A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods by Daniela Hübscher, Sabine Rebs, Luis Haupt, Thomas Borchert, Celina Isabell Guessoum, Franziska Treu, Steffen Köhne, Andreas Maus, Mario Hambrecht, Samuel Sossalla, Ralf Dressel, Angela Uy, Mark Jakob, Gerd Hasenfuss, Katrin Streckfuss-Bömeke

“…This fast, cost-effective, robust, and reliable assay demonstrates the feasibility to use high-throughput PCR-based methods for detection of human pathogenic viruses in ps-iPSC lines that were generated with nongenome integrating reprogramming methods.…”
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Prevalence, antibiotic resistance patterns, and virulence factors of Staphylococcus aureus isolates associated with bovine mastitis in northern Bangladesh by Md. Mominul Islam, Md. Imran Hossain, Md. Sadequl Islam, Md. Golam Azam, Sajeda Sultana

“…Furthermore, PCR was utilized to explore the presence of virulence genes linked to the pathogenicity of S. aureus. Findings revealed that out of the sampled cases, 56 strains of S. aureus were isolated, indicating a prevalence rate of 46.66 % in cases of clinical mastitis. …”
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Colorectal carcinogenesis in the Lynch syndromes and familial adenomatous polyposis: trigger events and downstream consequences by Pål Møller, Aysel Ahadova, Matthias Kloor, Toni T. Seppälä, John Burn, Saskia Haupt, Finlay Macrae, Mev Dominguez-Valentin, Gabriela Möslein, Annika Lindblom, Lone sunde, Ingrid Winship, Gabriel Capella, Kevin Monahan, Daniel D. Buchanan, D. Gareth Evans, Eivind Hovig, Julian R. Sampson

“…Colorectal cancer (CRC) carcinogenesis in carriers of pathogenic APC (path_APC) and pathogenic mismatch repair gene (path_MMR) variants is initiated by a second hit affecting the corresponding wild-type allele. …”
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Adult hypophosphatasia presenting with recurrent acute joint pain by Hayao Yoshida, Takaaki Murakami, Atsubumi Ogawa, Takashi Sunouchi, Naoko Hidaka, Nobuaki Ito, Hiromi Murakami, Hidenori Kawasaki, Tomoyuki Akiyama, Katsumi Nakajima, Daisuke Yabe, Taizo Yamamoto

“…While the patient had no history of premature loss of primary teeth, fragility fractures, muscle weakness or abnormalities in growth, genetic testing revealed a likely pathogenic and a pathogenic heterozygous variant in the ALPL gene, i.e., c.979T>C (p.Phe327Leu) and c.1559del (p.Leu520Argfs), confirming HPP. …”
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Genetic characterization of a rare case of pheochromocytoma in a pulmonary transplant patient by Stéfanie Parisien-La Salle, Florence Perreault, Gilles Corbeil, Julie Morisset, Charles Poirier, Catherine Beauregard, Agnès Räkel, Marjorie Labrecque, Martine Tétreault, Martine Tétreault, Christian Cohade, Pasquale Ferraro, Isabelle Bourdeau

“…However, tumoral RNA sequencing unveiled activation of the HIF pathway.ConclusionWe describe a rare case of PCC in a pulmonary transplant recipient, with genetic analyses showing no germline pathogenic variants and no somatic variants in the EPAS1 gene. …”
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In Vitro Biological Activity of Beauveria bassiana, Beauveria peruviensis, and Metarhizium sp. against Hypothenemus hampei (Coleoptera: Curculionidae) by Beimer Chuquibala-Checan, Magdiel Torres-de la Cruz, Santos Leiva, Elgar Hernandez-Diaz, Karol Rubio, Malluri Goñas, Marielita Arce-Inga, Manuel Oliva-Cruz

“…Conidia production, Conidia viability, and pathogenicity against H. hampei were evaluated at three concentrations (1 × 105, 1 × 107, and 1 × 109 conidia/mL−1). …”
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A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient by Li Yang, Xingyu Wan, Ran Hua, Junhong Jiang, Baotian Wang, Rui Tao, De Wu

“…Conclusion This study identified a novel likely pathogenic GABRA2 extracellular domain variant in a Chinese family causing the DEE phenotype. …”
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A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability by Xiujuan Yang, Zhongzhi Gan, Xiaoling Guo, Xiang Huang, Juan Liu, Yingchun Zheng, Xiaoqiang Zhou, Jingli Lian, Yue Liu, Tingting Yang, Chao Li, Fenying Chen, Fei He, Xiangmin Xu, Yasi Zhou, Qian Liu, Xingkun Yang, Fu Xiong

“…Abstract Objectives The SOX5 gene has been identified as the pathogenic gene responsible for Lamb-Shaffer syndrome. …”
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The quality and technological parameters of milk obtained from dairy cows with subclinical mastitis by Magdalena Zalewska, Paulina Brzozowska, Magdalena Rzewuska, Ewelina Kawecka-Grochocka, Daria M. Urbańska, Tomasz Sakowski, Emilia Bagnicka

“…This study investigates the impact of various bacterial pathogens on the SCC, milk composition, and technological properties of milk samples from 302 clinically healthy Polish Holstein-Friesian cows kept under intensive rearing conditions. …”
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Continuously relapsing (for two years) course of diarrheal variant of IBS (<i>Clinical case</i>) by Ye. A. Poluektova, S. Yu. Kuchumova, A. A. Kurbatova, A. A. Sheptulin, O. S. Shifrin, V. T. Ivashkin

“…By the example of clinical case to show modern algorithm of diagnostics and choice of pathogenically proved treatment for patient with continuously relapsing course of irritable bowel syndrome (IBS).Key points. …”
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Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting by Salvador Figuereo, Sahra Isse Mohamed, Desalegn Takele, Abdulrahman M. Sheikh, Solomon Chane Abera, Ayni Muhiadin Mohamed, Mutaawe Lubogo, Hassan Mukhtar Abukar, Mary Joan Karanja, Sulaiman Bangura, Antoine Abou Fayad, Ali Haji Adam, Abdinasir Yusuf Osman, Sk Md Mamunur Rahman Malik

“…We describe how the country moved rapidly from no testing capability to molecular testing and genomic sequencing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogens. Methods We reviewed primary sources information as well as data and records from secondary sources from 1 January 2020 to 31 December 2023. …”
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Spray vaccination with a safe and bivalent H9N2 recombinant chimeric NDV vector vaccine elicits complete protection against NDV and H9N2 AIV challenge by Xiaoquan Wang, Jing Dai, Wenhao Yang, Yao Yao, Jin Zhang, Kaituo Liu, Xiaolong Lu, Ruyi Gao, Yu Chen, Jiao Hu, Min Gu, Shunlin Hu, Xiufan Liu, Xiaowen Liu

“…Abstract Newcastle disease virus (NDV) and H9N2 avian influenza virus (AIV) represent significant pathogenic risks to the poultry industry, leading to considerable economic losses. …”
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Growth, Reduction, and Survival of Bacteria on Melon Types by Thao P. Nguyen, Michelle D. Danyluk, Keith R. Schneider

“…This 45-page fact sheet highlights the research that has been done to provide insight on possible sanitation methods and their efficacy in decontaminating melon types of foodborne pathogens as well as natural microflora. Written by Thao P. …”
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[FE1091] Regulations Governing the Usage of Reclaimed Water as an Alternative Water Source for Agricultural Irrigation in Florida by Leticia Braune, Gulcan Onel, Tatiana Borisova, Pilar Useche

“…Reclaimed water from alternative sources can be used to help offset the demand for fresh surface water and groundwater in agriculture. To ensure that pathogenic or trace chemical constituents in reclaimed water do not pose a threat to human health and the environment, state and federal governments impose regulations governing reclaimed water use. …”
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The Florida Plant Diagnostic Network by Aaron J. Palmateer, Carrie L. Harmon, Amanda Hodges, Natalia Peres, Kuang Ren Chung, Pamela D. Roberts, Lyle Buss, William T. Crow, Jiannong Xin, Robert J. McGovern, James W. Kimbrough, Timur M. Momol

“…Momol, describes Florida's network of support for the rapid detection, diagnosis, and decision support for pathogens and other pests affecting Florida's agricultural and natural ecosystems. …”
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Nanophthalmos: A Review of the Clinical Spectrum and Genetics by Pedro C. Carricondo, Thais Andrade, Lev Prasov, Bernadete M. Ayres, Sayoko E. Moroi

“…Here, we review the definition of nanophthalmos, the clinical and pathogenic features of the condition, and the genetics of this disorder.…”
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Helminths and helminth communities of Chondrostoma nasus from the Danube River, northwestern Bulgaria by Zaharieva Radoslava G., Kirin Diana A., Zaharieva Petya G.

“…The helminth communities of the species at the level of the component communities and the infracommunities were analyzed for the first time in Bulgaria. Helminth species pathogenic to fishes and humans were found in the helminth communities of Ch. nasus.…”
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Uterine Microbiology of Healthy Cows and Cows That Develop Uterine Disease by Klibs N. Galvão

“…This 4-page fact sheet summarizes what is known about the pathogenic bacteria associated with metritis and endometritis. …”
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Shiga Toxin-Producing Escherichia coli: Detection, Differentiation, and Implications for Food Safety by William J. Zaragoza, Max Teplitski, Clifton K. Fagerquist

“…Even though most E. coli are benign or even beneficial members of our gut microbial communities, strains carrying Shiga-toxin encoding genes are highly pathogenic in humans and other animals. This 6-page fact sheet discusses the two types of Shiga toxins and the best approaches to identifying and determining which Shiga toxin is present. …”
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CPEO and Mitochondrial Myopathy in a Patient with DGUOK Compound Heterozygous Pathogenetic Variant and mtDNA Multiple Deletions by V. Montano, C. Simoncini, Cassi L. Calì, A. Legati, G. Siciliano, M. Mancuso

“…Here we report the case of a 42-year-old Italian woman presenting with a chronic progressive external ophthalmoplegia and myopathy with mtDNA multiple deletions and the compound heterozygous c.462T>A (p.Asn154Lys) and c.707+2T>G pathogenic variants in DGUOK.…”
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