sauce such as preservatives, thickeners.…”
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Defensive Mechanisms of <i>Mikania micrantha</i> Likely Enhance Its Invasiveness as One of the World’s Worst Alien Species by David R. Clements, Hisashi Kato-Noguchi

“…It possesses potent defenses against natural enemies such as pathogenic fungi, herbivorous insects, and parasitic nematodes, and exhibits allelopathic potential against plant competitors. …”
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Search for new antimicrobials against extended spectrum β-lactamase-positive Escherichia coli: Potential of fungi from the phylum Ascomycota by Walter Oliva Pinto Filho Segundo, Luciana Aires de Oliveira, Ana Cláudia Alves Cortez, Érica Simplício de Souza, Hagen Frickmann, João Vicente Braga de Souza

“…Abstract Pathogenic strains of Escherichia coli can cause gastrointestinal infections, urinary tract infections (UTIs), bacteremia, and other severe infections. …”
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PENANGANAN JERAWAT SINDROM AKUMULASI DAHAK MENGGUNAKAN AKUPUNTUR DAN HERBAL JIANGHUANG by Dyah Agesti, Suryani Dyah Astuti, Arifa Mustika

“…In Chinese Medicine, acne vulgaris belongs to categories of Feng Ci, it is caused by wind-heat pathogens that attack the lungs and excessive consumption of spicy and oily foods resulting in accumulation of heat in the stomach and intestines. …”
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Promoting Seed Germination of Some Plant Species by Rhamnolipid Produced by Pseudomonas aeruginosa by Zeena Ghazi Faisal

“…In wheat and barley seeds, applying rhamnolipid can protect seeds from pathogenic fungi while delaying their germination to 60% and 70% on the third day of sowing, while 90% and 100% have been reported in the control groups. …”
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Principles of portal hypertension treatment at patients with liver cirrhosis by Ye. A. Fedosina, M. V. Mayevskaya, V. T. Ivashkin

“…As the major part of these states peripheral vasodilation, prescription of vasoconstrictors (first of all — terlipressin) is pathogenically justified and results in arrest of acute bleedings from esophageal VV, and in functional recovery of kidneys at renal failure.…”
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Autoimmunity related to anti-Nax and anti-ZSCAN1 autoantibodies in adipsic hypernatremia by Akari Nakamura-Utsunomiya

“…In recent years, advances in clinical research have led researchers to recognize that an autoimmunological pathogenic mechanism might be associated with periventricular organs such as the subfornical organ (SFO). …”
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Stability, Bifurcation, and a Pair of Conserved Quantities in a Simple Epidemic System with Reinfection for the Spread of Diseases Caused by Coronaviruses by Jorge Fernando Camacho, Cruz Vargas-De-León

“…This model can be applied to study epidemics caused by SARS-CoV, MERS-CoV, and SARS-CoV-2 coronaviruses, since there is the possibility that, in diseases caused by these pathogens, individuals recovered from the infection have a decrease in their immunity and can be reinfected. …”
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Haemonchosis in Small Ruminants Under Traditional Husbandry Systems in Apac District, Northern Uganda by Charles Dickens Opeto, Harriet Angwech, Acaye Ongwech, Benard Abola, Steven Odongo, Geoffrey M. Malinga

“…Haemonchus contortus is one of the most common and fatal pathogenic gastrointestinal nematodes of small ruminants causing significant economic losses, particularly in low-income countries. …”
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The proclivity of free-ranging indigenous village chickens for night-time roosting in trees by Takele Taye Desta

“…It reduces contact with soiled bedding materials and droppings, parasites, and pathogens, consequently, it improves the health status and welfare of the family flock. …”
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Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024) by Pengpeng Ji, Meng Ma, Xiaoyue Geng, Jian Zhang

“…In 2024, WHO added multiple multidrug-resistant (MDR) Gram-negative bacteria to the bacteria priority pathogens list, and the continued increase in MDR Gram-negative bacteria poses a serious threat to public health. …”
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Autoimmune Hemolytic Anemia Associated with Mature Ovarian Cystic Teratoma Containing Monoclonal Immunoglobulin G: A Case Report and Review of Literature by Yuma Nato, Keiki Nagaharu, Keika Itoh, Naoki Shinke, Keiko Maeyama, Akihiko Sawaki, Hiroyuki Miyashita

“…Further research is necessary to elucidate the pathogenic relationship between such tumors and AIHA. …”
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Analysis of microorganisms and antibiotic resistance in medical instruments in the central sterile supply department (CSSD) of hospitals before and after sterilization by Hapsari Woro, Sajidan, Suranto, Hikmayani Nur Hafidha

“…Sterilization is essential in preventing the spread of pathogenic bacteria and antibiotic resistance in hospital settings. …”
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Management of a Difficult-to-Treat Diabetic Foot Wound Complicated by Osteomyelitis: A Case Study by Maram Alkhatieb, Hatan Mortada, Hattan Aljaaly

“…Predisposing factors in diabetic patients, known as the pathogenic triad, comprise trauma, ischemia, and neuropathy. …”
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