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141
Evaluating the Effectiveness of Zero Trust Architecture in Protecting Against Advanced Persistent Threats
Published 2024-12-01“…As a paradigm shift in network security, the idea of Zero Trust Architecture has attracted a lot of attention recently. …”
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142
Biomimic models for in vitro glycemic index: Scope of sensor integration and artificial intelligence
Published 2025-01-01“…This technological convergence represents a paradigm shift in food science analytics, promising improved throughput and precision in GI assessment. …”
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143
Assessing Human Factors in Virtual Reality Environments for Industry 5.0: A Comprehensive Review of Factors, Metrics, Techniques, and Future Opportunities
Published 2025-01-01“…Industry 5.0, the latest evolution in industrial processes, builds upon the principles of Industry 4.0 by emphasizing human-centric approaches and the integration of virtual reality technologies. This paradigm shift underscores the importance of collaboration between humans and advanced technologies with a focus on optimizing efficiency, safety, and worker skill development. …”
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144
PPARγ and the Innate Immune System Mediate the Resolution of Inflammation
Published 2015-01-01“…Resolution represents not only an increase in anti-inflammatory actions, but also a paradigm shift in immune cell function to restore homeostasis. …”
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145
Navigating the Challenges of Sustainability in the Food Processing Chain: Insights into Energy Interventions to Reduce Footprint
Published 2025-01-01“…In light of the projected population growth and increasing food demand, the study advocates for a paradigm shift towards more sustainable and resilient food production practices, adopting energy-efficient technologies, promoting sustainable dietary habits, and strengthening global cooperation among stakeholders to achieve the Sustainable Development Goals. …”
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146
Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries
Published 2025-01-01“…By addressing these gaps, this review provides new insights and calls for a paradigm shift toward a more context-specific and integrative approach to developing targeted therapies for psychological dysfunction following brain injuries.…”
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147
When is synthetic sufficient? Ethical considerations and alternatives in simulation-based ultrasound education
Published 2025-01-01“…The involvement of knowledge or end-user engagement, along with evidence-based design solutions, is crucial to catalyse a paradigm shift in a discipline deeply entrenched in tradition. …”
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148
Monitoring and management of adverse effects associated with trastuzumab deruxtecan: a UAE-specific consensus
Published 2025-01-01“…The recognition of “HER2-low” expression as a targetable category has caused a paradigm shift in the management of breast cancer. Although initially developed to target HER2-positive breast cancer, trastuzumab deruxtecan (T-DXd), an ADC, has now also been approved to treat metastatic or unresectable HER2-low breast cancers. …”
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149
Learning through “Research Cognitive Theory”: A new framework for developing 21st century research skills in secondary school students
Published 2025-01-01“…Drawing on a novel framework of “Research Cognitive Theory” (RCT) and empirical evidence, the HSRCLP represents a paradigm shift in secondary education, offering a dynamic research learning environment to enculturate research skills in students. …”
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150
Natural science education in the university core curriculum
Published 2024-04-01“…Against the backdrop of a paradigm shift in education, universities are transitioning to individual educational trajectories to accommodate the needs of an individual in the process of continuous professional development. …”
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151
Mitigation of human factor in tomographic post processing of additive manufactured critical parts for aviation application
Published 2025-02-01“…Simultaneously to the development of AM fabrication, tomographic systems have also adapted to meet the needs of application-dependent inspection: from micro-focus and nano-focus systems for finding micrometre-sized discontinuities, to linear accelerators for inspecting large components built in high-density alloys, the current range of machinery allows for traversing and inspecting current production by filling the gap generated by the manufacturing paradigm shift. However, it is critical to analyse the effort that is required to the technical personnel responsible for analysing tomographic data for NDT applications. …”
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152
Advancing Alzheimer's Therapy: Computational strategies and treatment innovations
Published 2025-06-01“…Overall, integrating computational methodologies represents a promising paradigm shift in AD therapeutics, offering innovative solutions to overcome existing challenges and transform the landscape of AD treatment.…”
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153
Integrated Management of Cardiovascular–Renal–Hepatic–Metabolic Syndrome: Expanding Roles of SGLT2is, GLP-1RAs, and GIP/GLP-1RAs
Published 2025-01-01“…By synthesizing evidence from landmark clinical trials, we highlight the paradigm-shifting potential of these therapies. SGLT2is, such as dapagliflozin and empagliflozin, have emerged as cornerstone guideline-directed treatments for heart failure (HF) and chronic kidney disease (CKD), providing benefits that extend beyond glycemic control and are independent of diabetes status. …”
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154
Producing 100+ MPa Field Concrete in Developing Countries: Requirements and Challenges
Published 2024-12-01“… Over the past three decades, there has been a paradigm shift in the concrete industry in which high strength and high performance concrete became more widely in use. …”
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155
Museomics of Carabus giant ground beetles shows an Oligocene origin and in situ alpine diversification
Published 2024-08-01“…The development of museomics represents a major paradigm shift in the use of natural history collection specimens for systematics and evolutionary biology. …”
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156
Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes
Published 2013-01-01“…Implementation of these defined regulatory T cell epitopes for therapy of T1D and other autoimmune diseases may lead to a paradigm shift in disease management.…”
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157
Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment...
Published 2013-01-01“…These dramatic findings indicate that TNFα can turn into a strong prometastatic factor, suggesting a paradigm shift in which clinically approved inhibitors of TNFα would be applied in breast cancer therapy.…”
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158
Amyloids in bladder cancer hijack cancer-related proteins and are positive correlated to tumor stage
Published 2025-02-01“…This underscores the necessity for a paradigm shift in the approach to bladder cancer. The role of amyloids in cancer remains unclear despite their identification in several other pathologies. …”
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159
Science-based communication and education needed to improve forest carbon science, policy, and management outcomes
Published 2025-01-01“…Because forests stand to play a significant role in reaching net-zero emission targets, politicians and policymakers must act decisively to engineer a rapid paradigm shift that maintains forests’ resilience and adaptive capacity. …”
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160
A cycle of invisibilisation: a qualitative study of Brazilian health system factors shaping access to long COVID care
Published 2024-12-01“…Doing so offers wider benefits beyond patients with LC. We call for a paradigm shift in clinical approaches to IACCs.…”
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