Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction by Yue Peng, Junze Wu, Yi Sun, Yuanxing Zhang, Qiyao Wang, Shuai Shao

“…Abstract Identifying and characterizing virulence proteins secreted by Gram-negative bacteria are fundamental for deciphering microbial pathogenicity as well as aiding the development of therapeutic strategies. …”
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Characterization of patients with cerebrovascular diseases in the acute stage according to traditional Chinese diagnosis by Omar Morejón Barroso, Zaida Pérez Meneses, Ernesto Julio Bernal Valladares, Leticia Varela Castro

“…Subarachnoid hemorrhage: 15% as severe flaccid type attack; and 17.6% liver Yin deficiency syndrome. The most frequent pathogenic factor was internal wind, present in 90.0% of cases.…”
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Superbugs-related prolonged admissions in three tertiary hospitals, Kano State, Nigeria by Alkali, Bashir, Garba, Iliyasu, Adamu, Almustapha Aliero, Abdurrazak, Kibiya, Muhammad, Hassan Abubakar, Ibrahim, Ntulume, Faruku, Sarkinfada, Ezera, Agwu

“…Introduction: Superbugs are pathogenic microorganism and especially a bacterium that has developed resistance to the medications normally used against it. …”
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Clinical characteristics and risk factors of severe pneumonia caused by human bocavirus in children by Zhuxia Li, Wenjing Gu, Fengming Zhu, Enze Han, Yongdong Yan, Huiquan Sun, Weidong Xu, Xin Zhang, Li Huang, Shan Gao, Yuqing Wang, Chuangli Hao, Xinxing Zhang

“…There were no significant differences in age distribution, presence of fever, lung moist rales, pleural effusion and reduced breath sounds between the two groups (all P > 0.05). 57.19% of the HBoV-positive children co-infected with other pathogens and HRV was the most common co-infected pathogens with HBoV. …”
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Immune response and growth performance of crayfish Cherax quadricarinatus fed with supplementary diet of synbiotic by Amrullah Amrullah, Wahidah Wahidah

“…Furthermore, the challenge test was performed against the pathogenic bacteria of A. hydrophila and reared for a week. …”
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Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning by D. E. Ivanoshchuk, A. B. Kolker, O. V. Timoshchenko, S. E. Semaev, E. V. Shakhtshneider

“…A negative result of genetic screening for pathogenic variants in genes of the low-density lipoprotein receptor and its ligands does not rule out a diagnosis of familial hypercholesterolemia. …”
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The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov

“…Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. …”
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Biopreservation of Shrimps Using Composed Edible Coatings from Chitosan Nanoparticles and Cloves Extract by Ahmed A. Tayel, Aml F. Elzahy, Shaaban H. Moussa, Mohammed S. Al-Saggaf, Amany M. Diab

“…The entire agents (Cht-NPs, CLE, and CLE/Cht-NPs) exhibited remarkable antibacterial activities toward all food-borne pathogens; CLE/Cht-NPs were significantly the most forceful. …”
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Dietary Fe-Gly supplementation attenuates enterotoxigenic Escherichia coli (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets by Qing Gao, Qing Gao, Qing Gao, Yilong Zhang, Yabin Wu, Dianchao Gu, Junzhou Chen, Conghui Yin, Hao Wu, Dan Zhu, Daiwen Chen, Aimin Wu

“…This decreases the iron available for pathogenic microorganisms in the gut, thereby inhibiting the proliferation of intestinal pathogens and ensuring the intestinal health of piglets.…”
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A collaborative network analysis for the interpretation of transcriptomics data in Huntington’s disease by Ozan Ozisik, Nazli Sila Kara, Tooba Abbassi-Daloii, Morgane Térézol, Elsa C. Kuijper, Núria Queralt-Rosinach, Annika Jacobsen, Osman Ugur Sezerman, Marco Roos, Chris T. Evelo, Anaïs Baudot, Friederike Ehrhart, Eleni Mina

“…Taking this one step further, we hypothesized that combining and analyzing the results from multiple network-based methods could provide data-driven hypotheses of pathogenic mechanisms from multiple perspectives. We analyzed a Huntington’s disease transcriptomics dataset using six network-based methods in a collaborative way. …”
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Pandemic one health clones of Escherichia coli and Klebsiella pneumoniae producing CTX-M-14, CTX-M-27, CTX-M-55 and CTX-M-65 ESβLs among companion animals in northern Ecuador by Fernando A. Gonzales-Zubiate, José Humberto M. Tambor, José Humberto M. Tambor, Juan Valencia-Bacca, María Fernanda Villota-Burbano, Adriana Cardenas-Arias, Adriana Cardenas-Arias, Fernanda Esposito, Fernanda Esposito, Quézia Moura, Bruna Fuga, Bruna Fuga, Bruna Fuga, Elder Sano, Jesus G. M. Pariona, Mishell Poleth Ortiz Jacome, Nilton Lincopan, Nilton Lincopan, Nilton Lincopan

“…From a One Health perspective, dogs and cats have begun to be recognized as important reservoirs for clinically significant multidrug-resistant bacterial pathogens. In this study, we investigated the occurrence and genomic features of ESβL producing Enterobacterales isolated from dogs, in the province of Imbabura, Ecuador. …”
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Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

“…Complementary analyses showed that these variants are predicted pathogenic and the missense variant Leu230Arg significantly affects the stability and structure modelling of the ABHD14A protein. …”
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Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing by Colin T. Konishi, Nancy Mulaiese, Tanvi Butola, Qinkun Zhang, Dana Kagan, Qiaoyan Yang, Mariel Pressler, Brooke G. Dirvin, Orrin Devinsky, Jayeeta Basu, Chengzu Long

“…Here, we utilized a personalized adenine base editor (ABE)-mediated approach to correct the pathogenic variant efficiently and precisely to restore neuronal dendritic morphology. …”
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Evaluation of chitinase production ability to antagonize Pyricularia Oryzae of bacteria and actinomycete strains isolated from rice root soil in Kien Giang Province by Đinh Anh Hòa, Trần Thị Phấn, Trần Thùy Trang, Nguyễn Thị Ánh Nguyệt, Nguyễn Thị Thùy Dương, Nguyễn Hải An, Lê Thị Mai Châm

“…Therefore, biological products containing microorganisms that can antagonize fungal pathogens and are environmentally friendly, are promising measure to control this disease. …”
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Liquid smoke-infused edible coatings: Antimicrobial agents for preserving cherry tomatoes by Muhammad Faisal, Dieni Mansur, Hera Desvita, M. Bagas Heriansyah

“…The effectiveness of edible coating was tested based on antibacterial activity against 4 types of pathogenic bacteria, namely Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis, as well as 2 fungi including Candida albicans and Aspergillus niger. …”
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Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases by Mohamed Elbadawy, Nagisa Saito, Yuki Kato, Kimika Hayashi, Amira Abugomaa, Mio Kobayashi, Toshinori Yoshida, Makoto Shibutani, Masahiro Kaneda, Hideyuki Yamawaki, Kazuaki Sasaki, Tatsuya Usui, Tsutomu Omatsu

“…Abstract Bat is considered a natural reservoir of various important pathogens, including severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2, Ebola virus, and Nipah virus. …”
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Genomic characterization and evolutionary analysis of a Getah virus variant from piglets in central China by Zhenhua Guo, Yao Jiang, Peng Li, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang

“…The genomic characteristics and evolutionary relationship of the pathogenic viral strain were also analyzed.ResultsThe isolate GETV-HeN202309 shared the highest nucleotide identity of 99.8% with strains from Guangdong and Sichuan province, suggesting it is an imported transmission. …”
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The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin by Jin Zeng, Fuyang Song, Yi Yang, Chenjie Ma, Guangcun Deng, Yong Li, Yujiong Wang, Xiaoming Liu

“…However, studies of its pathogenic roles and functional mechanisms have been hampered due to the difficulty of purification and lack of specific antibodies against this toxin. …”
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High-Throughput 16 S rRNA Gene Sequencing Reveals Bacterial Diversity of Infant Formula Production Line Samples in Spring and Summer by Xian Li, Yongbo Li, Yalun Zhang, Rui Zhang, Hui Wang, Tao Zhang, Taotao Yan, Zilun Zhang, Guohua Shi, Wei Zhou

“…The potential bacterial pathogens were identified as Pseudomonas aeruginosa in spring and Acinetobacter baumannii in summer. …”
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Development and Application of <i>Lactobacillus plantarum</i> PSCPL13 Probiotics in Olive Flounder (<i>Paralichthys olivaceus</i>) Farming by Muhammad Aleem Abbas, Hae-Jung Kim, Ga-Yeong Lee, Hae-Yeon Cho, Syed Al Jawad Sayem, Eon-Bee Lee, Seung-Jin Lee, Seung-Chun Park

“…After screening 16 <i>Lactobacillus</i> isolates, PSCPL13 was selected because of its potential broad-spectrum antibacterial activity against many pathogens, such as <i>Vibrio</i> and <i>Edwardsiella</i>. …”
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