Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

“…Recessive dystrophic epidermolysis bullosa (RDEB) is a severe blistering disease caused by COL7A1 pathogenic variants. Although underscored by animal studies, the endotypes of human RDEB are poorly understood. …”
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Multiorgan Failure and Refractory Lactic Acidosis due to Pasteurella multocida Septicemia in a Patient with No Animal Exposure by Damaris Pena, Yaneidy Santana, Jose Perez Lara, Efrain Gonzalez, Misbahuddin Khaja

“…Pasteurella multocida is a gram-negative coccobacillus pathogenic to animals. It can cause infection in humans by a bite, scratch, or lick from a cat or dog. …”
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Monkeypox: a re-emergent virus with global health implications – a comprehensive review by Nourhan G. Naga, Enas A. Nawar, A’laa A. Mobarak, Aya G. Faramawy, Hend M. H. Al-Kordy

“…The epidemic is divided into two clades: Clade I and Clade II, which have distinct pathogenic characteristics. Diagnostic approaches have developed with advances in molecular techniques, yet problems persist in resource-constrained situations. …”
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COVID-19 vaccination: challenges in the pediatric population by Alice Nicoleta Azoicai, Ingrith Miron, Ancuta Lupu, Monica Mihaela Alexoae, Iuliana Magdalena Starcea, Mirabela Alecsa, Vasile Valeriu Lupu, Ciprian Danielescu, Alin Horatiu Nedelcu, Delia Lidia Salaru, Felicia Dragan, Ileana Ioniuc

“…Vaccination is considered to be one of the most effective means of protecting individuals and populations from the risks associated with exposure to various pathogens. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affected people of all ages worldwide. …”
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Large Right Atrial Thrombus Associated with Central Venous Catheter Requiring Open Heart Surgery by Nasir Hussain, Paul Eric Shattuck, Mourad Hussein Senussi, Erwin Velasquez Kho, Mubeenkhan Mohammedabdul, Devang K. Sanghavi, Usman Mustafa, Arvind Balavenkataraman, Dragic M. Obradovic

“…Incidences of CVC-related right atrial thrombosis (CRAT) are variable, but, when right atrial thrombus is present, it carries a mortality risk of 18% in hemodialysis patients and greater than 40% risk in nonhemodialysis patients. Different pathogenic mechanisms have been postulated for the development of CRAT, which includes mechanical irritation of the myocardial wall, propagation of intraluminal clot, hypercoagulability, and hemodynamics of right atria. …”
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The Effects of Microplastic Pollution on Marine Organisms and its Impact on Human Health: A Review by Aran Akbari, Jalil Jaafari

“…MPs in marine environments provide a highly selective and flexible support platform for a variety of microbial communities, especially resistant pathogens. The accumulation of MPs in marine organisms consumed as human food has dangerous consequences for human health, leading to physical and chemical toxic effects. …”
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Mixed Ligand Complexes of N-Methyl-N-phenyl Dithiocarbamate: Synthesis, Characterisation, Antifungal Activity, and Solvent Extraction Studies of the Ligand by Anthony C. Ekennia, Damian C. Onwudiwe, Cyril Ume, Eno E. Ebenso

“…The compounds were screened for three human pathogenic fungi: Aspergillus flavus, Aspergillus niger, and Candida albicans. …”
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Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins by Sajad Chamani, Vanessa Bianconi, Aida Tasbandi, Matteo Pirro, George E. Barreto, Tannaz Jamialahmadi, Amirhossein Sahebkar

“…In recent years, compelling evidence has shown that impairment of resolution of inflammation is a crucial pathogenic hallmark in different neurodegenerative disorders, including Alzheimer’s disease and Parkinson’s disease. …”
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Chronic Lymphocytic Leukemia and Myelofibrosis by Fares Darawshy, Arieh Ben-Yehuda, Karine Atlan, Deborah Rund

“…This case reported here constitutes an unusual situation of CLL characterized by the development of PMF. Etiologic and pathogenic associations—the role of t (1; 6) and JAK-2 V617F mutation—are discussed.…”
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Transcriptional regulation of suberin and its response to the environment by ZHOU Yue, AN Yongping, MA Rong, WANG Pei

“…Acting as a barrier between the plants and their environment, suberin controls the transport of water and solutes, protecting plants from environmental stresses and pathogenic invasion. This article reviews the key enzymes and transcription factors involved in suberin biosynthesis, and discusses the impact of environmental factors on suberin synthesis and deposition. …”
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Selected fermented indigenous vegetables and fruits from Malaysia as potential sources of natural probiotics for improving gut health by Olaide Olawunmi Ajibola, Raymond Thomas, Babatunde Femi Bakare

“…Food preservation and processing play a vital role in the inhibition of food pathogens in fruits and vegetables that are prevalent in Malaysia. …”
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Evaluation of Antimicrobial Activity Using Cadmium Oxide Nanoparticles Prepared by Physical Method (PLAL) by Nisreen Kh. Abdalameer, Tuqa A. Khaleefa

“…The findings of the study indicate that CdO NPs synthesized using the PLAL technique possess antibacterial properties, rendering them effective in eradicating pathogenic bacteria and fungi. …”
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Epidemic spread of influenza viruses: The impact of transient populations on disease dynamics by Karen R. Ríos-Soto, Baojun Song, Carlos Castillo-Chavez

“…The recent H1N1 ('swine flu') pandemic and recent H5N1 ('avian flu') outbreaks have brought increased attention to the study of the role of animal populations as reservoirs for pathogens that could invade human populations. It is believed that pigs acquired flu strains from birds and humans, acting as a mixing vessel in generating new influenza viruses. …”
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Investigation of new exopolysaccharides produced by strains of donkey milk by Arevik Israyelyan, Tsovinar Balabekyan, Lara Aleksanyan, Inesa Sahakyan, Anna Gasparyan, Flora Тkhruni

“…Results: The antimicrobial activity of the polysaccharide and antimicrobial protein-like fractions of the genus Enterococcus strains depends on its concentration, time of interaction with the test culture, and the species of the pathogenic bacteria. Conclusion: The obtained results were shown that strains isolated from fermented donkey milk that are capable of synthesizing two substances of different nature with high antimicrobial properties during the growth process are promising for further research and application for their use as probiotics and biopreparations in pharmaceuticals. …”
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Genetic Diversity and Population Differentiation of the Causal Agent of Citrus Black Spot in Brazil by Ester Wickert, Antonio de Goes, Andressa de Souza, Eliana Gertrudes de Macedo Lemos

“…The same haplotypes were sampled in different populations from the same and different orange varieties and from similar and different origins. If new and pathogenic fungi would become resistant to fungicides, the observed genetic structure could rapidly spread this new form from one population to others.…”
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All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study by Deng Li, Peng Wang, Yuxi Li, Zhongyu Xie, Le Wang, Hongjun Su, Wen Deng, Yanfeng Wu, Huiyong Shen

“…ATRA-pretreated MSCs significantly decreased not only the vital pathogenic cytokine in AS, tumor necrosis factor-α (TNF-α), but also AS-boosting factors interleukin-17 (IL-17A) and interferon-γ (IFN-γ). …”
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Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases by Néstor DelaPaz-Ruíz, Ellen-Wien Augustijn, Mahdi Farnaghi, Sheheen A. Abdulkareem, Raul Zurita Milla

“…To that end, we developed an integrated Agent-Based Model (ABM) that facilitates analysis in space and time at various temporal resolutions, including disease spread, population mobility and wastewater production, while also being sufficiently generic for different types of infectious diseases or pathogens. The integrated model replicates the epidemic curve for COVID-19 and can estimate the daily infections at the household level, enabling the monitoring of the spatial patterns of infection intensity. …”
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A hydrogel based herbal nanoformulation for enhanced wound healing by Shaheen Sultana, Nada Alzahrani, Reem Alzahrani, Wejdan Alshamrani, Waad Aloufi, Maria Khan, Mohammad Yusuf

“…Nanoformulation based hydrogel showed significantly enhanced antimicrobial activity against tested pathogenic microbial strains in comparison to drug solution, as well as marketed formulations.…”
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A Case of Influenza B and Mycoplasma pneumoniae Coinfection in an Adult by Taro Shinozaki, Kotaro Sasahara, Eri Iwami, Aoi Kuroda, Tatsu Matsuzaki, Takahiro Nakajima, Takeshi Terashima

“…M. pneumoniae should be considered as one of the causative pathogens in influenza coinfection cases with CT scan images presenting dense consolidation.…”
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Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development by Aiswarya M. Rajesh, Shraddha Subhash Pawar, Kruthi Doriya, Rambabu Dandela

“…Key antibiotics discussed include carvacrol, dalbavancin, quinolones, fluoroquinolones, and zoliflodacin, each with unique actions against bacterial pathogens. Bacteria have evolved complex resistance strategies, such as enzyme production to neutralize drugs, modifying drug targets, and using efflux pumps to remove antibiotics, significantly reducing drug efficacy. …”
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