Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function... by Shan-Shan Zhao, De-Liang Tao, Jin-Ming Chen, Ming-Yi Zhang, Xin Yang, Jun-Ke Song, Qun Liu, Guang-Hui Zhao

“…ABSTRACT Neospora caninum is one of the most common pathogens causing reproductive failure in ruminants (e.g., cattle and goats) worldwide. …”
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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

“…Pathogenic/likely pathogenic germline variants in the BRCA1 and BRCA2 genes are associated with an increased risk of developing cancer, particularly breast and/or ovarian tumors. …”
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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

“…The diagnostic tests currently available for tick-borne diseases are severely limited in their ability to provide accurate results and cannot detect multiple pathogens in a single run. The multiplex protein microarray developed at Vibrant was designed to detect multiple serological antibodies thereby detecting exposure to multiple pathogens simultaneously. …”
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Gut Microbiota-Immune System Crosstalk and Pancreatic Disorders by D. Pagliari, A. Saviano, E. E. Newton, M. L. Serricchio, A. A. Dal Lago, A. Gasbarrini, R. Cianci

“…In healthy states, there is a perfect balance between commensal and pathogens, and microbiota and the immune system interact to maintain gut homeostasis. …”
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Unravelling the interplay of nitrogen nutrition and the Botrytis cinerea pectin lyase BcPNL1 in modulating Arabidopsis thaliana susceptibility by Antoine Davière, Aline Voxeur, Sylvie Jolivet, Luka Lelas, Samantha Vernhettes, Marie-Christine Soulié, Mathilde Fagard

“…Using mutant strains lacking BcPNL1, we observed reduced pathogenicity, a delay in germination and a lag in triggering the plant defense response. …”
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Metabolic engineering approaches for the biosynthesis of antibiotics by Geunsoo Yook, Jiwoo Nam, Yeonseo Jo, Hyunji Yoon, Dongsoo Yang

“…Conclusion These metabolic engineering and synthetic biology strategies offer promising potential to revitalize the discovery and development of new antibiotics, providing renewed hope in humanity’s fight against MDR pathogenic bacteria.…”
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Recombinant human growth hormone treatment of Floating-Harbor syndrome: a case report and literature review by Qing He, Yi Deng, Lei Xu, Zhe Xu, Yi Ding, Menghui Wu

“…Whole exome sequencing (WES) detected a pathogenic variant (c.7303 C > T, p.R2435X) in the SRCAP gene of this patient, which is a denovo variant. …”
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Whole genome sequencing completes the molecular genetic testing workflow of patients with Lynch syndrome by Klaudia Horti-Oravecz, Anikó Bozsik, Tímea Pócza, Ildikó Vereczkey, Tamás Strausz, Erika Tóth, Tatiana Sedlackova, Diana Rusnakova, Tomas Szemes, István Likó, Edit Oláh, Henriett Butz, Attila Patócs, János Papp, Vince Kornél Grolmusz

“…Abstract Multigene panel tests (MGPTs) revolutionized the diagnosis of Lynch syndrome (LS), however noncoding pathogenic variants (PVs) can only be detected by complementary methods including whole genome sequencing (WGS). …”
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Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting by Sofiia N. Rizatdinova, Alina E. Ershova, Irina V. Astrakhantseva

“…The study of pathogenic viruses has always posed significant biosafety challenges. …”
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Recent Progress in Bioactive Substance Encapsulation System Based on Electrospinning and Its Application in Antimicrobial Food Packaging by REN Jie, TAN Zhongmei, TIAN Zihao, WU Gaoyun, LIU Yongchen, WANG Hao, JIANG Zhanmei, MA Jiage, HOU Juncai

“…The contamination of foods by foodborne pathogenic and spoilage microorganisms is one of the major causes of foodborne diseases. …”
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Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus by Lixin Zhang, Usha Reddi, Usha Srinivasan, Sheng Li, Stephanie M. Borchardt, Parvathy Pillai, Puja Mehta, Anne N. Styka, Joan DeBusscher, Carl F. Marrs, Betsy Foxman

“…Many bacterial species function as both commensals and pathogens; we used this dual nature to develop a high-throughput molecular epidemiological approach to identifying bacterial virulence genes. …”
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Trace metals induce microbial risk and antimicrobial resistance in biofilm in drinking water by Bowei Li, Ling Feng, Rakia Chouari, Sofia Samoili, Stefanos Giannakis

“…The overall exposure risk of antibiotic resistance genes (ARGs) increased, whereas Fe(III) enhanced the co-occurrence of ARGs and pathogens, potentially leading to serious hidden microbial risks. …”
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Western Blot as a Confirmatory Test for Lyme Disease by Harvey Artsob

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A Fatal Bloodstream Infection by Staphylococcus pettenkoferi in an Intensive Care Unit Patient by Caterina Mammina, Celestino Bonura, Maria Stella Verde, Teresa Fasciana, Daniela Maria Palma

“…Coagulase negative staphylococci are increasingly recognized as leading pathogens in bacteremia, with incidence peaking in intensive care units. …”
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Further Evidence That the CFTR Variant c.2620-6T>C Is Benign by Violet I. Wallerstein, Robert Wallerstein

“…We present an asymptomatic adult who has this variant as well as the well described delta F508 pathogenic variant in transpresentation. This patient provides additional evidence that this is a benign polymorphism.…”
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Grepafloxacin Clinical Program for Lower Respiratory Tract Infections by Arne C Rodloff

“…Unlike older quinolones, grepafloxacin has excellent activity against Gram-positive organisms, which include Streptococcus pneumoniae and “atypical” pathogens Legionella species. Mycoplasma pneumoniae and Chlamydia pneumoniae. …”
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Level of CYP4G19 Expression Is Associated with Pyrethroid Resistance in Blattella germanica by Guang-zhou Guo, Yi-jie Geng, Da-na Huang, Cai-fang Xue, Ren-li Zhang

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Antimicrobial Activity of <i>Zingiber Officinale</i> and <i>Allium Sativum</i> on some Drug Resistant Bacterial Isolates by S.E. Emmanuel, E.O. Ehinmitan, R.S. Bodunde, J.C. Joseph

“…Increasing multi-drug resistance of pathogens forces researchers to find alternative compounds for treatment of infectious diseases. …”
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The First case of Locally Acquired Tick-Borne Babesia Microti Infection in Canada by Jared MP Bullard, Arshad N Ahsanuddin, Anamarija M Perry, L Robbin Lindsay, Mahmood Iranpour, Antonia Dibernardo, Paul G Van Caeseele

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A Patient with Double-Negative VGKC, Peripheral Nerve Hyperexcitability, and Central Nervous System Symptoms: A Postinfectious Autoimmune Disease by Birte Eikeland

“…Research in the last few years has indicated that most voltage-gated potassium channel- (VGKC-) complex antibodies without leucine-rich glioma-inactivated protein 1 or contactin-associated protein-like 2 antibody specificity lack pathogenic potential and are not clear markers for autoimmune inflammation. …”
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