Real-world clinical experience with secukinumab in psoriatic arthritis: an observational study and a literature review by Eleonora Celletti, Giulio Gualdi, Emanuela Sabatini, Francesco Cipollone, Fabio Lobefaro, Paolo Amerio

“…For the review of the literature, 35 articles were identified but only 17 papers were eventually considered. Conclusions. …”
Get full text

Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis by Piotr Wojdasiewicz, Pawel Turczyn, Barbara Dobies-Krzesniak, Justyna Frasunska, Beata Tarnacka

“…Regarding the fact that acting against the CX3CL1/CX3CR1 axis is a potential target of immune treatment in osteoporosis, the number of available papers tackling the topic is certainly insufficient. …”
Get full text

Role of digital technology in epidemic control: a scoping review on COVID-19 and Ebola by Amanuel Adugna, Gossa Fetene Abebe, Desalegn Girma, Melsew Setegn Alie, Tewodros Yosef, Daniel Asmelash, Dorka Dessalegn

“…Objective To synthesise the role of digital technologies in epidemic control and prevention, focussing on Ebola and COVID-19.Design A scoping review.Data sources A systematic search was done on PubMed, HINARI, Web of Science, Google Scholar and a direct Google search until 10 September 2024.Eligibility criteria We included all qualitative and quantitative studies, conference papers or abstracts, anonymous reports, editorial reports and viewpoints published in English.Data extraction and synthesis The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews checklist was used to select the included study. …”
Get full text

Reengineering of the organizational structure and business processes of investment and construction activities. Their place in the general system of corporate regulation by S. B. Sborshikov, N. V. Lazareva

“…The information base of the research was the scientific search carried out by the authors earlier, which was reflected in published papers on this subject. Additional sources were scientific works of domestic and foreign scientists, as well as practical materials.Results. …”
Get full text

Lower Kinetic Chain, Meet the Thinking Brain: A Scoping Review of Cognitive Function and Lower Extremity Injury Risk by Michaela A. Reyes, Mark O. Probasco, Trina N. Worby, Dylan E. Loertscher, Lyndsey K. Soderbeck, Wendy E. Huddleston

“…Inclusion criteria included papers written in English published between 2000-2021. …”
Get full text

Research hotspots and frontiers in the tumor microenvironment of colorectal cancer: a bibliometric study from 2014 to 2024 by Xinran He, Tingyi Xie, Li Shi, Xuyi Kuang, Lei Li, Xingyu Shang, Bo Fu

“…Elkord, Eyad is the most prolific author, and Frontiers in Immunology is the journal that published the most papers on the TME of CRC. In addition, keyword and cluster analysis showed that immune checkpoint inhibitors, cancer-associated fibroblasts, macrophage polarization, intestinal microbiota, colorectal cancer liver metastasis, drug resistance, scRNA-seq, etc. may be the research hotspots and trends in this field.ConclusionsColorectal cancer and tumor microenvironment research is in the developmental stage, and strengthening international cooperation can help to drive this field forward. …”
Get full text

Individual participant data meta-analysis of trials comparing frozen versus fresh embryo transfer strategy (INFORM): a protocol by Lan N Vuong, Rui Wang, Ben W Mol, Rong Li, Karin Hammarberg, Kate Brian, Yun Sun, Pollyanna Hardy, Anja Pinborg, Siladitya Bhattacharya, Sacha Stormlund, David J McLernon, Zi-Jiang Chen, Richard S Legro, Carlos Simon, Shimona Lai, Marian G Showell, Daimin Wei, Ze Wang, Keliang Wu, Xavier Santamaría, Christophe Blockeel, Femke Mol, Anna P Ferraretti, Bruce S Shapiro, Forest C Garner, Christos A Venetis, Abha Maheshwari, Gwenda Burns

“…We will also check reference lists of relevant papers. The search was performed on 23 September 2020 and will be updated. …”
Get full text

Therapeutic effects of cyclophosphamide, dsDNA preparations and combinations thereof against Krebs-2 ascites cancer cells and various cancer transplants by E. A. Potter, E. V. Dolgova, A. M. Minkevich, Ya. R. Efremov, O. S. Taranov, V. V. Omigov, V. P. Nikolin, N. A. Popova, A. S. Proskurina, E. I. Vereschagin, A. V. Kozel, V. A. Rogachev, D. B. Petrov, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…The present work is the first report in the series of papers from our group where we describe the development of anticancer therapy based on the selective targeting of TISCs. …”
Get full text

Constructing a metadata knowledge graph as an atlas for demystifying AI pipeline optimization by Revathy Venkataramanan, Revathy Venkataramanan, Aalap Tripathy, Tarun Kumar, Sergey Serebryakov, Annmary Justine, Arpit Shah, Suparna Bhattacharya, Martin Foltin, Paolo Faraboschi, Kaushik Roy, Amit Sheth

“…To address this issue, we propose to source AI pipeline metadata from open-source platforms such as Papers-with-Code, OpenML, and Hugging Face. However, integrating and unifying the varying terminologies and data formats from these diverse sources is a challenge. …”
Get full text

IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET [version 2; peer review: 2 approved] by Tamara Saksida, Alessia di Flora, Marina Romero-Ramos, Vladimirs Pilipenko, Laura Muñoz Delgado, Franca Marino, Yasemin Gursoy Ozdemir, Neda Nikolovski, Cristoforo Comi, Dale Lawson, Inês Figueira, Mitilda Gugu, Simona Poletti, Shubhra Acharya, Dogukan Pira

“…Through meetings, training schools, webinars, position papers, and review manuscripts, IMMUPARKNET will lead fruitful exchanges of know-how among experts in the field. …”
Get full text

CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

“…When reporting the results of EPDF trials, authors are encouraged to consult the CONSORT-DEFINE E&E document, together with the CONSORT and CONSORT-DEFINE statement papers, and adhere to their recommendations. Widespread adoption of the CONSORT-DEFINE statement is likely to enhance the reporting quality of EPDF trials, thus facilitating the peer review of such studies and their appraisal by researchers, regulators, ethics committee members, and funders. …”
Get full text

Production of subtilisin proteases in bacteria and yeast by A. S. Rozanov, S. V. Shekhovtsov, N. V. Bogacheva, E. G. Pershina, A. V. Ryapolova, D. S. Bytyak, S. E. Peltek

“…Despite longstanding applications of microbial proteases and a large number of research papers, the search for new protease genes, the construction of producer strains, and the development of methods for their practical application are still relevant and important, judging by the number of citations of the research articles on proteases and their microbial producers. …”
Get full text

Outcome and complications in postcardiotomy cardiogenic shock treated with extracorporeal life support – a systematic review and meta-analysis by Romana Maria Kienlein, Ralf Felix Trauzeddel, Nilufar Akbari, Leonello Avalli, Fausto Biancari, Carlotta Sorini Dini, Sabina Guenther, Christian Hagl, Matthias Heringlake, Jochen Kruppa, Timo Mäkikallio, Raphael Martins, Marc Pineton de Chambrun, Ardawan Julian Rastan, Antonio Rubino, Floris van den Brink, Michael Nordine, Sascha Treskatsch

“…Results Two thousand, seven hundred seventy-four papers were screened, of which 132 full text articles were assessed for suitability. 70 remaining studies were included for further evaluation and data analysis. …”
Get full text

Impact of COVID-19 and other pandemics and epidemics on people with pre-existing mental disorders: a systematic review protocol and suggestions for clinical care by Nitika Sanger, Stephanie Sanger, Lehana Thabane, Zainab Samaan, Lawrence Mbuagbaw, Tea Rosic, Anjali Sergeant, Emma Alaine van Reekum, Alexander Dufort, Sandra Lubert

“…Given the potential implications of the current pandemic measures (ie, disruption of healthcare services) on mental health, we will also compile a list of existing mental health resources.Ethics and dissemination No ethical approval is required for this protocol and proposed systematic review as we will only use data from previously published papers that have themselves received ethics clearance and used proper informed consent procedures.Systematic review registration PROSPERO registration number: CRD42020179611.…”
Get full text

What is the relationship between exposure to environmental pollutants and severe mental disorders? A systematic review on shared biological pathways by Pierluigi Catapano, Mario Luciano, Salvatore Cipolla, Daniela D'Amico, Alessandra Cirino, Maria Chiara Della Corte, Gaia Sampogna, Andrea Fiorillo

“…For this reason, only studies dealing with biomarkers or biological pathways were taken into account. The 47 papers included in the review were divided into two groups: those conducted on human participants (15 studies) and those utilizing animal models (31 studies); one study included both humans and animals. …”
Get full text

Avoiding ‘second victims’ in healthcare: what support do staff want for coping with patient safety incidents, what do they get and is it effective? A systematic review by Reema Harrison, Rebecca Lawton, Ruth Simms-Ellis, Raabia Sattar, Elizabeth Sweeting, Hannah Hartley, Matthew Morys-Edge

“…This review aims to determine what support healthcare professionals want for coping with PSIs, what support interventions/approaches are currently available and which have evidence for effectiveness.Design Systematic research review with narrative synthesis.Data sources Medline, Scopus, PubMed and Web of Science databases (from 2010 to mid-2021; updated December 2022), reference lists of eligible articles and Connected Papers software.Eligibility criteria for selecting studies Empirical studies (1) containing information about support frontline healthcare staff want before/after a PSI, OR addressing (2) support currently available, OR (3) the effectiveness of support to help prevent/alleviate consequences of a PSI. …”
Get full text

Meta-Analysis of the Effect of Resistance Exercise Prescription on Glucose and Lipid Metabolism in Overweight and Obese Adults by SUN Yuxin, GUO Xiaoyuan, CHEN Shi, PAN Hui, ZHU Huijuan

“…The literature was screened by 2 researchers according to inclusion and exclusion criteria and relevant data were extracted.Meta-analysis of included literature was performed using RevMan 5.3 software, and publication bias was assessed using funnel plots.ResultsA total of 17 papers and 700 study subjects were included, with 351 cases in the test group, and 349 cases in the control group.Meta-analysis results showed that compared with the control group, the glycosylated hemoglobin of the test group with resistance exercise[SMD (95% CI) =-0.30(-0.53--0.07), P=0.010], fasting blood glucose[SMD (95% CI)=-0.58(-0.90--0.26), P < 0.001], insulin resistance index[SMD (95% CI) =-0.90 (-1.42--0.38), P < 0.001], and low-density lipoprotein cholesterol (LDL-C)[SMD (95% CI) =-0.28 (-0.53--0.04), P=0.020] levels were reduced.Subgroup analysis showed that the glucose metabolism levels of the test group with only resistance exercise and a combination of resistance-anaerobic exercise were significantly lower than those of the control group(both P < 0.05).The heterogeneity of the effect of resistance exercise on glucose metabolism in Asian populations(I2=57%) was smaller than that in Caucasion(I2=76%) and other populations(I2=94%), and the level of decrease in glucose metabolism indexes was significant[SMD(95% CI)=-1.15(-1.73--0.57), P < 0.001].ConclusionResistance exercise can significantly reduce the level of glycolipid metabolism indexes in overweight or obese people.…”
Get full text

The association between age of menopause and type 2 diabetes: a systematic review and meta-analysis by Mansoureh Yazdkhasti, Kyana Jafarabady, Arman Shafiee, Samira Parvizi Omran, Zohre Mahmoodi, Sara Esmaeilzadeh, Touran Bahrami Babaheidari, Kourosh Kabir, Maral Peisepar, Mahmood Bakhtiyari

“…We pooled the effect sizes of the included studies using both adjusted odds ratios (OR) and hazard ratios (HR) of interest outcomes with their 95% confidence interval (CI). Results Nineteen papers were included in this study, 8 studies were cohorts, and 11 were cross sectional. …”
Get full text

Current methodologies of creating material passports: A systematic literature review by Ioannis Markou, Derek Sinnott, Ken Thomas

“…An initial search yielded 549 papers (2019 –2024 ), reduced to 33 after rigorous screening. …”
Get full text

Parental Technoference and Child Problematic Media Use: Meta-Analysis by Jinghui Zhang, Qing Zhang, Bowen Xiao, Yuxuan Cao, Yu Chen, Yan Li

“…Exclusion criteria included studies focusing on other child outcomes, having sample sizes <30, or being case reports or review papers. The risk of bias was assessed using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. …”
Get full text