Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases by Themis Thoudam, Jae-Han Jeon, Chae-Myeong Ha, In-Kyu Lee

“…MAM provides an excellent platform for numerous signaling pathways; among them, inflammatory signaling pathways associated with MAM play a critical role in cellular defense during pathogenic infections and metabolic disorders. However, induction of MAM causes deleterious effects by amplifying mitochondrial reactive oxygen species generation through increased calcium transfer from the ER to mitochondria, thereby causing mitochondrial damage and release of mitochondrial components into the cytosol as damage-associated molecular patterns (DAMPs). …”
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A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

“…Crustin, a widely-studied antimicrobial peptides (AMPs), has been proven to be involved in mediating innate immune responses against intruding pathogens. In this study, a novel crustin-like gene, Cqcarc1, was characterized from the redclaw crayfish Cherax quadricarinatus. …”
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Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. …”
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BANNMDA: a computational model for predicting potential microbe–drug associations based on bilinear attention networks and nuclear norm minimization by Mingmin Liang, Xianzhi Liu, Juncai Li, Qijia Chen, Bin Zeng, Zhong Wang, Jing Li, Lei Wang

“…We conducted case studies on well-known drugs such as the Amoxicillin and Ceftazidime, as well as on pathogens such as Bacillus cereus and Influenza A virus, to further evaluate the efficacy of BANNMDA, and experimental outcomes showed that there were 9 out of the top 10 predicted drugs, along with 8 and 9 out of the top 10 predicted microbes having been corroborated by relevant literatures. …”
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Molecular Identification of Mycobacterium Species of Public Health and Veterinary Importance from Cattle in the South State of México by Adrian Zaragoza Bastida, Nallely Rivero Pérez, Benjamín Valladares Carranza, Keila Isaac-Olivé, Pablo Moreno Pérez, Horacio Sandoval Trujillo, Ninfa Ramírez Durán

“…Except M. parafortuitum, the other species identified are of public health and veterinary concern because they are pathogenic to humans, especially those with underlying medical conditions.…”
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Immunomodulatory Properties of HLA-G in Infectious Diseases by Laurence Amiot, Nicolas Vu, Michel Samson

“…In this review, we summarize the features of HLA-G expression by type of infections (i.e, bacterial, viral, or parasitic) detailing the state of knowledge for each pathogenic agent. The polymorphism, the interference of viral proteins with HLA-G intracellular trafficking, and various cytokines have been described to modulate HLA-G expression during infections. …”
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A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus by Nabia Shahreen, Jongsam Ahn, Adil Alsiyabi, Niaz Bahar Chowdhury, Dhananjay Shinde, Sujata S. Chaudhari, Kenneth W. Bayles, Vinai C. Thomas, Rajib Saha

“…Overall, our findings suggest that overflow metabolism offers S. aureus distinct bioenergetic advantages over a thermodynamically constrained TCA cycle, potentially supporting its commensal–pathogenic lifestyle.…”
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Diseases impact the performance of maize hybrids in southern Minas Gerais by Guilherme Vieira Pimentel, Luiz Daniel Rodrigues da Silva, Natalia Costa, Amanda Santana, Elisabete da Cruz Silva Watanabe, Silvino Guimarães Moreira

“…The evaluated traits were: severity (%) of foliar and ear diseases, incidence (%) of pathogens in grains, plant and ear height, yield, weight of 100 grains and final stand. …”
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Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy by Ting Gong, Boon Chin Heng, Edward Chin Man Lo, Chengfei Zhang

“…Apart from the potential health risks of immunological rejection and pathogenic transmission, the lack of a well-established banking system for the isolation and storage of dental-derived stem cells is the most pressing issue that awaits resolution and the properties of supportive scaffold materials vary across different studies and remain inconsistent. …”
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Transition Metal(II) Complexes with Cefotaxime-Derived Schiff Base: Synthesis, Characterization, and Antimicrobial Studies by Aurora Reiss, Mariana Carmen Chifiriuc, Emilia Amzoiu, Cezar Ionuţ Spînu

“…All the synthesized complexes were tested for in vitro antibacterial activity against some pathogenic bacterial strains, namely Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. …”
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C-Reactive Protein in Human Atherogenesis: Facts and Fiction by Oliver Zimmermann, Kefei Li, Myron Zaczkiewicz, Matthias Graf, Zhongmin Liu, Jan Torzewski

“…Whereas initial experimental studies suggested a pathogenic role for CRP in atherogenesis, more recent genetic data from Mendelian randomization trials failed to provide evidence for a causative role of CRP in cardiovascular disease. …”
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Detection of Staphylococcal Enterotoxins A and E and Methicillin Resistance in Staphylococcus aureus Strains From Moroccan Broiler Chicken Meat by Sabrine Nacer, Saâdia Nassik, Fatima Zahra El Ftouhy, Sophia Derqaoui, Mohamed Mouahid, Mustapha Lkhider

“…Foods of animal origin, in particular chicken meat, are considered to be potential vectors of pathogenic bacteria, particularly Staphylococcus aureus. …”
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Young Woman with Unexplained Neutropenia and Neutrophils with Bilobed Nuclei: Marrow Findings by Martin Barnes, Victoria Shklar, Dipen Patel, Harry Staszewski

“…Germline testing in the LBR gene revealed a heterozygous pathogenic mutation, namely, the PR57837.17 variant, confirming the diagnosis of hereditary disease. …”
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Biological Synthesis of Silver Nanoparticles by Cell-Free Extract of Spirulina platensis by Gaurav Sharma, Nakuleshwar Dut Jasuja, Manoj Kumar, Mohammad Irfan Ali

“…Furthermore, the synthesised nanoparticles exhibited high antibacterial activity against pathogenic Gram-negative, that is, Escherichia coli, MTCC-9721; Proteus vulgaris, MTCC-7299; Klebsiella pneumoniae, MTCC-9751, and Gram-positive, that is, Staphylococcus aureus, MTCC-9542; S. epidermidis, MTCC-2639; Bacillus cereus, MTCC-9017, bacteria. …”
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Novel IL2RG gene mutation causing primary combined immunodeficiency disease: A case report and literature review by Fang Cao, Yingyu Shi, Fang Deng, Yu Yan

“…Whole exome sequencing did not identify any genetic variants highly associated with and definitively pathogenic for bronchiectasis but detected a compound heterozygous missense mutation c.420A>T (p.R140S) in the IL2RG gene, linked to primary combined immunodeficiency (CID), a clinical phenotype rarely reported in China due to this gene mutation. …”
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Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms by Daniel Ménard

“…These new cells lines could serve important applications in the study of pathogenic action and epithelial regeneration.…”
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Dysfunction of G Protein-Coupled Receptor Kinases in Alzheimer's Disease by William Z. Suo, Longxuan Li

“…Although mutations and variations of several genes have been identified to be involved in Alzheimer's disease (AD), the efforts towards understanding the pathogenic mechanisms of the disease still have a long journey to go. …”
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Multiple Adenomatous Duodenal Polyposis by Zdena Zádorová, Jan Hajer, Václav Mandys

“…Afterwards we screened the patient for germline MYH mutations using the denaturing high-performance liquid chromatography (DHPLC) in combination with sequencing. No novel pathogenic mutation has been identified. Large polyps were removed by means of endoscopic polypectomy and mucosectomy, while small polyps were removed by means of argon plasma coagulation.We conduct yearly checkups, removing only sporadic polyps. …”
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Epidemiology of subclinical mastitis in family size dairy farms in hatay region by Yaşar Ergün, Özkan Aslantaş, Zafer Cantekin

“…A total of 262 milk samples from 115 (71.9 %) mastitic cows were investigated for aerobic pathogenic microorganism. From this 262 milk samples, 231 aerobic microorganisms were isolated and identified in 200 milk samples. …”
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Comparison of the antibacterial efficacy of 810 nm diode laser and photodynamic therapy in reducing microbial flora in patients with peri-implant mucositis – An in vivo study by Poonam Siwach, Reshu Sanan, Abhishek Nagpal, Omkar Krishna Shetty, Amit Bhardwaj, Mukesh Sharma

“…Conclusion: Within the limitations of the study, it can be concluded that there is a definitive reduction in pathogenic bacteria with both interventions and PDT offers clinically visible benefits in the treatment of peri-implant mucositis.…”
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