Cultivatable Bacteriota of Chronic Wound of Patients with Diabetic Foot Syndrome with Critical Limb Ischemia Based on Wound Biopsy in Peri-Revascularization Period by Syedah Sarah Hussaini, Fran Dominic Grubesa, Mateusz Gajda, Martyna Schönborn, Katarzyna Bogucka, Mikołaj Maga, Paweł Maga, Jadwiga Wójkowska-Mach

“…Quantitative reduction was obtained in four (17.4%) cases. Pathogen distribution at follow-up resembled baseline findings. …”
Get full text

Genomic characterization and radiation tolerance of Naganishia kalamii sp. nov. and Cystobasidium onofrii sp. nov. from Mars 2020 mission assembly facilities by Patrick Leo, Marcus de Melo Texeira, Atul M. Chander, Nitin K. Singh, Anna C. Simpson, Andrey Yurkov, Fathi Karouia, Jason E. Stajich, Christopher E. Mason, Kasthuri Venkateswaran

Get full text

Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China by Hongli An, Xiamei Kang, Chenhu Huang, Chenghao Jia, Jiaqi Chen, Yingying Huang, Qianzhe Cao, Yan Li, Biao Tang, Min Yue

“…Salmonella, a common zoonotic pathogen, is a significant concern for public health, particularly when it contaminates animal-borne products. …”
Get full text

Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…In contrast, neutrophils exposed to non-citrullinated vimentin exhibited higher efficiency in favoring pathogen phagocytosis, such as Escherichia coli and Candida albicans, compared to CitVim. …”
Get full text

Virulence changes in Vibrio parahaemolyticus during the freezing of Penaeus chinensis by Zenghui Gao, Heer Ding, Ke Li, Qiang Zhang, Xubo Zhao, Liu Bin, Tianli Yue

“…Although Vibrio parahaemolyticus has become the most common pathogen in fresh and frozen seafood, its virulence changes have often been ignored during the processing of seafood. …”
Get full text

Rapid diagnostic testing combined with an immediate infectious disease consultation increases the rate of septic intensive care unit patients on targeted antibiotic therapy by Evelyn Kramme, Nadja Käding, Nadja Käding, Tobias Graf, Karolin Schmoll, Heidi Linnen, Katharina Nagel, Esther Grote-Levi, Susanne Hauswaldt, Dennis Nurjadi, Dennis Nurjadi, Jan Rupp, Jan Rupp, Jan Rupp

“…The control group underwent routine laboratory testing, and for the intervention group, RDT was applied with immediate ID consultation.ResultsIn 77 out of the 91 patients in the intervention group, the pathogen was identified by RDT. Regarding antimicrobial susceptibility testing (AST), genotypic testing (ePlex®) was successful for Gram-positive cocci, but inadequate for Gram-negative rods. …”
Get full text

Virulence profile of carbapenem-resistant Klebsiella pneumoniae strains by an in vivo model of Galleria mellonella by María Guembe, Rama Hafian, Marta Díaz-Navarro, Andrés Visedo, Flavio De Maio, Fulvia Pimpinelli, Ilaria Cavallo, Mauro Truglio, Francesca Sivori, Enea Gino Di Domenico

“…ABSTRACT Klebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. …”
Get full text

A new method for detecting mixed Mycobacterium tuberculosis infection and reconstructing constituent strains provides insights into transmission by Benjamin Sobkowiak, Patrick Cudahy, Melanie H. Chitwood, Taane G. Clark, Caroline Colijn, Louis Grandjean, Katharine S. Walter, Valeriu Crudu, Ted Cohen

“…Abstract Background Mixed infection with multiple strains of the same pathogen in a single host can present clinical and analytical challenges. …”
Get full text

Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase by Valeriya Bezkorovayna, Brooke K. Hayes, Francesca N. Gillett, Amy Wright, David I. Roper, Marina Harper, Sheena McGowan, John D. Boyce

“…ABSTRACT Acinetobacter baumannii is a Gram-negative opportunistic pathogen and is a common cause of nosocomial infections. …”
Get full text

Assessment of physiological status of felids as indicator of their welfare in the wild by Ekaterina V. Pavlova, Evgeny A. Ivanov, Vadim E. Kiriluk, Vyacheslav V. Rozhnov

“…Occurrence of seropositive reactions to 12 different pathogens was analyzed in all the animals after the hematological analysis. …”
Get full text

The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection by Lyudmila V. Lyubimova, Svetlana I. Pavlova, Nikolay S. Nikolaev, Evgeniy A. Lyubimov, Nadezhda N. Pchelova, Vladimir Y. Emelianov

“…Diagnostics of infectious complications in joint replacement surgery remains a significant challenge, particularly when microbiological analysis of biological material fails to reveal pathogen growth. The aim of the study was to determine threshold values for C-reactive protein, interleukin-6, and presepsin levels, and to assess their diagnostic value in detecting periprosthetic joint infection. …”
Get full text

Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment by Sunisa Khongthong, Pipat Piewngam, Natthrit Roekngam, Prapot Maliwan, Sonsawan Kongpuckdee, Juthatip Jeenkeawpleam, Prawit Rodjan

“…HS impacts gut health by causing damaged mucosal microstructures, increased oxidative stress, weakened immunity, and heightened permeability to toxins and poultry pathogens. We investigated the potential benefits to broiler chickens subjected to HS of dietary supplementation with Bacillus subtilis 14823. …”
Get full text

Mycobacteria Exploit Host GPR84 to Dampen Pro-Inflammatory Responses and Promote Infection in Macrophages by Reziya Wumaier, Ke Zhang, Jing Zhou, Zilu Wen, Zihan Chen, Geyang Luo, Hao Wang, Juliang Qin, Bing Du, Hua Ren, Yanzheng Song, Qian Gao, Bo Yan

“…As a highly successful pathogen, <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) has evolved numerous strategies to evade host immune responses, making it essential to understand the interactions between <i>Mtb</i> and host cells. …”
Get full text

Biocontrol of gray spot disease on Polygonatum cyrtonema Hua by Bacillus velezensis GX1 by L. Sun, G.L. Deng, H.L. Wu, Q. He, S.H. Hu, J.Y. Li, X.Y. Li, S. Meng, A.N. He, Y.Q. Tian, X. Chen, S.H. Li

“…Results indicated that GX1 effectively inhibited P. xuefengensis HJHB1, inhibiting growth of the pathogen by 74.97 % in vitro and inhibiting disease development by 87.13 % in field experiments. …”
Get full text

A novel virulent core genome multilocus sequence type CT 11424 of Listeria monocytogenes isolate causing stillbirth in Bangladesh by Muntasir Alam, Md Saiful Islam, M. Ishrat Jahan, Arpita Shyama Deb, Afruna Rahman, Zahidul Islam, Atique Iqbal Chowdhury, Kazi Munisul Islam, Mohammad Zahid Hossain, Dilruba Ahmed, Shams El Arifeen, Emily S. Gurley, Mustafizur Rahman

“…Abstract Background Listeria monocytogenes is a foodborne pathogen that can lead to severe pregnancy outcomes. …”
Get full text

Genome drafting of nosocomial infection CRE Klebsiella pneumoniae confirming resistance to colistin and eravacycline, carrying blaNDM-1, mcr-1, and blaKPC-2, in neonatology from No... by Xinlong Zhou, Kailash Wagh, Guizhen Lv, Devender Sharma, Wei Lei

“…BackgroundCarbapenem-resistant Klebsiella pneumoniae (CRKP) is a critical pathogen in healthcare settings, associated with high mortality due to its extensive antibiotic resistance. …”
Get full text

First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand by Nattarika Chaichana, Thunchanok Yaikhan, Mingkwan Yingkajorn, Nonthawat Thepsimanon, Sirikan Suwannasin, Kamonnut Singkhamanan, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Komwit Surachat

“…Therefore, this study provides valuable insights into the genomic features, antibiotic resistance, and potential pathogenicity of M. phragmitis PSU-3885–11. The findings also emphasize the importance of continued surveillance and genomic analysis of environmental bacteria that may emerge as opportunistic pathogens in human infections.…”
Get full text

Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains by Chidiebere Akusobi, Sanjeevani Choudhery, Bouchra S. Benghomari, Ian D. Wolf, Shreya Singhvi, Thomas R. Ioerger, Eric J. Rubin

“…ABSTRACT Mycobacterium abscessus (Mab) is a clinically significant pathogen and a highly genetically diverse species due to its large accessory genome. …”
Get full text

MsCL-P1: A multifunctional C-type lectin from largemouth bass (Micropterus salmoides) with broad microbe binding and agglutination activities by Siyi She, Ying Ye, Fengyao Guo, Shun Yang, Mengmeng Huang, Hui Fei

“…The recombinant CRD of MsCL-P1 (rCRD) demonstrated binding activity to various pathogen-associated molecular patterns (PAMPs), including lipopolysaccharide (LPS), peptidoglycan (PGN), and glucan (GLU), as determined by ELISA. …”
Get full text

Bacterial Diversity in Native Heart Valves in Infective Endocarditis by Anna Sinitskaya, Alexander Kostyunin, Maxim Asanov, Maria Khutornaya, Anastasia Klyueva, Alyona Poddubnyak, Alexey Tupikin, Marsel Kabilov, Maxim Sinitsky

“…Improving the identification of pathogens that cause IE is important to increase the effectiveness of its therapy and reduce the mortality caused by this pathology. …”
Get full text