Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study by Nawal M. Alanazi, Nasser H. Alshanbari, Hala M. Roushdy, Yahya I. Alnshbah, Eman Ali Barnawi, Nawaf M. Almatrafi, Rula Felemban, Zainah M. Al Shahrani, Nadeen Burhan, Aiman El-Saed, Khalid H. Alanazi

“…The high resistance of causative pathogens and high associated mortality underscore the importance of strict implementation of infection control measures.…”
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Septoriablotch epidemic process on spring wheat varieties by E. Yu. Toropova, O. A. Kazakova, V. V. Piskarev

“…In the control systems of Septoriablotch the main ecologically safe element is resistant  varieties, which are designed to slow down the pathogens reproduction rate and slow down or stop the development of the epiphytotic process. …”
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In ovo delivery of carvacrol triggers expression of chemotactic factors, antimicrobial peptides and pro-inflammatory pathways in the yolk sac of broiler chicken embryos by Mila M. Y. Meijer, Henry van den Brand, Shahram Niknafs, Eugeni Roura

“…Conclusion In conclusion, these findings suggest that in ovo delivery of carvacrol has the potential to enhance anti-pathogenic and pro-inflammatory responses in the yolk sac via upregulation of antimicrobial peptides, and NOD-like receptor pathways.…”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…Both XBB and BA.2.86 variants exhibit lower pathogenicity. This study provides vital scientific evidence on the epidemiological features, clinical manifestations, and control strategies of SARS-CoV-2 variants. …”
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Results of Selective Biochemical Screening for Lysosomal Acid Lipase Deficiency and Sequencing of the <i>LIPA</i> Gene in the Risk Group Patients by S. V. Shtykalova, A. A. Egorova, O. S. Glotov, A. V. Kiselev, I. Yu. Kogan

“…For 17 patients, search for mutations in the LIPA gene was carried out using NGS. In 9 patients, pathogenic genetic variants were found that led to decrease in LAL activity and the manifestation of clinical symptoms. …”
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Genotype-phenotype correlations for 17 Chinese families with inherited retinal dystrophies due to homozygous variants by Xue Fan, Zhen Li, Lingzhi Sha, Xunlun Sheng, Weining Rong

“…The results of the study indicate that more than 80% of persons with homozygous variant originated from non-consanguineous families, emphasizing the significance of genetic screening for individuals who lack a family history of consanguineous marriage and no obvious clinical phenotypes, but who may carry genetic pathogenic variants for genetic diseases. Furthermore, by analyzing the genotypes and clinical phenotypes of IRD patients from these 17 Chinese families, we have expanded the spectrum of variants in known pathogenic genes for IRDs and the range of clinical phenotypes associated with variants in these genes. …”
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Global prevalence of platelet-type von Willebrand disease by Omid Seidizadeh, Andrea Cairo, Maha Othman, Flora Peyvandi

“…Considering these 4 known pathogenic variants, we estimated a global PT-VWD prevalence of 136 cases/106. …”
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Glutamine-glutamate centered metabolism as the potential therapeutic target against Japanese encephalitis virus-induced encephalitis by Mengyuan Li, Hang Yuan, Xiaofei Yang, Yingfeng Lei, Jianqi Lian

“…Therefore, uncovering and manipulating the metabolic reprogramming that underlies viral infection will help elucidate the pathogenic mechanisms and develop novel therapeutic strategies. …”
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Detection and Phylogenetic Characterization of Influenza D in Swedish Cattle by Ignacio Alvarez, Fereshteh Banihashem, Annie Persson, Emma Hurri, Hyeyoung Kim, Mariette Ducatez, Erika Geijer, Jean-Francois Valarcher, Sara Hägglund, Siamak Zohari

“…The samples were screened for IDV and other respiratory pathogens using real-time reverse transcription quantitative PCR (rRT-qPCR). …”
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Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis by Xiaoyu Huang, Zhouao Zhang, Zhouyi Wang, Tiancheng Luo, Mingjin Yang, Xinyan Guo, Xue Du, Tianyu Ma, Yong Zhang

“…Intraperitoneal injection of B022 ameliorated the severity of EAMG rats, and reduced proportion of pathogenic B and T cell subsets, antibody levels and postsynaptic membrane damage. …”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

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Chemokines and Chemokine Receptors in Multiple Sclerosis by Wenjing Cheng, Guangjie Chen

“…Chemokines, which are small peptide mediators, can attract pathogenic cells to the sites of inflammation. Each helper T cell subset expresses different chemokine receptors so as to exert their different functions in the pathogenesis of MS. …”
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Anthropisation et maladies à tique : l’exemple de la borréliose de Lyme by Boulanger, Nathalie

“…As it is likely to transmit other microorganisms potentially pathogenic to humans, an integrated multidisciplinary approach to identify human practices promoting its expansion is critical to control the (re)emergence of infectious diseases. …”
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Generation of human induced pluripotent stem cell lines from three different male XLRS patients carrying RS1 gene mutation by Sang-Yun Kim, Yong-Min Choi, Yunho Park, Seung-Hyun Kim, Hyun Beom Song, Jeong Hun Kim, Ok-Seon Kwon, Kyung-Sook Chung

“…In this study, we generated iPSC lines from three patients diagnosed with XLRS, each carrying distinct pathogenic RS1 variant (c.421C > T, c.130_140del and c.214G > A). …”
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Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience by Alejandro Sanchez-Nadales, Miguel Treminio-Quezada, Hasan Abad, Jessica Navarro-Motta, Pamela Contreras-Chavez, Anil Kachru, Chae Chu

“…Coinfection with other respiratory pathogens and opportunistic infections are possible.…”
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Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance by Roberto Perniola

“…The autoimmune polyendocrine syndrome type 1 (APS-1) is a monogenic disease due to pathogenic variants occurring in the autoimmune regulator (AIRE) gene. …”
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Phytophthora Identification and Sampling in Citrus Nurseries by Jamie D. Burrow, Diane B. Bright, Tim D. Riley, Evan G. Johnson, James H. Graham

“… Phytophthora species are important soilborne, fungus-like pathogens that attack the root systems, trunk, and fruit of citrus trees at any age. …”
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Research progress on Haemophilus parasuis vaccines by Yu Duan, Yue Hao, Huapeng Feng, Jianhong Shu, Yulong He

“…It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other upper respiratory tract pathogens, causing heavy economic losses to the pig industry. …”
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The Role of MicroRNAs in Diabetic Nephropathy by Hao Wu, Lili Kong, Shanshan Zhou, Wenpeng Cui, Feng Xu, Manyu Luo, Xiangqi Li, Yi Tan, Lining Miao

“…In recent years, research on microRNAs (miRNAs) has become a hotspot because of their critical role in regulating posttranscriptional levels of protein-coding genes that may serve as key pathogenic factors in diseases. Several miRNAs were found to participate in the pathogenesis of DN, while others showed renal protective effects. …”
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An Overview of the Molecular Methods in the Diagnosis of Gastrointestinal Infectious Diseases by Muhammad Amjad

“…This review summarizes and discusses the availability, advantages, and disadvantages of molecular methods in the detection and identification of human gastrointestinal pathogens.…”
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