Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. by Eiman Abdo, Mohammad A Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A Ababneh

“…<h4>Background</h4>Hypoxia in tumor cells is linked to increased drug resistance and more aggressive behavior. In pancreatic cancer, the tumor microenvironment is notably hypoxic and exhibits strong immunosuppressive properties. …”
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Comment on “Dynamics of Serum CA19-9 in Patients Undergoing Pancreatic Cancer Resection” by Xin Gao, MS, Zhiyao Fan, MD, Hanxiang Zhan, MD, PhD

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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer by Jilong Hu, Zhinan Zheng, Jia Lei, Yuxin Cao, Qiyun Li, Zhi Zheng, Chuanjun Chen

“…Enhancer of zeste homolog 2 (EZH2) is abnormally highly expressed in pancreatic cancer (PC). However, it is not ideal to treat PC by inhibiting EZH2. …”
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NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression by Wenchao Xu, Jianzhou Liu, Qiaofei Liu, Jia Xu, Li Zhou, Zhiyong Liang, Haoran Huang, Bowen Huang, Gary Guishan Xiao, Junchao Guo

“…Summary: Pancreatic cancer liver metastasis is an important factor leading to dismal prognoses. …”
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5 Fluorouracil‐loaded biosynthesised gold nanoparticles for the in vitro treatment of human pancreatic cancer cell by Senthil Kumar Chinnaiyan, Agnes Mary Soloman, Ramesh Kannan Perumal, Arun Gopinath, Madhan Balaraman

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Impact of Order Set on Exocrine Pancreatic Insufficiency in Chronic Pancreatitis, Pancreatic Cancer, and Pancreatic Resection by Michael Ladna, Ishaan Madhok, Adnan Bhat, Nicole Ruiz, Jackson Brown, Jake Wilson, Peter Jiang, Robert Taylor, Mark Radetic, John George, Christopher Forsmark

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The value of a metabolic and immune-related gene signature and adjuvant therapeutic response in pancreatic cancer by Danlei Ni, Jiayi Wu, Jingjing Pan, Yajing Liang, Zihui Xu, Zhiying Yan, Kequn Xu, Feifei Wei

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Early Detection of Pancreatic Cancer: Opportunities Provided by Cancer-induced Paraneoplastic Phenomena and Artificial Intelligence by Wei-Chih Liao

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Improving molecular subtypes and prognosis of pancreatic cancer through multi group analysis and machine learning by Xue-Jian Zhang, Fang-Fang Lin, Ya-Qing Wen, Kun-Ping Guan

Subjects: “…Pancreatic cancer…”
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Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis by Jiang Chen, Guo Xiao-Zhong, Xing-Shun Qi

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Bone Metastasis as the Only Metastatic Site in a Patient with Pancreatic Cancer following Distal Pancreatectomy by Muhammad Wasif Saif, Natalie Galanina, L. Ravage-Mass, Kristin Kaley, Daniel Cornfeld, Lynne Lamb, David Chhieng

“…Pancreatic cancer remains a challenge both diagnostically and therapeutically. …”
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Xanthoxyletin blocks the RANK/RANKL signaling pathway to suppress the growth of human pancreatic cancer cells by Zhang Xin, Li Luming, Wu Yan

Subjects: “…pancreatic cancer…”
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Clinical Analysis of Bloodstream Infection of Escherichia coli in Patients with Pancreatic Cancer from 2011 to 2019 by Changsen Bai, Xiuse Zhang, Dong Yang, Ding Li, Honglei Feng, Yueguo Li

“…We set out to find E. coli BSI’s risk factors in pancreatic cancer to provide valuable experience. Methods. …”
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

Subjects: “…Pancreatic cancer…”
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Correlations among PPAR𝜸, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Valerio Pazienza, Francesca Tavano, Giorgia Benegiamo, Manlio Vinciguerra, Francesca Paola Burbaci, Massimiliano Copetti, Fabio Francesco di Mola, Angelo Andriulli, Pierluigi di Sebastiano

“…In this study we aimed to evaluate the expression of PPARγ, DNMT1, and DNMT3B and their correlation with clinical-pathological features in patients with pancreatic cancer (PC), and to define the effect of PPARγ activation on DNMTs expression in PC cell lines. qRT-PCR analysis showed that DNMT3B expression was downregulated in tumors compared to normal tissues (𝑃=0.03), whereas PPARγ and DNMT1 levels did not show significant alterations in PC patients. …”
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Response to: Comment on “Dynamics of Serum CA 19-9 in Patients Undergoing Pancreatic Cancer Resection” by Vincent P. Groot, MD, PhD, Lois A. Daamen, MD, PhD

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The global, regional burden of pancreatic cancer and its attributable risk factors from 1990 to 2021 by Weidong Yu, Danyi Zhou, Fanhao Meng, Jinjing Wang, Bo Wang, Jianling Qiang, Lijun Shen, Maofeng Wang, Hezhi Fang

Subjects: “…Pancreatic cancer…”
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Treatment and Outcomes of Pancreatic Cancer in Armenia: A Retrospective Study From Resource-Limited Settings by Elen Baloyan, Davit Zohrabyan, Liana Safaryan, Armen Avagyan, Lilit Harutyunyan, Vardan Bardakhchyan, Jemma Arakelyan, Amalya Sargsyan, Martin Harutyunyan, Mariam Mailyan, Gevorg Tamamyan, Samvel Bardakhchyan

“…The information was obtained from the medical records of the patients with pancreatic cancer treated at these centers during January 1, 2010-January 1, 2022. …”
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Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression by Hao Hua, Yazu Deng, Dijie Zheng, Changhao Wu, Liwen Chen, Binbin Shi, Zhiwei He, Chao Yu

Subjects: “…Pancreatic cancer…”
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Assessment of Nutritional Status, Digestion and Absorption, and Quality of Life in Patients with Locally Advanced Pancreatic Cancer by J. E. Witvliet-van Nierop, C. M. Lochtenberg-Potjes, N. J. Wierdsma, H. J. Scheffer, G. Kazemier, K. Ottens-Oussoren, M. R. Meijerink, M. A. E. de van der Schueren

“…To provide a comprehensive quantitative assessment of nutritional status, digestion and absorption, and quality of life (QoL) in patients with locally advanced pancreatic cancer (LAPC). Methods. Sixteen patients with LAPC were prospectively assessed for weight loss (WL), body mass index (BMI), fat-free mass index (FFMI), handgrip strength (HGS), dietary macronutrient intake, serum vitamin levels, resting and total energy expenditure (REE and TEE, indirect calorimetry), intestinal absorption capacity and fecal losses (bomb calorimetry), exocrine pancreatic function (fecal elastase-1 (FE1)), and gastrointestinal quality of life (GIQLI). …”
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