Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning by D. E. Ivanoshchuk, A. B. Kolker, O. V. Timoshchenko, S. E. Semaev, E. V. Shakhtshneider

“…A negative result of genetic screening for pathogenic variants in genes of the low-density lipoprotein receptor and its ligands does not rule out a diagnosis of familial hypercholesterolemia. …”
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The theses for MD degree by article Editorial

“…Schyokotova — Clinical and laboratory parameters and endothelial dysfunction at liver diseases, their diagnostic, prognostic value and potential of application for treatment response rate ratingA.A. Kurbatova — Pathogenic and clinical value of cytokine and claudin system at irritable bowel syndromeYe.N. …”
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The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov

“…Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. …”
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Biopreservation of Shrimps Using Composed Edible Coatings from Chitosan Nanoparticles and Cloves Extract by Ahmed A. Tayel, Aml F. Elzahy, Shaaban H. Moussa, Mohammed S. Al-Saggaf, Amany M. Diab

“…The entire agents (Cht-NPs, CLE, and CLE/Cht-NPs) exhibited remarkable antibacterial activities toward all food-borne pathogens; CLE/Cht-NPs were significantly the most forceful. …”
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Dietary Fe-Gly supplementation attenuates enterotoxigenic Escherichia coli (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets by Qing Gao, Qing Gao, Qing Gao, Yilong Zhang, Yabin Wu, Dianchao Gu, Junzhou Chen, Conghui Yin, Hao Wu, Dan Zhu, Daiwen Chen, Aimin Wu

“…This decreases the iron available for pathogenic microorganisms in the gut, thereby inhibiting the proliferation of intestinal pathogens and ensuring the intestinal health of piglets.…”
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Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases by Mohamed Elbadawy, Nagisa Saito, Yuki Kato, Kimika Hayashi, Amira Abugomaa, Mio Kobayashi, Toshinori Yoshida, Makoto Shibutani, Masahiro Kaneda, Hideyuki Yamawaki, Kazuaki Sasaki, Tatsuya Usui, Tsutomu Omatsu

“…Abstract Bat is considered a natural reservoir of various important pathogens, including severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2, Ebola virus, and Nipah virus. …”
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Genomic characterization and evolutionary analysis of a Getah virus variant from piglets in central China by Zhenhua Guo, Yao Jiang, Peng Li, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang

“…The genomic characteristics and evolutionary relationship of the pathogenic viral strain were also analyzed.ResultsThe isolate GETV-HeN202309 shared the highest nucleotide identity of 99.8% with strains from Guangdong and Sichuan province, suggesting it is an imported transmission. …”
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The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin by Jin Zeng, Fuyang Song, Yi Yang, Chenjie Ma, Guangcun Deng, Yong Li, Yujiong Wang, Xiaoming Liu

“…However, studies of its pathogenic roles and functional mechanisms have been hampered due to the difficulty of purification and lack of specific antibodies against this toxin. …”
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High-Throughput 16 S rRNA Gene Sequencing Reveals Bacterial Diversity of Infant Formula Production Line Samples in Spring and Summer by Xian Li, Yongbo Li, Yalun Zhang, Rui Zhang, Hui Wang, Tao Zhang, Taotao Yan, Zilun Zhang, Guohua Shi, Wei Zhou

“…The potential bacterial pathogens were identified as Pseudomonas aeruginosa in spring and Acinetobacter baumannii in summer. …”
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Development and Application of <i>Lactobacillus plantarum</i> PSCPL13 Probiotics in Olive Flounder (<i>Paralichthys olivaceus</i>) Farming by Muhammad Aleem Abbas, Hae-Jung Kim, Ga-Yeong Lee, Hae-Yeon Cho, Syed Al Jawad Sayem, Eon-Bee Lee, Seung-Jin Lee, Seung-Chun Park

“…After screening 16 <i>Lactobacillus</i> isolates, PSCPL13 was selected because of its potential broad-spectrum antibacterial activity against many pathogens, such as <i>Vibrio</i> and <i>Edwardsiella</i>. …”
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Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

“…GNAO1-associated disorders are ultra-rare autosomal dominant conditions, which can manifest, depending on the exact pathogenic variant in GNAO1, as a spectrum of neurological phenotypes, including epileptic encephalopathy, developmental delay with movement disorders, or late-onset dystonia. …”
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Recent advancements in the diverse roles of polymerase-associated proteins in the replication and pathogenesis of Newcastle disease virus by Jinghang Zhou, Yuqi Duan, Menglan Liu, Jinyang Liu, Zenglei Hu, Zhiqiang Duan

“…Additionally, the interactions between these polymerase-associated proteins and host proteins are closely related to the NDV’s replication and pathogenicity. Despite significant progress in understanding the unique and shared functions of NDV polymerase-associated proteins, research on these viral proteins’ structure and function is less comprehensive than other NDV proteins, and the available information is often scattered. …”
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Silver Nanoparticles: Biosynthesis Using an ATCC Reference Strain of Pseudomonas aeruginosa and Activity as Broad Spectrum Clinical Antibacterial Agents by Melisa A. Quinteros, Ivana M. Aiassa Martínez, Pablo R. Dalmasso, Paulina L. Páez

“…This work demonstrates the first helpful use of biosynthesized Ag-NPs as broad spectrum bactericidal agents for clinical strains of pathogenic multidrug-resistant bacteria such as methicillin-resistant S. aureus, A. baumannii, and E. coli. …”
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Integrated assessment of mucilage impact on human health using the One Health approach: Prevalence and antimicrobial resistance profiles of Escherichia coli and Clostridium perfrin... by Artun Yibar, Hilal Ay, Fuat Aydin, Secil Abay, Emre Karakaya, Tuba Kayman, Cem Dalyan, Fatih Dogan Koca, Duygu Aydogdu, Nihed Ajmi, Muhammed Duman, Izzet Burcin Saticioglu

“…Seasonal and climatic factors influencing mucilage formation amplify its role in transmitting antimicrobial-resistant pathogens, posing significant risks to public and environmental health. …”
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A Rare Case of the Digenic Inheritance of Long QT Syndrome Type 2 and Type 6 by Annejet Heida, Lisette J. M. E. van der Does, Ahmed A. Y. Ragab, Natasja M. S. de Groot

“…Genetic testing identified a mutation of the KCNH2 gene and an unclassified variant, most likely pathogenic, of the KCNE2 gene. This digenic inheritance is extremely rare.…”
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Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report by Yixiao Wei, Chunlei Wang, Lingtao Chong, Xiaojing Cui

“…Conclusions There is potential association between Secukinumab, an IL-17A inhibitor, and NTM disease, echoing anti-TNF biologics’ NTM risk, indicating the urgent need for further research on pathogenic mechanisms and risk factors.…”
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Rain Barrel Water Quality in Florida by Kimberly Moore, Mica McMillan, Lorna Bravo

“…All water samples had low levels of nutrients and no detectable pathogens. Based on our analysis, the water collected from these rain barrels would be safe to use for non-potable uses in the landscape and garden. …”
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Preventing Foodborne Illness: Clostridium botulinum by Keith R. Schneider, Mickey E. Parish, Renée M. Goodrich, Taylor Cookingham

“…This document is FSHN04-06, one of a series of the Food Science and Human Nutrition Department discussing common foodborne pathogens of interest to food handlers, processors, and retailers; Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. …”
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Subacute Osteomyelitis of the Pediatric Talus: A First Report of Brodie’s Abscess from Morganella morganii by Mitchell C. Harris, Daniel C. DeRosa, Priscilla A. West

“…Brodie’s abscess is a subacute form of osteomyelitis which generally occurs in the metaphysis of the femur and tibia in the pediatric population. Pathogens are most commonly Gram-positive bacteria, notably Staphylococcus and Streptococcus. …”
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Pool Chemicals and Personal Safety by Fred Fishel

“…Pool chemicals containing chlorine safeguard against recreational-water illnesses caused by disease-causing pathogens, such as the diarrhea-causing Cryptosporidium. …”
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