miR-301a-mediated crosstalk between the Hedgehog and HIPPO/YAP signaling pathways promotes pancreatic cancer by Bing Qi, Yuqiong Wang, Xian Zhu, Yanfang Gong, Jing Jin, Hongyu Wu, Xiaohua Man, Feng Liu, Wenzhu Yao, Jun Gao

“…Immunohistochemical and molecular analyses confirmed dysregulation of pathway components in pancreatic cancer, underscoring the pivotal role of miR-301a. …”
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An exploratory study of serum creatine kinase as a prognostic marker for patients with resectable pancreatic cancer: looking into the relationship with body composition by Cong Chen, Xin Luo, Xianchao Lin, Ronggui Lin, Yuanyuan Yang, Congfei Wang, Haizong Fang, Tianhong Teng, Heguang Huang, Fengchun Lu

Subjects: “…Pancreatic cancer…”
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18F−Prostate−Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN−2): a phase I/II study by Jisce R. Puik, Thomas T. Poels, Gerrit K. J. Hooijer, Matthijs C. F. Cysouw, Joanne Verheij, Johanna W. Wilmink, Elisa Giovannetti, Geert Kazemier, Arantza Farina Sarasqueta, Daniela E. Oprea-Lager, Rutger-Jan Swijnenburg

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US-guided high-intensity focused ultrasound in pancreatic cancer treatment: a consensus initiative between Chinese and European HIFU centers by Kun Zhou, Holger Strunk, Dobromir Dimitrov, Joan Vidal-Jove, Maria A. Gonzalez-Carmona, Markus Essler, Chengbin Jin, Zhechuan Mei, Hui Zhu, Milka Marinova

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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

“…Human and mouse primary pancreatic cancer cell lines were used for in vitro assessment of cancer characteristics. …”
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Cancer-associated fibroblasts promote pro-tumor functions of neutrophils in pancreatic cancer via IL-8: potential suppression by pirfenidone by Tomohiko Yagi, Shunsuke Kagawa, Shohei Nogi, Atsuki Taniguchi, Masashi Yoshimoto, Kanto Suemori, Yasuo Nagai, Shuto Fujita, Shinji Kuroda, Satoru Kikuchi, Yoshihiko Kakiuchi, Fuminori Teraishi, Kosei Takagi, Toshiaki Ohara, Hiroshi Tazawa, Toshiyoshi Fujiwara

“…PFD suppresses IL-8 secretion from CAF-stimulated neutrophils and mitigates the malignant traits of pancreatic cancer cells. Conclusion CAFs activate neutrophils and enhance the malignant phenotype of pancreatic cancer. …”
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CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance by Dijie Zheng, Yazhu Deng, Lu Deng, Zhiwei He, Xinghao Sun, Yanyu Gong, Binbin Shi, Deqin Lu, Chao Yu

“…Abstract Cell division cycle associated 7 (CDCA7) plays a role in various malignancies, especially pancreatic cancer (PC). However, its expression pattern and functional significance in PC require further research. …”
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Immunotargeting of Integrin αβ for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model by Winn Aung MBBS, PhD, Atsushi B. Tsuji PhD, Hitomi Sudo PhD, Aya Sugyo M.Ed, Takako Furukawa PhD, Yoshinori Ukai PhD, Yoshikazu Kurosawa PhD, Tsuneo Saga MD, PhD

“…To explore suitable imaging probes for early and specific detection of pancreatic cancer, we demonstrated that α 6 β 4 integrin is a good target and employed single-photon emission computed tomography (SPECT) or near-infrared (NIR) imaging for immunotargeting. …”
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Assessment of safety and patency of 7-mm covered metal stents for preoperative biliary drainage in pancreatic cancer: Prospective multicenter study by Hirotoshi Ishiwatari, Yousuke Kobayashi, Shinya Kawaguchi, Takuji Iwashita, Junichi Kaneko, Jun Ito, Kazuma Ishikawa, Junya Sato, Fumitaka Niiya, Shinya Endo, Tatsunori Satoh, Shinya Uemura, Keita Mori

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Gastrojejunal Anastomosis Perforation after Gastric Bypass on a Patient with Underlying Pancreatic Cancer: A Case Report and Review of the Literature by Omar Bellorin, Anna Kundel, Alexander Ramirez-Valderrama, Armando Castro

“…We describe a case of gastrojejunal anastomosis perforation after gastric bypass on a patient with underlying pancreatic cancer. Case Description. A 54-year-old female with past surgical history of gastric bypass for morbid obesity and recent diagnosis of unresectable pancreatic cancer presents with abdominal pain, peritonitis, and sepsis. …”
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Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines by Valerio Pazienza, Francesca Tavano, Massimo Francavilla, Andrea Fontana, Fabio Pellegrini, Giorgia Benegiamo, Vincenzo Corbo, Fabio Francesco di Mola, Pierluigi Di Sebastiano, Angelo Andriulli, Gianluigi Mazzoccoli

“…Aim of our study was to assess the periodicity of PPARγ and DNMTs in pancreatic cancer (PC). We investigated the time-related patterns of PPARG, DNMT1, and DNMT3B expression monitoring their mRNA levels by qRT-PCR at different time points over a 28-hour span in BxPC-3, CFPAC-1, PANC-1, and MIAPaCa-2 PC cells after synchronization with serum shock. …”
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Tumor-Derived Exosomal miR-29b Reduces Angiogenesis in Pancreatic Cancer by Silencing ROBO1 and SRGAP2 by Lihua Wang, Lei Yang, Tingting Zhuang, Xiuqing Shi

“…However, its exact function and underlying mechanism during pancreatic cancer (PC) have not been investigated. Methods. …”
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β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis by Yijia Zhang, Xinya Zhu, Liyuan Chen, Tianyu Gao, Guang Chen, Jin Zhu, Guoyu Wang, Daiying Zuo

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Immunotherapeutic Potential of the Yellow Fever Virus Vaccine Strain 17D for Intratumoral Therapy in a Murine Model of Pancreatic Cancer by Alina S. Nazarenko, Yulia K. Biryukova, Kirill N. Trachuk, Ekaterina A. Orlova, Mikhail F. Vorovitch, Nikolay B. Pestov, Nick A. Barlev, Anna I. Levaniuk, Ilya V. Gordeychuk, Alexander S. Lunin, Grigory A. Demyashkin, Petr V. Shegai, Andrei D. Kaprin, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova

“…<b>Objective</b>: We evaluate the immunotherapeutic potential of the yellow fever virus vaccine strain 17D (YFV 17D) for intratumoral therapy of pancreatic cancer in mice. <b>Methods</b>: The cytopathic effect of YFV 17D on mouse syngeneic pancreatic cancers cells were studied both in vitro and in vivo and on human pancreatic cancers cells in vitro. …”
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Artificial neural network detection of pancreatic cancer from proton (1H) magnetic resonance spectroscopy patterns of plasma metabolites by Meiyappan Solaiyappan, Santosh Kumar Bharti, Raj Kumar Sharma, Mohamad Dbouk, Wasay Nizam, Malcolm V. Brock, Michael G. Goggins, Zaver M. Bhujwalla

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Longitudinal health-related quality of life in patients with pancreatic cancer stratified by treatment: a nationwide cohort studyResearch in context by Anne M. Gehrels, Pauline A.J. Vissers, Mirjam A.G. Sprangers, Nienke M. Fijnheer, Esther N. Pijnappel, Lydia G. van der Geest, Geert A. Cirkel, Judith de Vos-Geelen, Marjolein Y.V. Homs, Geert- Jan Creemers, Martijn W.J. Stommel, Lois A. Daamen, Marc G. Besselink, Johanna W. Wilmink, Hanneke W.M. van Laarhoven

Subjects: “…Pancreatic cancer…”
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RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression by Yihui Ma, Enjie Liu, Huijie Fan, Chenfei Li, Pei Huang, Meiying Cui, Zhengyang Wang, Jing Zhou, Kuisheng Chen

Subjects: “…Pancreatic cancer…”
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The Therapeutic Effect of Cytokine-Induced Killer Cells on Pancreatic Cancer Enhanced by Dendritic Cells Pulsed with K-Ras Mutant Peptide by Guang Tan, Xin Zhang, Hongbo Feng, Haifeng Luo, Zhongyu Wang

“…This study is to investigate the role of the CIKs cocultured with K-ras-DCs in killing of pancreatic cancer cell lines, PANC-1 (K-ras+) and SW1990 (K-ras−). …”
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Multi-omic biomarker panel in pancreatic cyst fluid and serum predicts patients at a high risk of pancreatic cancer development by Laura E. Kane, Gregory S. Mellotte, Eimear Mylod, Paul Dowling, Simone Marcone, Caitriona Scaife, Elaine M. Kenny, Michael Henry, Paula Meleady, Paul F. Ridgway, Finbar MacCarthy, Kevin C. Conlon, Barbara M. Ryan, Stephen G. Maher

Subjects: “…Pancreatic cancer…”
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Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

Subjects: “…Pancreatic cancer…”
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