Role of Mast Cells and Type 2 Innate Lymphoid (ILC2) Cells in Lung Transplantation by Esmaeil Mortaz, Saeede Amani, Sharon Mumby, Ian M. Adcock, Mehrnaz Movassaghi, Jelle Folkerts, Johan Garssen, Gert Folkerts

“…These cells, therefore, will encounter external stimuli and pathogens. MCs modulate both the innate and the adaptive immune response in inflammatory disorders including transplantation. …”
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Bilateral Ampiginous Choroiditis following Presumed SARS-CoV-2 Infection by Elysse S. Tom, K. Matthew McKay, Steven S. Saraf

“…Ampiginous choroiditis is an inflammatory chorioretinopathy with an unknown pathogenic mechanism that often necessitates early immunomodulatory therapy. …”
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The large-scale whole-genome sequencing era expedited medical discovery and clinical translation by Qingxin Yang, Shuhan Duan, Yuguo Huang, Chao Liu, Mengge Wang, Guanglin He

“…This imbalance has hampered health equity and precision medicine, resulting in limited transferability of polygenic risk scores to underrepresented populations and misinterpretations of the pathogenicity of genomic variants. Recent advancements in sequencing technology have enabled the implementation of large-scale, high-quality, diverse, multi-omics, and engineered genomic projects, including the All of Us Research Program and the Trans-Omics for Precision Medicine Program. …”
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Identification of bapA in Strains of Salmonella enterica subsp. enterica Isolated from Wild Animals Kept in Captivity in Sinaloa, Mexico by Gabriela Silva-Hidalgo, Martin López-Valenzuela, Nora Cárcamo-Aréchiga, Silvia Cota-Guajardo, Mayra López-Salazar, Edith Montiel-Vázquez

“…Biofilm formation is associated with the ability to persist in different environments, which contributes to the pathogenicity of several species. We analyzed the presence of bapA in 83 strains belonging to 17 serovars of Salmonella enterica subsp. enterica from wildlife in captivity at Culiacan’s Zoo and Mazatlán’s Aquarium. …”
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Differential Stress Responses to Rice Blast Fungal Infection Associated with the Vegetative Growth Phase in Rice by Takuma Koyama, Takumi Tezuka, Atsushi J. Nagano, Jiro Murakami, Takanori Yoshikawa

“…While much knowledge has been obtained about changes in disease resistance as growth stages progress, knowledge about changes in plant responses to pathogens with progressing age in plants is limited. …”
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Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us? by Iván Sanz-Muñoz, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Corina S. Concha-Santos, Marta Hernández, Silvia Rojo-Rello, Marta Domínguez-Gil, Ahmed Mostafa, Luis Martinez-Sobrido, Jose M. Eiros, Aitor Nogales

“…ABSTRACT The current situation with H5N1 highly pathogenic avian influenza virus (HPAI) is causing a worldwide concern due to multiple outbreaks in wild birds, poultry, and mammals. …”
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Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming by Maciej Nowak, Zbigniew Paluszak, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska-Buda, Anna Budzyńska, Joanna Skonieczna-Kurpiel, Ewa Wałecka-Zacharska, Monika Huse-Kutowska, Krzysztof Skowron

“…The use of natural fertilizers during organic farming can be a source of pathogens, including L. monocytogenes in the soil and finally in vegetables and fruits. …”
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Hypoxemic Respiratory Failure from Acute Respiratory Distress Syndrome Secondary to Leptospirosis by Shannon M. Fernando, Pierre Cardinal, Peter G. Brindley

“…The most common precipitant is community-acquired bacterial pneumonia, but other putative pathogens include viruses and fungi. On rare occasions, ARDS can be secondary to tropical disease. …”
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cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

“…The cGAS/STING signaling pathway, a pivotal mechanism in innate immunity, detects cytosolic DNA from pathogens or cellular damage, triggering immune responses via type I interferons and inflammatory cytokines. …”
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mGBP2 engages Galectin-9 for immunity against Toxoplasma gondii. by Elisabeth Kravets, Gereon Poschmann, Sebastian Hänsch, Veronica Raba, Stefanie Weidtkamp-Peters, Daniel Degrandi, Kai Stühler, Klaus Pfeffer

“…Murine GBPs (mGBPs) recognize T. gondii PVs and assemble into supramolecular mGBP homo- and heterocomplexes that are required for the disruption of the membrane of PVs eventually resulting in the cell-autonomous immune control of vacuole-resident pathogens. We have previously shown that mGBP2 plays an important role in T. gondii immune control. …”
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Prevalence of Brucellosis among Women Presenting with Abortion/Stillbirth in Huye, Rwanda by Nadine Rujeni, Léonidas Mbanzamihigo

“…More mechanistic studies will also demonstrate the pathogenicity of Brucella in human placentas.…”
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A review on the microbiology of Ethiopian traditional fermented beverage products by Guesh Mulaw, Trhas Gebregziabher, Teklemichael Tesfay

“…It also helps to reduce the amount of toxins and pathogens in food. Similarly, fermented foods contain probiotics, which are beneficial bacteria that help the body to digest food and absorb nutrients. …”
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The growing challenge of autism spectrum disorder: a comprehensive review of etiology, diagnosis, and therapy in children by Chunyuan Wang, Hong Wang

“…Finally, this paper summarizes the current status of autism research, looks forward to future research directions, and calls for more research to explore the pathogenic mechanisms, diagnostic basis, and therapeutic methods of autism.…”
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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

“…Iron plays a key role in many of the key pathogenic steps concurring in the development and progression of MFLS, notably including genetics, intestinal dysbiosis, adipositis, insulin resistance, metaflammation, oxidative stress and ferroptosis, endoplasmic reticulum stress, and hepatic fibrosis. …”
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Preparation of Copper Nanoparticles/Diatomite Nanocomposite for Improvement in Water Quality of Fishponds by Truong Thi Hanh, Nguyen Thuy Lan Chi, Nguyen Ngoc Duy

“…Antibacterial activity of CuNPs/DA nanocomposite against pathogenous bacteria for catfish such as Aeromonas hydrophila and Edwardsiella ictaluri was estimated.…”
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Necrotizing Epididymo-Orchitis: A Rare Manifestation of COVID-19 by Ali Tavoosian, Sana Ahmadi, Seyed Mohammad Kazem Aghamir

“…It is caused by sexually transmitted microorganisms and nonsexual transmitted pathogens. Viruses such as mumps and cytomegalovirus can also cause epididymo-orchitis. …”
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Electroacupuncture Stimulation Suppresses Postoperative Inflammatory Response and Hippocampal Neuronal Injury by Xiang-feng Wang, Qin Lin, Guan-hui Wang, Gen-ming Zhan, Wei Liu, Zhi-wei Lin

“…These findings indicated the POCD was the synergistic outcome of anaesthesia and surgical stimulation but with different pathogenic mechanism. The surgery with mental tri-needles (surgery+MTN) group outperformed the surgery group in terms of cognitive function performance. …”
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Microevolution during Chronic Infection May Lead T. asahii to Coexist with the Host by Gen Ba, Xuelian Lv, Xin Yang, Wenling Wang, Junhong Ao, Rongya Yang

“…Compared with the primary T. asahii strain, the microevolved strain induced much lower expression of TNF-α by mice bone marrow-derived DC and had a much superior survival rate, a total of 2212 significantly differentially expressed genes were identified in the microevolved strain, and functional analysis showed significance in the downregulated transcription and metabolic process, especially the valine, leucine, and isoleucine degradation pathways, which were associated with pathogenicity and virulence; hence, the results were highly consistent with the decreased immunogenicity and virulence of the microevolved strain. …”
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Cyst Nematode (Heterodera glycines) Problems in Soybean (Glycine max L.) Crops and Its Management by Gebissa Yigezu Wendimu

“…Hence, the reason behind the writing of this chapter is to explore the different published scientific papers related to soybean cyst nematode’s economic importance, distribution, symptoms, biology, life cycle, interaction with other pathogens, different management approaches, and its prospects. …”
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Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue by Sofia Dias, Sílvia Paredes, Laura Ribeiro

“…Obesity and dyslipidemia are main features of metabolic syndrome, and both can present with adipose tissue dysfunction, involved in the pathogenic mechanisms underlying this syndrome. We revised the effects, and underlying mechanisms, of the current approved drugs for dyslipidemia and obesity (fibrates, statins, niacin, resins, ezetimibe, and orlistat; sibutramine; and diethylpropion, phentermine/topiramate, bupropion and naltrexone, and liraglutide) on adipose tissue. …”
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